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Neonatal end-of-life decision-making almost 20 years after the EURONIC study: A French survey.

Boize P, Borrhomee S, Michel P, Betremieux P, Hubert P, Moriette G.

Arch Pediatr. 2019 Jul 25. pii: S0929-693X(19)30110-1. doi: 10.1016/j.arcped.2019.06.007. [Epub ahead of print]


Comparing the qualitative performances of handheld NIR and Raman spectrophotometers for the detection of falsified pharmaceutical products.

Ciza PH, Sacre PY, Waffo C, Coïc L, Avohou H, Mbinze JK, Ngono R, Marini RD, Hubert P, Ziemons E.

Talanta. 2019 Sep 1;202:469-478. doi: 10.1016/j.talanta.2019.04.049. Epub 2019 May 1.


Associations between Weight Loss, Food Likes, Dietary Behaviors, and Chemosensory Function in Bariatric Surgery: A Case-Control Analysis in Women.

Hubert PA, Papasavas P, Stone A, Swede H, Huedo-Medina TB, Tishler D, Duffy VB.

Nutrients. 2019 Apr 9;11(4). pii: E804. doi: 10.3390/nu11040804.


Comparison of hyperspectral imaging techniques for the elucidation of falsified medicines composition.

Coic L, Sacré PY, Dispas A, Sakira AK, Fillet M, Marini RD, Hubert P, Ziemons E.

Talanta. 2019 Jun 1;198:457-463. doi: 10.1016/j.talanta.2019.02.032. Epub 2019 Feb 8.


Analytical quality by design: Development and control strategy for a LC method to evaluate the cannabinoids content in cannabis olive oil extracts.

Deidda R, Avohou HT, Baronti R, Davolio PL, Pasquini B, Del Bubba M, Hubert C, Hubert P, Orlandini S, Furlanetto S.

J Pharm Biomed Anal. 2019 Mar 20;166:326-335. doi: 10.1016/j.jpba.2019.01.032. Epub 2019 Jan 21.


A Comparison of Online Versus Offline Gambling Harm in Portuguese Pathological Gamblers: An Empirical Study.

Hubert P, Griffiths MD.

Int J Ment Health Addict. 2018;16(5):1219-1237. doi: 10.1007/s11469-017-9846-8. Epub 2017 Nov 29.


First inter-laboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities.

Dispas A, Marini R, Desfontaine V, Veuthey JL, Kotoni D, Losacco LG, Clarke A, Muscat Galea C, Mangelings D, Jocher BM, Regalado EL, Plachká K, Nováková L, Wuyts B, François I, Gray M, Aubin AJ, Tarafder A, Cazes M, Desvignes C, Villemet L, Sarrut M, Raimbault A, Lemasson E, Lesellier E, West C, Leek T, Wong M, Dai L, Zhang K, Grand-Guillaume Perrenoud A, Brunelli C, Hennig P, Bertin S, Mauge F, Da Costa N, Farrell WP, Hill M, Desphande N, Grangrade M, Sadaphule S, Yadav R, Rane S, Shringare S, Iguiniz M, Heinisch S, Lefevre J, Corbel E, Roques N, Heyden YV, Guillarme D, Hubert P.

J Pharm Biomed Anal. 2018 Nov 30;161:414-424. doi: 10.1016/j.jpba.2018.08.042. Epub 2018 Aug 23.


Risk-based approach for method development in pharmaceutical quality control context: A critical review.

Deidda R, Orlandini S, Hubert P, Hubert C.

J Pharm Biomed Anal. 2018 Nov 30;161:110-121. doi: 10.1016/j.jpba.2018.07.050. Epub 2018 Jul 30. Review.


Raman chemical imaging, a new tool in kidney stone structure analysis: Case-study and comparison to Fourier Transform Infrared spectroscopy.

Castiglione V, Sacré PY, Cavalier E, Hubert P, Gadisseur R, Ziemons E.

PLoS One. 2018 Aug 3;13(8):e0201460. doi: 10.1371/journal.pone.0201460. eCollection 2018.


Exploring the microbiome of the "star" freshwater diatom Asterionella formosa in a laboratory context.

Kojadinovic-Sirinelli M, Villain A, Puppo C, Fon Sing S, Prioretti L, Hubert P, Grégori G, Zhang Y, Sassi JF, Claverie JM, Blanc G, Gontero B.

Environ Microbiol. 2018 Oct;20(10):3601-3615. doi: 10.1111/1462-2920.14337. Epub 2018 Oct 10.


Towards a spray-coating method for the detection of low-dose compounds in pharmaceutical tablets using surface-enhanced Raman chemical imaging (SER-CI).

Cailletaud J, Bleye C, Dumont E, Sacré PY, Gut Y, Bultel L, Ginot YM, Hubert P, Ziemons E.

Talanta. 2018 Oct 1;188:584-592. doi: 10.1016/j.talanta.2018.06.037. Epub 2018 Jun 12.


Immunity drives TET1 regulation in cancer through NF-κB.

Collignon E, Canale A, Al Wardi C, Bizet M, Calonne E, Dedeurwaerder S, Garaud S, Naveaux C, Barham W, Wilson A, Bouchat S, Hubert P, Van Lint C, Yull F, Sotiriou C, Willard-Gallo K, Noel A, Fuks F.

Sci Adv. 2018 Jun 20;4(6):eaap7309. doi: 10.1126/sciadv.aap7309. eCollection 2018 Jun.


Implementation of a generic SFC-MS method for the quality control of potentially counterfeited medicinal cannabis with synthetic cannabinoids.

Jambo H, Dispas A, Avohou HT, André S, Hubert C, Lebrun P, Ziemons É, Hubert P.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Aug 15;1092:332-342. doi: 10.1016/j.jchromb.2018.05.049. Epub 2018 Jun 5.


Development of a SERS strategy to overcome the nanoparticle stabilisation effect in serum-containing samples: Application to the quantification of dopamine in the culture medium of PC-12 cells.

Dumont E, De Bleye C, Cailletaud J, Sacré PY, Van Lerberghe PB, Rogister B, Rance GA, Aylott JW, Hubert P, Ziemons E.

Talanta. 2018 Aug 15;186:8-16. doi: 10.1016/j.talanta.2018.04.038. Epub 2018 Apr 10.


A dualistic model of primary anal canal adenocarcinoma with distinct cellular origins, etiologies, inflammatory microenvironments and mutational signatures: implications for personalised medicine.

Herfs M, Roncarati P, Koopmansch B, Peulen O, Bruyere D, Lebeau A, Hendrick E, Hubert P, Poncin A, Penny W, Piazzon N, Monnien F, Guenat D, Mougin C, Prétet JL, Vuitton L, Segers K, Lambert F, Bours V, de Leval L, Valmary-Degano S, Quick CM, Crum CP, Delvenne P.

Br J Cancer. 2018 May;118(10):1302-1312. doi: 10.1038/s41416-018-0049-2. Epub 2018 Apr 27.


Compromise in uncertainty estimation by modelling and validation approaches for an HPLC-UV method for measurement of biochemical indicators of vitamins A and E.

Djellouli O, Rozet E, Dahmani B, Hubert P.

Analyst. 2018 Mar 12;143(6):1492-1501. doi: 10.1039/c7an01804e.


"NOTA-PRGD2 and NODAGA-PRGD2 : Bioconjugation, characterization, radiolabelling, and design space".

Salvé M, Avohou HT, Monbaliu JM, Lebrun P, Lemaire C, Damblon C, de Tullio P, Hubert P, Hustinx R, Luxen A.

J Labelled Comp Radiopharm. 2018 May 30;61(6):487-500. doi: 10.1002/jlcr.3613. Epub 2018 Apr 25.


Comparing methods suitable for monitoring marine mammals in low visibility conditions during seismic surveys.

Verfuss UK, Gillespie D, Gordon J, Marques TA, Miller B, Plunkett R, Theriault JA, Tollit DJ, Zitterbart DP, Hubert P, Thomas L.

Mar Pollut Bull. 2018 Jan;126:1-18. doi: 10.1016/j.marpolbul.2017.10.034. Epub 2017 Nov 7. Review.


Postdiarrheal hemolytic and uremic syndrome with severe multiorgan involvement and associated early risk factors.

Oualha M, Pierrepont S, Krug P, Gitiaux C, Hubert P, Lesage F, Salomon R.

Arch Pediatr. 2018 Feb;25(2):118-125. doi: 10.1016/j.arcped.2017.12.005. Epub 2018 Feb 1.


Early Noninvasive Ventilation and Nonroutine Transfusion for Acute Chest Syndrome in Sickle Cell Disease in Children: A Descriptive Study.

Heilbronner C, Merckx A, Brousse V, Allali S, Hubert P, de Montalembert M, Lesage F.

Pediatr Crit Care Med. 2018 May;19(5):e235-e241. doi: 10.1097/PCC.0000000000001468.


Search for Neutrinoless Quadruple-β Decay of ^{150}Nd with the NEMO-3 Detector.

Arnold R, Augier C, Barabash AS, Basharina-Freshville A, Blondel S, Blot S, Bongrand M, Boursette D, Brudanin V, Busto J, Caffrey AJ, Calvez S, Cascella M, Cerna C, Cesar JP, Chapon A, Chauveau E, Chopra A, Dawson L, Duchesneau D, Durand D, Egorov V, Eurin G, Evans JJ, Fajt L, Filosofov D, Flack R, Garrido X, Gómez H, Guillon B, Guzowski P, Hodák R, Huber A, Hubert P, Hugon C, Jullian S, Klimenko A, Kochetov O, Konovalov SI, Kovalenko V, Lalanne D, Lang K, Lemière Y, Le Noblet T, Liptak Z, Liu XR, Loaiza P, Lutter G, Macko M, Macolino C, Mamedov F, Marquet C, Mauger F, Morgan B, Mott J, Nemchenok I, Nomachi M, Nova F, Nowacki F, Ohsumi H, Patrick C, Pahlka RB, Perrot F, Piquemal F, Povinec P, Přidal P, Ramachers YA, Remoto A, Reyss JL, Riddle CL, Rukhadze E, Saakyan R, Salazar R, Sarazin X, Shitov Y, Simard L, Šimkovic F, Smetana A, Smolek K, Smolnikov A, Söldner-Rembold S, Soulé B, Štefánik D, Štekl I, Suhonen J, Sutton CS, Szklarz G, Thomas J, Timkin V, Torre S, Tretyak VI, Tretyak VI, Umatov VI, Vanushin I, Vilela C, Vorobel V, Waters D, Xie F, Žukauskas A; NEMO-3 Collaboration.

Phys Rev Lett. 2017 Jul 28;119(4):041801. doi: 10.1103/PhysRevLett.119.041801. Epub 2017 Jul 24.


Safety and tolerance of cidofovir as a 2% gel for local application in high-grade cervical intraepithelial neoplasia: A phase 1 investigation.

Bossens M, Jost M, Van Pachterbeke C, De Maertelaer V, Simon P, Frankenne F, Hubert P, Evrard B, Snoeck R.

Int J Clin Pharmacol Ther. 2018 Mar;56(3):134-141. doi: 10.5414/CP203126.


Supercritical fluid chromatography: a promising alternative to current bioanalytical techniques.

Dispas A, Jambo H, André S, Tyteca E, Hubert P.

Bioanalysis. 2018 Jan;10(2):107-124. doi: 10.4155/bio-2017-0211. Epub 2017 Dec 13. Review.


Is supercritical fluid chromatography hyphenated to mass spectrometry suitable for the quality control of vitamin D3 oily formulations?

Andri B, Dispas A, Klinkenberg R, Streel B, Marini RD, Ziémons E, Hubert P.

J Chromatogr A. 2017 Sep 15;1515:209-217. doi: 10.1016/j.chroma.2017.07.057. Epub 2017 Jul 27.


Development of an analytical method for crystalline content determination in amorphous solid dispersions produced by hot-melt extrusion using transmission Raman spectroscopy: A feasibility study.

Netchacovitch L, Dumont E, Cailletaud J, Thiry J, De Bleye C, Sacré PY, Boiret M, Evrard B, Hubert P, Ziemons E.

Int J Pharm. 2017 Sep 15;530(1-2):249-255. doi: 10.1016/j.ijpharm.2017.07.052. Epub 2017 Jul 23.


Global regression model for moisture content determination using near-infrared spectroscopy.

Clavaud M, Roggo Y, Dégardin K, Sacré PY, Hubert P, Ziemons E.

Eur J Pharm Biopharm. 2017 Oct;119:343-352. doi: 10.1016/j.ejpb.2017.07.007. Epub 2017 Jul 17.


Critical review of surface-enhanced Raman spectroscopy applications in the pharmaceutical field.

Cailletaud J, De Bleye C, Dumont E, Sacré PY, Netchacovitch L, Gut Y, Boiret M, Ginot YM, Hubert P, Ziemons E.

J Pharm Biomed Anal. 2018 Jan 5;147:458-472. doi: 10.1016/j.jpba.2017.06.056. Epub 2017 Jun 27. Review.


Detection of Poor Quality Artemisinin-based Combination Therapy (ACT) Medicines Marketed in Benin Using Simple and Advanced Analytical Techniques.

Yemoa A, Habyalimana V, Mbinze JK, Crickboom V, Muhigirwa B, Ngoya A, Sacre PY, Gbaguidi F, Quetin-Leclercq J, Hubert P, Marini RD.

Curr Drug Saf. 2017;12(3):178-186. doi: 10.2174/1574886312666170616092457.


Global approach for the validation of an in-line Raman spectroscopic method to determine the API content in real-time during a hot-melt extrusion process.

Netchacovitch L, Thiry J, De Bleye C, Dumont E, Cailletaud J, Sacré PY, Evrard B, Hubert P, Ziemons E.

Talanta. 2017 Aug 15;171:45-52. doi: 10.1016/j.talanta.2017.04.060. Epub 2017 Apr 26.


Promoting Vaginal Distribution of E7 and MCL-1 siRNA-Silencing Nanoparticles for Cervical Cancer Treatment.

Lechanteur A, Furst T, Evrard B, Delvenne P, Piel G, Hubert P.

Mol Pharm. 2017 May 1;14(5):1706-1717. doi: 10.1021/acs.molpharmaceut.6b01154. Epub 2017 Apr 7.


Application of design space optimization strategy to the development of LC methods for simultaneous analysis of 18 antiretroviral medicines and 4 major excipients used in various pharmaceutical formulations.

Habyalimana V, Mbinze JK, Yemoa AL, Waffo C, Diallo T, Tshilombo NK, Ntokamunda JK, Lebrun P, Hubert P, Marini RD.

J Pharm Biomed Anal. 2017 May 30;139:8-21. doi: 10.1016/j.jpba.2017.02.040. Epub 2017 Feb 24.


Optimization and validation of a fast supercritical fluid chromatography method for the quantitative determination of vitamin D3 and its related impurities.

Andri B, Lebrun P, Dispas A, Klinkenberg R, Streel B, Ziemons E, Marini RD, Hubert P.

J Chromatogr A. 2017 Mar 31;1491:171-181. doi: 10.1016/j.chroma.2017.01.090. Epub 2017 Feb 7.


Combination of partial least squares regression and design of experiments to model the retention of pharmaceutical compounds in supercritical fluid chromatography.

Andri B, Dispas A, Marini RD, Hubert P, Sassiat P, Al Bakain R, Thiébaut D, Vial J.

J Chromatogr A. 2017 Mar 31;1491:182-194. doi: 10.1016/j.chroma.2017.02.030. Epub 2017 Feb 16.


Aronia berry polyphenol consumption reduces plasma total and low-density lipoprotein cholesterol in former smokers without lowering biomarkers of inflammation and oxidative stress: a randomized controlled trial.

Xie L, Vance T, Kim B, Lee SG, Caceres C, Wang Y, Hubert PA, Lee JY, Chun OK, Bolling BW.

Nutr Res. 2017 Jan;37:67-77. doi: 10.1016/j.nutres.2016.12.007. Epub 2016 Dec 10.


Is there a role for clowns in paediatric intensive care units?

Mortamet G, Roumeliotis N, Vinit F, Simonds C, Dupic L, Hubert P.

Arch Dis Child. 2017 Jul;102(7):672-675. doi: 10.1136/archdischild-2016-311583. Epub 2017 Feb 8. Review.


[End-of-life in specialized medical pediatrics department: A French national survey].

Ravanello A, Desguerre I, Frache S, Hubert P, Orbach D, Aubry R.

Arch Pediatr. 2017 Mar;24(3):231-240. doi: 10.1016/j.arcped.2017.01.001. Epub 2017 Jan 26. French.


Parental perceptions of clown care in paediatric intensive care units.

Mortamet G, Merckx A, Roumeliotis N, Simonds C, Renolleau S, Hubert P.

J Paediatr Child Health. 2017 May;53(5):485-487. doi: 10.1111/jpc.13448. Epub 2017 Jan 10.


Proteomic signatures reveal a dualistic and clinically relevant classification of anal canal carcinoma.

Herfs M, Longuespée R, Quick CM, Roncarati P, Suarez-Carmona M, Hubert P, Lebeau A, Bruyere D, Mazzucchelli G, Smargiasso N, Baiwir D, Lai K, Dunn A, Obregon F, Yang EJ, Pauw E, Crum CP, Delvenne P.

J Pathol. 2017 Mar;241(4):522-533. doi: 10.1002/path.4858. Epub 2017 Jan 27.


Quantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography.

Dispas A, Desfontaine V, Andri B, Lebrun P, Kotoni D, Clarke A, Guillarme D, Hubert P.

J Pharm Biomed Anal. 2017 Feb 5;134:170-180. doi: 10.1016/j.jpba.2016.11.039. Epub 2016 Nov 27.


Continuous production of itraconazole-based solid dispersions by hot melt extrusion: Preformulation, optimization and design space determination.

Thiry J, Lebrun P, Vinassa C, Adam M, Netchacovitch L, Ziemons E, Hubert P, Krier F, Evrard B.

Int J Pharm. 2016 Dec 30;515(1-2):114-124. doi: 10.1016/j.ijpharm.2016.10.003. Epub 2016 Oct 5.


Validation of Analytical Methods for Plasma Total Antioxidant Capacity by Comparing with Urinary 8-Isoprostane Level.

Lee SG, Wang T, Vance TM, Hubert P, Kim DO, Koo SI, Chun OK.

J Microbiol Biotechnol. 2017 Feb 28;27(2):388-394. doi: 10.4014/jmb.1604.04053.


Valproic acid improves second-line regimen of small cell lung carcinoma in preclinical models.

Hubaux R, Vandermeers F, Cosse JP, Crisanti C, Kapoor V, Albelda SM, Mascaux C, Delvenne P, Hubert P, Willems L.

ERJ Open Res. 2015 Oct 19;1(2). pii: 00028-2015. eCollection 2015 Oct.


Moisture content determination in an antibody-drug conjugate freeze-dried medicine by near-infrared spectroscopy: A case study for release testing.

Clavaud M, Roggo Y, Dégardin K, Sacré PY, Hubert P, Ziemons E.

J Pharm Biomed Anal. 2016 Nov 30;131:380-390. doi: 10.1016/j.jpba.2016.09.014. Epub 2016 Sep 14.


Effective antitumor therapy based on a novel antibody-drug conjugate targeting the Tn carbohydrate antigen.

Sedlik C, Heitzmann A, Viel S, Ait Sarkouh R, Batisse C, Schmidt F, De La Rochere P, Amzallag N, Osinaga E, Oppezzo P, Pritsch O, Sastre-Garau X, Hubert P, Amigorena S, Piaggio E.

Oncoimmunology. 2016 Apr 22;5(7):e1171434. doi: 10.1080/2162402X.2016.1171434. eCollection 2016 Jul.


PEGylation of lipoplexes: The right balance between cytotoxicity and siRNA effectiveness.

Lechanteur A, Furst T, Evrard B, Delvenne P, Hubert P, Piel G.

Eur J Pharm Sci. 2016 Oct 10;93:493-503. doi: 10.1016/j.ejps.2016.08.058. Epub 2016 Sep 1.


Monitoring of anatabine release by methyl jasmonate elicited BY-2 cells using surface-enhanced Raman scattering.

De Bleye C, Dumont E, Dispas A, Hubert C, Sacré PY, Netchacovitch L, De Muyt B, Kevers C, Dommes J, Hubert P, Ziemons E.

Talanta. 2016 Nov 1;160:754-760. doi: 10.1016/j.talanta.2016.08.027. Epub 2016 Aug 6.


Description and Contribution of Brain Magnetic Resonance Imaging in Nontraumatic Critically Ill Children.

Mortamet G, Kossorotoff M, Baptiste A, Boddaert N, Castelle M, Hubert P, Lesage F, Renolleau S, Oualha M.

J Child Neurol. 2016 Dec;31(14):1584-1590. Epub 2016 Sep 2.


Inhibition of PlexA1-mediated brain tumor growth and tumor-associated angiogenesis using a transmembrane domain targeting peptide.

Jacob L, Sawma P, Garnier N, Meyer LA, Fritz J, Hussenet T, Spenlé C, Goetz J, Vermot J, Fernandez A, Baumlin N, Aci-Sèche S, Orend G, Roussel G, Crémel G, Genest M, Hubert P, Bagnard D.

Oncotarget. 2016 Sep 6;7(36):57851-57865. doi: 10.18632/oncotarget.11072.


Fingerprinting and validation of a LC-DAD method for the analysis of biflavanones in Garcinia kola-based antimalarial improved traditional medicines.

Tshibangu PT, Kapepula PM, Kapinga MJK, Lupona HK, Ngombe NK, Kalenda DT, Jansen O, Wauters JN, Tits M, Angenot L, Rozet E, Hubert P, Marini RD, Frédérich M.

J Pharm Biomed Anal. 2016 Sep 5;128:382-390. doi: 10.1016/j.jpba.2016.04.042. Epub 2016 Jun 9.


Children with Down syndrome: Clinical course and mortality-associated factors in a French medical paediatric intensive care unit.

Joffre C, Lesage F, Bustarret O, Hubert P, Oualha M.

J Paediatr Child Health. 2016 Jun;52(6):595-9. doi: 10.1111/jpc.13214.


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