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Evaluation of multiple sclerosis disability outcome measures using pooled clinical trial data.

Goldman MD, LaRocca NG, Rudick RA, Hudson LD, Chin PS, Francis GS, Jacobs A, Kapoor R, Matthews PM, Mowry EM, Balcer LJ, Panzara M, Phillips G, Uitdehaag BMJ, Cohen JA; Multiple Sclerosis Outcome Assessments Consortium.

Neurology. 2019 Oct 22. pii: 10.1212/WNL.0000000000008519. doi: 10.1212/WNL.0000000000008519. [Epub ahead of print]


Mental health delivery in schools and the NHS long-term plan.

Hudson LD.

Clin Child Psychol Psychiatry. 2019 Oct;24(4):658-660. doi: 10.1177/1359104519871129. No abstract available.


Roles of cyberbullying, sleep, and physical activity in mediating the effects of social media use on mental health and wellbeing among young people in England: a secondary analysis of longitudinal data.

Viner RM, Gireesh A, Stiglic N, Hudson LD, Goddings AL, Ward JL, Nicholls DE.

Lancet Child Adolesc Health. 2019 Oct;3(10):685-696. doi: 10.1016/S2352-4642(19)30186-5. Epub 2019 Aug 13. Erratum in: Lancet Child Adolesc Health. 2019 Oct 31;:.


Symbol Digit Modalities Test: A valid clinical trial endpoint for measuring cognition in multiple sclerosis.

Strober L, DeLuca J, Benedict RH, Jacobs A, Cohen JA, Chiaravalloti N, Hudson LD, Rudick RA, LaRocca NG; Multiple Sclerosis Outcome Assessments Consortium (MSOAC).

Mult Scler. 2019 Nov;25(13):1781-1790. doi: 10.1177/1352458518808204. Epub 2018 Oct 18.


Sharing Data to Accelerate Medicine Development and Improve Neonatal Care: Data Standards and Harmonized Definitions.

Costeloe K, Turner MA, Padula MA, Shah PS, Modi N, Soll R, Haumont D, Kusuda S, Göpel W, Chang YS, Smith PB, Lui K, Davis JM, Hudson LD; International Neonatal Consortium.

J Pediatr. 2018 Dec;203:437-441.e1. doi: 10.1016/j.jpeds.2018.07.082. Epub 2018 Oct 4. No abstract available.


Global Standards to Expedite Learning From Medical Research Data.

Hudson LD, Kush RD, Navarro Almario E, Seigneuret N, Jackson T, Jauregui B, Jordan D, Fitzmartin R, Zhou FL, Malone JK, Galvez J, Becnel LB.

Clin Transl Sci. 2018 Jul;11(4):342-344. doi: 10.1111/cts.12556. Epub 2018 Apr 26. No abstract available.


Cost-effectiveness of a community-delivered multicomponent intervention compared with enhanced standard care of obese adolescents: cost-utility analysis alongside a randomised controlled trial (the HELP trial).

Panca M, Christie D, Cole TJ, Costa S, Gregson J, Holt R, Hudson LD, Kessel AS, Kinra S, Mathiot A, Nazareth I, Wataranan J, Wong ICK, Viner RM, Morris S.

BMJ Open. 2018 Feb 15;8(2):e018640. doi: 10.1136/bmjopen-2017-018640.


Application of a Dynamic Map for Learning, Communicating, Navigating, and Improving Therapeutic Development.

Wagner JA, Dahlem AM, Hudson LD, Terry SF, Altman RB, Gilliland CT, DeFeo C, Austin CP.

Clin Transl Sci. 2018 Mar;11(2):166-174. doi: 10.1111/cts.12531. Epub 2017 Dec 22.


A dynamic map for learning, communicating, navigating and improving therapeutic development.

Wagner J, Dahlem AM, Hudson LD, Terry SF, Altman RB, Gilliland CT, DeFeo C, Austin CP.

Nat Rev Drug Discov. 2018 Feb;17(2):150. doi: 10.1038/nrd.2017.217. Epub 2017 Dec 22. No abstract available.


Biometric monitoring devices for assessing end points in clinical trials: developing an ecosystem.

Arnerić SP, Cedarbaum JM, Khozin S, Papapetropoulos S, Hill DL, Ropacki M, Rhodes J, Dacks PA, Hudson LD, Gordon MF, Kern VD, Romero K, Vradenburg G, Au R, Karlin DR, Facheris MF, Fitzer-Attas CJ, Vitolo OV, Wang J, Miller BM, Kaye JA.

Nat Rev Drug Discov. 2017 Oct;16(10):736. doi: 10.1038/nrd.2017.153. Epub 2017 Sep 22. No abstract available.


The MSOAC approach to developing performance outcomes to measure and monitor multiple sclerosis disability.

LaRocca NG, Hudson LD, Rudick R, Amtmann D, Balcer L, Benedict R, Bermel R, Chang I, Chiaravalloti ND, Chin P, Cohen JA, Cutter GR, Davis MD, DeLuca J, Feys P, Francis G, Goldman MD, Hartley E, Kapoor R, Lublin F, Lundstrom G, Matthews PM, Mayo N, Meibach R, Miller DM, Motl RW, Mowry EM, Naismith R, Neville J, Panagoulias J, Panzara M, Phillips G, Robbins A, Sidovar MF, Smith KE, Sperling B, Uitdehaag BM, Weaver J; Multiple Sclerosis Outcome Assessments Consortium (MSOAC).

Mult Scler. 2018 Oct;24(11):1469-1484. doi: 10.1177/1352458517723718. Epub 2017 Aug 11. Review.


A community-based motivational personalised lifestyle intervention to reduce BMI in obese adolescents: results from the Healthy Eating and Lifestyle Programme (HELP) randomised controlled trial.

Christie D, Hudson LD, Kinra S, Wong ICK, Nazareth I, Cole TJ, Sovio U, Gregson J, Kessel AS, Mathiot A, Morris S, Panca M, Costa S, Holt R, Viner RM.

Arch Dis Child. 2017 Aug;102(8):695-701. doi: 10.1136/archdischild-2016-311586. Epub 2017 Jul 7.


Arterial stiffening, insulin resistance and acanthosis nigricans in a community sample of adolescents with obesity.

Hudson LD, Kinra S, Wong ICK, Viner RM.

Int J Obes (Lond). 2017 Sep;41(9):1454-1456. doi: 10.1038/ijo.2017.105. Epub 2017 May 3.


Validity of the timed 25-foot walk as an ambulatory performance outcome measure for multiple sclerosis.

Motl RW, Cohen JA, Benedict R, Phillips G, LaRocca N, Hudson LD, Rudick R; Multiple Sclerosis Outcome Assessments Consortium.

Mult Scler. 2017 Apr;23(5):704-710. doi: 10.1177/1352458517690823. Epub 2017 Feb 16.


Validity of the Symbol Digit Modalities Test as a cognition performance outcome measure for multiple sclerosis.

Benedict RH, DeLuca J, Phillips G, LaRocca N, Hudson LD, Rudick R; Multiple Sclerosis Outcome Assessments Consortium.

Mult Scler. 2017 Apr;23(5):721-733. doi: 10.1177/1352458517690821. Epub 2017 Feb 16.


The Nine-Hole Peg Test as a manual dexterity performance measure for multiple sclerosis.

Feys P, Lamers I, Francis G, Benedict R, Phillips G, LaRocca N, Hudson LD, Rudick R; Multiple Sclerosis Outcome Assessments Consortium.

Mult Scler. 2017 Apr;23(5):711-720. doi: 10.1177/1352458517690824. Epub 2017 Feb 16.


The International Neonatal Consortium: collaborating to advance regulatory science for neonates.

Turner MA, Davis JM, McCune S, Bax R, Portman RJ, Hudson LD.

Pediatr Res. 2016 Oct;80(4):462-4. doi: 10.1038/pr.2016.119. Epub 2016 Jun 8. No abstract available.


Evidence for contemporary arterial stiffening in obese children and adolescents using pulse wave velocity: A systematic review and meta-analysis.

Hudson LD, Rapala A, Khan T, Williams B, Viner RM.

Atherosclerosis. 2015 Aug;241(2):376-86. doi: 10.1016/j.atherosclerosis.2015.05.014. Epub 2015 May 19. Review.


The trouble with z-scores: response to Faje et al.'s paper: "Fracture risk and areal bone mineral density in adolescent females with anorexia nervosa".

Hudson LD, Kennedy A, Chapman S.

Int J Eat Disord. 2014 Jul;47(5):562. doi: 10.1002/eat.22262. Epub 2014 Mar 20. No abstract available.


Multiple Sclerosis Outcome Assessments Consortium: Genesis and initial project plan.

Rudick RA, Larocca N, Hudson LD; MSOAC.

Mult Scler. 2014 Jan;20(1):12-7. doi: 10.1177/1352458513503392. Epub 2013 Sep 20. Review.


Long-term sequelae of childhood bacterial meningitis.

Hudson LD, Viner RM, Christie D.

Curr Infect Dis Rep. 2013 Jun;15(3):236-41. doi: 10.1007/s11908-013-0332-6.


Low levels of knowledge on the assessment of underweight in children and adolescents among middle-grade doctors in England and Wales.

Hudson LD, Cumby C, Klaber RE, Nicholls DE, Winyard PJ, Viner RM.

Arch Dis Child. 2013 Apr;98(4):309-11. doi: 10.1136/archdischild-2012-303357. Epub 2013 Jan 31.


Diurnal sedative changes during intensive care: impact on liberation from mechanical ventilation and delirium.

Seymour CW, Pandharipande PP, Koestner T, Hudson LD, Thompson JL, Shintani AK, Ely EW, Girard TD.

Crit Care Med. 2012 Oct;40(10):2788-96.


Medical instability and growth of children and adolescents with early onset eating disorders.

Hudson LD, Nicholls DE, Lynn RM, Viner RM.

Arch Dis Child. 2012 Sep;97(9):779-84. doi: 10.1136/archdischild-2011-301055. Epub 2012 Jun 19.


Thermodynamics of Zn2+ binding to Cys2His2 and Cys2HisCys zinc fingers and a Cys4 transcription factor site.

Rich AM, Bombarda E, Schenk AD, Lee PE, Cox EH, Spuches AM, Hudson LD, Kieffer B, Wilcox DE.

J Am Chem Soc. 2012 Jun 27;134(25):10405-18. doi: 10.1021/ja211417g. Epub 2012 Jun 14.


What paediatricians should know about eating disorders in children and young people.

Hudson LD, Court AJ.

J Paediatr Child Health. 2012 Oct;48(10):869-75. doi: 10.1111/j.1440-1754.2012.02433.x. Epub 2012 Mar 7. Review.


The genetic signature of perineuronal oligodendrocytes reveals their unique phenotype.

Szuchet S, Nielsen JA, Lovas G, Domowicz MS, de Velasco JM, Maric D, Hudson LD.

Eur J Neurosci. 2011 Dec;34(12):1906-22. doi: 10.1111/j.1460-9568.2011.07922.x. Epub 2011 Dec 2.


Riots in the streets. Putting young people's behaviour in perspective.

Hudson LD, Stephenson T, Christie D, Viner R.

BMJ. 2011 Sep 20;343:d5841. doi: 10.1136/bmj.d5841. No abstract available.


Mouse transmembrane BAX inhibitor motif 3 (Tmbim3) encodes a 38 kDa transmembrane protein expressed in the central nervous system.

Nielsen JA, Chambers MA, Romm E, Lee LY, Berndt JA, Hudson LD.

Mol Cell Biochem. 2011 Nov;357(1-2):73-81. doi: 10.1007/s11010-011-0877-3. Epub 2011 May 26.


A tool for examining the role of the zinc finger myelin transcription factor 1 (Myt1) in neural development: Myt1 knock-in mice.

Hudson LD, Romm E, Berndt JA, Nielsen JA.

Transgenic Res. 2011 Aug;20(4):951-61. doi: 10.1007/s11248-010-9470-x. Epub 2011 Jan 26.


Age-, sex-, and race-based differences among patients enrolled versus not enrolled in acute lung injury clinical trials.

Cooke CR, Erickson SE, Watkins TR, Matthay MA, Hudson LD, Rubenfeld GD.

Crit Care Med. 2010 Jun;38(6):1450-7. doi: 10.1097/CCM.0b013e3181de451b.


MicroRNAs in neural cell differentiation.

Lau P, Hudson LD.

Brain Res. 2010 Jun 18;1338:14-9. doi: 10.1016/j.brainres.2010.04.002. Epub 2010 Apr 9. Review.


Alterations in neuronal gene expression profiles in response to experimental demyelination and axonal transection.

Lovas G, Nielsen JA, Johnson KR, Hudson LD.

Mult Scler. 2010 Mar;16(3):303-16. doi: 10.1177/1352458509357063. Epub 2010 Jan 19.


Integrating microRNA and mRNA expression profiles of neuronal progenitors to identify regulatory networks underlying the onset of cortical neurogenesis.

Nielsen JA, Lau P, Maric D, Barker JL, Hudson LD.

BMC Neurosci. 2009 Aug 19;10:98. doi: 10.1186/1471-2202-10-98.


Tubulin polymerization-promoting protein (TPPP/p25) is critical for oligodendrocyte differentiation.

Lehotzky A, Lau P, Tokési N, Muja N, Hudson LD, Ovádi J.

Glia. 2010 Jan 15;58(2):157-68. doi: 10.1002/glia.20909.


Cost-effectiveness of implementing low-tidal volume ventilation in patients with acute lung injury.

Cooke CR, Kahn JM, Watkins TR, Hudson LD, Rubenfeld GD.

Chest. 2009 Jul;136(1):79-88. doi: 10.1378/chest.08-2123. Epub 2009 Mar 24.


Clinical decisions. Care of an unresponsive patient with a poor prognosis--polling results.

Kritek PA, Slutsky AS, Hudson LD.

N Engl J Med. 2009 Mar 5;360(10):e15. doi: 10.1056/NEJMclde0900810. No abstract available.


Clinical decisions. Care of an unresponsive patient with a poor prognosis.

Slutsky AS, Hudson LD.

N Engl J Med. 2009 Jan 29;360(5):527-31. doi: 10.1056/NEJMclde0808330. No abstract available.


Implementation and impact of a translational research training program in pulmonary and critical care medicine.

Schnapp LM, Vaught M, Park DR, Rubenfeld G, Goodman RB, Hudson LD.

Chest. 2009 Mar;135(3):688-694. doi: 10.1378/chest.08-1449. Epub 2008 Nov 18.


Identification of dynamically regulated microRNA and mRNA networks in developing oligodendrocytes.

Lau P, Verrier JD, Nielsen JA, Johnson KR, Notterpek L, Hudson LD.

J Neurosci. 2008 Nov 5;28(45):11720-30. doi: 10.1523/JNEUROSCI.1932-08.2008.


The effect of an intensive care unit staffing model on tidal volume in patients with acute lung injury.

Cooke CR, Watkins TR, Kahn JM, Treggiari MM, Caldwell E, Hudson LD, Rubenfeld GD.

Crit Care. 2008;12(6):R134. doi: 10.1186/cc7105. Epub 2008 Nov 3.


Intensive care unit-acquired neuromyopathy and corticosteroids in survivors of persistent ARDS.

Hough CL, Steinberg KP, Taylor Thompson B, Rubenfeld GD, Hudson LD.

Intensive Care Med. 2009 Jan;35(1):63-8. doi: 10.1007/s00134-008-1304-4. Epub 2008 Oct 23.


Predictors of hospital mortality in a population-based cohort of patients with acute lung injury.

Cooke CR, Kahn JM, Caldwell E, Okamoto VN, Heckbert SR, Hudson LD, Rubenfeld GD.

Crit Care Med. 2008 May;36(5):1412-20. doi: 10.1097/CCM.0b013e318170a375.


Steroid treatment for persistent ARDS: a word of caution.

Thompson BT, Ancukiewicz M, Hudson LD, Steinberg KP, Bernard GR.

Crit Care. 2007;11(6):425. No abstract available.


Effect of intensive care unit organizational model and structure on outcomes in patients with acute lung injury.

Treggiari MM, Martin DP, Yanez ND, Caldwell E, Hudson LD, Rubenfeld GD.

Am J Respir Crit Care Med. 2007 Oct 1;176(7):685-90. Epub 2007 Jun 7.


The association between body mass index and clinical outcomes in acute lung injury.

Morris AE, Stapleton RD, Rubenfeld GD, Hudson LD, Caldwell E, Steinberg KP.

Chest. 2007 Feb;131(2):342-8.


Hemodynamic monitoring in shock and implications for management. International Consensus Conference, Paris, France, 27-28 April 2006.

Antonelli M, Levy M, Andrews PJ, Chastre J, Hudson LD, Manthous C, Meduri GU, Moreno RP, Putensen C, Stewart T, Torres A.

Intensive Care Med. 2007 Apr;33(4):575-90.


Therapy for late-phase acute respiratory distress syndrome.

Hudson LD, Hough CL.

Clin Chest Med. 2006 Dec;27(4):671-7; abstract ix-x. Review.


Identification of a novel oligodendrocyte cell adhesion protein using gene expression profiling.

Nielsen JA, Maric D, Lau P, Barker JL, Hudson LD.

J Neurosci. 2006 Sep 27;26(39):9881-91.


PEEP or no PEEP--lung recruitment may be the solution.

Slutsky AS, Hudson LD.

N Engl J Med. 2006 Apr 27;354(17):1839-41. No abstract available.


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