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Items: 1 to 50 of 84

1.

Local cortical circuit correlates of altered EEG in the mouse model of Fragile X syndrome.

Goswami S, Cavalier S, Sridhar V, Huber KM, Gibson JR.

Neurobiol Dis. 2019 Apr;124:563-572. doi: 10.1016/j.nbd.2019.01.002. Epub 2019 Jan 9.

PMID:
30639292
2.

Optimization of ribosome profiling using low-input brain tissue from fragile X syndrome model mice.

Liu B, Molinaro G, Shu H, Stackpole EE, Huber KM, Richter JD.

Nucleic Acids Res. 2019 Mar 18;47(5):e25. doi: 10.1093/nar/gky1292.

3.

Cabozantinib Exhibits Potent Antitumor Activity in Colorectal Cancer Patient-Derived Tumor Xenograft Models via Autophagy and Signaling Mechanisms.

Scott AJ, Arcaroli JJ, Bagby SM, Yahn R, Huber KM, Serkova NJ, Nguyen A, Kim J, Thorburn A, Vogel J, Quackenbush KS, Capasso A, Schreiber A, Blatchford P, Klauck PJ, Pitts TM, Eckhardt SG, Messersmith WA.

Mol Cancer Ther. 2018 Oct;17(10):2112-2122. doi: 10.1158/1535-7163.MCT-17-0131. Epub 2018 Jul 19.

PMID:
30026382
4.

Synaptic homeostasis: quality vs. quantity.

Huber KM.

Nat Neurosci. 2018 Jun;21(6):774-776. doi: 10.1038/s41593-018-0159-4. No abstract available.

PMID:
29760526
5.

The Impact of Perioperative Hormonal Therapy for Breast Cancer on Transverse Rectus Abdominis Myocutaneous Flap Abdominal Complications.

Huber KM, Clayman E, Kumar A, Smith P.

Ann Plast Surg. 2018 Jun;80(6S Suppl 6):S348-S351. doi: 10.1097/SAP.0000000000001323.

PMID:
29369111
6.

Improvement in Existing Chest Wall Irregularities During Breast Reconstruction.

Huber KM, Zimmerman A, Dayicioglu D.

Cancer Control. 2018 Jan-Mar;25(1):1073274817744461. doi: 10.1177/1073274817744461. Review.

7.

Palmitoylation and Membrane Binding of Arc/Arg3.1: A Potential Role in Synaptic Depression.

Barylko B, Wilkerson JR, Cavalier SH, Binns DD, James NG, Jameson DM, Huber KM, Albanesi JP.

Biochemistry. 2018 Feb 6;57(5):520-524. doi: 10.1021/acs.biochem.7b00959. Epub 2017 Dec 26.

PMID:
29264923
8.

Roles for Arc in metabotropic glutamate receptor-dependent LTD and synapse elimination: Implications in health and disease.

Wilkerson JR, Albanesi JP, Huber KM.

Semin Cell Dev Biol. 2018 May;77:51-62. doi: 10.1016/j.semcdb.2017.09.035. Epub 2017 Oct 14. Review.

9.

Distinct stages of synapse elimination are induced by burst firing of CA1 neurons and differentially require MEF2A/D.

Chang CW, Wilkerson JR, Hale CF, Gibson JR, Huber KM.

Elife. 2017 Sep 13;6. pii: e26278. doi: 10.7554/eLife.26278.

10.

Acamprosate in a mouse model of fragile X syndrome: modulation of spontaneous cortical activity, ERK1/2 activation, locomotor behavior, and anxiety.

Schaefer TL, Davenport MH, Grainger LM, Robinson CK, Earnheart AT, Stegman MS, Lang AL, Ashworth AA, Molinaro G, Huber KM, Erickson CA.

J Neurodev Disord. 2017 Jun 12;9:6. doi: 10.1186/s11689-017-9184-y. eCollection 2017.

11.

FMRP-dependent Mdm2 dephosphorylation is required for MEF2-induced synapse elimination.

Tsai NP, Wilkerson JR, Guo W, Huber KM.

Hum Mol Genet. 2017 Jan 15;26(2):293-304. doi: 10.1093/hmg/ddw386.

12.

Protocadherins and the Social Brain.

Tsai NP, Huber KM.

Biol Psychiatry. 2017 Feb 1;81(3):173-174. doi: 10.1016/j.biopsych.2016.10.025. No abstract available.

13.

APP Causes Hyperexcitability in Fragile X Mice.

Westmark CJ, Chuang SC, Hays SA, Filon MJ, Ray BC, Westmark PR, Gibson JR, Huber KM, Wong RK.

Front Mol Neurosci. 2016 Dec 15;9:147. doi: 10.3389/fnmol.2016.00147. eCollection 2016.

14.

Experience-Dependent and Differential Regulation of Local and Long-Range Excitatory Neocortical Circuits by Postsynaptic Mef2c.

Rajkovich KE, Loerwald KW, Hale CF, Hess CT, Gibson JR, Huber KM.

Neuron. 2017 Jan 4;93(1):48-56. doi: 10.1016/j.neuron.2016.11.022. Epub 2016 Dec 15.

15.

Nonoperative Treatment of a Tracheocutaneous Fistula in a Burn Patient.

Huber KM, Billington AR, Taylor LJ, Maynell KB, Wayne Cruse C.

J Burn Care Res. 2017 Jul/Aug;38(4):e772-e775. doi: 10.1097/BCR.0000000000000473.

PMID:
27893570
16.

MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.

Harrington AJ, Raissi A, Rajkovich K, Berto S, Kumar J, Molinaro G, Raduazzo J, Guo Y, Loerwald K, Konopka G, Huber KM, Cowan CW.

Elife. 2016 Oct 25;5. pii: e20059. doi: 10.7554/eLife.20059.

17.

Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice.

Ade KK, Wan Y, Hamann HC, O'Hare JK, Guo W, Quian A, Kumar S, Bhagat S, Rodriguiz RM, Wetsel WC, Conn PJ, Dzirasa K, Huber KM, Calakos N.

Biol Psychiatry. 2016 Oct 1;80(7):522-33. doi: 10.1016/j.biopsych.2016.04.023. Epub 2016 May 13.

18.

Selective Disruption of Metabotropic Glutamate Receptor 5-Homer Interactions Mimics Phenotypes of Fragile X Syndrome in Mice.

Guo W, Molinaro G, Collins KA, Hays SA, Paylor R, Worley PF, Szumlinski KK, Huber KM.

J Neurosci. 2016 Feb 17;36(7):2131-47. doi: 10.1523/JNEUROSCI.2921-15.2016.

19.

Outcomes of Breast Reconstruction After Mastectomy Using Tissue Expander and Implant Reconstruction.

Huber KM, Zemina KL, Tugertimur B, Killebrew SR, Wilson AR, DallaRosa JV, Prabhakaran S, Dayicioglu D.

Ann Plast Surg. 2016 Jun;76 Suppl 4:S316-9. doi: 10.1097/SAP.0000000000000675.

PMID:
26678106
20.

Elevated CaMKII╬▒ and Hyperphosphorylation of Homer Mediate Circuit Dysfunction in a Fragile X Syndrome Mouse Model.

Guo W, Ceolin L, Collins KA, Perroy J, Huber KM.

Cell Rep. 2015 Dec 15;13(10):2297-311. doi: 10.1016/j.celrep.2015.11.013. Epub 2015 Dec 6.

21.

Dysregulation of Mammalian Target of Rapamycin Signaling in Mouse Models of Autism.

Huber KM, Klann E, Costa-Mattioli M, Zukin RS.

J Neurosci. 2015 Oct 14;35(41):13836-42. doi: 10.1523/JNEUROSCI.2656-15.2015. Review.

22.

Autism-Associated Chromatin Regulator Brg1/SmarcA4 Is Required for Synapse Development and Myocyte Enhancer Factor 2-Mediated Synapse Remodeling.

Zhang Z, Cao M, Chang CW, Wang C, Shi X, Zhan X, Birnbaum SG, Bezprozvanny I, Huber KM, Wu JI.

Mol Cell Biol. 2015 Oct 12;36(1):70-83. doi: 10.1128/MCB.00534-15. Print 2016 Jan 1.

23.

Estrogen promotes the brain metastatic colonization of triple negative breast cancer cells via an astrocyte-mediated paracrine mechanism.

Sartorius CA, Hanna CT, Gril B, Cruz H, Serkova NJ, Huber KM, Kabos P, Schedin TB, Borges VF, Steeg PS, Cittelly DM.

Oncogene. 2016 Jun 2;35(22):2881-92. doi: 10.1038/onc.2015.353. Epub 2015 Sep 28.

24.

Severe pulmonary hypertension is associated with altered right ventricle metabolic substrate uptake.

Graham BB, Kumar R, Mickael C, Sanders L, Gebreab L, Huber KM, Perez M, Smith-Jones P, Serkova NJ, Tuder RM.

Am J Physiol Lung Cell Mol Physiol. 2015 Sep 1;309(5):L435-40. doi: 10.1152/ajplung.00169.2015. Epub 2015 Jun 26.

25.

IgM exacerbates glomerular disease progression in complement-induced glomerulopathy.

Panzer SE, Laskowski J, Renner B, Kulik L, Ljubanovic D, Huber KM, Zhong W, Pickering MC, Holers VM, Thurman JM.

Kidney Int. 2015 Sep;88(3):528-37. doi: 10.1038/ki.2015.120. Epub 2015 May 6.

26.

Increased expression of the PI3K enhancer PIKE mediates deficits in synaptic plasticity and behavior in fragile X syndrome.

Gross C, Chang CW, Kelly SM, Bhattacharya A, McBride SM, Danielson SW, Jiang MQ, Chan CB, Ye K, Gibson JR, Klann E, Jongens TA, Moberg KH, Huber KM, Bassell GJ.

Cell Rep. 2015 May 5;11(5):727-36. doi: 10.1016/j.celrep.2015.03.060. Epub 2015 Apr 23.

27.

Selective role of the catalytic PI3K subunit p110╬▓ in impaired higher order cognition in fragile X syndrome.

Gross C, Raj N, Molinaro G, Allen AG, Whyte AJ, Gibson JR, Huber KM, Gourley SL, Bassell GJ.

Cell Rep. 2015 May 5;11(5):681-8. doi: 10.1016/j.celrep.2015.03.065. Epub 2015 Apr 23.

28.

Enhancement of dynamin polymerization and GTPase activity by Arc/Arg3.1.

Byers CE, Barylko B, Ross JA, Southworth DR, James NG, Taylor CA 4th, Wang L, Collins KA, Estrada A, Waung M, Tassin TC, Huber KM, Jameson DM, Albanesi JP.

Biochim Biophys Acta. 2015 Jun;1850(6):1310-8. doi: 10.1016/j.bbagen.2015.03.002. Epub 2015 Mar 14.

30.

Postsynaptic mGluR5 promotes evoked AMPAR-mediated synaptic transmission onto neocortical layer 2/3 pyramidal neurons during development.

Loerwald KW, Patel AB, Huber KM, Gibson JR.

J Neurophysiol. 2015 Feb 1;113(3):786-95. doi: 10.1152/jn.00465.2014. Epub 2014 Nov 12.

31.

Activity-dependent FUS dysregulation disrupts synaptic homeostasis.

Sephton CF, Tang AA, Kulkarni A, West J, Brooks M, Stubblefield JJ, Liu Y, Zhang MQ, Green CB, Huber KM, Huang EJ, Herz J, Yu G.

Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):E4769-78. doi: 10.1073/pnas.1406162111. Epub 2014 Oct 16.

32.

Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo.

Kavitha CV, Jain AK, Agarwal C, Pierce A, Keating A, Huber KM, Serkova NJ, Wempe MF, Agarwal R, Deep G.

Mol Carcinog. 2015 Nov;54(11):1417-29. doi: 10.1002/mc.22220. Epub 2014 Sep 22.

33.

A role for dendritic mGluR5-mediated local translation of Arc/Arg3.1 in MEF2-dependent synapse elimination.

Wilkerson JR, Tsai NP, Maksimova MA, Wu H, Cabalo NP, Loerwald KW, Dictenberg JB, Gibson JR, Huber KM.

Cell Rep. 2014 Jun 12;7(5):1589-1600. doi: 10.1016/j.celrep.2014.04.035. Epub 2014 May 22.

34.

Fragile X mental retardation protein regulates synaptic and behavioral plasticity to repeated cocaine administration.

Smith LN, Jedynak JP, Fontenot MR, Hale CF, Dietz KC, Taniguchi M, Thomas FS, Zirlin BC, Birnbaum SG, Huber KM, Thomas MJ, Cowan CW.

Neuron. 2014 May 7;82(3):645-58. doi: 10.1016/j.neuron.2014.03.028.

35.

Postsynaptic FMRP promotes the pruning of cell-to-cell connections among pyramidal neurons in the L5A neocortical network.

Patel AB, Loerwald KW, Huber KM, Gibson JR.

J Neurosci. 2014 Feb 26;34(9):3413-8. doi: 10.1523/JNEUROSCI.2921-13.2014.

36.

Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism.

D'Antoni S, Spatuzza M, Bonaccorso CM, Musumeci SA, Ciranna L, Nicoletti F, Huber KM, Catania MV.

Neurosci Biobehav Rev. 2014 Oct;46 Pt 2:228-41. doi: 10.1016/j.neubiorev.2014.02.003. Epub 2014 Feb 15. Review.

37.

Experience-induced Arc/Arg3.1 primes CA1 pyramidal neurons for metabotropic glutamate receptor-dependent long-term synaptic depression.

Jakkamsetti V, Tsai NP, Gross C, Molinaro G, Collins KA, Nicoletti F, Wang KH, Osten P, Bassell GJ, Gibson JR, Huber KM.

Neuron. 2013 Oct 2;80(1):72-9. doi: 10.1016/j.neuron.2013.07.020. Epub 2013 Oct 2.

38.

Small molecules enable neurogenin 2 to efficiently convert human fibroblasts into cholinergic neurons.

Liu ML, Zang T, Zou Y, Chang JC, Gibson JR, Huber KM, Zhang CL.

Nat Commun. 2013;4:2183. doi: 10.1038/ncomms3183.

39.

Incidence of sentinel lymph node involvement in a modern, large series of desmoplastic melanoma.

Egger ME, Huber KM, Dunki-Jacobs EM, Quillo AR, Scoggins CR, Martin RC 2nd, Stromberg AJ, McMasters KM, Callender GG.

J Am Coll Surg. 2013 Jul;217(1):37-44; discussion 44-5. doi: 10.1016/j.jamcollsurg.2013.05.006.

PMID:
23791271
40.

Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation.

Derry MM, Raina K, Balaiya V, Jain AK, Shrotriya S, Huber KM, Serkova NJ, Agarwal R, Agarwal C.

Cancer Prev Res (Phila). 2013 Jul;6(7):625-33. doi: 10.1158/1940-6207.CAPR-13-0053. Epub 2013 May 2.

41.

Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity.

Zang T, Maksimova MA, Cowan CW, Bassel-Duby R, Olson EN, Huber KM.

Mol Cell Neurosci. 2013 Sep;56:39-49. doi: 10.1016/j.mcn.2013.03.002. Epub 2013 Mar 17.

42.

A target cell-specific role for presynaptic Fmr1 in regulating glutamate release onto neocortical fast-spiking inhibitory neurons.

Patel AB, Hays SA, Bureau I, Huber KM, Gibson JR.

J Neurosci. 2013 Feb 6;33(6):2593-604. doi: 10.1523/JNEUROSCI.2447-12.2013.

43.

Ruptured hypogastric artery aneurysms: a contemporary review.

Morris ME, Huber KM, Maijub JG.

Vasc Endovascular Surg. 2013 Apr;47(3):239-44. doi: 10.1177/1538574413475887. Epub 2013 Feb 5. Review.

PMID:
23386670
44.

Multiple autism-linked genes mediate synapse elimination via proteasomal degradation of a synaptic scaffold PSD-95.

Tsai NP, Wilkerson JR, Guo W, Maksimova MA, DeMartino GN, Cowan CW, Huber KM.

Cell. 2012 Dec 21;151(7):1581-94. doi: 10.1016/j.cell.2012.11.040.

45.

Inositol hexaphosphate inhibits tumor growth, vascularity, and metabolism in TRAMP mice: a multiparametric magnetic resonance study.

Raina K, Ravichandran K, Rajamanickam S, Huber KM, Serkova NJ, Agarwal R.

Cancer Prev Res (Phila). 2013 Jan;6(1):40-50. doi: 10.1158/1940-6207.CAPR-12-0387. Epub 2012 Dec 4.

46.

Implications of anomalous pectoralis muscle in reconstructive breast surgery: the oblique pectoralis anterior.

Huber KM, Boyd TG, Quillo AR, Wilhelmi BJ.

Eplasty. 2012;12:e44. Epub 2012 Sep 10.

48.

Degloving injuries of the oral cavity change the operative approach to fractures of the anterior segment of the mandible.

Pollock RA, Huber KM, Sickels JE.

Craniomaxillofac Trauma Reconstr. 2011 Sep;4(3):137-44. doi: 10.1055/s-0031-1286116.

49.
50.

Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.

Ronesi JA, Collins KA, Hays SA, Tsai NP, Guo W, Birnbaum SG, Hu JH, Worley PF, Gibson JR, Huber KM.

Nat Neurosci. 2012 Jan 22;15(3):431-40, S1. doi: 10.1038/nn.3033.

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