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Items: 1 to 50 of 77

1.

JAK inhibition increases bone mass in steady-state conditions and ameliorates pathological bone loss by stimulating osteoblast function.

Adam S, Simon N, Steffen U, Andes FT, Scholtysek C, Müller DIH, Weidner D, Andreev D, Kleyer A, Culemann S, Hahn M, Schett G, Krönke G, Frey S, Hueber AJ.

Sci Transl Med. 2020 Feb 12;12(530). pii: eaay4447. doi: 10.1126/scitranslmed.aay4447.

PMID:
32051226
2.

Structural insights into heme binding to IL-36α proinflammatory cytokine.

Wißbrock A, Goradia NB, Kumar A, Paul George AA, Kühl T, Bellstedt P, Ramachandran R, Hoffmann P, Galler K, Popp J, Neugebauer U, Hampel K, Zimmermann B, Adam S, Wiendl M, Krönke G, Hamza I, Heinemann SH, Frey S, Hueber AJ, Ohlenschläger O, Imhof D.

Sci Rep. 2019 Nov 15;9(1):16893. doi: 10.1038/s41598-019-53231-0.

3.

Factors and Situations Affecting the Value of Patient Preference Studies: Semi-Structured Interviews in Europe and the US.

Whichello C, van Overbeeke E, Janssens R, Schölin Bywall K, Russo S, Veldwijk J, Cleemput I, Juhaeri J, Levitan B, Kübler J, Smith M, Hermann R, Englbrecht M, Hueber AJ, Comanescu A, Harding S, Simoens S, Huys I, de Bekker-Grob EW.

Front Pharmacol. 2019 Sep 18;10:1009. doi: 10.3389/fphar.2019.01009. eCollection 2019.

4.

[Hand pain, muscle pain and swollen lips].

d'Oliveira I, Döltz S, Manger K, Hueber AJ.

Z Rheumatol. 2019 Sep;78(7):656-659. doi: 10.1007/s00393-019-0679-7. German. No abstract available.

PMID:
31359144
5.

Disease interception with interleukin-17 inhibition in high-risk psoriasis patients with subclinical joint inflammation-data from the prospective IVEPSA study.

Kampylafka E, Simon D, d'Oliveira I, Linz C, Lerchen V, Englbrecht M, Rech J, Kleyer A, Sticherling M, Schett G, Hueber AJ.

Arthritis Res Ther. 2019 Jul 26;21(1):178. doi: 10.1186/s13075-019-1957-0.

6.

Effect of disease-modifying anti-rheumatic drugs on bone structure and strength in psoriatic arthritis patients.

Simon D, Kleyer A, Bayat S, Tascilar K, Kampylafka E, Meinderink T, Schuster L, Petrov R, Liphardt AM, Rech J, Schett G, Hueber AJ.

Arthritis Res Ther. 2019 Jul 3;21(1):162. doi: 10.1186/s13075-019-1938-3.

7.

The ageing joint-standard age- and sex-related values of bone erosions and osteophytes in the hand joints of healthy individuals.

Berlin A, Simon D, Tascilar K, Figueiredo C, Bayat S, Finzel S, Klaus E, Rech J, Hueber AJ, Kleyer A, Schett G.

Osteoarthritis Cartilage. 2019 Jul;27(7):1043-1047. doi: 10.1016/j.joca.2019.01.019. Epub 2019 Mar 16.

PMID:
30890457
8.

I would never take preventive medication! Perspectives and information needs of people who underwent predictive tests for rheumatoid arthritis.

Mosor E, Stoffer-Marx M, Steiner G, Raza K, Stack RJ, Simons G, Falahee M, Skingle D, Dobrin M, Schett G, Englbrecht M, Smolen JS, Kjeken I, Hueber AJ, Stamm TA.

Arthritis Care Res (Hoboken). 2019 Feb 2. doi: 10.1002/acr.23841. [Epub ahead of print]

9.

["Virtual rheumatology" : A new teaching concept for rheumatology of the future?]

Kleyer A, Simon D, Hartmann F, Schuster L, Hueber AJ.

Z Rheumatol. 2019 Mar;78(2):112-115. doi: 10.1007/s00393-019-0594-y. German. No abstract available.

PMID:
30694358
10.

[Use of medical apps and online platforms among German rheumatologists : Results of the 2016 and 2018 DGRh conference surveys and research conducted by rheumadocs].

Knitza J, Vossen D, Geffken I, Krusche M, Meyer M, Sewerin P, Kleyer A, Hueber AJ; Arbeitskreis Junge Rheumatologen.

Z Rheumatol. 2019 Nov;78(9):839-846. doi: 10.1007/s00393-018-0578-3. German.

PMID:
30542914
11.

Low-Dose Radiotherapy Ameliorates Advanced Arthritis in hTNF-α tg Mice by Particularly Positively Impacting on Bone Metabolism.

Deloch L, Derer A, Hueber AJ, Herrmann M, Schett GA, Wölfelschneider J, Hahn J, Rühle PF, Stillkrieg W, Fuchs J, Fietkau R, Frey B, Gaipl US.

Front Immunol. 2018 Sep 18;9:1834. doi: 10.3389/fimmu.2018.01834. eCollection 2018.

12.

Simultaneous quantification of bone erosions and enthesiophytes in the joints of patients with psoriasis or psoriatic arthritis - effects of age and disease duration.

Simon D, Kleyer A, Faustini F, Englbrecht M, Haschka J, Berlin A, Kraus S, Hueber AJ, Kocijan R, Sticherling M, Rech J, Schett G.

Arthritis Res Ther. 2018 Aug 31;20(1):203. doi: 10.1186/s13075-018-1691-z.

13.

Resolution of synovitis and arrest of catabolic and anabolic bone changes in patients with psoriatic arthritis by IL-17A blockade with secukinumab: results from the prospective PSARTROS study.

Kampylafka E, d'Oliveira I, Linz C, Lerchen V, Stemmler F, Simon D, Englbrecht M, Sticherling M, Rech J, Kleyer A, Schett G, Hueber AJ.

Arthritis Res Ther. 2018 Jul 27;20(1):153. doi: 10.1186/s13075-018-1653-5.

14.

A comparative analysis of articular bone in large cohort of patients with chronic inflammatory diseases of the joints, the gut and the skin.

Simon D, Kleyer A, Englbrecht M, Stemmler F, Simon C, Berlin A, Kocijan R, Haschka J, Hirschmann S, Atreya R, Neurath MF, Sticherling M, Rech J, Hueber AJ, Engelke K, Schett G.

Bone. 2018 Nov;116:87-93. doi: 10.1016/j.bone.2018.07.017. Epub 2018 Jul 23.

PMID:
30048820
15.

[Novel molecular mechanisms in the pathophysiology of psoriatic arthritis].

Simon D, Kampylafka E, Hueber AJ.

Z Rheumatol. 2018 Nov;77(9):776-782. doi: 10.1007/s00393-018-0503-9. Review. German.

PMID:
30003319
16.

ALIGNed on adherence: subanalysis of adherence in immune-mediated inflammatory diseases in the DACH region of the global ALIGN study.

Kolios AGA, Hueber AJ, Michetti P, Mrowietz U, Mustak-Blagusz M, Sator PG, Reinshagen M, Wilsmann-Theis D, Gomis-Kleindienst S, Luckey U, Rössler A, Schiefke I.

J Eur Acad Dermatol Venereol. 2019 Jan;33(1):234-241. doi: 10.1111/jdv.15179. Epub 2018 Aug 22.

17.

Biomechanical properties of bone are impaired in patients with ACPA-positive rheumatoid arthritis and associated with the occurrence of fractures.

Stemmler F, Simon D, Liphardt AM, Englbrecht M, Rech J, Hueber AJ, Engelke K, Schett G, Kleyer A.

Ann Rheum Dis. 2018 Jul;77(7):973-980. doi: 10.1136/annrheumdis-2017-212404. Epub 2018 Feb 23.

18.

[Big data in imaging].

Sewerin P, Ostendorf B, Hueber AJ, Kleyer A.

Z Rheumatol. 2018 Apr;77(3):203-208. doi: 10.1007/s00393-018-0422-9. Review. German.

PMID:
29411097
19.

Methods for segmentation of rheumatoid arthritis bone erosions in high-resolution peripheral quantitative computed tomography (HR-pQCT).

Figueiredo CP, Kleyer A, Simon D, Stemmler F, d'Oliveira I, Weissenfels A, Museyko O, Friedberger A, Hueber AJ, Haschka J, Englbrecht M, Pereira RMR, Rech J, Schett G, Engelke K.

Semin Arthritis Rheum. 2018 Apr;47(5):611-618. doi: 10.1016/j.semarthrit.2017.09.011. Epub 2017 Sep 23.

PMID:
29122245
20.

Unilateral plantar erythema nodosum in sarcoidosis.

Hueber AJ, Schett G, Manger B.

Arthritis Rheumatol. 2018 Feb;70(2):297. doi: 10.1002/art.40341. Epub 2018 Jan 5. No abstract available.

21.

Interleukin-36 receptor mediates the crosstalk between plasma cells and synovial fibroblasts.

Schmitt V, Hahn M, Kästele V, Wagner O, Wiendl M, Derer A, Taddeo A, Hahne S, Radbruch A, Jäck HM, Schuh W, Mielenz D, Gay S, Schett G, Hueber AJ, Frey S.

Eur J Immunol. 2017 Dec;47(12):2101-2112. doi: 10.1002/eji.201646788. Epub 2017 Sep 22.

22.

Full Length Interleukin 33 Aggravates Radiation-Induced Skin Reaction.

Kurow O, Frey B, Schuster L, Schmitt V, Adam S, Hahn M, Gilchrist D, McInnes IB, Wirtz S, Gaipl US, Krönke G, Schett G, Frey S, Hueber AJ.

Front Immunol. 2017 Jun 28;8:722. doi: 10.3389/fimmu.2017.00722. eCollection 2017.

23.

Early Changes of the Cortical Micro-Channel System in the Bare Area of the Joints of Patients With Rheumatoid Arthritis.

Werner D, Simon D, Englbrecht M, Stemmler F, Simon C, Berlin A, Haschka J, Renner N, Buder T, Engelke K, Hueber AJ, Rech J, Schett G, Kleyer A.

Arthritis Rheumatol. 2017 Aug;69(8):1580-1587. doi: 10.1002/art.40148. Epub 2017 Jun 26.

24.

Development of three-dimensional prints of arthritic joints for supporting patients' awareness to structural damage.

Kleyer A, Beyer L, Simon C, Stemmler F, Englbrecht M, Beyer C, Rech J, Manger B, Krönke G, Schett G, Hueber AJ.

Arthritis Res Ther. 2017 Feb 10;19(1):34. doi: 10.1186/s13075-017-1234-z.

25.

The novel interleukin-1 cytokine family members in inflammatory diseases.

Hahn M, Frey S, Hueber AJ.

Curr Opin Rheumatol. 2017 Mar;29(2):208-213. doi: 10.1097/BOR.0000000000000361. Review.

PMID:
27926540
26.

Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease.

Pfeifle R, Rothe T, Ipseiz N, Scherer HU, Culemann S, Harre U, Ackermann JA, Seefried M, Kleyer A, Uderhardt S, Haugg B, Hueber AJ, Daum P, Heidkamp GF, Ge C, Böhm S, Lux A, Schuh W, Magorivska I, Nandakumar KS, Lönnblom E, Becker C, Dudziak D, Wuhrer M, Rombouts Y, Koeleman CA, Toes R, Winkler TH, Holmdahl R, Herrmann M, Blüml S, Nimmerjahn F, Schett G, Krönke G.

Nat Immunol. 2017 Jan;18(1):104-113. doi: 10.1038/ni.3579. Epub 2016 Nov 7.

27.

Age- and Sex-Dependent Changes of Intra-articular Cortical and Trabecular Bone Structure and the Effects of Rheumatoid Arthritis.

Simon D, Kleyer A, Stemmler F, Simon C, Berlin A, Hueber AJ, Haschka J, Renner N, Figueiredo C, Neuhuber W, Buder T, Englbrecht M, Rech J, Engelke K, Schett G.

J Bone Miner Res. 2017 Apr;32(4):722-730. doi: 10.1002/jbmr.3025. Epub 2016 Nov 18.

28.

Antimodified protein antibody response pattern influences the risk for disease relapse in patients with rheumatoid arthritis tapering disease modifying antirheumatic drugs.

Figueiredo CP, Bang H, Cobra JF, Englbrecht M, Hueber AJ, Haschka J, Manger B, Kleyer A, Reiser M, Finzel S, Tony HP, Kleinert S, Wendler J, Schuch F, Ronneberger M, Feuchtenberger M, Fleck M, Manger K, Ochs W, Schmitt-Haendle M, Lorenz HM, Nuesslein H, Alten R, Henes J, Krueger K, Rech J, Schett G.

Ann Rheum Dis. 2017 Feb;76(2):399-407. doi: 10.1136/annrheumdis-2016-209297. Epub 2016 Jun 20.

PMID:
27323772
29.

Subclinical joint inflammation in patients with psoriasis without concomitant psoriatic arthritis: a cross-sectional and longitudinal analysis.

Faustini F, Simon D, Oliveira I, Kleyer A, Haschka J, Englbrecht M, Cavalcante AR, Kraus S, Tabosa TP, Figueiredo C, Hueber AJ, Kocijan R, Cavallaro A, Schett G, Sticherling M, Rech J.

Ann Rheum Dis. 2016 Dec;75(12):2068-2074. doi: 10.1136/annrheumdis-2015-208821. Epub 2016 Feb 25.

PMID:
26916344
30.

Prevalence of monosodium urate deposits in a population of rheumatoid arthritis patients with hyperuricemia.

Petsch C, Araujo EG, Englbrecht M, Bayat S, Cavallaro A, Hueber AJ, Lell M, Schett G, Manger B, Rech J.

Semin Arthritis Rheum. 2016 Jun;45(6):663-8. doi: 10.1016/j.semarthrit.2015.11.014. Epub 2015 Dec 2.

PMID:
26743072
31.

Tophus resolution with pegloticase: a prospective dual-energy CT study.

Araujo EG, Bayat S, Petsch C, Englbrecht M, Faustini F, Kleyer A, Hueber AJ, Cavallaro A, Lell M, Dalbeth N, Manger B, Schett G, Rech J.

RMD Open. 2015 Jun 17;1(1):e000075. doi: 10.1136/rmdopen-2015-000075. eCollection 2015.

32.

Prediction of disease relapses by multibiomarker disease activity and autoantibody status in patients with rheumatoid arthritis on tapering DMARD treatment.

Rech J, Hueber AJ, Finzel S, Englbrecht M, Haschka J, Manger B, Kleyer A, Reiser M, Cobra JF, Figueiredo C, Tony HP, Kleinert S, Wendler J, Schuch F, Ronneberger M, Feuchtenberger M, Fleck M, Manger K, Ochs W, Schmitt-Haendle M, Lorenz HM, Nuesslein H, Alten R, Henes J, Krueger K, Schett G.

Ann Rheum Dis. 2016 Sep;75(9):1637-44. doi: 10.1136/annrheumdis-2015-207900. Epub 2015 Oct 19.

33.

A comparative analysis of magnetic resonance imaging and high-resolution peripheral quantitative computed tomography of the hand for the detection of erosion repair in rheumatoid arthritis.

Regensburger A, Rech J, Englbrecht M, Finzel S, Kraus S, Hecht K, Kleyer A, Haschka J, Hueber AJ, Cavallaro A, Schett G, Faustini F.

Rheumatology (Oxford). 2015 Sep;54(9):1573-81. doi: 10.1093/rheumatology/kev031. Epub 2015 Mar 31.

PMID:
25832611
34.

Relapse rates in patients with rheumatoid arthritis in stable remission tapering or stopping antirheumatic therapy: interim results from the prospective randomised controlled RETRO study.

Haschka J, Englbrecht M, Hueber AJ, Manger B, Kleyer A, Reiser M, Finzel S, Tony HP, Kleinert S, Feuchtenberger M, Fleck M, Manger K, Ochs W, Schmitt-Haendle M, Wendler J, Schuch F, Ronneberger M, Lorenz HM, Nuesslein H, Alten R, Demary W, Henes J, Schett G, Rech J.

Ann Rheum Dis. 2016 Jan;75(1):45-51. doi: 10.1136/annrheumdis-2014-206439. Epub 2015 Feb 6.

PMID:
25660991
35.

Analysis of periarticular bone changes in patients with cutaneous psoriasis without associated psoriatic arthritis.

Simon D, Faustini F, Kleyer A, Haschka J, Englbrecht M, Kraus S, Hueber AJ, Kocijan R, Sticherling M, Schett G, Rech J.

Ann Rheum Dis. 2016 Apr;75(4):660-6. doi: 10.1136/annrheumdis-2014-206347. Epub 2015 Feb 4.

PMID:
25653201
36.

High degree of nonadherence to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis.

Rauscher V, Englbrecht M, van der Heijde D, Schett G, Hueber AJ.

J Rheumatol. 2015 Mar;42(3):386-90. doi: 10.3899/jrheum.140982. Epub 2015 Jan 15.

PMID:
25593229
37.

No evidence of pathogenic involvement of cathelicidins in patient cohorts and mouse models of lupus and arthritis.

Kienhöfer D, Hahn J, Schubert I, Reinwald C, Ipseiz N, Lang SC, Borràs ÈB, Amann K, Sjöwall C, Barron AE, Hueber AJ, Agerberth B, Schett G, Hoffmann MH.

PLoS One. 2014 Dec 23;9(12):e115474. doi: 10.1371/journal.pone.0115474. eCollection 2014.

38.

Rsk2 controls synovial fibroblast hyperplasia and the course of arthritis.

Derer A, Böhm C, Grötsch B, Grün JR, Grützkau A, Stock M, Böhm S, Sehnert B, Gaipl U, Schett G, Hueber AJ, David JP.

Ann Rheum Dis. 2016 Feb;75(2):413-21. doi: 10.1136/annrheumdis-2014-205618. Epub 2014 Nov 20.

PMID:
25414238
39.

Combined inhibition of tumor necrosis factor α and interleukin-17 as a therapeutic opportunity in rheumatoid arthritis: development and characterization of a novel bispecific antibody.

Fischer JA, Hueber AJ, Wilson S, Galm M, Baum W, Kitson C, Auer J, Lorenz SH, Moelleken J, Bader M, Tissot AC, Tan SL, Seeber S, Schett G.

Arthritis Rheumatol. 2015 Jan;67(1):51-62. doi: 10.1002/art.38896.

40.

Blockade of IL-36 receptor signaling does not prevent from TNF-induced arthritis.

Derer A, Groetsch B, Harre U, Böhm C, Towne J, Schett G, Frey S, Hueber AJ.

PLoS One. 2014 Aug 11;9(8):e101954. doi: 10.1371/journal.pone.0101954. eCollection 2014.

41.

[New aspects on the pathogenesis of psoriatic arthritis].

Hueber AJ, Manger B.

Z Rheumatol. 2013 Oct;72(8):758-63. doi: 10.1007/s00393-013-1186-x. German.

PMID:
24046231
42.

Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies.

Kleyer A, Finzel S, Rech J, Manger B, Krieter M, Faustini F, Araujo E, Hueber AJ, Harre U, Engelke K, Schett G.

Ann Rheum Dis. 2014 May;73(5):854-60. doi: 10.1136/annrheumdis-2012-202958. Epub 2013 Mar 21.

PMID:
23520034
43.

The novel cytokine interleukin-36α is expressed in psoriatic and rheumatoid arthritis synovium.

Frey S, Derer A, Messbacher ME, Baeten DL, Bugatti S, Montecucco C, Schett G, Hueber AJ.

Ann Rheum Dis. 2013 Sep 1;72(9):1569-74. doi: 10.1136/annrheumdis-2012-202264. Epub 2012 Dec 25.

PMID:
23268368
44.

MicroRNA-155 as a proinflammatory regulator in clinical and experimental arthritis.

Kurowska-Stolarska M, Alivernini S, Ballantine LE, Asquith DL, Millar NL, Gilchrist DS, Reilly J, Ierna M, Fraser AR, Stolarski B, McSharry C, Hueber AJ, Baxter D, Hunter J, Gay S, Liew FY, McInnes IB.

Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11193-8. doi: 10.1073/pnas.1019536108. Epub 2011 Jun 20.

45.

IL-33 induces skin inflammation with mast cell and neutrophil activation.

Hueber AJ, Alves-Filho JC, Asquith DL, Michels C, Millar NL, Reilly JH, Graham GJ, Liew FY, Miller AM, McInnes IB.

Eur J Immunol. 2011 Aug;41(8):2229-37. doi: 10.1002/eji.201041360. Epub 2011 Jun 24.

46.

Nanoparticles and inflammation.

Stevenson R, Hueber AJ, Hutton A, McInnes IB, Graham D.

ScientificWorldJournal. 2011 Jun 9;11:1300-12. doi: 10.1100/tsw.2011.106. Review.

47.

An investigation of the inflammatory cytokine and chemokine network in systemic sclerosis.

Codullo V, Baldwin HM, Singh MD, Fraser AR, Wilson C, Gilmour A, Hueber AJ, Bonino C, McInnes IB, Montecucco C, Graham GJ.

Ann Rheum Dis. 2011 Jun;70(6):1115-21. doi: 10.1136/ard.2010.137349. Epub 2011 Feb 1.

PMID:
21285114
48.

Embracing novel cytokines in RA - complexity grows as does opportunity!

Hueber AJ, Asquith DL, McInnes IB, Miller AM.

Best Pract Res Clin Rheumatol. 2010 Aug;24(4):479-87. doi: 10.1016/j.berh.2010.01.004. Review.

PMID:
20732646
49.

Interleukin-33 induces protective effects in adipose tissue inflammation during obesity in mice.

Miller AM, Asquith DL, Hueber AJ, Anderson LA, Holmes WM, McKenzie AN, Xu D, Sattar N, McInnes IB, Liew FY.

Circ Res. 2010 Sep 3;107(5):650-8. doi: 10.1161/CIRCRESAHA.110.218867. Epub 2010 Jul 15.

50.

Inflammation is present in early human tendinopathy.

Millar NL, Hueber AJ, Reilly JH, Xu Y, Fazzi UG, Murrell GA, McInnes IB.

Am J Sports Med. 2010 Oct;38(10):2085-91. doi: 10.1177/0363546510372613. Epub 2010 Jul 1.

PMID:
20595553

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