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Engineered heart tissue models from hiPSC-derived cardiomyocytes and cardiac ECM for disease modeling and drug testing applications.

Goldfracht I, Efraim Y, Shinnawi R, Kovalev E, Huber I, Gepstein A, Arbel G, Shaheen N, Tiburcy M, Zimmermann WH, Machluf M, Gepstein L.

Acta Biomater. 2019 Jul 1;92:145-159. doi: 10.1016/j.actbio.2019.05.016. Epub 2019 May 7.


Modeling Reentry in the Short QT Syndrome With Human-Induced Pluripotent Stem Cell-Derived Cardiac Cell Sheets.

Shinnawi R, Shaheen N, Huber I, Shiti A, Arbel G, Gepstein A, Ballan N, Setter N, Tijsen AJ, Borggrefe M, Gepstein L.

J Am Coll Cardiol. 2019 May 14;73(18):2310-2324. doi: 10.1016/j.jacc.2019.02.055.


Modeling Peripartum Cardiomyopathy With Human Induced Pluripotent Stem Cells Reveals Distinctive Abnormal Function of Cardiomyocytes.

Naftali-Shani N, Molotski N, Nevo-Caspi Y, Arad M, Kuperstein R, Amit U, Huber I, Zeltzer LA, Levich A, Abbas H, Monserrat L, Paret G, Leor J.

Circulation. 2018 Dec 4;138(23):2721-2723. doi: 10.1161/CIRCULATIONAHA.118.035950. No abstract available.


Internal sample process control improves cultivation-independent quantification of thermotolerant Campylobacter.

Pacholewicz E, Buhler C, Wulsten IF, Kraushaar B, Luu HQ, Iwobi AN, Huber I, Stingl K.

Food Microbiol. 2019 Apr;78:53-61. doi: 10.1016/ Epub 2018 Oct 1.


Further delineation of Malan syndrome.

Priolo M, Schanze D, Tatton-Brown K, Mulder PA, Tenorio J, Kooblall K, Acero IH, Alkuraya FS, Arias P, Bernardini L, Bijlsma EK, Cole T, Coubes C, Dapia I, Davies S, Di Donato N, Elcioglu NH, Fahrner JA, Foster A, González NG, Huber I, Iascone M, Kaiser AS, Kamath A, Liebelt J, Lynch SA, Maas SM, Mammì C, Mathijssen IB, McKee S, Menke LA, Mirzaa GM, Montgomery T, Neubauer D, Neumann TE, Pintomalli L, Pisanti MA, Plomp AS, Price S, Salter C, Santos-Simarro F, Sarda P, Segovia M, Shaw-Smith C, Smithson S, Suri M, Valdez RM, Van Haeringen A, Van Hagen JM, Zollino M, Lapunzina P, Thakker RV, Zenker M, Hennekam RC.

Hum Mutat. 2018 Sep;39(9):1226-1237. doi: 10.1002/humu.23563. Epub 2018 Jun 25.


Human Induced Pluripotent Stem Cell-Derived Cardiac Cell Sheets Expressing Genetically Encoded Voltage Indicator for Pharmacological and Arrhythmia Studies.

Shaheen N, Shiti A, Huber I, Shinnawi R, Arbel G, Gepstein A, Setter N, Goldfracht I, Gruber A, Chorna SV, Gepstein L.

Stem Cell Reports. 2018 Jun 5;10(6):1879-1894. doi: 10.1016/j.stemcr.2018.04.006. Epub 2018 May 10.


1st German Phage Symposium-Conference Report.

Huber I, Potapova K, Kuhn A, Schmidt H, Hinrichs J, Rohde C, Beyer W.

Viruses. 2018 Mar 29;10(4). pii: E158. doi: 10.3390/v10040158.


Direct Molecular Detection and Genotyping of Borrelia burgdorferi Sensu Lato in Cerebrospinal Fluid of Children with Lyme Neuroborreliosis.

Barstad B, Quarsten H, Tveitnes D, Noraas S, Ask IS, Saeed M, Bosse F, Vigemyr G, Huber I, Øymar K.

J Clin Microbiol. 2018 Apr 25;56(5). pii: e01868-17. doi: 10.1128/JCM.01868-17. Print 2018 May.


Inter-laboratory analysis of selected genetically modified plant reference materials with digital PCR.

Dobnik D, Demšar T, Huber I, Gerdes L, Broeders S, Roosens N, Debode F, Berben G, Žel J.

Anal Bioanal Chem. 2018 Jan;410(1):211-221. doi: 10.1007/s00216-017-0711-1. Epub 2017 Oct 25.


Epidemiological study of failures of the Jaipur Foot.

Huber I, Fischenich KM, Wolynski J, Niese B, Teater R, Mali HS, Jain AK, Sorby S, Abrams L, Haut Donahue TL.

Disabil Rehabil Assist Technol. 2018 Nov;13(8):740-744. doi: 10.1080/17483107.2017.1369593. Epub 2017 Aug 26.


Construction of Recombinant Pdu Metabolosome Shells for Small Molecule Production in Corynebacterium glutamicum.

Huber I, Palmer DJ, Ludwig KN, Brown IR, Warren MJ, Frunzke J.

ACS Synth Biol. 2017 Nov 17;6(11):2145-2156. doi: 10.1021/acssynbio.7b00167. Epub 2017 Sep 1.


Cerebrospinal Fluid B-lymphocyte Chemoattractant CXCL13 in the Diagnosis of Acute Lyme Neuroborreliosis in Children.

Barstad B, Tveitnes D, Noraas S, Selvik Ask I, Saeed M, Bosse F, Vigemyr G, Huber I, Øymar K.

Pediatr Infect Dis J. 2017 Dec;36(12):e286-e292. doi: 10.1097/INF.0000000000001669.


Patient-Specific Drug Screening Using a Human Induced Pluripotent Stem Cell Model of Catecholaminergic Polymorphic Ventricular Tachycardia Type 2.

Maizels L, Huber I, Arbel G, Tijsen AJ, Gepstein A, Khoury A, Gepstein L.

Circ Arrhythm Electrophysiol. 2017 Jun;10(6). pii: e004725. doi: 10.1161/CIRCEP.116.004725.


Heterologous expression of the Halothiobacillus neapolitanus carboxysomal gene cluster in Corynebacterium glutamicum.

Baumgart M, Huber I, Abdollahzadeh I, Gensch T, Frunzke J.

J Biotechnol. 2017 Sep 20;258:126-135. doi: 10.1016/j.jbiotec.2017.03.019. Epub 2017 Mar 27.


Clinical and serological one-year follow-up of patients after the bite of Ixodes ricinus ticks infected with Borrelia burgdorferi sensu lato.

Briciu VT, Flonta M, Ţăţulescu DF, Meyer F, Sebah D, Cârstina D, Mihalca AD, Gherman CM, Hizo-Teufel C, Huber I, Fingerle V, Lupșe M.

Infect Dis (Lond). 2017 Apr;49(4):277-285. doi: 10.1080/23744235.2016.1258488. Epub 2016 Nov 21.


Folding of Fibroblast Growth Factor 1 Is Critical for Its Nonclassical Release.

Prudovsky I, Kacer D, Davis J, Shah V, Jayanthi S, Huber I, Dakshinamurthy R, Ganter O, Soldi R, Neivandt D, Guvench O, Suresh Kumar TK.

Biochemistry. 2016 Feb 23;55(7):1159-67. doi: 10.1021/acs.biochem.5b01341. Epub 2016 Feb 11.


Immunohistochemistry and real-time PCR as diagnostic tools for detection of Borrelia burgdorferi sensu lato in ticks collected from humans.

Briciu VT, Sebah D, Coroiu G, Lupşe M, Cârstina D, Ţăţulescu DF, Mihalca AD, Gherman CM, Leucuţa D, Meyer F, Hizo-Teufel C, Fingerle V, Huber I.

Exp Appl Acarol. 2016 May;69(1):49-60. doi: 10.1007/s10493-016-0012-y. Epub 2016 Jan 22.


Enterococcus faecalis from Food, Clinical Specimens, and Oral Sites: Prevalence of Virulence Factors in Association with Biofilm Formation.

Anderson AC, Jonas D, Huber I, Karygianni L, Wölber J, Hellwig E, Arweiler N, Vach K, Wittmer A, Al-Ahmad A.

Front Microbiol. 2016 Jan 11;6:1534. doi: 10.3389/fmicb.2015.01534. eCollection 2015.


Monitoring Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes with Genetically Encoded Calcium and Voltage Fluorescent Reporters.

Shinnawi R, Huber I, Maizels L, Shaheen N, Gepstein A, Arbel G, Tijsen AJ, Gepstein L.

Stem Cell Reports. 2015 Oct 13;5(4):582-96. doi: 10.1016/j.stemcr.2015.08.009. Epub 2015 Sep 12.


Investigating the dynamics of recombinant protein secretion from a microalgal host.

Lauersen KJ, Huber I, Wichmann J, Baier T, Leiter A, Gaukel V, Kartushin V, Rattenholl A, Steinweg C, von Riesen L, Posten C, Gudermann F, Lütkemeyer D, Mussgnug JH, Kruse O.

J Biotechnol. 2015 Dec 10;215:62-71. doi: 10.1016/j.jbiotec.2015.05.001. Epub 2015 May 11.


Identification of bacteria isolated from veterinary clinical specimens using MALDI-TOF MS.

Pavlovic M, Wudy C, Zeller-Peronnet V, Maggipinto M, Zimmermann P, Straubinger A, Iwobi A, Märtlbauer E, Busch U, Huber I.

Berl Munch Tierarztl Wochenschr. 2015 Jan-Feb;128(1-2):24-30.


A multiplex real-time PCR method for the quantification of beef and pork fractions in minced meat.

Iwobi A, Sebah D, Kraemer I, Losher C, Fischer G, Busch U, Huber I.

Food Chem. 2015 Feb 15;169:305-13. doi: 10.1016/j.foodchem.2014.07.139. Epub 2014 Aug 8.


MALDI-TOF MS based identification of food-borne yeast isolates.

Pavlovic M, Mewes A, Maggipinto M, Schmidt W, Messelhäußer U, Balsliemke J, Hörmansdorfer S, Busch U, Huber I.

J Microbiol Methods. 2014 Nov;106:123-128. doi: 10.1016/j.mimet.2014.08.021. Epub 2014 Sep 2.


Corynebacterium species nasal carriage in pigs and their farmers in Bavaria, Germany: implications for public health.

Boschert V, Berger A, Konrad R, Huber I, Hörmansdorfer S, Zöls S, Eddicks M, Ritzmann M, Sing A.

Vet Rec. 2014 Sep 13;175(10):248. doi: 10.1136/vr.102634. Epub 2014 Jul 18.


Novel physico-chemical diagnostic tools for high throughput identification of bovine mastitis associated gram-positive, catalase-negative cocci.

Schabauer L, Wenning M, Huber I, Ehling-Schulz M.

BMC Vet Res. 2014 Jul 11;10:156. doi: 10.1186/1746-6148-10-156.


Real-time PCR-based identification of Borrelia burgdorferi sensu lato species in ticks collected from humans in Romania.

Briciu VT, Meyer F, Sebah D, Tăţulescu DF, Coroiu G, Lupşe M, Carstina D, Mihalca AD, Hizo-Teufel C, Klier C, Huber I, Fingerle V.

Ticks Tick Borne Dis. 2014 Sep;5(5):575-81. doi: 10.1016/j.ttbdis.2014.04.007. Epub 2014 Jun 29.


Identification and differentiation of food-related bacteria: A comparison of FTIR spectroscopy and MALDI-TOF mass spectrometry.

Wenning M, Breitenwieser F, Konrad R, Huber I, Busch U, Scherer S.

J Microbiol Methods. 2014 Aug;103:44-52. doi: 10.1016/j.mimet.2014.05.011. Epub 2014 May 28.


Comparative assessment of DNA-based approaches for the quantification of food allergens.

Luber F, Demmel A, Herbert D, Hosken A, Hupfer C, Huber I, Busch U, Engel KH.

Food Chem. 2014 Oct 1;160:104-11. doi: 10.1016/j.foodchem.2014.03.077. Epub 2014 Mar 24.


[The importance of wildlife as reservoir of antibiotic-resistant bacteria in Bavaria--first results].

Meyer C, Heurich M, Huber I, Krause G, Ullrich U, Fetsch A.

Berl Munch Tierarztl Wochenschr. 2014 Mar-Apr;127(3-4):129-34. German.


"Limits of control"--crucial parameters for a reliable quantification of viable campylobacter by real-time PCR.

Krüger NJ, Buhler C, Iwobi AN, Huber I, Ellerbroek L, Appel B, Stingl K.

PLoS One. 2014 Feb 5;9(2):e88108. doi: 10.1371/journal.pone.0088108. eCollection 2014.


Application of MALDI-TOF MS for the Identification of Food Borne Bacteria.

Pavlovic M, Huber I, Konrad R, Busch U.

Open Microbiol J. 2013 Nov 15;7:135-41. doi: 10.2174/1874285801307010135. eCollection 2013.


Modeling of arrhythmogenic right ventricular cardiomyopathy with human induced pluripotent stem cells.

Caspi O, Huber I, Gepstein A, Arbel G, Maizels L, Boulos M, Gepstein L.

Circ Cardiovasc Genet. 2013 Dec;6(6):557-68. doi: 10.1161/CIRCGENETICS.113.000188. Epub 2013 Nov 7.


Development and validation of duplex, triplex, and pentaplex real-time PCR screening assays for the detection of genetically modified organisms in food and feed.

Huber I, Block A, Sebah D, Debode F, Morisset D, Grohmann L, Berben G, Stebih D, Milavec M, Zel J, Busch U.

J Agric Food Chem. 2013 Oct 30;61(43):10293-301. doi: 10.1021/jf402448y. Epub 2013 Oct 18.


The GMOseek matrix: a decision support tool for optimizing the detection of genetically modified plants.

Block A, Debode F, Grohmann L, Hulin J, Taverniers I, Kluga L, Barbau-Piednoir E, Broeders S, Huber I, Van den Bulcke M, Heinze P, Berben G, Busch U, Roosens N, Janssen E, Žel J, Gruden K, Morisset D.

BMC Bioinformatics. 2013 Aug 22;14:256. doi: 10.1186/1471-2105-14-256.


[The figure play therapy: a psychotherapy oriented form of play and art therapy for children and adolescents].

Huber I, Künzle C.

Kinderkrankenschwester. 2013 Feb;32(2):68-9. German. No abstract available.


Grazing resistant freshwater bacteria profit from chitin and cell-wall-derived organic carbon.

Eckert EM, Baumgartner M, Huber IM, Pernthaler J.

Environ Microbiol. 2013 Jul;15(7):2019-30. doi: 10.1111/1462-2920.12083. Epub 2013 Feb 17.


Leptospira spp. strain identification by MALDI TOF MS is an equivalent tool to 16S rRNA gene sequencing and multi locus sequence typing (MLST).

Rettinger A, Krupka I, Grünwald K, Dyachenko V, Fingerle V, Konrad R, Raschel H, Busch U, Sing A, Straubinger RK, Huber I.

BMC Microbiol. 2012 Aug 27;12:185.


Modeling of catecholaminergic polymorphic ventricular tachycardia with patient-specific human-induced pluripotent stem cells.

Itzhaki I, Maizels L, Huber I, Gepstein A, Arbel G, Caspi O, Miller L, Belhassen B, Nof E, Glikson M, Gepstein L.

J Am Coll Cardiol. 2012 Sep 11;60(11):990-1000. doi: 10.1016/j.jacc.2012.02.066. Epub 2012 Jun 27.


Sexually transmitted diphtheria.

Berger A, Lensing C, Konrad R, Huber I, Hogardt M, Sing A.

Sex Transm Infect. 2013 Mar;89(2):100-1. doi: 10.1136/sextrans-2011-050418. Epub 2012 May 23.


Derivation and cardiomyocyte differentiation of induced pluripotent stem cells from heart failure patients.

Zwi-Dantsis L, Huber I, Habib M, Winterstern A, Gepstein A, Arbel G, Gepstein L.

Eur Heart J. 2013 Jun;34(21):1575-86. doi: 10.1093/eurheartj/ehs096. Epub 2012 May 22.


Universal real-time PCR for the detection and quantification of adeno-associated virus serotype 2-derived inverted terminal repeat sequences.

Aurnhammer C, Haase M, Muether N, Hausl M, Rauschhuber C, Huber I, Nitschko H, Busch U, Sing A, Ehrhardt A, Baiker A.

Hum Gene Ther Methods. 2012 Feb;23(1):18-28. doi: 10.1089/hgtb.2011.034.


A dual approach employing MALDI-TOF MS and real-time PCR for fast species identification within the Enterobacter cloacae complex.

Pavlovic M, Konrad R, Iwobi AN, Sing A, Busch U, Huber I.

FEMS Microbiol Lett. 2012 Mar;328(1):46-53. doi: 10.1111/j.1574-6968.2011.02479.x. Epub 2012 Jan 11.


Human diphtheria infection from a cat bite.

Berger A, Schmidt-Wieland T, Huber I, Sing A.

Ann Intern Med. 2011 Nov 1;155(9):646-8. doi: 10.7326/0003-4819-155-9-201111010-00021. No abstract available.


Toxigenic Corynebacterium ulcerans in woman and cat.

Berger A, Huber I, Merbecks SS, Ehrhard I, Konrad R, Hörmansdorfer S, Hogardt M, Sing A.

Emerg Infect Dis. 2011 Sep;17(9):1767-9. doi: 10.3201/eid1709.110391. No abstract available.


Calcium handling in human induced pluripotent stem cell derived cardiomyocytes.

Itzhaki I, Rapoport S, Huber I, Mizrahi I, Zwi-Dantsis L, Arbel G, Schiller J, Gepstein L.

PLoS One. 2011 Apr 1;6(4):e18037. doi: 10.1371/journal.pone.0018037.


A multiplex one-step real-time RT-PCR assay for influenza surveillance.

Huber I, Campe H, Sebah D, Hartberger C, Konrad R, Bayer M, Busch U, Sing A.

Euro Surveill. 2011 Feb 17;16(7). pii: 19798.


Development of a duplex real-time PCR for differentiation between E. coli and Shigella spp.

Pavlovic M, Luze A, Konrad R, Berger A, Sing A, Busch U, Huber I.

J Appl Microbiol. 2011 May;110(5):1245-51. doi: 10.1111/j.1365-2672.2011.04973.x. Epub 2011 Mar 14.


Modelling the long QT syndrome with induced pluripotent stem cells.

Itzhaki I, Maizels L, Huber I, Zwi-Dantsis L, Caspi O, Winterstern A, Feldman O, Gepstein A, Arbel G, Hammerman H, Boulos M, Gepstein L.

Nature. 2011 Mar 10;471(7337):225-9. doi: 10.1038/nature09747. Epub 2011 Jan 16.


Matrix-assisted laser desorption/ionisation time-of-flight (MALDI-TOF) mass spectrometry as a tool for rapid diagnosis of potentially toxigenic Corynebacterium species in the laboratory management of diphtheria-associated bacteria.

Konrad R, Berger A, Huber I, Boschert V, Hörmansdorfer S, Busch U, Hogardt M, Schubert S, Sing A.

Euro Surveill. 2010 Oct 28;15(43). pii: 19699. Erratum in: Euro Surveill. 2010;15(44)pii:19702.


In vivo assessment of the electrophysiological integration and arrhythmogenic risk of myocardial cell transplantation strategies.

Gepstein L, Ding C, Rahmutula D, Wilson EE, Yankelson L, Caspi O, Gepstein A, Huber I, Olgin JE.

Stem Cells. 2010 Dec;28(12):2151-61. doi: 10.1002/stem.545. Erratum in: Stem Cells. 2011 Sep;29(9):1475. Rehemedula, Dolkun [corrected to Rahmutula, Dolkun].

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