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Items: 17

1.

Nur77 serves as a molecular brake of the metabolic switch during T cell activation to restrict autoimmunity.

Liebmann M, Hucke S, Koch K, Eschborn M, Ghelman J, Chasan AI, Glander S, Schädlich M, Kuhlencord M, Daber NM, Eveslage M, Beyer M, Dietrich M, Albrecht P, Stoll M, Busch KB, Wiendl H, Roth J, Kuhlmann T, Klotz L.

Proc Natl Acad Sci U S A. 2018 Aug 21;115(34):E8017-E8026. doi: 10.1073/pnas.1721049115. Epub 2018 Aug 2.

2.

Liver X receptor activation promotes differentiation of regulatory T cells.

Herold M, Breuer J, Hucke S, Knolle P, Schwab N, Wiendl H, Klotz L.

PLoS One. 2017 Sep 19;12(9):e0184985. doi: 10.1371/journal.pone.0184985. eCollection 2017.

3.

Activation of FXR pathway does not alter glial cell function.

Albrecht S, Fleck AK, Kirchberg I, Hucke S, Liebmann M, Klotz L, Kuhlmann T.

J Neuroinflammation. 2017 Mar 28;14(1):66. doi: 10.1186/s12974-017-0833-6.

4.

Targeting Different Monocyte/Macrophage Subsets Has No Impact on Outcome in Experimental Stroke.

Schmidt A, Strecker JK, Hucke S, Bruckmann NM, Herold M, Mack M, Diederich K, Schäbitz WR, Wiendl H, Klotz L, Minnerup J.

Stroke. 2017 Apr;48(4):1061-1069. doi: 10.1161/STROKEAHA.116.015577. Epub 2017 Mar 14.

PMID:
28292872
5.

B7-H1 shapes T-cell-mediated brain endothelial cell dysfunction and regional encephalitogenicity in spontaneous CNS autoimmunity.

Klotz L, Kuzmanov I, Hucke S, Gross CC, Posevitz V, Dreykluft A, Schulte-Mecklenbeck A, Janoschka C, Lindner M, Herold M, Schwab N, Ludwig-Portugall I, Kurts C, Meuth SG, Kuhlmann T, Wiendl H.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6182-E6191. Epub 2016 Sep 26.

6.

The farnesoid-X-receptor in myeloid cells controls CNS autoimmunity in an IL-10-dependent fashion.

Hucke S, Herold M, Liebmann M, Freise N, Lindner M, Fleck AK, Zenker S, Thiebes S, Fernandez-Orth J, Buck D, Luessi F, Meuth SG, Zipp F, Hemmer B, Engel DR, Roth J, Kuhlmann T, Wiendl H, Klotz L.

Acta Neuropathol. 2016 Sep;132(3):413-31. doi: 10.1007/s00401-016-1593-6. Epub 2016 Jul 6.

PMID:
27383204
7.

Sodium chloride promotes pro-inflammatory macrophage polarization thereby aggravating CNS autoimmunity.

Hucke S, Eschborn M, Liebmann M, Herold M, Freise N, Engbers A, Ehling P, Meuth SG, Roth J, Kuhlmann T, Wiendl H, Klotz L.

J Autoimmun. 2016 Feb;67:90-101. doi: 10.1016/j.jaut.2015.11.001. Epub 2015 Nov 14.

PMID:
26584738
8.

Implications of dietary salt intake for multiple sclerosis pathogenesis.

Hucke S, Wiendl H, Klotz L.

Mult Scler. 2016 Feb;22(2):133-9. doi: 10.1177/1352458515609431. Epub 2015 Oct 7. Review.

PMID:
26447064
9.

B7-H1 Selectively Controls TH17 Differentiation and Central Nervous System Autoimmunity via a Novel Non-PD-1-Mediated Pathway.

Herold M, Posevitz V, Chudyka D, Hucke S, Groß C, Kurth F, Leder C, Loser K, Kurts C, Knolle P, Klotz L, Wiendl H.

J Immunol. 2015 Oct 15;195(8):3584-95. doi: 10.4049/jimmunol.1402746. Epub 2015 Sep 16.

10.

Non-steroidal anti-inflammatory drug indometacin enhances endogenous remyelination.

Preisner A, Albrecht S, Cui QL, Hucke S, Ghelman J, Hartmann C, Taketo MM, Antel J, Klotz L, Kuhlmann T.

Acta Neuropathol. 2015 Aug;130(2):247-61. doi: 10.1007/s00401-015-1426-z. Epub 2015 May 6.

PMID:
25943886
11.

Fingolimod treatment promotes regulatory phenotype and function of B cells.

Grützke B, Hucke S, Gross CC, Herold MV, Posevitz-Fejfar A, Wildemann BT, Kieseier BC, Dehmel T, Wiendl H, Klotz L.

Ann Clin Transl Neurol. 2015 Feb;2(2):119-30. doi: 10.1002/acn3.155. Epub 2015 Jan 16.

12.

Salt-dependent chemotaxis of macrophages.

Müller S, Quast T, Schröder A, Hucke S, Klotz L, Jantsch J, Gerzer R, Hemmersbach R, Kolanus W.

PLoS One. 2013 Sep 16;8(9):e73439. doi: 10.1371/journal.pone.0073439. eCollection 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/1907a0e9-290a-4221-a3fa-9147cb48a6f3. PLoS One. 2014;9(3):e92756.

13.

Puma, but not noxa is essential for oligodendroglial cell death.

Hagemeier K, Lürbke A, Hucke S, Albrecht S, Preisner A, Klassen E, Hoffmann E, Cui QL, Antel J J, Brück W, Klotz L, Kuhlmann T.

Glia. 2013 Oct;61(10):1712-23. doi: 10.1002/glia.22552. Epub 2013 Aug 6.

PMID:
23922240
14.

Licensing of myeloid cells promotes central nervous system autoimmunity and is controlled by peroxisome proliferator-activated receptor γ.

Hucke S, Floßdorf J, Grützke B, Dunay IR, Frenzel K, Jungverdorben J, Linnartz B, Mack M, Peitz M, Brüstle O, Kurts C, Klockgether T, Neumann H, Prinz M, Wiendl H, Knolle P, Klotz L.

Brain. 2012 May;135(Pt 5):1586-605. doi: 10.1093/brain/aws058. Epub 2012 Mar 24.

PMID:
22447120
15.

The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity.

Klotz L, Burgdorf S, Dani I, Saijo K, Flossdorf J, Hucke S, Alferink J, Nowak N, Beyer M, Mayer G, Langhans B, Klockgether T, Waisman A, Eberl G, Schultze J, Famulok M, Kolanus W, Glass C, Kurts C, Knolle PA.

J Exp Med. 2009 Sep 28;206(10):2079-89. doi: 10.1084/jem.20082771. Epub 2009 Sep 8. Erratum in: J Exp Med. 2009 Dec 21;206(13):3159. Novak, Natalija [corrected to Nowak, Nina].

16.

Increased antigen cross-presentation but impaired cross-priming after activation of peroxisome proliferator-activated receptor gamma is mediated by up-regulation of B7H1.

Klotz L, Hucke S, Thimm D, Classen S, Gaarz A, Schultze J, Edenhofer F, Kurts C, Klockgether T, Limmer A, Knolle P, Burgdorf S.

J Immunol. 2009 Jul 1;183(1):129-36. doi: 10.4049/jimmunol.0804260. Epub 2009 Jun 17.

17.

Treatment of postoperative reactive hypoglycemia by a reversed intestinal segment.

Fink WJ, Hucke ST, Gray TW, Thompson BW, Read RC.

Am J Surg. 1976 Jan;131(1):19-22.

PMID:
1247149

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