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Items: 17

1.

Regulation of cell proliferation by hypoxia-inducible factors.

Hubbi ME, Semenza GL.

Am J Physiol Cell Physiol. 2015 Dec 15;309(12):C775-82. doi: 10.1152/ajpcell.00279.2015. Epub 2015 Oct 21. Review.

2.

Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase.

Ahmed I, Sbodio JI, Harraz MM, Tyagi R, Grima JC, Albacarys LK, Hubbi ME, Xu R, Kim S, Paul BD, Snyder SH.

Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):9751-6. doi: 10.1073/pnas.1511810112. Epub 2015 Jul 20.

3.

An essential role for chaperone-mediated autophagy in cell cycle progression.

Hubbi ME, Semenza GL.

Autophagy. 2015;11(5):850-1. doi: 10.1080/15548627.2015.1037063.

4.

Control of the interface between heterotypic cell populations reveals the mechanism of intercellular transfer of signaling proteins.

Kshitiz, Afzal J, Suhail Y, Ahn EH, Goyal R, Hubbi ME, Hussaini Q, Ellison DD, Goyal J, Nacev B, Kim DH, Lee JH, Frankel S, Gray K, Bankoti R, Chien AJ, Levchenko A.

Integr Biol (Camb). 2015 Mar;7(3):364-72.

PMID:
25784457
5.

Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression.

Hubbi ME, Gilkes DM, Hu H, Kshitiz, Ahmed I, Semenza GL.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3325-34. doi: 10.1073/pnas.1412840111. Epub 2014 Jul 28.

6.

Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells.

Gilkes DM, Xiang L, Lee SJ, Chaturvedi P, Hubbi ME, Wirtz D, Semenza GL.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):E384-93. doi: 10.1073/pnas.1321510111. Epub 2013 Dec 9.

7.

Sirtuin-7 inhibits the activity of hypoxia-inducible factors.

Hubbi ME, Hu H, Kshitiz, Gilkes DM, Semenza GL.

J Biol Chem. 2013 Jul 19;288(29):20768-75. doi: 10.1074/jbc.M113.476903. Epub 2013 Jun 9.

8.

Collagen prolyl hydroxylases are essential for breast cancer metastasis.

Gilkes DM, Chaturvedi P, Bajpai S, Wong CC, Wei H, Pitcairn S, Hubbi ME, Wirtz D, Semenza GL.

Cancer Res. 2013 Jun 1;73(11):3285-96. doi: 10.1158/0008-5472.CAN-12-3963. Epub 2013 Mar 28.

9.

Chaperone-mediated autophagy targets hypoxia-inducible factor-1α (HIF-1α) for lysosomal degradation.

Hubbi ME, Hu H, Kshitiz, Ahmed I, Levchenko A, Semenza GL.

J Biol Chem. 2013 Apr 12;288(15):10703-14. doi: 10.1074/jbc.M112.414771. Epub 2013 Mar 1.

10.

A nontranscriptional role for HIF-1α as a direct inhibitor of DNA replication.

Hubbi ME, Kshitiz, Gilkes DM, Rey S, Wong CC, Luo W, Kim DH, Dang CV, Levchenko A, Semenza GL.

Sci Signal. 2013 Feb 12;6(262):ra10. doi: 10.1126/scisignal.2003417.

11.

Procollagen lysyl hydroxylase 2 is essential for hypoxia-induced breast cancer metastasis.

Gilkes DM, Bajpai S, Wong CC, Chaturvedi P, Hubbi ME, Wirtz D, Semenza GL.

Mol Cancer Res. 2013 May;11(5):456-66. doi: 10.1158/1541-7786.MCR-12-0629. Epub 2013 Feb 1.

12.

Matrix rigidity controls endothelial differentiation and morphogenesis of cardiac precursors.

Kshitiz, Hubbi ME, Ahn EH, Downey J, Afzal J, Kim DH, Rey S, Chang C, Kundu A, Semenza GL, Abraham RM, Levchenko A.

Sci Signal. 2012 Jun 5;5(227):ra41. doi: 10.1126/scisignal.2003002. Erratum in: Sci Signal. 2012 Oct 9;5(245):er6.

13.

Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis.

Wong CC, Zhang H, Gilkes DM, Chen J, Wei H, Chaturvedi P, Hubbi ME, Semenza GL.

J Mol Med (Berl). 2012 Jul;90(7):803-15. doi: 10.1007/s00109-011-0855-y. Epub 2012 Jan 10.

14.

Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1.

Hubbi ME, Gilkes DM, Baek JH, Semenza GL.

J Biol Chem. 2012 Feb 24;287(9):6139-49. doi: 10.1074/jbc.M111.278630. Epub 2012 Jan 4.

15.

MCM proteins are negative regulators of hypoxia-inducible factor 1.

Hubbi ME, Luo W, Baek JH, Semenza GL.

Mol Cell. 2011 Jun 10;42(5):700-12. doi: 10.1016/j.molcel.2011.03.029.

16.

Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization.

Liu YV, Hubbi ME, Pan F, McDonald KR, Mansharamani M, Cole RN, Liu JO, Semenza GL.

J Biol Chem. 2007 Dec 21;282(51):37064-73. Epub 2007 Oct 26.

17.

Spermidine/spermine-N1-acetyltransferase 2 is an essential component of the ubiquitin ligase complex that regulates hypoxia-inducible factor 1alpha.

Baek JH, Liu YV, McDonald KR, Wesley JB, Hubbi ME, Byun H, Semenza GL.

J Biol Chem. 2007 Aug 10;282(32):23572-80. Epub 2007 Jun 8.

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