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Items: 10

1.

Using Tox21 High-Throughput Screening Assays for the Evaluation of Botanical and Dietary Supplements.

Hubbard TD, Hsieh JH, Rider CV, Sipes NS, Sedykh A, Collins BJ, Auerbach SS, Xia M, Huang R, Walker NJ, DeVito MJ.

Appl In Vitro Toxicol. 2019 Mar 1;5(1):10-25. doi: 10.1089/aivt.2018.0020. Epub 2019 Mar 9.

2.

Microbiota Metabolism Promotes Synthesis of the Human Ah Receptor Agonist 2,8-Dihydroxyquinoline.

Hubbard TD, Liu Q, Murray IA, Dong F, Miller C 3rd, Smith PB, Gowda K, Lin JM, Amin S, Patterson AD, Perdew GH.

J Proteome Res. 2019 Apr 5;18(4):1715-1724. doi: 10.1021/acs.jproteome.8b00946. Epub 2019 Mar 4.

PMID:
30777439
3.

Dietary Broccoli Impacts Microbial Community Structure and Attenuates Chemically Induced Colitis in Mice in an Ah receptor dependent manner.

Hubbard TD, Murray IA, Nichols RG, Cassel K, Podolsky M, Kuzu G, Tian Y, Smith P, Kennett MJ, Patterson AD, Perdew GH.

J Funct Foods. 2017 Oct;37:685-698. doi: 10.1016/j.jff.2017.08.038. Epub 2017 Sep 1.

4.

Assessment of Ah receptor transcriptional activity mediated by halogenated dibenzo-p-dioxins and dibenzofurans (PXDD/Fs) in human and mouse cell systems.

Organtini KL, Hubbard TD, Perdew GH, Dorman FL.

J Environ Sci Health A Tox Hazard Subst Environ Eng. 2017 Dec 6;52(14):1295-1302. doi: 10.1080/10934529.2017.1362290. Epub 2017 Sep 18.

PMID:
28922086
5.

Ligand-mediated cytoplasmic retention of the Ah receptor inhibits macrophage-mediated acute inflammatory responses.

Muku GE, Lahoti TS, Murray IA, Podolsky MA, Smith KJ, Hubbard TD, Kuzu G, Gowda K, Amin SG, Perdew GH.

Lab Invest. 2017 Dec;97(12):1471-1487. doi: 10.1038/labinvest.2017.92. Epub 2017 Sep 11.

6.

Divergent Ah Receptor Ligand Selectivity during Hominin Evolution.

Hubbard TD, Murray IA, Bisson WH, Sullivan AP, Sebastian A, Perry GH, Jablonski NG, Perdew GH.

Mol Biol Evol. 2016 Oct;33(10):2648-58. doi: 10.1093/molbev/msw143. Epub 2016 Aug 2.

7.

A novel AhR ligand, 2AI, protects the retina from environmental stress.

Gutierrez MA, Davis SS, Rosko A, Nguyen SM, Mitchell KP, Mateen S, Neves J, Garcia TY, Mooney S, Perdew GH, Hubbard TD, Lamba DA, Ramanathan A.

Sci Rep. 2016 Jul 1;6:29025. doi: 10.1038/srep29025.

8.

Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles.

Hubbard TD, Murray IA, Bisson WH, Lahoti TS, Gowda K, Amin SG, Patterson AD, Perdew GH.

Sci Rep. 2015 Aug 3;5:12689. doi: 10.1038/srep12689.

9.

Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation.

Hubbard TD, Murray IA, Perdew GH.

Drug Metab Dispos. 2015 Oct;43(10):1522-35. doi: 10.1124/dmd.115.064246. Epub 2015 Jun 3. Review.

10.

Persistent Organic Pollutants Modify Gut Microbiota-Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation.

Zhang L, Nichols RG, Correll J, Murray IA, Tanaka N, Smith PB, Hubbard TD, Sebastian A, Albert I, Hatzakis E, Gonzalez FJ, Perdew GH, Patterson AD.

Environ Health Perspect. 2015 Jul;123(7):679-88. doi: 10.1289/ehp.1409055. Epub 2015 Mar 13.

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