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Items: 1 to 50 of 177

1.

Effect of nursery feeding program on serum haptoglobin, growth performance, and carcass characteristics of pigs reared on commercial farms.

Reinhardt H, Shoveller AK, Farzan A, McBride B, Huber LA, de Lange CFM.

Can J Vet Res. 2019 Oct;83(4):255-260.

PMID:
31571724
2.

Photoprotection But Not N-Acetylcysteine Improves Intestinal Blood Flow and Oxidation Status in Parenterally Fed Piglets.

Huber LA, Lee T, LeDrew RL, Dodge ME, Brunton JA, Bertolo RF.

J Pediatr Gastroenterol Nutr. 2019 Sep 17. doi: 10.1097/MPG.0000000000002498. [Epub ahead of print]

PMID:
31568154
3.

LAMTOR/Ragulator regulates lipid metabolism in macrophages and foam cell differentiation.

Lamberti G, De Smet CH, Angelova M, Kremser L, Taub N, Herrmann C, Hess MW, Rainer J, Tancevski I, Schweigreiter R, Kofler R, Schmiedinger T, Vietor I, Trajanoski Z, Ejsing CS, Lindner HH, Huber LA, Stasyk T.

FEBS Lett. 2019 Aug 19. doi: 10.1002/1873-3468.13579. [Epub ahead of print]

PMID:
31423582
4.

The effects of a temporary lysine restriction in newly weaned pigs on growth performance and body composition1.

Totafurno AD, Huber LA, Mansilla WD, Wey D, Mandell IB, De Lange CFM.

J Anim Sci. 2019 Sep 3;97(9):3859-3870. doi: 10.1093/jas/skz196.

PMID:
31330536
5.

Biogenesis of lysosome-related organelles complex-1 (BORC) regulates late endosomal/lysosomal size through PIKfyve-dependent phosphatidylinositol-3,5-bisphosphate.

Yordanov TE, Hipolito VEB, Liebscher G, Vogel GF, Stasyk T, Herrmann C, Geley S, Teis D, Botelho RJ, Hess MW, Huber LA.

Traffic. 2019 Sep;20(9):674-696. doi: 10.1111/tra.12679.

6.

LAMTOR2 (p14) Controls B Cell Differentiation by Orchestrating Endosomal BCR Trafficking.

Łyszkiewicz M, Kotlarz D, Ziȩtara N, Brandes G, Diestelhorst J, Glage S, Hobeika E, Reth M, Huber LA, Krueger A, Klein C.

Front Immunol. 2019 Mar 18;10:497. doi: 10.3389/fimmu.2019.00497. eCollection 2019.

7.

Health Benefits of Supplementing Nursery Pig Diets with Microalgae or Fish Oil.

Lee AV, You L, Oh SY, Li Z, Code A, Zhu C, Fisher-Heffernan RE, Regnault TRH, De Lange CFM, Huber LA, Karrow NA.

Animals (Basel). 2019 Mar 5;9(3). pii: E80. doi: 10.3390/ani9030080.

8.

Effects of dietary leucine supplementation and immune system stimulation on plasma AA concentrations and tissue protein synthesis in starter pigs.

Rudar M, Huber LA, Zhu CL, de Lange CFM.

J Anim Sci. 2019 Feb 1;97(2):829-838. doi: 10.1093/jas/sky449.

PMID:
30476328
9.

β-1,3-glucan-lacking Aspergillus fumigatus mediates an efficient antifungal immune response by activating complement and dendritic cells.

Steger M, Bermejo-Jambrina M, Yordanov T, Wagener J, Brakhage AA, Pittl V, Huber LA, Haas H, Lass-Flörl C, Posch W, Wilflingseder D.

Virulence. 2018 Oct 29:1-13. doi: 10.1080/21505594.2018.1528843. [Epub ahead of print]

PMID:
30372658
10.

Loss of MYO5B Leads to Reductions in Na+ Absorption With Maintenance of CFTR-Dependent Cl- Secretion in Enterocytes.

Engevik AC, Kaji I, Engevik MA, Meyer AR, Weis VG, Goldstein A, Hess MW, Müller T, Koepsell H, Dudeja PK, Tyska M, Huber LA, Shub MD, Ameen N, Goldenring JR.

Gastroenterology. 2018 Dec;155(6):1883-1897.e10. doi: 10.1053/j.gastro.2018.08.025. Epub 2018 Aug 23.

PMID:
30144427
11.

Effect of reducing the ratio of omega-6-to-omega-3 fatty acids in diets of low protein quality on nursery pig growth performance and immune response.

Huber LA, Hooda S, Fisher-Heffernan RE, Karrow NA, de Lange CFM.

J Anim Sci. 2018 Sep 29;96(10):4348-4359. doi: 10.1093/jas/sky296.

12.

Combining high-pressure freezing with pre-embedding immunogold electron microscopy and tomography.

Hess MW, Vogel GF, Yordanov TE, Witting B, Gutleben K, Ebner HL, de Araujo MEG, Filipek PA, Huber LA.

Traffic. 2018 Aug;19(8):639-649. doi: 10.1111/tra.12575. Epub 2018 May 21.

13.

Complete Mechanism of Hemithioindigo Motor Rotation.

Wilcken R, Schildhauer M, Rott F, Huber LA, Guentner M, Thumser S, Hoffmann K, Oesterling S, de Vivie-Riedle R, Riedle E, Dube H.

J Am Chem Soc. 2018 Apr 18;140(15):5311-5318. doi: 10.1021/jacs.8b02349. Epub 2018 Apr 9.

PMID:
29578704
14.

Whole-body nitrogen utilization and tissue protein and casein synthesis in lactating primiparous sows fed low- and high-protein diets.

Huber LA, Rudar M, Trottier NL, Cant JP, de Lange CFM.

J Anim Sci. 2018 Jun 4;96(6):2380-2391. doi: 10.1093/jas/sky047.

15.

DIGE-Based Phosphoproteomic Analysis.

Stasyk T, Huber LA.

Methods Mol Biol. 2018;1664:79-86. doi: 10.1007/978-1-4939-7268-5_7.

PMID:
29019126
16.

LAMTOR/Ragulator is a negative regulator of Arl8b- and BORC-dependent late endosomal positioning.

Filipek PA, de Araujo MEG, Vogel GF, De Smet CH, Eberharter D, Rebsamen M, Rudashevskaya EL, Kremser L, Yordanov T, Tschaikner P, Fürnrohr BG, Lechner S, Dunzendorfer-Matt T, Scheffzek K, Bennett KL, Superti-Furga G, Lindner HH, Stasyk T, Huber LA.

J Cell Biol. 2017 Dec 4;216(12):4199-4215. doi: 10.1083/jcb.201703061. Epub 2017 Oct 9.

17.

Crystal structure of the human lysosomal mTORC1 scaffold complex and its impact on signaling.

de Araujo MEG, Naschberger A, Fürnrohr BG, Stasyk T, Dunzendorfer-Matt T, Lechner S, Welti S, Kremser L, Shivalingaiah G, Offterdinger M, Lindner HH, Huber LA, Scheffzek K.

Science. 2017 Oct 20;358(6361):377-381. doi: 10.1126/science.aao1583. Epub 2017 Sep 21.

PMID:
28935770
18.

Direct Observation of Hemithioindigo-Motor Unidirectionality.

Huber LA, Hoffmann K, Thumser S, Böcher N, Mayer P, Dube H.

Angew Chem Int Ed Engl. 2017 Nov 13;56(46):14536-14539. doi: 10.1002/anie.201708178. Epub 2017 Oct 12.

PMID:
28892243
19.

Disrupted apical exocytosis of cargo vesicles causes enteropathy in FHL5 patients with Munc18-2 mutations.

Vogel GF, van Rijn JM, Krainer IM, Janecke AR, Posovszky C, Cohen M, Searle C, Jantchou P, Escher JC, Patey N, Cutz E, Müller T, Middendorp S, Hess MW, Huber LA.

JCI Insight. 2017 Jul 20;2(14). pii: 94564. doi: 10.1172/jci.insight.94564. eCollection 2017 Jul 20.

20.

A novel but frequent variant in LPA KIV-2 is associated with a pronounced Lp(a) and cardiovascular risk reduction.

Coassin S, Erhart G, Weissensteiner H, Eca Guimarães de Araújo M, Lamina C, Schönherr S, Forer L, Haun M, Losso JL, Köttgen A, Schmidt K, Utermann G, Peters A, Gieger C, Strauch K, Finkenstedt A, Bale R, Zoller H, Paulweber B, Eckardt KU, Hüttenhofer A, Huber LA, Kronenberg F.

Eur Heart J. 2017 Jun 14;38(23):1823-1831. doi: 10.1093/eurheartj/ehx174.

21.

Abnormal Rab11-Rab8-vesicles cluster in enterocytes of patients with microvillus inclusion disease.

Vogel GF, Janecke AR, Krainer IM, Gutleben K, Witting B, Mitton SG, Mansour S, Ballauff A, Roland JT, Engevik AC, Cutz E, Müller T, Goldenring JR, Huber LA, Hess MW.

Traffic. 2017 Jul;18(7):453-464. doi: 10.1111/tra.12486. Epub 2017 May 17.

22.

Deficiency of the sphingosine-1-phosphate lyase SGPL1 is associated with congenital nephrotic syndrome and congenital adrenal calcifications.

Janecke AR, Xu R, Steichen-Gersdorf E, Waldegger S, Entenmann A, Giner T, Krainer I, Huber LA, Hess MW, Frishberg Y, Barash H, Tzur S, Schreyer-Shafir N, Sukenik-Halevy R, Zehavi T, Raas-Rothschild A, Mao C, Müller T.

Hum Mutat. 2017 Apr;38(4):365-372. doi: 10.1002/humu.23192. Epub 2017 Mar 6.

23.

New Mouse Models for Microvillus Inclusion Disease (MVID): Where Do the Inclusions Come From and Are They Cause or Consequence?

Huber LA.

Cell Mol Gastroenterol Hepatol. 2016 Jan 18;2(2):112-113. doi: 10.1016/j.jcmgh.2015.12.012. eCollection 2016 Mar. No abstract available.

24.

TIS7 induces transcriptional cascade of methylosome components required for muscle differentiation.

Lammirato A, Patsch K, Feiereisen F, Maly K, Nofziger C, Paulmichl M, Hackl H, Trajanoski Z, Valovka T, Huber LA, Vietor I.

BMC Biol. 2016 Oct 25;14(1):95.

25.

Asymmetric arginine dimethylation of RelA provides a repressive mark to modulate TNFα/NF-κB response.

Reintjes A, Fuchs JE, Kremser L, Lindner HH, Liedl KR, Huber LA, Valovka T.

Proc Natl Acad Sci U S A. 2016 Apr 19;113(16):4326-31. doi: 10.1073/pnas.1522372113. Epub 2016 Apr 5.

26.

Towards understanding microvillus inclusion disease.

Vogel GF, Hess MW, Pfaller K, Huber LA, Janecke AR, Müller T.

Mol Cell Pediatr. 2016 Dec;3(1):3. doi: 10.1186/s40348-016-0031-0. Epub 2016 Jan 29.

27.

Lysosomal signaling in control of degradation pathways.

Huber LA, Teis D.

Curr Opin Cell Biol. 2016 Apr;39:8-14. doi: 10.1016/j.ceb.2016.01.006. Epub 2016 Jan 28. Review.

28.

Purification of Early and Late Endosomes.

de Araújo ME, Lamberti G, Huber LA.

Cold Spring Harb Protoc. 2015 Dec 2;2015(12):pdb.top074443. doi: 10.1101/pdb.top074443.

PMID:
26631131
29.

Isolation of Macrophage Early and Late Endosomes by Latex Bead Internalization and Density Gradient Centrifugation.

Lamberti G, de Araújo ME, Huber LA.

Cold Spring Harb Protoc. 2015 Dec 2;2015(12):pdb.prot083451. doi: 10.1101/pdb.prot083451.

PMID:
26631120
30.

Topical Skin Cancer Therapy Using Doxorubicin-Loaded Cationic Lipid Nanoparticles and lontophoresis.

Huber LA, Pereira TA, Ramos DN, Rezende LC, Emery FS, Sobral LM, Leopoldino AM, Lopez RF.

J Biomed Nanotechnol. 2015 Nov;11(11):1975-88.

PMID:
26554156
31.

Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3.

Vogel GF, Klee KM, Janecke AR, Müller T, Hess MW, Huber LA.

J Cell Biol. 2015 Nov 9;211(3):587-604. doi: 10.1083/jcb.201506112.

32.

Isolation of Early and Late Endosomes by Density Gradient Centrifugation.

de Araújo ME, Lamberti G, Huber LA.

Cold Spring Harb Protoc. 2015 Nov 2;2015(11):1013-6. doi: 10.1101/pdb.prot083444.

PMID:
26527762
33.

Homogenization of Mammalian Cells.

de Araújo ME, Lamberti G, Huber LA.

Cold Spring Harb Protoc. 2015 Nov 2;2015(11):1009-12. doi: 10.1101/pdb.prot083436.

PMID:
26527761
34.

Spatio-Temporal Parameters of Endosomal Signaling in Cancer: Implications for New Treatment Options.

Stasyk T, Huber LA.

J Cell Biochem. 2016 Apr;117(4):836-43. doi: 10.1002/jcb.25418. Epub 2015 Nov 16. Review.

35.

An inducible mouse model for microvillus inclusion disease reveals a role for myosin Vb in apical and basolateral trafficking.

Schneeberger K, Vogel GF, Teunissen H, van Ommen DD, Begthel H, El Bouazzaoui L, van Vugt AH, Beekman JM, Klumperman J, Müller T, Janecke A, Gerner P, Huber LA, Hess MW, Clevers H, van Es JH, Nieuwenhuis EE, Middendorp S.

Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):12408-13. doi: 10.1073/pnas.1516672112. Epub 2015 Sep 21.

36.

Ultrastructural Morphometry Points to a New Role for LAMTOR2 in Regulating the Endo/Lysosomal System.

Vogel GF, Ebner HL, de Araujo ME, Schmiedinger T, Eiter O, Pircher H, Gutleben K, Witting B, Teis D, Huber LA, Hess MW.

Traffic. 2015 Jun;16(6):617-34. doi: 10.1111/tra.12271. Epub 2015 Apr 14.

37.

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.

Rebsamen M, Pochini L, Stasyk T, de Araújo ME, Galluccio M, Kandasamy RK, Snijder B, Fauster A, Rudashevskaya EL, Bruckner M, Scorzoni S, Filipek PA, Huber KV, Bigenzahn JW, Heinz LX, Kraft C, Bennett KL, Indiveri C, Huber LA, Superti-Furga G.

Nature. 2015 Mar 26;519(7544):477-81. doi: 10.1038/nature14107. Epub 2015 Jan 7.

38.

LAMTOR2 regulates dendritic cell homeostasis through FLT3-dependent mTOR signalling.

Scheffler JM, Sparber F, Tripp CH, Herrmann C, Humenberger A, Blitz J, Romani N, Stoitzner P, Huber LA.

Nat Commun. 2014 Oct 22;5:5138. doi: 10.1038/ncomms6138.

39.

Interleukin-like epithelial-to-mesenchymal transition inducer activity is controlled by proteolytic processing and plasminogen-urokinase plasminogen activator receptor system-regulated secretion during breast cancer progression.

Csiszar A, Kutay B, Wirth S, Schmidt U, Macho-Maschler S, Schreiber M, Alacakaptan M, Vogel GF, Aumayr K, Huber LA, Beug H.

Breast Cancer Res. 2014 Sep 9;16(5):433. doi: 10.1186/s13058-014-0433-7.

40.

The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells.

Sparber F, Tripp CH, Komenda K, Scheffler JM, Clausen BE, Huber LA, Romani N, Stoitzner P.

J Invest Dermatol. 2015 Jan;135(1):119-129. doi: 10.1038/jid.2014.324. Epub 2014 Jul 31.

41.

The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal adhesion dynamics during cell migration.

Schiefermeier N, Scheffler JM, de Araujo ME, Stasyk T, Yordanov T, Ebner HL, Offterdinger M, Munck S, Hess MW, Wickström SA, Lange A, Wunderlich W, Fässler R, Teis D, Huber LA.

J Cell Biol. 2014 May 26;205(4):525-40. doi: 10.1083/jcb.201310043. Epub 2014 May 19.

42.

LAMTOR2-mediated modulation of NGF/MAPK activation kinetics during differentiation of PC12 cells.

Thauerer B, Voegele P, Hermann-Kleiter N, Thuille N, de Araujo ME, Offterdinger M, Baier G, Huber LA, Baier-Bitterlich G.

PLoS One. 2014 Apr 21;9(4):e95863. doi: 10.1371/journal.pone.0095863. eCollection 2014.

43.

Loss of syntaxin 3 causes variant microvillus inclusion disease.

Wiegerinck CL, Janecke AR, Schneeberger K, Vogel GF, van Haaften-Visser DY, Escher JC, Adam R, Thöni CE, Pfaller K, Jordan AJ, Weis CA, Nijman IJ, Monroe GR, van Hasselt PM, Cutz E, Klumperman J, Clevers H, Nieuwenhuis EE, Houwen RH, van Haaften G, Hess MW, Huber LA, Stapelbroek JM, Müller T, Middendorp S.

Gastroenterology. 2014 Jul;147(1):65-68.e10. doi: 10.1053/j.gastro.2014.04.002. Epub 2014 Apr 12.

PMID:
24726755
44.

Screening for MAPK modulators using an in-cell western assay.

Schnaiter S, Fürst B, Neu J, Wáczek F, Orfi L, Kéri G, Huber LA, Wunderlich W.

Methods Mol Biol. 2014;1120:121-9. doi: 10.1007/978-1-62703-791-4_8.

PMID:
24470022
45.

Mild fixation and permeabilization protocol for preserving structures of endosomes, focal adhesions, and actin filaments during immunofluorescence analysis.

Scheffler JM, Schiefermeier N, Huber LA.

Methods Enzymol. 2014;535:93-102. doi: 10.1016/B978-0-12-397925-4.00006-7.

PMID:
24377919
46.

Microvillus inclusion disease: loss of Myosin vb disrupts intracellular traffic and cell polarity.

Thoeni CE, Vogel GF, Tancevski I, Geley S, Lechner S, Pfaller K, Hess MW, Müller T, Janecke AR, Avitzur Y, Muise A, Cutz E, Huber LA.

Traffic. 2014 Jan;15(1):22-42. doi: 10.1111/tra.12131. Epub 2013 Nov 19.

47.

The late endosomal adaptor molecule p14 (LAMTOR2) represents a novel regulator of Langerhans cell homeostasis.

Sparber F, Scheffler JM, Amberg N, Tripp CH, Heib V, Hermann M, Zahner SP, Clausen BE, Reizis B, Huber LA, Stoitzner P, Romani N.

Blood. 2014 Jan 9;123(2):217-27. doi: 10.1182/blood-2013-08-518555. Epub 2013 Oct 3.

48.

Stability of the endosomal scaffold protein LAMTOR3 depends on heterodimer assembly and proteasomal degradation.

de Araújo ME, Stasyk T, Taub N, Ebner HL, Fürst B, Filipek P, Weys SR, Hess MW, Lindner H, Kremser L, Huber LA.

J Biol Chem. 2013 Jun 21;288(25):18228-42. doi: 10.1074/jbc.M112.349480. Epub 2013 May 7.

49.

A new type of metal chelate affinity chromatography using trivalent lanthanide ions for phosphopeptide enrichment.

Mirza MR, Rainer M, Messner CB, Güzel Y, Schemeth D, Stasyk T, Choudhary MI, Huber LA, Rode BM, Bonn GK.

Analyst. 2013 May 21;138(10):2995-3004. doi: 10.1039/c3an36853j.

PMID:
23552617
50.

Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk.

De Araujo ME, Erhart G, Buck K, Müller-Holzner E, Hubalek M, Fiegl H, Campa D, Canzian F, Eilber U, Chang-Claude J, Coassin S, Haun M, Kedenko L, Paulweber B, Reitsamer R, Himmel I, Flesch-Janys D, Lamina C, Kronenberg F, Huber LA, Kloss-Brandstätter A.

PLoS One. 2013;8(1):e53768. doi: 10.1371/journal.pone.0053768. Epub 2013 Jan 16.

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