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Items: 49


Functional Interactions Between rsks-1/S6K, glp-1/Notch, and Regulators of Caenorhabditis elegans Fertility and Germline Stem Cell Maintenance.

Roy D, Kahler DJ, Yun C, Hubbard EJA.

G3 (Bethesda). 2018 Oct 3;8(10):3293-3309. doi: 10.1534/g3.118.200511.


The DSL ligand APX-1 is required for normal ovulation in C. elegans.

McGovern M, Castaneda PG, Pekar O, Vallier LG, Cram EJ, Hubbard EJA.

Dev Biol. 2018 Mar 15;435(2):162-169. doi: 10.1016/j.ydbio.2018.01.009. Epub 2018 Jan 31.


Linking the environment, DAF-7/TGFβ signaling and LAG-2/DSL ligand expression in the germline stem cell niche.

Pekar O, Ow MC, Hui KY, Noyes MB, Hall SE, Hubbard EJA.

Development. 2017 Aug 15;144(16):2896-2906. doi: 10.1242/dev.147660.


How computational models contribute to our understanding of the germ line.

Atwell K, Dunn SJ, Osborne JM, Kugler H, Hubbard EJ.

Mol Reprod Dev. 2016 Nov;83(11):944-957. doi: 10.1002/mrd.22735. Epub 2016 Oct 7. Review.


Cell cycle features of C. elegans germline stem/progenitor cells vary temporally and spatially.

Roy D, Michaelson D, Hochman T, Santella A, Bao Z, Goldberg JD, Hubbard EJA.

Dev Biol. 2016 Jan 1;409(1):261-271. doi: 10.1016/j.ydbio.2015.10.031. Epub 2015 Nov 11.


Mechano-logical model of C. elegans germ line suggests feedback on the cell cycle.

Atwell K, Qin Z, Gavaghan D, Kugler H, Hubbard EJ, Osborne JM.

Development. 2015 Nov 15;142(22):3902-11. doi: 10.1242/dev.126359. Epub 2015 Oct 1.


Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors.

Deng X, Michaelson D, Tchieu J, Cheng J, Rothenstein D, Feldman R, Lee SG, Fuller J, Haimovitz-Friedman A, Studer L, Powell S, Fuks Z, Hubbard EJ, Kolesnick R.

PLoS One. 2015 Jun 29;10(6):e0127862. doi: 10.1371/journal.pone.0127862. eCollection 2015. Erratum in: PLoS One. 2016;11(1):e0141673.


Irises: A practical tool for image-based analysis of cellular DNA content.

Vogel JL, Michaelson D, Santella A, Hubbard EJ, Bao Z.

Worm. 2014 May 8;3:e29041. doi: 10.4161/worm.29041. eCollection 2014.


FLP/FRT and Cre/lox recombination technology in C. elegans.

Hubbard EJ.

Methods. 2014 Aug 1;68(3):417-24. doi: 10.1016/j.ymeth.2014.05.007. Epub 2014 May 27.


Diet and genetics: Trp-ing over food sensitivity.

Hubbard EJ.

Curr Biol. 2013 Apr 22;23(8):R326-7. doi: 10.1016/j.cub.2013.03.034.


Physiological control of germline development.

Hubbard EJ, Korta DZ, Dalfó D.

Adv Exp Med Biol. 2013;757:101-31. doi: 10.1007/978-1-4614-4015-4_5. Review.


Sensory regulation of the C. elegans germline through TGF-β-dependent signaling in the niche.

Dalfó D, Michaelson D, Hubbard EJ.

Curr Biol. 2012 Apr 24;22(8):712-9. doi: 10.1016/j.cub.2012.02.064. Epub 2012 Apr 5.


S6K links cell fate, cell cycle and nutrient response in C. elegans germline stem/progenitor cells.

Korta DZ, Tuck S, Hubbard EJ.

Development. 2012 Mar;139(5):859-70. doi: 10.1242/dev.074047. Epub 2012 Jan 25. Erratum in: Development. 2014 Jan;141(1):236.


A model of stem cell population dynamics: in silico analysis and in vivo validation.

Setty Y, Dalfó D, Korta DZ, Hubbard EJ, Kugler H.

Development. 2012 Jan;139(1):47-56. doi: 10.1242/dev.067512.


Insulin and germline proliferation in Caenorhabditis elegans.

Hubbard EJ.

Vitam Horm. 2011;87:61-77. doi: 10.1016/B978-0-12-386015-6.00024-X. Review.


Soma-germline interactions that influence germline proliferation in Caenorhabditis elegans.

Korta DZ, Hubbard EJ.

Dev Dyn. 2010 May;239(5):1449-59. doi: 10.1002/dvdy.22268. Review.


Clock drawing test ratings by dementia specialists: interrater reliability and diagnostic accuracy.

Nair AK, Gavett BE, Damman M, Dekker W, Green RC, Mandel A, Auerbach S, Steinberg E, Hubbard EJ, Jefferson A, Stern RA.

J Neuropsychiatry Clin Neurosci. 2010 Winter;22(1):85-92. doi: 10.1176/appi.neuropsych.22.1.85.


Insulin signaling promotes germline proliferation in C. elegans.

Michaelson D, Korta DZ, Capua Y, Hubbard EJ.

Development. 2010 Feb;137(4):671-80. doi: 10.1242/dev.042523. Erratum in: Development. 2014 Jan;141(1):237.


A "latent niche" mechanism for tumor initiation.

McGovern M, Voutev R, Maciejowski J, Corsi AK, Hubbard EJ.

Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11617-22. doi: 10.1073/pnas.0903768106. Epub 2009 Jun 29.


MSP and GLP-1/Notch signaling coordinately regulate actomyosin-dependent cytoplasmic streaming and oocyte growth in C. elegans.

Nadarajan S, Govindan JA, McGovern M, Hubbard EJ, Greenstein D.

Development. 2009 Jul;136(13):2223-34. doi: 10.1242/dev.034603.


Characterization of the Caenorhabditis elegans Islet LIM-homeodomain ortholog, lim-7.

Voutev R, Keating R, Hubbard EJ, Vallier LG.

FEBS Lett. 2009 Jan 22;583(2):456-64. doi: 10.1016/j.febslet.2008.12.046. Epub 2008 Dec 29.


A "FLP-Out" system for controlled gene expression in Caenorhabditis elegans.

Voutev R, Hubbard EJ.

Genetics. 2008 Sep;180(1):103-19. doi: 10.1534/genetics.108.090274. Epub 2008 Aug 24.


A scenario-based approach to modeling development: a prototype model of C. elegans vulval fate specification.

Kam N, Kugler H, Marelly R, Appleby L, Fisher J, Pnueli A, Harel D, Stern MJ, Hubbard EJ.

Dev Biol. 2008 Nov 1;323(1):1-5. doi: 10.1016/j.ydbio.2008.07.030. Epub 2008 Jul 31.


Toward verified biological models.

Sadot A, Fisher J, Barak D, Admanit Y, Stern MJ, Hubbard EJ, Harel D.

IEEE/ACM Trans Comput Biol Bioinform. 2008 Apr-Jun;5(2):223-34. doi: 10.1109/TCBB.2007.1076.


Clock drawing performance in cognitively normal elderly.

Hubbard EJ, Santini V, Blankevoort CG, Volkers KM, Barrup MS, Byerly L, Chaisson C, Jefferson AL, Kaplan E, Green RC, Stern RA.

Arch Clin Neuropsychol. 2008 May;23(3):295-327. doi: 10.1016/j.acn.2007.12.003. Epub 2008 Feb 19.


Introduction to the germ line.

Hubbard EJ, Greenstein D.

WormBook. 2005 Sep 1:1-4. Review. No abstract available.


Caenorhabditis elegans germ line: a model for stem cell biology.

Hubbard EJ.

Dev Dyn. 2007 Dec;236(12):3343-57. Review.


Alterations in ribosome biogenesis cause specific defects in C. elegans hermaphrodite gonadogenesis.

Voutev R, Killian DJ, Ahn JH, Hubbard EJ.

Dev Biol. 2006 Oct 1;298(1):45-58. Epub 2006 Jun 8.


Quantitative analysis of germline mitosis in adult C. elegans.

Maciejowski J, Ugel N, Mishra B, Isopi M, Hubbard EJ.

Dev Biol. 2006 Apr 1;292(1):142-51. Epub 2006 Feb 15.


Autosomal genes of autosomal/X-linked duplicated gene pairs and germ-line proliferation in Caenorhabditis elegans.

Maciejowski J, Ahn JH, Cipriani PG, Killian DJ, Chaudhary AL, Lee JI, Voutev R, Johnsen RC, Baillie DL, Gunsalus KC, Fitch DH, Hubbard EJ.

Genetics. 2005 Apr;169(4):1997-2011. Epub 2005 Jan 31.


Computational insights into Caenorhabditis elegans vulval development.

Fisher J, Piterman N, Hubbard EJ, Stern MJ, Harel D.

Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):1951-6. Epub 2005 Jan 31.


A sense of life: computational and experimental investigations with models of biochemical and evolutionary processes.

Mishra B, Daruwala RS, Zhou Y, Ugel N, Policriti A, Antoniotti M, Paxia S, Rejali M, Rudra A, Cherepinsky V, Silver N, Casey W, Piazza C, Simeoni M, Barbano P, Spivak M, Feng J, Gill O, Venkatesh M, Cheng F, Sun B, Ioniata I, Anantharaman T, Hubbard EJ, Pnueli A, Harel D, Chandru V, Hariharan R, Wigler M, Park F, Lin SC, Lazebnik Y, Winkler F, Cantor CR, Carbone A, Gromov M.

OMICS. 2003 Fall;7(3):253-68.


A germ-cell odyssey: fate, survival, migration, stem cells and differentiation. Meeting on germ cells.

Hubbard EJ, Pera RA.

EMBO Rep. 2003 Apr;4(4):352-7. Epub 2003 Mar 21. Review. No abstract available.


The Caenorhabditis elegans gonad: a test tube for cell and developmental biology.

Hubbard EJ, Greenstein D.

Dev Dyn. 2000 May;218(1):2-22. Review.


Evidence for functional and physical association between Caenorhabditis elegans SEL-10, a Cdc4p-related protein, and SEL-12 presenilin.

Wu G, Hubbard EJ, Kitajewski JK, Greenwald I.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15787-91.


Evidence for physical and functional association between EMB-5 and LIN-12 in Caenorhabditis elegans.

Hubbard EJ, Dong Q, Greenwald I.

Science. 1996 Jul 5;273(5271):112-5.


Prescribing patterns of antilipemic drugs and prevalence of hypercholesterolemia in the Nova Scotia population more than 65 years old.

Sketris IS, Kephart GC, Hicks VA, Hubbard EJ, Brown MG, Chandler RF, MacLean DR.

Ann Pharmacother. 1995 Jun;29(6):576-81.


A protein kinase substrate identified by the two-hybrid system.

Yang X, Hubbard EJ, Carlson M.

Science. 1992 Jul 31;257(5070):680-2.


Yeast casein kinase I homologues: an essential gene pair.

Robinson LC, Hubbard EJ, Graves PR, DePaoli-Roach AA, Roach PJ, Kung C, Haas DW, Hagedorn CH, Goebl M, Culbertson MR, et al.

Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):28-32.


Assessing potential predisposition of elementary school children to heart disease.

Crow TA, Brown R, Hubbard EJ, Copeland LR.

J Sch Health. 1982 Dec;52(10):601-4.


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