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Items: 1 to 50 of 385

1.

Improving Efficacy and Safety of Agonistic Anti-CD40 Antibody Through Extracellular Matrix Affinity.

Ishihara J, Ishihara A, Potin L, Hosseinchi P, Fukunaga K, Damo M, Gajewski TF, Swartz MA, Hubbell JA.

Mol Cancer Ther. 2018 Aug 10. doi: 10.1158/1535-7163.MCT-18-0091. [Epub ahead of print]

PMID:
30097487
2.

Fiber density of collagen grafts impacts rabbit urethral regeneration.

Larsson HM, Vythilingam G, Pinnagoda K, Vardar E, Engelhardt EM, Sothilingam S, Thambidorai RC, Kamarul T, Hubbell JA, Frey P.

Sci Rep. 2018 Jul 3;8(1):10057. doi: 10.1038/s41598-018-27621-9.

3.

Total intravenous anesthesia using a midazolam-ketamine-xylazine infusion in horses: 46 cases (2011-2014).

Aarnes TK, Lerche P, Bednarski RM, Hubbell JAE.

Can Vet J. 2018 May;59(5):500-504.

PMID:
29904202
4.

Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing.

Ishihara J, Ishihara A, Fukunaga K, Sasaki K, White MJV, Briquez PS, Hubbell JA.

Nat Commun. 2018 Jun 4;9(1):2163. doi: 10.1038/s41467-018-04525-w.

5.

Modified Magnesium Hydroxide Nanoparticles Inhibit the Inflammatory Response to Biodegradable Poly(lactide- co-glycolide) Implants.

Lih E, Kum CH, Park W, Chun SY, Cho Y, Joung YK, Park KS, Hong YJ, Ahn DJ, Kim BS, Kwon TG, Jeong MH, Hubbell JA, Han DK.

ACS Nano. 2018 Jul 24;12(7):6917-6925. doi: 10.1021/acsnano.8b02365. Epub 2018 Jun 8.

PMID:
29812907
6.

Adaptive enhanced sampling by force-biasing using neural networks.

Guo AZ, Sevgen E, Sidky H, Whitmer JK, Hubbell JA, de Pablo JJ.

J Chem Phys. 2018 Apr 7;148(13):134108. doi: 10.1063/1.5020733.

PMID:
29626875
7.

Microfluidic production of bioactive fibrin micro-beads embedded in crosslinked collagen used as an injectable bulking agent for urinary incontinence treatment.

Vardar E, Larsson HM, Allazetta S, Engelhardt EM, Pinnagoda K, Vythilingam G, Hubbell JA, Lutolf MP, Frey P.

Acta Biomater. 2018 Feb;67:156-166. doi: 10.1016/j.actbio.2017.11.034. Epub 2017 Nov 29.

PMID:
29197579
8.

Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events.

Ishihara J, Fukunaga K, Ishihara A, Larsson HM, Potin L, Hosseinchi P, Galliverti G, Swartz MA, Hubbell JA.

Sci Transl Med. 2017 Nov 8;9(415). pii: eaan0401. doi: 10.1126/scitranslmed.aan0401.

PMID:
29118259
9.

Immunoisolation of murine islet allografts in vascularized sites through conformal coating with polyethylene glycol.

Manzoli V, Villa C, Bayer AL, Morales LC, Molano RD, Torrente Y, Ricordi C, Hubbell JA, Tomei AA.

Am J Transplant. 2018 Mar;18(3):590-603. doi: 10.1111/ajt.14547. Epub 2017 Dec 2.

PMID:
29068143
10.

Oxidation-sensitive polymersomes as vaccine nanocarriers enhance humoral responses against Lassa virus envelope glycoprotein.

Galan-Navarro C, Rincon-Restrepo M, Zimmer G, Ollmann Saphire E, Hubbell JA, Hirosue S, Swartz MA, Kunz S.

Virology. 2017 Dec;512:161-171. doi: 10.1016/j.virol.2017.09.013. Epub 2017 Sep 28.

PMID:
28963882
11.

Bioengineering strategies for inducing tolerance in autoimmune diabetes.

Baekkeskov S, Hubbell JA, Phelps EA.

Adv Drug Deliv Rev. 2017 May 15;114:256-265. doi: 10.1016/j.addr.2017.06.007. Epub 2017 Jun 15. Review.

PMID:
28625830
12.

Corrigendum: Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation.

Phelps EA, Cianciaruso C, Santo-Domingo J, Pasquier M, Galliverti G, Piemonti L, Berishvili E, Burri O, Wiederkehr A, Hubbell JA, Baekkeskov S.

Sci Rep. 2017 May 9;7:46801. doi: 10.1038/srep46801. No abstract available.

13.

Human Kunitz-type protease inhibitor engineered for enhanced matrix retention extends longevity of fibrin biomaterials.

Briquez PS, Lorentz KM, Larsson HM, Frey P, Hubbell JA.

Biomaterials. 2017 Aug;135:1-9. doi: 10.1016/j.biomaterials.2017.04.048. Epub 2017 Apr 29.

14.

Local induction of lymphangiogenesis with engineered fibrin-binding VEGF-C promotes wound healing by increasing immune cell trafficking and matrix remodeling.

Güç E, Briquez PS, Foretay D, Fankhauser MA, Hubbell JA, Kilarski WW, Swartz MA.

Biomaterials. 2017 Jul;131:160-175. doi: 10.1016/j.biomaterials.2017.03.033. Epub 2017 Mar 25.

15.

Vaccine nanocarriers: Coupling intracellular pathways and cellular biodistribution to control CD4 vs CD8 T cell responses.

Rincon-Restrepo M, Mayer A, Hauert S, Bonner DK, Phelps EA, Hubbell JA, Swartz MA, Hirosue S.

Biomaterials. 2017 Jul;132:48-58. doi: 10.1016/j.biomaterials.2017.03.047. Epub 2017 Mar 30.

PMID:
28407494
16.

Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation.

Phelps EA, Cianciaruso C, Santo-Domingo J, Pasquier M, Galliverti G, Piemonti L, Berishvili E, Burri O, Wiederkehr A, Hubbell JA, Baekkeskov S.

Sci Rep. 2017 Apr 12;7:45961. doi: 10.1038/srep45961. Erratum in: Sci Rep. 2017 May 09;7:46801.

17.

Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses.

Dowling DJ, Scott EA, Scheid A, Bergelson I, Joshi S, Pietrasanta C, Brightman S, Sanchez-Schmitz G, Van Haren SD, Ninković J, Kats D, Guiducci C, de Titta A, Bonner DK, Hirosue S, Swartz MA, Hubbell JA, Levy O.

J Allergy Clin Immunol. 2017 Nov;140(5):1339-1350. doi: 10.1016/j.jaci.2016.12.985. Epub 2017 Mar 23.

18.

Pharmacokinetics of intravenous and transdermal fentanyl in alpacas.

Lovasz M, Aarnes TK, Hubbell JAE, Bednarski RM, Lerche P, Lakritz J.

J Vet Pharmacol Ther. 2017 Dec;40(6):663-669. doi: 10.1111/jvp.12403. Epub 2017 Mar 19.

PMID:
28317124
19.

Pharmacokinetics and pharmacodynamics of buprenorphine and sustained-release buprenorphine after administration to adult alpacas.

Dooley SB, Aarnes TK, Lakritz J, Lerche P, Bednarski RM, Hubbell JA.

Am J Vet Res. 2017 Mar;78(3):321-329. doi: 10.2460/ajvr.78.3.321.

PMID:
28240955
20.
21.

(Re)Building a Kidney.

Oxburgh L, Carroll TJ, Cleaver O, Gossett DR, Hoshizaki DK, Hubbell JA, Humphreys BD, Jain S, Jensen J, Kaplan DL, Kesselman C, Ketchum CJ, Little MH, McMahon AP, Shankland SJ, Spence JR, Valerius MT, Wertheim JA, Wessely O, Zheng Y, Drummond IA.

J Am Soc Nephrol. 2017 May;28(5):1370-1378. doi: 10.1681/ASN.2016101077. Epub 2017 Jan 17.

22.

Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.

Cianciaruso C, Phelps EA, Pasquier M, Hamelin R, Demurtas D, Alibashe Ahmed M, Piemonti L, Hirosue S, Swartz MA, De Palma M, Hubbell JA, Baekkeskov S.

Diabetes. 2017 Feb;66(2):460-473. doi: 10.2337/db16-0671. Epub 2016 Nov 21.

23.

Difference in suitable mechanical properties of three-dimensional, synthetic scaffolds for self-renewing mouse embryonic stem cells of different genetic backgrounds.

Lee M, Ahn JI, Ahn JY, Yang WS, Hubbell JA, Lim JM, Lee ST.

J Biomed Mater Res B Appl Biomater. 2017 Nov;105(8):2261-2268. doi: 10.1002/jbm.b.33763. Epub 2016 Jul 26.

PMID:
27459401
24.

Engineered acellular collagen scaffold for endogenous cell guidance, a novel approach in urethral regeneration.

Pinnagoda K, Larsson HM, Vythilingam G, Vardar E, Engelhardt EM, Thambidorai RC, Hubbell JA, Frey P.

Acta Biomater. 2016 Oct 1;43:208-217. doi: 10.1016/j.actbio.2016.07.033. Epub 2016 Jul 19.

PMID:
27450527
25.

IGF-1-containing multi-layered collagen-fibrin hybrid scaffolds for bladder tissue engineering.

Vardar E, Larsson HM, Engelhardt EM, Pinnagoda K, Briquez PS, Hubbell JA, Frey P.

Acta Biomater. 2016 Sep 1;41:75-85. doi: 10.1016/j.actbio.2016.06.010. Epub 2016 Jun 7.

PMID:
27286676
26.

Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity.

Phelps EA, Cianciaruso C, Michael IP, Pasquier M, Kanaani J, Nano R, Lavallard V, Billestrup N, Hubbell JA, Baekkeskov S.

Diabetes. 2016 Sep;65(9):2686-99. doi: 10.2337/db16-0180. Epub 2016 Jun 9.

27.

Fibronectin EDA and CpG synergize to enhance antigen-specific Th1 and cytotoxic responses.

Julier Z, de Titta A, Grimm AJ, Simeoni E, Swartz MA, Hubbell JA.

Vaccine. 2016 May 5;34(21):2453-2459. doi: 10.1016/j.vaccine.2016.03.057. Epub 2016 Mar 24.

28.

Hollow Mesoporous Plasmonic Nanoshells for Enhanced Solar Vapor Generation.

Zielinski MS, Choi JW, La Grange T, Modestino M, Hashemi SM, Pu Y, Birkhold S, Hubbell JA, Psaltis D.

Nano Lett. 2016 Apr 13;16(4):2159-67. doi: 10.1021/acs.nanolett.5b03901. Epub 2016 Mar 3.

PMID:
26918518
29.

TLR-3 stimulation improves anti-tumor immunity elicited by dendritic cell exosome-based vaccines in a murine model of melanoma.

Damo M, Wilson DS, Simeoni E, Hubbell JA.

Sci Rep. 2015 Dec 3;5:17622. doi: 10.1038/srep17622.

30.

Engineered binding to erythrocytes induces immunological tolerance to E. coli asparaginase.

Lorentz KM, Kontos S, Diaceri G, Henry H, Hubbell JA.

Sci Adv. 2015 Jul 17;1(6):e1500112. doi: 10.1126/sciadv.1500112. eCollection 2015 Jul.

31.

Engineering growth factors for regenerative medicine applications.

Mitchell AC, Briquez PS, Hubbell JA, Cochran JR.

Acta Biomater. 2016 Jan;30:1-12. doi: 10.1016/j.actbio.2015.11.007. Epub 2015 Nov 7. Review.

32.

Memory of tolerance and induction of regulatory T cells by erythrocyte-targeted antigens.

Grimm AJ, Kontos S, Diaceri G, Quaglia-Thermes X, Hubbell JA.

Sci Rep. 2015 Oct 29;5:15907. doi: 10.1038/srep15907.

33.

Kinetics of Ultrasonic Drug Delivery from Targeted Micelles.

Husseinil GA, Kherbeckl L, Pitt WG, Hubbell JA, Christensen DA, Velluto D.

J Nanosci Nanotechnol. 2015 Mar;15(3):2099-104.

PMID:
26413626
34.

Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice.

Ballester M, Jeanbart L, de Titta A, Nembrini C, Marsland BJ, Hubbell JA, Swartz MA.

Sci Rep. 2015 Sep 21;5:14274. doi: 10.1038/srep14274.

35.

Extracellular Matrix-Inspired Growth Factor Delivery Systems for Skin Wound Healing.

Briquez PS, Hubbell JA, Martino MM.

Adv Wound Care (New Rochelle). 2015 Aug 1;4(8):479-489. Review.

36.

Engineering antigen-specific immunological tolerance.

Kontos S, Grimm AJ, Hubbell JA.

Curr Opin Immunol. 2015 Aug;35:80-8. doi: 10.1016/j.coi.2015.05.005. Epub 2015 Jul 8. Review.

PMID:
26163377
37.

Crystalline Oligo(ethylene sulfide) Domains Define Highly Stable Supramolecular Block Copolymer Assemblies.

Brubaker CE, Velluto D, Demurtas D, Phelps EA, Hubbell JA.

ACS Nano. 2015 Jul 28;9(7):6872-81. doi: 10.1021/acsnano.5b02937. Epub 2015 Jul 8.

PMID:
26125494
38.

Tubular Compressed Collagen Scaffolds for Ureteral Tissue Engineering in a Flow Bioreactor System.

Vardar E, Engelhardt EM, Larsson HM, Mouloungui E, Pinnagoda K, Hubbell JA, Frey P.

Tissue Eng Part A. 2015 Sep;21(17-18):2334-45. doi: 10.1089/ten.TEA.2015.0048. Epub 2015 Jul 20.

PMID:
26065873
39.

Prescription for a pharmacyte.

Hubbell JA.

Sci Transl Med. 2015 Jun 10;7(291):291fs23. doi: 10.1126/scitranslmed.aac5665.

PMID:
26062842
40.

6-Thioguanine-loaded polymeric micelles deplete myeloid-derived suppressor cells and enhance the efficacy of T cell immunotherapy in tumor-bearing mice.

Jeanbart L, Kourtis IC, van der Vlies AJ, Swartz MA, Hubbell JA.

Cancer Immunol Immunother. 2015 Aug;64(8):1033-46. doi: 10.1007/s00262-015-1702-8. Epub 2015 May 16.

41.

Extracellular matrix-inspired growth factor delivery systems for bone regeneration.

Martino MM, Briquez PS, Maruyama K, Hubbell JA.

Adv Drug Deliv Rev. 2015 Nov 1;94:41-52. doi: 10.1016/j.addr.2015.04.007. Epub 2015 Apr 17. Review.

PMID:
25895621
42.

Extracellular matrix and growth factor engineering for controlled angiogenesis in regenerative medicine.

Martino MM, Brkic S, Bovo E, Burger M, Schaefer DJ, Wolff T, Gürke L, Briquez PS, Larsson HM, Gianni-Barrera R, Hubbell JA, Banfi A.

Front Bioeng Biotechnol. 2015 Apr 1;3:45. doi: 10.3389/fbioe.2015.00045. eCollection 2015. Review.

44.

Fibrin gels engineered with pro-angiogenic growth factors promote engraftment of pancreatic islets in extrahepatic sites in mice.

Najjar M, Manzoli V, Abreu M, Villa C, Martino MM, Molano RD, Torrente Y, Pileggi A, Inverardi L, Ricordi C, Hubbell JA, Tomei AA.

Biotechnol Bioeng. 2015 Sep;112(9):1916-26. doi: 10.1002/bit.25589. Epub 2015 Jul 7.

PMID:
25786390
45.

The TLR4 agonist fibronectin extra domain A is cryptic, exposed by elastase-2; use in a fibrin matrix cancer vaccine.

Julier Z, Martino MM, de Titta A, Jeanbart L, Hubbell JA.

Sci Rep. 2015 Feb 24;5:8569. doi: 10.1038/srep08569.

46.

Molecularly engineered self-assembling membranes for cell-mediated degradation.

Ferreira DS, Lin YA, Cui H, Hubbell JA, Reis RL, Azevedo HS.

Adv Healthc Mater. 2015 Mar 11;4(4):602-12. doi: 10.1002/adhm.201400586. Epub 2014 Nov 21.

PMID:
25413155
47.

Overcoming immunological barriers in regenerative medicine.

Zakrzewski JL, van den Brink MR, Hubbell JA.

Nat Biotechnol. 2014 Aug;32(8):786-94. doi: 10.1038/nbt.2960.

48.

Device design and materials optimization of conformal coating for islets of Langerhans.

Tomei AA, Manzoli V, Fraker CA, Giraldo J, Velluto D, Najjar M, Pileggi A, Molano RD, Ricordi C, Stabler CL, Hubbell JA.

Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10514-9. doi: 10.1073/pnas.1402216111. Epub 2014 Jun 30.

49.

Bioluminescent and micro-computed tomography imaging of bone repair induced by fibrin-binding growth factors.

Vila OF, Martino MM, Nebuloni L, Kuhn G, Pérez-Amodio S, Müller R, Hubbell JA, Rubio N, Blanco J.

Acta Biomater. 2014 Oct;10(10):4377-89. doi: 10.1016/j.actbio.2014.05.028. Epub 2014 Jun 4.

PMID:
24905933
50.

Enhancing efficacy of anticancer vaccines by targeted delivery to tumor-draining lymph nodes.

Jeanbart L, Ballester M, de Titta A, Corthésy P, Romero P, Hubbell JA, Swartz MA.

Cancer Immunol Res. 2014 May;2(5):436-47. doi: 10.1158/2326-6066.CIR-14-0019-T. Epub 2014 Feb 11.

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