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Items: 1 to 50 of 269

1.

"There I Was": A Cup of Improvisation.

Hubbard B, Freeman C.

J Spec Oper Med. Winter 2019;19(4):120-122. No abstract available.

PMID:
31910487
2.

Seawater softening of suture zones inhibits fracture propagation in Antarctic ice shelves.

Kulessa B, Booth AD, O'Leary M, McGrath D, King EC, Luckman AJ, Holland PR, Jansen D, Bevan SL, Thompson SS, Hubbard B.

Nat Commun. 2019 Dec 2;10(1):5491. doi: 10.1038/s41467-019-13539-x.

3.

Supraglacial lake drainage at a fast-flowing Greenlandic outlet glacier.

Chudley TR, Christoffersen P, Doyle SH, Bougamont M, Schoonman CM, Hubbard B, James MR.

Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25468-25477. doi: 10.1073/pnas.1913685116. Epub 2019 Dec 2.

PMID:
31792177
4.

Differentiating Familial Chylomicronemia Syndrome From Multifactorial Severe Hypertriglyceridemia by Clinical Profiles.

O'Dea LSL, MacDougall J, Alexander VJ, Digenio A, Hubbard B, Arca M, Moriarty PM, Kastelein JJP, Bruckert E, Soran H, Witztum JL, Hegele RA, Gaudet D.

J Endocr Soc. 2019 Oct 11;3(12):2397-2410. doi: 10.1210/js.2019-00214. eCollection 2019 Dec 1.

5.

Intravitreous Cutaneous Metastatic Melanoma in the Era of Checkpoint Inhibition: Unmasking and Masquerading.

Francis JH, Berry D, Abramson DH, Barker CA, Bergstrom C, Demirci H, Engelbert M, Grossniklaus H, Hubbard B, Iacob CE, Jaben K, Kurli M, Postow MA, Wolchok JD, Kim IK, Wells JR.

Ophthalmology. 2019 Sep 24. pii: S0161-6420(19)32085-8. doi: 10.1016/j.ophtha.2019.09.018. [Epub ahead of print]

PMID:
31708274
6.

From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9.

Petrilli WL, Adam GC, Erdmann RS, Abeywickrema P, Agnani V, Ai X, Baysarowich J, Byrne N, Caldwell JP, Chang W, DiNunzio E, Feng Z, Ford R, Ha S, Huang Y, Hubbard B, Johnston JM, Kavana M, Lisnock JM, Liang R, Lu J, Lu Z, Meng J, Orth P, Palyha O, Parthasarathy G, Salowe SP, Sharma S, Shipman J, Soisson SM, Strack AM, Youm H, Zhao K, Zink DL, Zokian H, Addona GH, Akinsanya K, Tata JR, Xiong Y, Imbriglio JE.

Cell Chem Biol. 2020 Jan 16;27(1):32-40.e3. doi: 10.1016/j.chembiol.2019.10.002. Epub 2019 Oct 22.

PMID:
31653597
7.

Large-scale chemical-genetics yields new M. tuberculosis inhibitor classes.

Johnson EO, LaVerriere E, Office E, Stanley M, Meyer E, Kawate T, Gomez JE, Audette RE, Bandyopadhyay N, Betancourt N, Delano K, Da Silva I, Davis J, Gallo C, Gardner M, Golas AJ, Guinn KM, Kennedy S, Korn R, McConnell JA, Moss CE, Murphy KC, Nietupski RM, Papavinasasundaram KG, Pinkham JT, Pino PA, Proulx MK, Ruecker N, Song N, Thompson M, Trujillo C, Wakabayashi S, Wallach JB, Watson C, Ioerger TR, Lander ES, Hubbard BK, Serrano-Wu MH, Ehrt S, Fitzgerald M, Rubin EJ, Sassetti CM, Schnappinger D, Hung DT.

Nature. 2019 Jul;571(7763):72-78. doi: 10.1038/s41586-019-1315-z. Epub 2019 Jun 19.

PMID:
31217586
8.

Improvised Inguinal Junctional Tourniquets: Recommendations From the Special Operations Combat Medical Skills Sustainment Course.

Kerr W, Hubbard B, Anderson B, Montgomery HR, Glassberg E, King DR, Hardin RD Jr, Knight RM, Cunningham CW.

J Spec Oper Med. 2019 Summer;19(2):128-133.

PMID:
31201768
9.

Physical Conditions of Fast Glacier Flow: 3. Seasonally-Evolving Ice Deformation on Store Glacier, West Greenland.

Young TJ, Christoffersen P, Doyle SH, Nicholls KW, Stewart CL, Hubbard B, Hubbard A, Lok LB, Brennan PV, Benn DI, Luckman A, Bougamont M.

J Geophys Res Earth Surf. 2019 Jan;124(1):245-267. doi: 10.1029/2018JF004821. Epub 2019 Jan 30.

10.

Tripeptide IRW initiates differentiation in osteoblasts differentiation via the RUNX2 pathway.

Shang N, Bhullar KS, Hubbard BP, Wu J.

Biochim Biophys Acta Gen Subj. 2019 Jun;1863(6):1138-1146. doi: 10.1016/j.bbagen.2019.04.007. Epub 2019 Apr 10.

PMID:
30980895
11.

Achieving Aesthetic Results in the Umbilical Float Mini-Abdominoplasty: Patient Selection and Surgical Technique.

Wan D, Hubbard BA, Byrd HS.

Plast Reconstr Surg. 2019 Mar;143(3):722-732. doi: 10.1097/PRS.0000000000005387.

PMID:
30817642
12.

Using Small-Molecule Adjuvants to Repurpose Azithromycin for Use against Pseudomonas aeruginosa.

Hubble VB, Hubbard BA, Minrovic BM, Melander RJ, Melander C.

ACS Infect Dis. 2019 Jan 11;5(1):141-151. doi: 10.1021/acsinfecdis.8b00288. Epub 2018 Nov 29.

13.

Polythermal structure of a Himalayan debris-covered glacier revealed by borehole thermometry.

Miles KE, Hubbard B, Quincey DJ, Miles ES, Sherpa TC, Rowan AV, Doyle SH.

Sci Rep. 2018 Nov 14;8(1):16825. doi: 10.1038/s41598-018-34327-5.

14.

Safety of catheter-based radiofrequency renal denervation on branch renal arteries in a porcine model.

Sakaoka A, Rousselle SD, Hagiwara H, Tellez A, Hubbard B, Sakakura K.

Catheter Cardiovasc Interv. 2019 Feb 15;93(3):494-502. doi: 10.1002/ccd.27953. Epub 2018 Nov 8.

15.

Discovery of heterocyclic replacements for the coumarin core of anti-tubercular FadD32 inhibitors.

Fang C, Lee KK, Nietupski R, Bates RH, Fernandez-Menendez R, Lopez-Roman EM, Guijarro-Lopez L, Yin Y, Peng Z, Gomez JE, Fisher S, Barros-Aguirre D, Hubbard BK, Serrano-Wu MH, Hung DT.

Bioorg Med Chem Lett. 2018 Dec 1;28(22):3529-3533. doi: 10.1016/j.bmcl.2018.09.037. Epub 2018 Sep 29.

16.

Is exon 8 the most critical or the only dispensable exon of the VCAN gene? Insights into VCAN variants and clinical spectrum of Wagner syndrome.

Ankala A, Jain N, Hubbard B, Alexander JJ, Shankar SP.

Am J Med Genet A. 2018 Aug;176(8):1778-1783. doi: 10.1002/ajmg.a.38855. Epub 2018 Jul 28.

PMID:
30055036
17.

Procedural and anatomical predictors of renal denervation efficacy using two radiofrequency renal denervation catheters in a porcine model.

Wolf M, Hubbard B, Sakaoka A, Rousselle S, Tellez A, Jiang X, Kario K, Hohl M, Böhm M, Mahfoud F.

J Hypertens. 2018 Dec;36(12):2453-2459. doi: 10.1097/HJH.0000000000001840.

18.

Conservation of Mannan Synthesis in Fungi of the Zygomycota and Ascomycota Reveals a Broad Diagnostic Target.

Burnham-Marusich AR, Hubbard B, Kvam AJ, Gates-Hollingsworth M, Green HR, Soukup E, Limper AH, Kozel TR.

mSphere. 2018 May 2;3(3). pii: e00094-18. doi: 10.1128/mSphere.00094-18. eCollection 2018 May-Jun.

19.

IL-13 is produced by tumor cells in breast implant-associated anaplastic large cell lymphoma: implications for pathogenesis.

Kadin ME, Morgan J, Xu H, Epstein AL, Sieber D, Hubbard BA, Adams WP Jr, Bacchi CE, Goes JCS, Clemens MW, Medeiros LJ, Miranda RN.

Hum Pathol. 2018 Aug;78:54-62. doi: 10.1016/j.humpath.2018.04.007. Epub 2018 Apr 22.

PMID:
29689246
20.

Incorporation of bridged nucleic acids into CRISPR RNAs improves Cas9 endonuclease specificity.

Cromwell CR, Sung K, Park J, Krysler AR, Jovel J, Kim SK, Hubbard BP.

Nat Commun. 2018 Apr 13;9(1):1448. doi: 10.1038/s41467-018-03927-0.

21.

Identification and Characterization of Novel Receptor-Interacting Serine/Threonine-Protein Kinase 2 Inhibitors Using Structural Similarity Analysis.

Salla M, Aguayo-Ortiz R, Danmaliki GI, Zare A, Said A, Moore J, Pandya V, Manaloor R, Fong S, Blankstein AR, Gibson SB, Garcia LR, Meier P, Bhullar KS, Hubbard BP, Fiteh Y, Vliagoftis H, Goping IS, Brocks D, Hwang P, Velázquez-Martínez CA, Baksh S.

J Pharmacol Exp Ther. 2018 May;365(2):354-367. doi: 10.1124/jpet.117.247163. Epub 2018 Mar 19.

PMID:
29555876
22.

Adult Male With Chest Pain After a Fall.

Nanda S, Madhok M, Hubbard B.

Ann Emerg Med. 2018 Mar;71(3):429-436. doi: 10.1016/j.annemergmed.2017.09.029. No abstract available.

PMID:
29458804
23.

Kinase-targeted cancer therapies: progress, challenges and future directions.

Bhullar KS, Lagarón NO, McGowan EM, Parmar I, Jha A, Hubbard BP, Rupasinghe HPV.

Mol Cancer. 2018 Feb 19;17(1):48. doi: 10.1186/s12943-018-0804-2. Review.

24.

Implementation of a Novel Algorithm to Decrease Unnecessary Hospitalizations in Patients Presenting to a Community Emergency Department With Atrial Fibrillation.

DeMeester S, Hess RA, Hubbard B, LeClerc K, Ferraro J, Albright JJ.

Acad Emerg Med. 2018 Jun;25(6):641-649. doi: 10.1111/acem.13383. Epub 2018 Feb 28.

25.

What Actions Are Health Departments Taking to Improve Safe Drinking Water Programs?

Lamers V, Hubbard BC.

J Environ Health. 2017 Mar;79(7):38-40. No abstract available.

PMID:
29144111
26.

CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects.

Thomas T, Zhou H, Karmally W, Ramakrishnan R, Holleran S, Liu Y, Jumes P, Wagner JA, Hubbard B, Previs SF, Roddy T, Johnson-Levonas AO, Gutstein DE, Marcovina SM, Rader DJ, Ginsberg HN, Millar JS, Reyes-Soffer G.

Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1770-1775. doi: 10.1161/ATVBAHA.117.309549. Epub 2017 Jul 20.

27.

Discovery of an Orally Bioavailable Benzimidazole Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor That Suppresses Body Weight Gain in Diet-Induced Obese Dogs and Postprandial Triglycerides in Humans.

Nakajima K, Chatelain R, Clairmont KB, Commerford R, Coppola GM, Daniels T, Forster CJ, Gilmore TA, Gong Y, Jain M, Kanter A, Kwak Y, Li J, Meyers CD, Neubert AD, Szklennik P, Tedesco V, Thompson J, Truong D, Yang Q, Hubbard BK, Serrano-Wu MH.

J Med Chem. 2017 Jun 8;60(11):4657-4664. doi: 10.1021/acs.jmedchem.7b00173. Epub 2017 May 24.

PMID:
28498655
28.

Correspondence.

Todorich B, Thanos A, Yonekawa Y, Thomas BJ, Faia LJ, Chang E, Shulman J, Olsen KR, Blair MP, Shapiro MP, Ferrone P, Vajzovic L, Toth CA, Lee TC, Robinson J, Hubbard B, Kondo H, Besirli CG, Nudleman E, Wong SC, Kusaka S, Walsh M, Chan RVP, Berrocal A, Caputo G, Murray TG, Sears J, Schunemann R, Harper CA 3rd, Kychental A, Dorta P, Cernichiaro-Espinosa LA, Wu WC, Campbell JP, Martinez-Castellanos MA, Quiroz-Mercado H, Hayashi H, Quiram P, Amphornphruet A, Hartnett ME, Tsui I, Ells A, John V, Moshfeghi D, Capone A Jr, Drenser KA, Trese MT.

Retina. 2017 May;37(5):e52-e54. doi: 10.1097/IAE.0000000000001602. No abstract available.

29.

A conserved NAD+ binding pocket that regulates protein-protein interactions during aging.

Li J, Bonkowski MS, Moniot S, Zhang D, Hubbard BP, Ling AJ, Rajman LA, Qin B, Lou Z, Gorbunova V, Aravind L, Steegborn C, Sinclair DA.

Science. 2017 Mar 24;355(6331):1312-1317. doi: 10.1126/science.aad8242.

30.

Lessons From an Outbreak of Legionnaires' Disease on a Hematology-Oncology Unit.

Francois Watkins LK, Toews KE, Harris AM, Davidson S, Ayers-Millsap S, Lucas CE, Hubbard BC, Kozak-Muiznieks NA, Khan E, Kutty PK.

Infect Control Hosp Epidemiol. 2017 Mar;38(3):306-313. doi: 10.1017/ice.2016.281. Epub 2016 Dec 6.

31.

Systemic AAV9 gene therapy improves the lifespan of mice with Niemann-Pick disease, type C1.

Chandler RJ, Williams IM, Gibson AL, Davidson CD, Incao AA, Hubbard BT, Porter FD, Pavan WJ, Venditti CP.

Hum Mol Genet. 2017 Jan 1;26(1):52-64. doi: 10.1093/hmg/ddw367.

32.

Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor.

Garvie CW, Fraley CV, Elowe NH, Culyba EK, Lemke CT, Hubbard BK, Kaushik VK, Daniels DS.

Protein Sci. 2016 Nov;25(11):2018-2027. doi: 10.1002/pro.3019. Epub 2016 Oct 15.

33.

JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks.

Van Meter M, Simon M, Tombline G, May A, Morello TD, Hubbard BP, Bredbenner K, Park R, Sinclair DA, Bohr VA, Gorbunova V, Seluanov A.

Cell Rep. 2016 Sep 6;16(10):2641-2650. doi: 10.1016/j.celrep.2016.08.006. Epub 2016 Aug 25.

34.

Synthesis and Assay of SIRT1-Activating Compounds.

Dai H, Ellis JL, Sinclair DA, Hubbard BP.

Methods Enzymol. 2016;574:213-244. doi: 10.1016/bs.mie.2016.01.012. Epub 2016 Feb 9.

35.

A Perspective on the Delivery of Renal Denervation Therapy Based on Pre-Clinical Data.

Tellez A, Dillon KN, Hubbard B, Brady DA, Shanmuganayagam D, Rousselle SD.

JACC Basic Transl Sci. 2016 Jun 27;1(4):288-295. doi: 10.1016/j.jacbts.2016.03.010. eCollection 2016 Jun. Review. No abstract available.

36.

Massive subsurface ice formed by refreezing of ice-shelf melt ponds.

Hubbard B, Luckman A, Ashmore DW, Bevan S, Kulessa B, Kuipers Munneke P, Philippe M, Jansen D, Booth A, Sevestre H, Tison JL, O'Leary M, Rutt I.

Nat Commun. 2016 Jun 10;7:11897. doi: 10.1038/ncomms11897.

37.

Tucked Away: An Infected Thrombus.

Hubbard E, Wise E, Hubbard B, Girard S, Kong B, Moudgal V.

Am J Med. 2016 Jun;129(6):576-9. doi: 10.1016/j.amjmed.2016.01.042. Epub 2016 Feb 19. No abstract available.

PMID:
26901112
39.

Fibronectin Fiber Extension Decreases Cell Spreading and Migration.

Hubbard B, Buczek-Thomas JA, Nugent MA, Smith ML.

J Cell Physiol. 2016 Aug;231(8):1728-36. doi: 10.1002/jcp.25271. Epub 2015 Dec 28.

PMID:
26621030
40.

Discovery and Pharmacology of a Novel Class of Diacylglycerol Acyltransferase 2 Inhibitors.

Imbriglio JE, Shen DM, Liang R, Marby K, You M, Youm HW, Feng Z, London C, Xiong Y, Tata J, Verras A, Garcia-Calvo M, Song X, Addona GH, McLaren DG, He T, Murphy B, Metzger DE, Salituro G, Deckman D, Chen Q, Jin X, Stout SJ, Wang SP, Wilsie L, Palyha O, Han S, Hubbard BK, Previs SF, Pinto S, Taggart A.

J Med Chem. 2015 Dec 10;58(23):9345-53. doi: 10.1021/acs.jmedchem.5b01345. Epub 2015 Nov 20.

PMID:
26561979
41.

Effect of Error Propagation in Stable Isotope Tracer Studies: An Approach for Estimating Impact on Apparent Biochemical Flux.

Previs SF, Herath K, Castro-Perez J, Mahsut A, Zhou H, McLaren DG, Shah V, Rohm RJ, Stout SJ, Zhong W, Wang SP, Johns DG, Hubbard BK, Cleary MA, Roddy TP.

Methods Enzymol. 2015;561:331-58. doi: 10.1016/bs.mie.2015.06.021. Epub 2015 Aug 19. Review.

PMID:
26358910
42.

Continuous directed evolution of DNA-binding proteins to improve TALEN specificity.

Hubbard BP, Badran AH, Zuris JA, Guilinger JP, Davis KM, Chen L, Tsai SQ, Sander JD, Joung JK, Liu DR.

Nat Methods. 2015 Oct;12(10):939-42. doi: 10.1038/nmeth.3515. Epub 2015 Aug 10.

43.

Characterization of retentive capacity of the subpericranial pocket in cochlear implants with and without a pedestal.

Papsin BC, Cushing SL, Hubbard BJ, Wong DD, Gordon KA.

Laryngoscope. 2016 May;126(5):1175-9. doi: 10.1002/lary.25502. Epub 2015 Jul 30.

PMID:
26228313
44.

Treatment of Obese Insulin-Resistant Mice With an Allosteric MAPKAPK2/3 Inhibitor Lowers Blood Glucose and Improves Insulin Sensitivity.

Ozcan L, Xu X, Deng SX, Ghorpade DS, Thomas T, Cremers S, Hubbard B, Serrano-Wu MH, Gaestel M, Landry DW, Tabas I.

Diabetes. 2015 Oct;64(10):3396-405. doi: 10.2337/db14-1945. Epub 2015 Jun 11.

45.

Neuromatous regeneration as a nerve response after catheter-based renal denervation therapy in a large animal model: immunohistochemical study.

Rousselle SD, Brants IK, Sakaoka A, Hubbard B, Jackson ND, Wicks JR, Dillon KN, Naiche LA, Hart R, Garza JA, Tellez A.

Circ Cardiovasc Interv. 2015 May;8(5). pii: e002293. doi: 10.1161/CIRCINTERVENTIONS.114.002293.

PMID:
25940523
46.

A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1.

Clifton MC, Dranow DM, Leed A, Fulroth B, Fairman JW, Abendroth J, Atkins KA, Wallace E, Fan D, Xu G, Ni ZJ, Daniels D, Van Drie J, Wei G, Burgin AB, Golub TR, Hubbard BK, Serrano-Wu MH.

PLoS One. 2015 Apr 24;10(4):e0125010. doi: 10.1371/journal.pone.0125010. eCollection 2015.

47.

Session 1.5: other viral clearance and inactivation approaches (multimodal chromatography, membrane chromatography, chemical precipitation).

Hubbard B.

PDA J Pharm Sci Technol. 2015 Jan-Feb;69(1):173-82. doi: 10.5731/pdajpst.2015.01041. Review. No abstract available.

PMID:
25691725
48.

Lifespan and healthspan extension by resveratrol.

Bhullar KS, Hubbard BP.

Biochim Biophys Acta. 2015 Jun;1852(6):1209-18. doi: 10.1016/j.bbadis.2015.01.012. Epub 2015 Jan 29. Review.

49.

Dynamics of impurity attraction and repulsion of an intrinsic localized mode in a driven 1-D cantilever array.

Sato M, Sada Y, Shi W, Shige S, Ishikawa T, Soga Y, Hubbard BE, Ilic B, Sievers AJ.

Chaos. 2015 Jan;25(1):013103. doi: 10.1063/1.4905254.

PMID:
25637914
50.

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