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Pancreatitis cytosorbents (CytoSorb) inflammatory cytokine removal: A Prospective Study (PACIFIC).

Huber W, Algül H, Lahmer T, Mayr U, Lehmann M, Schmid RM, Faltlhauser A.

Medicine (Baltimore). 2019 Jan;98(4):e13044. doi: 10.1097/MD.0000000000013044.


Gain of CTCF-Anchored Chromatin Loops Marks the Exit from Naive Pluripotency.

Pękowska A, Klaus B, Xiang W, Severino J, Daigle N, Klein FA, Oleś M, Casellas R, Ellenberg J, Steinmetz LM, Bertone P, Huber W.

Cell Syst. 2018 Nov 28;7(5):482-495.e10. doi: 10.1016/j.cels.2018.09.003. Epub 2018 Nov 7.


Vitamin D Deficiency Is Highly Prevalent in Critically Ill Patients and a Risk Factor for Mortality: A Prospective Observational Study Comparing Noncirrhotic Patients and Patients With Cirrhosis.

Mayr U, Fahrenkrog-Petersen L, Batres-Baires G, Rasch S, Herner A, Schmid RM, Huber W, Lahmer T.

J Intensive Care Med. 2018 Oct 1:885066618803844. doi: 10.1177/0885066618803844. [Epub ahead of print]


Validation of RIFLE, AKIN, and a modified AKIN definition ("backward classification") of acute kidney injury in a general ICU: Analysis of a 1-year period.

Huber W, Schneider J, Lahmer T, Küchle C, Jungwirth B, Schmid RM, Schmid S.

Medicine (Baltimore). 2018 Sep;97(38):e12465. doi: 10.1097/MD.0000000000012465.


Vedolizumab use after failure of TNF-α antagonists in children and adolescents with inflammatory bowel disease.

Schneider AM, Weghuber D, Hetzer B, Entenmann A, Müller T, Zimmermann G, Schütz S, Huber WD, Pichler J.

BMC Gastroenterol. 2018 Sep 15;18(1):140. doi: 10.1186/s12876-018-0868-x.


Randomised controlled trial comparing preoperative carbohydrate loading with standard fasting in paediatric anaesthesia.

Tudor-Drobjewski BA, Marhofer P, Kimberger O, Huber WD, Roth G, Triffterer L.

Br J Anaesth. 2018 Sep;121(3):656-661. doi: 10.1016/j.bja.2018.04.040. Epub 2018 Jun 8.


Drug-based perturbation screen uncovers synergistic drug combinations in Burkitt lymphoma.

Tomska K, Kurilov R, Lee KS, Hüllein J, Lukas M, Sellner L, Walther T, Wagner L, Oleś M, Brors B, Huber W, Zenz T.

Sci Rep. 2018 Aug 13;8(1):12046. doi: 10.1038/s41598-018-30509-3.


Comparison of cardiac function index derived from femoral and jugular indicator injection for transpulmonary thermodilution with the PiCCO-device: A prospective observational study.

Herner A, Heilmaier M, Mayr U, Schmid RM, Huber W.

PLoS One. 2018 Jul 31;13(7):e0200740. doi: 10.1371/journal.pone.0200740. eCollection 2018.


Gallic acid, a common dietary phenolic protects against high fat diet induced DNA damage.

Setayesh T, Nersesyan A, Mišík M, Noorizadeh R, Haslinger E, Javaheri T, Lang E, Grusch M, Huber W, Haslberger A, Knasmüller S.

Eur J Nutr. 2018 Jul 23. doi: 10.1007/s00394-018-1782-2. [Epub ahead of print]


Increased risk of candidemia in patients with necrotising pancreatitis infected with candida species.

Rasch S, Mayr U, Phillip V, Schmid RM, Huber W, Algül H, Lahmer T.

Pancreatology. 2018 Sep;18(6):630-634. doi: 10.1016/j.pan.2018.07.005. Epub 2018 Jul 14.


Discordant anti-müllerian hormone (AMH) and follicle stimulating hormone (FSH) among women undergoing in vitro fertilization (IVF): which one is the better predictor for live birth?

Wang S, Zhang Y, Mensah V, Huber WJ 3rd, Huang YT, Alvero R.

J Ovarian Res. 2018 Jul 16;11(1):60. doi: 10.1186/s13048-018-0430-z.


Large-volume paracentesis effects plasma disappearance rate of indo-cyanine green in critically ill patients with decompensated liver cirrhosis and intraabdominal hypertension.

Mayr U, Fahrenkrog-Petersen L, Batres-Baires G, Herner A, Rasch S, Schmid RM, Huber W, Lahmer T.

Ann Intensive Care. 2018 Jul 6;8(1):78. doi: 10.1186/s13613-018-0422-6.


Mandatory criteria for the application of variability-based parameters of fluid responsiveness: a prospective study in different groups of ICU patients.

Huber W, Mayr U, Umgelter A, Franzen M, Reindl W, Schmid RM, Eckel F.

J Zhejiang Univ Sci B. 2018 Jul;19(7):515-524. doi: 10.1631/jzus.B1700243.


Mean arterial pressure targeted fluid resuscitation may lead to fluid overload: A bleeding-resuscitation animal experiment.

Öveges N, László I, Tánczos K, Németh M, Lebák G, Tudor-Drobjewski BA, Érces D, Kaszaki J, Rudas L, Huber W, Molnár Z.

PLoS One. 2018 Jun 28;13(6):e0196188. doi: 10.1371/journal.pone.0196188. eCollection 2018.


Multi-Omics Factor Analysis-a framework for unsupervised integration of multi-omics data sets.

Argelaguet R, Velten B, Arnol D, Dietrich S, Zenz T, Marioni JC, Buettner F, Huber W, Stegle O.

Mol Syst Biol. 2018 Jun 20;14(6):e8124. doi: 10.15252/msb.20178124.


[Management of Clostridium difficile infections at German intensive care units - results from a survey among intensivists].

Bruensing J, Buendgens L, Jochum C, Herbers U, Canbay A, Braun G, Trautwein C, Huber W, Koch A, Tacke F.

Z Gastroenterol. 2018 Jun;56(6):551-560. doi: 10.1055/s-0044-102103. Epub 2018 Jun 11. German.


Quantitative computed tomography in comparison with transpulmonary thermodilution for the estimation of pulmonary fluid status: a clinical study in critically ill patients.

Saugel B, Wildgruber M, Staudt A, Dieckmeyer M, Holzapfel K, Kaissis G, Kirov MY, Kuzkov VV, Schmid RM, Huber W.

J Clin Monit Comput. 2019 Feb;33(1):5-12. doi: 10.1007/s10877-018-0144-1. Epub 2018 Apr 21.


Accuracy and precision of ScvO2 measured with the CeVOX-device: A prospective study in patients with a wide variation of ScvO2-values.

Herner A, Haller B, Mayr U, Rasch S, Offman L, Schmid R, Huber W.

PLoS One. 2018 Apr 17;13(4):e0192073. doi: 10.1371/journal.pone.0192073. eCollection 2018.


TRRAP is essential for regulating the accumulation of mutant and wild-type p53 in lymphoma.

Jethwa A, Słabicki M, Hüllein J, Jentzsch M, Dalal V, Rabe S, Wagner L, Walther T, Klapper W; MMML Network Project, Bohnenberger H, Rettel M, Lu J, Smits AH, Stein F, Savitski MM, Huber W, Aylon Y, Oren M, Zenz T.

Blood. 2018 Jun 21;131(25):2789-2802. doi: 10.1182/blood-2017-09-806679. Epub 2018 Apr 13.


Correction to: Relationship Between Abdominal Symptoms and Fructose Ingestion in Children with Chronic Abdominal Pain.

Hammer V, Hammer K, Memaran N, Huber WD, Hammer K, Hammer J.

Dig Dis Sci. 2018 Jun;63(6):1670. doi: 10.1007/s10620-018-5046-z.


Impact of large volume paracentesis on respiratory parameters including transpulmonary pressure and on transpulmonary thermodilution derived hemodynamics: A prospective study.

Mayr U, Karsten E, Lahmer T, Rasch S, Thies P, Henschel B, Fischer G, Schmid RM, Huber W.

PLoS One. 2018 Mar 14;13(3):e0193654. doi: 10.1371/journal.pone.0193654. eCollection 2018.


Relationship Between Abdominal Symptoms and Fructose Ingestion in Children with Chronic Abdominal Pain.

Hammer V, Hammer K, Memaran N, Huber WD, Hammer K, Hammer J.

Dig Dis Sci. 2018 May;63(5):1270-1279. doi: 10.1007/s10620-018-4997-4. Epub 2018 Mar 7. Erratum in: Dig Dis Sci. 2018 Apr 2;:.


Proteome-wide identification of ubiquitin interactions using UbIA-MS.

Zhang X, Smits AH, van Tilburg GB, Ovaa H, Huber W, Vermeulen M.

Nat Protoc. 2018 Mar;13(3):530-550. doi: 10.1038/nprot.2017.147. Epub 2018 Feb 15.


Mesenchyme-derived factors enhance preneoplastic growth by non-genotoxic carcinogens in rat liver.

Nejabat M, Riegler T, Reitinger T, Subosits S, Römer M, Eichner J, Bilban M, Zell A, Huber WW, Schulte-Hermann R, Grasl-Kraupp B.

Arch Toxicol. 2018 Feb;92(2):953-966. doi: 10.1007/s00204-017-2080-0. Epub 2017 Dec 21.


Drug-perturbation-based stratification of blood cancer.

Dietrich S, Oleś M, Lu J, Sellner L, Anders S, Velten B, Wu B, Hüllein J, da Silva Liberio M, Walther T, Wagner L, Rabe S, Ghidelli-Disse S, Bantscheff M, Oleś AK, Słabicki M, Mock A, Oakes CC, Wang S, Oppermann S, Lukas M, Kim V, Sill M, Benner A, Jauch A, Sutton LA, Young E, Rosenquist R, Liu X, Jethwa A, Lee KS, Lewis J, Putzker K, Lutz C, Rossi D, Mokhir A, Oellerich T, Zirlik K, Herling M, Nguyen-Khac F, Plass C, Andersson E, Mustjoki S, von Kalle C, Ho AD, Hensel M, Dürig J, Ringshausen I, Zapatka M, Huber W, Zenz T.

J Clin Invest. 2018 Jan 2;128(1):427-445. doi: 10.1172/JCI93801. Epub 2017 Dec 11.


Use of HuH6 and other human-derived hepatoma lines for the detection of genotoxins: a new hope for laboratory animals?

Waldherr M, Mišík M, Ferk F, Tomc J, Žegura B, Filipič M, Mikulits W, Mai S, Haas O, Huber WW, Haslinger E, Knasmüller S.

Arch Toxicol. 2018 Feb;92(2):921-934. doi: 10.1007/s00204-017-2109-4. Epub 2017 Dec 7.


Alternative start and termination sites of transcription drive most transcript isoform differences across human tissues.

Reyes A, Huber W.

Nucleic Acids Res. 2018 Jan 25;46(2):582-592. doi: 10.1093/nar/gkx1165.


Expression Atlas: gene and protein expression across multiple studies and organisms.

Papatheodorou I, Fonseca NA, Keays M, Tang YA, Barrera E, Bazant W, Burke M, Füllgrabe A, Fuentes AM, George N, Huerta L, Koskinen S, Mohammed S, Geniza M, Preece J, Jaiswal P, Jarnuczak AF, Huber W, Stegle O, Vizcaino JA, Brazma A, Petryszak R.

Nucleic Acids Res. 2018 Jan 4;46(D1):D246-D251. doi: 10.1093/nar/gkx1158.


The novel language-systematic aphasia screening SAPS: screening-based therapy in combination with computerised home training.

Krzok F, Rieger V, Niemann K, Nobis-Bosch R, Radermacher I, Huber W, Willmes K, Abel S.

Int J Lang Commun Disord. 2018 Mar;53(2):308-323. doi: 10.1111/1460-6984.12350. Epub 2017 Nov 8.


Two independent modes of chromatin organization revealed by cohesin removal.

Schwarzer W, Abdennur N, Goloborodko A, Pekowska A, Fudenberg G, Loe-Mie Y, Fonseca NA, Huber W, H Haering C, Mirny L, Spitz F.

Nature. 2017 Nov 2;551(7678):51-56. doi: 10.1038/nature24281. Epub 2017 Sep 27.


Mandating Coverage for Fertility Preservation - A Step in the Right Direction.

Cardozo ER, Huber WJ, Stuckey AR, Alvero RJ.

N Engl J Med. 2017 Oct 26;377(17):1607-1609. doi: 10.1056/NEJMp1709585. No abstract available.


Comparison of pulmonary vascular permeability index PVPI and global ejection fraction GEF derived from jugular and femoral indicator injection using the PiCCO-2 device: A prospective observational study.

Huber W, Gruber A, Eckmann M, Elkmann F, Klein I, Lahmer T, Mayr U, Schellnegger R, Schneider J, Batres-Baires G, Fekecs L, Beitz A, Berbara H, Schmid R, Herner A.

PLoS One. 2017 Oct 17;12(10):e0178372. doi: 10.1371/journal.pone.0178372. eCollection 2017.


Upregulation of SPS100 gene expression by an antisense RNA via a switch of mRNA isoforms with different stabilities.

Bunina D, Štefl M, Huber F, Khmelinskii A, Meurer M, Barry JD, Kats I, Kirrmaier D, Huber W, Knop M.

Nucleic Acids Res. 2017 Nov 2;45(19):11144-11158. doi: 10.1093/nar/gkx737.


First description of spontaneous fungal peritonitis caused by Fusarium solani in a critically ill patient with liver cirrhosis.

Mayr U, Rasch S, Schmid RM, Huber W, Lahmer T.

New Microbes New Infect. 2017 Aug 16;20:16-17. doi: 10.1016/j.nmni.2017.08.003. eCollection 2017 Nov.


Research Techniques Made Simple: Bioinformatics for Genome-Scale Biology.

Foulkes AC, Watson DS, Griffiths CEM, Warren RB, Huber W, Barnes MR.

J Invest Dermatol. 2017 Sep;137(9):e163-e168. doi: 10.1016/j.jid.2017.07.095. Review.


Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling.

Andersson EI, Pützer S, Yadav B, Dufva O, Khan S, He L, Sellner L, Schrader A, Crispatzu G, Oleś M, Zhang H, Adnan-Awad S, Lagström S, Bellanger D, Mpindi JP, Eldfors S, Pemovska T, Pietarinen P, Lauhio A, Tomska K, Cuesta-Mateos C, Faber E, Koschmieder S, Brümmendorf TH, Kytölä S, Savolainen ER, Siitonen T, Ellonen P, Kallioniemi O, Wennerberg K, Ding W, Stern MH, Huber W, Anders S, Tang J, Aittokallio T, Zenz T, Herling M, Mustjoki S.

Leukemia. 2018 Mar;32(3):774-787. doi: 10.1038/leu.2017.252. Epub 2017 Aug 14.


Questionable Design to Validate the ProAQT/Pulsioflex Device.

Umgelter A, Schmid RM, Huber W.

Anesth Analg. 2017 Oct;125(4):1417-1420. doi: 10.1213/ANE.0000000000002333. No abstract available.


Evaluation of an ADVanced Organ Support (ADVOS) system in a two-hit porcine model of liver failure plus endotoxemia.

Al-Chalabi A, Matevossian E, von Thaden A, Schreiber C, Radermacher P, Huber W, Perez Ruiz de Garibay A, Kreymann B.

Intensive Care Med Exp. 2017 Dec;5(1):31. doi: 10.1186/s40635-017-0144-3. Epub 2017 Jul 4.


Advanced hemodynamic monitoring in intensive care medicine : A German web-based survey study.

Saugel B, Reese PC, Wagner JY, Buerke M, Huber W, Kluge S, Prondzinsky R.

Med Klin Intensivmed Notfmed. 2018 Apr;113(3):192-201. doi: 10.1007/s00063-017-0302-0. Epub 2017 May 4.


In-parallel connected intermittent hemodialysis through ECMO does not affect hemodynamic parameters derived from transpulmonary thermodilution.

Lahmer T, Mayr U, Rasch S, Batres Baires G, Schmid RM, Huber W.

Perfusion. 2017 Nov;32(8):702-705. doi: 10.1177/0267659117707816. Epub 2017 Apr 25.


[Acute Pancreatitis: What is new?]

Huber W, Phillip V, Schmid R, Schneider J.

Dtsch Med Wochenschr. 2017 Apr;142(7):525-529. doi: 10.1055/s-0042-100233. Epub 2017 Apr 7. German. No abstract available.


Usefulness of 1,3 Beta-D-Glucan Detection in non-HIV Immunocompromised Mechanical Ventilated Critically Ill Patients with ARDS and Suspected Pneumocystis jirovecii Pneumonia.

Lahmer T, da Costa CP, Held J, Rasch S, Ehmer U, Schmid RM, Huber W.

Mycopathologia. 2017 Aug;182(7-8):701-708. doi: 10.1007/s11046-017-0132-x. Epub 2017 Apr 4.


Human haematopoietic stem cell lineage commitment is a continuous process.

Velten L, Haas SF, Raffel S, Blaszkiewicz S, Islam S, Hennig BP, Hirche C, Lutz C, Buss EC, Nowak D, Boch T, Hofmann WK, Ho AD, Huber W, Trumpp A, Essers MA, Steinmetz LM.

Nat Cell Biol. 2017 Apr;19(4):271-281. doi: 10.1038/ncb3493. Epub 2017 Mar 20.


Intensive speech and language therapy in patients with chronic aphasia after stroke: a randomised, open-label, blinded-endpoint, controlled trial in a health-care setting.

Breitenstein C, Grewe T, Flöel A, Ziegler W, Springer L, Martus P, Huber W, Willmes K, Ringelstein EB, Haeusler KG, Abel S, Glindemann R, Domahs F, Regenbrecht F, Schlenck KJ, Thomas M, Obrig H, de Langen E, Rocker R, Wigbers F, Rühmkorf C, Hempen I, List J, Baumgaertner A; FCET2EC study group.

Lancet. 2017 Apr 15;389(10078):1528-1538. doi: 10.1016/S0140-6736(17)30067-3. Epub 2017 Mar 1. Erratum in: Lancet. 2017 Apr 15;389(10078):1518.


First clinical experience in 14 patients treated with ADVOS: a study on feasibility, safety and efficacy of a new type of albumin dialysis.

Huber W, Henschel B, Schmid R, Al-Chalabi A.

BMC Gastroenterol. 2017 Feb 16;17(1):32. doi: 10.1186/s12876-017-0569-x.


miR-16 and miR-125b are involved in barrier function dysregulation through the modulation of claudin-2 and cingulin expression in the jejunum in IBS with diarrhoea.

Martínez C, Rodiño-Janeiro BK, Lobo B, Stanifer ML, Klaus B, Granzow M, González-Castro AM, Salvo-Romero E, Alonso-Cotoner C, Pigrau M, Roeth R, Rappold G, Huber W, González-Silos R, Lorenzo J, de Torres I, Azpiroz F, Boulant S, Vicario M, Niesler B, Santos J.

Gut. 2017 Sep;66(9):1537-1538. doi: 10.1136/gutjnl-2016-311477. Epub 2017 Jan 12.


Xanthohumol Prevents DNA Damage by Dietary Carcinogens: Results of a Human Intervention Trial.

Pichler C, Ferk F, Al-Serori H, Huber W, Jäger W, Waldherr M, Mišík M, Kundi M, Nersesyan A, Herbacek I, Knasmueller S.

Cancer Prev Res (Phila). 2017 Feb;10(2):153-160. doi: 10.1158/1940-6207.CAPR-15-0378. Epub 2016 Dec 6.


Functional Outcomes and Quality of Life After Radical Prostatectomy Only Versus a Combination of Prostatectomy with Radiation and Hormonal Therapy.

Adam M, Tennstedt P, Lanwehr D, Tilki D, Steuber T, Beyer B, Thederan I, Heinzer H, Haese A, Salomon G, Budäus L, Michl U, Pehrke D, Stattin P, Bernard J, Klaus B, Pompe RS, Petersen C, Huland H, Graefen M, Schwarz R, Huber W, Loeb S, Schlomm T.

Eur Urol. 2017 Mar;71(3):330-336. doi: 10.1016/j.eururo.2016.11.015. Epub 2016 Nov 22.


The Shh Topological Domain Facilitates the Action of Remote Enhancers by Reducing the Effects of Genomic Distances.

Symmons O, Pan L, Remeseiro S, Aktas T, Klein F, Huber W, Spitz F.

Dev Cell. 2016 Dec 5;39(5):529-543. doi: 10.1016/j.devcel.2016.10.015. Epub 2016 Nov 17.


Severe hydrocarbon pneumonitis in African refugees after fuel ingestion.

Spinner CD, Seilmaier M, Al-Chalabi A, Schneider J, Huber W.

Lancet. 2016 Nov 12;388(10058):2350-2351. doi: 10.1016/S0140-6736(16)32130-4. No abstract available.


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