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Items: 49

1.

Ganoderma Lucidum induces oxidative DNA damage and enhances the effect of 5-Fluorouracil in colorectal cancer in vitro and in vivo.

Opattova A, Horak J, Vodenkova S, Kostovcikova K, Cumova A, Macinga P, Galanova N, Rejhova A, Vodickova L, Kozics K, Turnovcova K, Hucl T, Sliva D, Vodicka P.

Mutat Res. 2019 Sep;845:403065. doi: 10.1016/j.mrgentox.2019.06.001. Epub 2019 Jun 3.

PMID:
31561886
2.

Functional evaluation of variants of unknown significance in the BRCA2 gene identified in genetic testing.

Heczkova M, Machackova E, Macinga P, Gallmeier E, Cahova M, Spicak J, Jirsa M, Foretova L, Hucl T.

Cancer Biol Ther. 2019;20(5):633-641. doi: 10.1080/15384047.2018.1550566. Epub 2019 Jan 13.

PMID:
30638113
3.

Role of endosonography prior to endoscopic treatment of esophageal cancer.

Hucl T.

Minerva Chir. 2018 Aug;73(4):410-416. doi: 10.23736/S0026-4733.18.07809-4. Epub 2018 Jun 29. Review.

4.

Endoscopic management of acute necrotizing pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) evidence-based multidisciplinary guidelines.

Arvanitakis M, Dumonceau JM, Albert J, Badaoui A, Bali MA, Barthet M, Besselink M, Deviere J, Oliveira Ferreira A, Gyökeres T, Hritz I, Hucl T, Milashka M, Papanikolaou IS, Poley JW, Seewald S, Vanbiervliet G, van Lienden K, van Santvoort H, Voermans R, Delhaye M, van Hooft J.

Endoscopy. 2018 May;50(5):524-546. doi: 10.1055/a-0588-5365. Epub 2018 Apr 9.

5.

Simultaneous occurrence of autoimmune pancreatitis and pancreatic cancer in patients resected for focal pancreatic mass.

Macinga P, Pulkertova A, Bajer L, Maluskova J, Oliverius M, Smejkal M, Heczkova M, Spicak J, Hucl T.

World J Gastroenterol. 2017 Mar 28;23(12):2185-2193. doi: 10.3748/wjg.v23.i12.2185.

6.

Complications of percutaneous endoscopic gastrostomy.

Hucl T, Spicak J.

Best Pract Res Clin Gastroenterol. 2016 Oct;30(5):769-781. doi: 10.1016/j.bpg.2016.10.002. Epub 2016 Oct 8. Review.

PMID:
27931635
7.

Complications in gastrointestinal endoscopy.

Hucl T, Dinis-Ribeiro M, Gralnek IM, Reddy N.

Best Pract Res Clin Gastroenterol. 2016 Oct;30(5):665-666. doi: 10.1016/j.bpg.2016.10.012. Epub 2016 Nov 4. No abstract available.

PMID:
27931627
8.

European Society of Gastrointestinal Endoscopy - Establishing the key unanswered research questions within gastrointestinal endoscopy.

Rees CJ, Ngu WS, Regula J, Bisschops R, Saftoiu A, Dekker E, Gralnek I, Ciocirlan M, Dinis-Ribeiro M, Jover R, Meisner S, Spada C, Hassan C, Valori R, Hucl T, Le Moine O, Domagk D, Kaminski MF, Bretthauer M, Rutter MD, Aabakken L, Ponchon T, Fockens P, Siersema PD.

Endoscopy. 2016 Oct;48(10):884-891. Epub 2016 Aug 2.

PMID:
27485483
9.

Comparison of Inflammatory Response to Transgastric and Transcolonic NOTES.

Hucl T, Benes M, Kocik M, Splichalova A, Maluskova J, Krak M, Lanska V, Heczkova M, Kieslichova E, Oliverius M, Spicak J.

Gastroenterol Res Pract. 2016;2016:7320275. doi: 10.1155/2016/7320275. Epub 2016 Jun 14.

10.

The European Society of Gastrointestinal Endoscopy Quality Improvement Initiative: developing performance measures.

Rutter MD, Senore C, Bisschops R, Domagk D, Valori R, Kaminski MF, Spada C, Bretthauer M, Bennett C, Bellisario C, Minozzi S, Hassan C, Rees C, Dinis-Ribeiro M, Hucl T, Ponchon T, Aabakken L, Fockens P.

United European Gastroenterol J. 2016 Feb;4(1):30-41. doi: 10.1177/2050640615624631. Epub 2015 Dec 17.

11.

Hyperthermia adds to trabectedin effectiveness and thermal enhancement is associated with BRCA2 degradation and impairment of DNA homologous recombination repair.

Harnicek D, Kampmann E, Lauber K, Hennel R, Cardoso Martins AS, Guo Y, Belka C, Mörtl S, Gallmeier E, Kanaar R, Mansmann U, Hucl T, Lindner LH, Hiddemann W, Issels RD.

Int J Cancer. 2016 Jul 15;139(2):467-79. doi: 10.1002/ijc.30070. Epub 2016 Mar 25.

12.

[Malignant biliary obstruction].

Hucl T.

Cas Lek Cesk. 2016;155(1):30-7. Review. Czech.

PMID:
26898789
13.

Removal of foreign bodies in the upper gastrointestinal tract in adults: European Society of Gastrointestinal Endoscopy (ESGE) Clinical Guideline.

Birk M, Bauerfeind P, Deprez PH, Häfner M, Hartmann D, Hassan C, Hucl T, Lesur G, Aabakken L, Meining A.

Endoscopy. 2016 May;48(5):489-96. doi: 10.1055/s-0042-100456. Epub 2016 Feb 10.

14.

Inactivation of BRCA2 in human cancer cells identifies a subset of tumors with enhanced sensitivity towards death receptor-mediated apoptosis.

De Toni EN, Ziesch A, Rizzani A, Török HP, Hocke S, Lü S, Wang SC, Hucl T, Göke B, Bruns C, Gallmeier E.

Oncotarget. 2016 Feb 23;7(8):9477-90. doi: 10.18632/oncotarget.7053.

15.

Prevalence and risk factors of steatosis after liver transplantation and patient outcomes.

Hejlova I, Honsova E, Sticova E, Lanska V, Hucl T, Spicak J, Jirsa M, Trunecka P.

Liver Transpl. 2016 May;22(5):644-55. doi: 10.1002/lt.24393. Epub 2016 Apr 5.

16.

The European Society of Gastrointestinal Endoscopy Quality Improvement Initiative: developing performance measures.

Rutter MD, Senore C, Bisschops R, Domagk D, Valori R, Kaminski MF, Spada C, Bretthauer M, Bennett C, Bellisario C, Minozzi S, Hassan C, Rees C, Dinis-Ribeiro M, Hucl T, Ponchon T, Aabakken L, Fockens P.

Endoscopy. 2016 Jan;48(1):81-9. doi: 10.1055/s-0035-1569580. Epub 2015 Dec 11.

17.

Diagnosis and management of nonvariceal upper gastrointestinal hemorrhage: European Society of Gastrointestinal Endoscopy (ESGE) Guideline.

Gralnek IM, Dumonceau JM, Kuipers EJ, Lanas A, Sanders DS, Kurien M, Rotondano G, Hucl T, Dinis-Ribeiro M, Marmo R, Racz I, Arezzo A, Hoffmann RT, Lesur G, de Franchis R, Aabakken L, Veitch A, Radaelli F, Salgueiro P, Cardoso R, Maia L, Zullo A, Cipolletta L, Hassan C.

Endoscopy. 2015 Oct;47(10):a1-46. doi: 10.1055/s-0034-1393172. Epub 2015 Sep 29.

18.

Acute GI obstruction.

Hucl T.

Best Pract Res Clin Gastroenterol. 2013 Oct;27(5):691-707. doi: 10.1016/j.bpg.2013.09.001. Epub 2013 Sep 15. Review.

PMID:
24160928
19.

Feasibility and efficiency of a new 22G core needle: a prospective comparison study.

Hucl T, Wee E, Anuradha S, Gupta R, Ramchandani M, Rakesh K, Shrestha R, Reddy DN, Lakhtakia S.

Endoscopy. 2013 Oct;45(10):792-8. doi: 10.1055/s-0033-1344217. Epub 2013 Sep 25.

PMID:
24068588
20.

Epithelial markers of colorectal carcinogenesis in ulcerative colitis and primary sclerosing cholangitis.

Wohl P, Hucl T, Drastich P, Kamenar D, Spicak J, Honsova E, Sticova E, Lodererova A, Matous J, Hill M, Wohl P, Kucera M.

World J Gastroenterol. 2013;19(14):2234-41. doi: 10.3748/wjg.v19.i14.2234.

21.

NOTES in Europe: summary of the working group reports of the 2012 EURO-NOTES meeting.

Meining A, Spaun G, Fernández-Esparrach G, Arezzo A, Wilhelm D, Martinek J, Spicak J, Feussner H, Fuchs KH, Hucl T, Meisner S, Neuhaus H.

Endoscopy. 2013;45(3):214-7. doi: 10.1055/s-0032-1326205. Epub 2013 Feb 27. Review.

22.

[Evaluation of variants of unknown significance in the BRCA2 gene].

Heczková M, Macháčková E, Jirsa M, Spičák J, Foretová L, Hucl T.

Klin Onkol. 2012;25 Suppl:S87-95. Review. Czech.

PMID:
22920214
23.

Patient and physician perception of natural orifice transluminal endoscopic appendectomy.

Hucl T, Saglova A, Benes M, Kocik M, Oliverius M, Valenta Z, Spicak J.

World J Gastroenterol. 2012 Apr 21;18(15):1800-5. doi: 10.3748/wjg.v18.i15.1800.

24.

[A detailed study of colon polyps].

Spičák J, Beneš M, Hucl T, Stirand P, Drastich P, Wohl P, Kamenář D, Kliment M, Kundratová E, Urban O, Pintová J, Pícha J, Suchánek S, Zelízko V, Stefanová M, Rehoř M, Nosek V, Zavoral M.

Vnitr Lek. 2012 Jan;58(1):18-23. Czech.

PMID:
22448696
25.

Natural orifice transluminal endoscopic surgery.

Hucl T, Spicak J.

Endoscopy. 2011 Nov;43(11):1000-3. doi: 10.1055/s-0031-1291405. Epub 2011 Nov 4. Review. No abstract available.

PMID:
22057766
26.

Endoscopic variceal band ligation compared with propranolol for prophylaxis of first variceal bleeding.

Drastich P, Lata J, Petrtyl J, Bruha R, Prochazka V, Vanasek T, Zdenek P, Skibova J, Hucl T, Spicak J.

Ann Hepatol. 2011 Apr-Jun;10(2):142-9.

27.

DNA repair: exploiting the Fanconi anemia pathway as a potential therapeutic target.

Hucl T, Gallmeier E.

Physiol Res. 2011;60(3):453-65. Epub 2011 Mar 14. Review.

28.

A novel double-endoloop technique for natural orifice transluminal endoscopic surgery gastric access site closure.

Hucl T, Benes M, Kocik M, Krak M, Maluskova J, Kieslichova E, Oliverius M, Spicak J.

Gastrointest Endosc. 2010 Apr;71(4):806-11. doi: 10.1016/j.gie.2009.10.058. Epub 2010 Feb 18.

PMID:
20170912
29.

Angiotensin-converting enzyme insertion/deletion polymorphism in patients with acute and chronic pancreatitis.

Hucl T, Kylanpää ML, Künzli B, Witt H, Lempinen M, Schneider A, Kemppainen E, Löhr M, Haas SL, Friess H, Ockenga J, Rosendahl J, Schulz HU, Gress T, Singer MV, Pfützer RH.

Eur J Gastroenterol Hepatol. 2009 Sep;21(9):1032-5. doi: 10.1097/MEG.0b013e328326f586.

PMID:
19307975
30.

Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence.

Brody JR, Hucl T, Costantino CL, Eshleman JR, Gallmeier E, Zhu H, van der Heijden MS, Winter JM, Wikiewicz AK, Yeo CJ, Kern SE.

Cancer Res. 2009 Feb 1;69(3):984-91. doi: 10.1158/0008-5472.CAN-08-3610. Epub 2009 Jan 20.

31.

Low incidence of adenocarcinoma and high-grade intraepithelial neoplasia in patients with Barrett's esophagus: a prospective cohort study.

Martinek J, Benes M, Brandtl P, Hucl T, Vasicek M, Voska L, Lanska V, Nosek V, Spicak J.

Endoscopy. 2008 Sep;40(9):711-6. doi: 10.1055/s-2008-1077502. Epub 2008 Aug 12.

PMID:
18698534
32.

A syngeneic variance library for functional annotation of human variation: application to BRCA2.

Hucl T, Rago C, Gallmeier E, Brody JR, Gorospe M, Kern SE.

Cancer Res. 2008 Jul 1;68(13):5023-30. doi: 10.1158/0008-5472.CAN-07-6189.

33.

Non-erosive and erosive gastroesophageal reflux diseases: No difference with regard to reflux pattern and motility abnormalities.

Martínek J, Benes M, Hucl T, Drastich P, Stirand P, Spicák J.

Scand J Gastroenterol. 2008;43(7):794-800. doi: 10.1080/00365520801908928.

PMID:
18584517
34.

Pancreaticobiliary malunion and incomplete pancreas divisum: an unusual cause of common bile duct obstruction.

Petrasek J, Hucl T, Spicak J.

Adv Med Sci. 2008;53(1):6-10. doi: 10.2478/v10039-008-0002-3.

PMID:
18467273
35.

Evaluating the drug-target relationship between thymidylate synthase expression and tumor response to 5-fluorouracil. Is it time to move forward?

Showalter SL, Showalter TN, Witkiewicz A, Havens R, Kennedy EP, Hucl T, Kern SE, Yeo CJ, Brody JR.

Cancer Biol Ther. 2008 Jul;7(7):986-94. Epub 2008 Apr 21. Review.

36.

High cancer-specific expression of mesothelin (MSLN) is attributable to an upstream enhancer containing a transcription enhancer factor dependent MCAT motif.

Hucl T, Brody JR, Gallmeier E, Iacobuzio-Donahue CA, Farrance IK, Kern SE.

Cancer Res. 2007 Oct 1;67(19):9055-65.

37.

HFE genotypes in patients with chronic pancreatitis and pancreatic adenocarcinoma.

Hucl T, Kylanpää-Bäck ML, Witt H, Künzli B, Lempinen M, Schneider A, Kemppainen E, Löhr M, Friess H, Ockenga J, Rosendahl J, Schulz HU, Gress T, Singer MV, Pfützer RH.

Genet Med. 2007 Jul;9(7):479-83.

PMID:
17666895
38.

SPINK1 variants in young-onset pancreatic cancer.

Hucl T, Jesnowski R, Pfützer RH, Elsässer HP, Löhr M.

J Gastroenterol. 2007 Jul;42(7):599. Epub 2007 Jul 25. No abstract available.

PMID:
17653660
39.

Distinguishing rational from irrational applications of pharmacogenetic synergies from the bench to clinical trials.

Hucl T, Gallmeier E, Kern SE.

Cell Cycle. 2007 Jun 1;6(11):1336-41. Epub 2007 Jun 27. Review.

PMID:
17568192
40.

Gene-specific selection against experimental fanconi anemia gene inactivation in human cancer.

Gallmeier E, Hucl T, Calhoun ES, Cunningham SC, Bunz F, Brody JR, Kern SE.

Cancer Biol Ther. 2007 May;6(5):654-60. Epub 2007 Feb 7.

PMID:
17387268
41.

Pancreas divisum does not modify the natural course of chronic pancreatitis.

Spicak J, Poulova P, Plucnarova J, Rehor M, Filipova H, Hucl T.

J Gastroenterol. 2007 Feb;42(2):135-9. Epub 2007 Mar 12.

PMID:
17351802
42.

High-throughput screening identifies novel agents eliciting hypersensitivity in Fanconi pathway-deficient cancer cells.

Gallmeier E, Hucl T, Brody JR, Dezentje DA, Tahir K, Kasparkova J, Brabec V, Bachman KE, Kern SE.

Cancer Res. 2007 Mar 1;67(5):2169-77.

43.
44.

Identifying allelic loss and homozygous deletions in pancreatic cancer without matched normals using high-density single-nucleotide polymorphism arrays.

Calhoun ES, Hucl T, Gallmeier E, West KM, Arking DE, Maitra A, Iacobuzio-Donahue CA, Chakravarti A, Hruban RH, Kern SE.

Cancer Res. 2006 Aug 15;66(16):7920-8.

45.

A proposed clinical test for monitoring fluoropyrimidine therapy: detection and stability of thymidylate synthase ternary complexes.

Brody JR, Gallmeier E, Yoshimura K, Hucl T, Kulesza P, Canto MI, Hruban RH, Schulick RD, Kern SE.

Cancer Biol Ther. 2006 Aug;5(8):923-7. Epub 2006 Aug 2.

PMID:
16855390
46.

Targeted disruption of FANCC and FANCG in human cancer provides a preclinical model for specific therapeutic options.

Gallmeier E, Calhoun ES, Rago C, Brody JR, Cunningham SC, Hucl T, Gorospe M, Kohli M, Lengauer C, Kern SE.

Gastroenterology. 2006 Jun;130(7):2145-54.

PMID:
16762635
47.

Targeted deletion of MKK4 in cancer cells: a detrimental phenotype manifests as decreased experimental metastasis and suggests a counterweight to the evolution of tumor-suppressor loss.

Cunningham SC, Gallmeier E, Hucl T, Dezentje DA, Calhoun ES, Falco G, Abdelmohsen K, Gorospe M, Kern SE.

Cancer Res. 2006 Jun 1;66(11):5560-4.

48.

Theoretical proposal: allele dosage of MAP2K4/MKK4 could rationalize frequent 17p loss in diverse human cancers.

Cunningham SC, Gallmeier E, Hucl T, Dezentje DA, Abdelmohsen K, Gorospe M, Kern SE.

Cell Cycle. 2006 May;5(10):1090-3. Epub 2006 May 15.

PMID:
16721048
49.

Absence of nocturnal acid breakthrough in Helicobacter pylori-positive subjects treated with twice-daily omeprazole.

Martínek J, Pantoflícková D, Hucl T, Benes M, Dorta G, Lukás M, Spicák J.

Eur J Gastroenterol Hepatol. 2004 May;16(5):445-50.

PMID:
15097035

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