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Attenuation of NAD[P]H:quinone oxidoreductase 1 aggravates prostate cancer and tumor cell plasticity through enhanced TGFβ signaling.

Thapa D, Huang SB, Muñoz AR, Yang X, Bedolla RG, Hung CN, Chen CL, Huang TH, Liss MA, Reddick RL, Miyamoto H, Kumar AP, Ghosh R.

Commun Biol. 2020 Jan 3;3(1):12. doi: 10.1038/s42003-019-0720-z.


Attenuation of NAD[P]H:quinone oxidoreductase 1 aggravates prostate cancer and tumor cell plasticity through enhanced TGFβ signaling.

Thapa D, Huang SB, Muñoz AR, Yang X, Bedolla RG, Hung CN, Chen CL, Huang TH, Liss MA, Reddick RL, Miyamoto H, Kumar AP, Ghosh R.

Commun Biol. 2020 Jan 3;3:12. doi: 10.1038/s42003-019-0720-z. eCollection 2020.


Treatment of atopic dermatitis with dupilumab in Taiwan: dynamic changes of IgE levels as a potential response biomarker.

Huang TH, Chen YC, Lin SY, Chiu SH, Yang TT, Chiu LW, Chen YY, Lan CE.

Eur J Dermatol. 2019 Dec 1;29(6):658-659. doi: 10.1684/ejd.2019.3661. No abstract available.


Enhanced risk of traumatic brain injury in patients with chronic obstructive pulmonary disease.

Huang TH, Chen CZ, Kuo HI, Er HP, Lin SH.

J Investig Med. 2019 Dec 31. pii: jim-2019-001207. doi: 10.1136/jim-2019-001207. [Epub ahead of print]


Factors Associated with Spiritual Care Competencies in Taiwan's Clinical Nurses: A Descriptive Correlational Study.

Hsieh SI, Hsu LL, Kao CY, Breckenridge-Sproat S, Lin HL, Tai HC, Huang TH, Chu TL.

J Clin Nurs. 2019 Dec 19. doi: 10.1111/jocn.15141. [Epub ahead of print]


Coenzyme Q0 From Antrodia cinnamomea Exhibits Drug-Resistant Bacteria Eradication and Keratinocyte Inflammation Mitigation to Ameliorate Infected Atopic Dermatitis in Mouse.

Chou WL, Lee TH, Huang TH, Wang PW, Chen YP, Chen CC, Chang ZY, Fang JY, Yang SC.

Front Pharmacol. 2019 Dec 3;10:1445. doi: 10.3389/fphar.2019.01445. eCollection 2019.


Spatial EGFR Dynamics and Metastatic Phenotypes Modulated by Upregulated EphB2 and Src Pathways in Advanced Prostate Cancer.

Liu YL, Horning AM, Lieberman B, Kim M, Lin CK, Hung CN, Chou CW, Wang CM, Lin CL, Kirma NB, Liss MA, Vasisht R, Perillo EP, Blocher K, Horng H, Taverna JA, Ruan J, Yankeelov TE, Dunn AK, Huang TH, Yeh HC, Chen CL.

Cancers (Basel). 2019 Dec 1;11(12). pii: E1910. doi: 10.3390/cancers11121910.


Real-Time Evaluation of the Mechanical Performance and Residual Life of a Notching Mold using Embedded PVDF Sensors and SVM Criteria.

Chang CY, Huang TH, Chung TC.

Sensors (Basel). 2019 Nov 22;19(23). pii: E5123. doi: 10.3390/s19235123.


The effects of a 226-km ironman triathlon race on bone turnover in amateur male triathletes.

Wu CC, Huang TH.

J Sports Med Phys Fitness. 2019 Oct;59(10):1709-1715. doi: 10.23736/S0022-4707.19.09564-1.


Osteonecrosis (Avascular Necrosis) of Knee and Tibia.

Huang TH, Liu HC, Yeh TC, Hou JY, Lin CY.

J Pediatr. 2019 Nov 1. pii: S0022-3476(19)31330-7. doi: 10.1016/j.jpeds.2019.10.009. [Epub ahead of print] No abstract available.


Changes in riverine organic carbon input to the ocean from mainland China over the past 60 years.

Liu D, Bai Y, He X, Chen CA, Huang TH, Pan D, Chen X, Wang D, Zhang L.

Environ Int. 2020 Jan;134:105258. doi: 10.1016/j.envint.2019.105258. Epub 2019 Oct 31.


Development of a multiplex and sensitive lateral flow immunoassay for the diagnosis of periprosthetic joint infection.

Tsai TT, Huang TH, Ho NY, Chen YP, Chen CA, Chen CF.

Sci Rep. 2019 Oct 30;9(1):15679. doi: 10.1038/s41598-019-52051-6.


In silico identification of thiostrepton as an inhibitor of cancer stem cell growth and an enhancer for chemotherapy in non-small-cell lung cancer.

Huang TH, Wu ATH, Cheng TS, Lin KT, Lai CJ, Hsieh HW, Chang PM, Wu CW, Huang CF, Chen KY.

J Cell Mol Med. 2019 Dec;23(12):8184-8195. doi: 10.1111/jcmm.14689. Epub 2019 Oct 22.


Differences in neurocognitive performance and metabolic and inflammatory indices in male adults with obesity as a function of regular exercise.

Tsai CL, Pan CY, Chen FC, Huang TH, Tsai MC, Chuang CY.

Exp Physiol. 2019 Nov;104(11):1650-1660. doi: 10.1113/EP087862. Epub 2019 Oct 14.


Xenografting of human umbilical mesenchymal stem cells from Wharton's jelly ameliorates mouse spinocerebellar ataxia type 1.

Tsai PJ, Yeh CC, Huang WJ, Min MY, Huang TH, Ko TL, Huang PY, Chen TH, Hsu SPC, Soong BW, Fu YS.

Transl Neurodegener. 2019 Sep 5;8:29. doi: 10.1186/s40035-019-0166-8. eCollection 2019.


Cutaneous delivery of [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol, an indole-3-carbinol derivative, mitigates psoriasiform lesion by blocking MAPK/NF-κB/AP-1 activation.

Weng JR, Huang TH, Lin ZC, Alalaiwe A, Fang JY.

Biomed Pharmacother. 2019 Nov;119:109398. doi: 10.1016/j.biopha.2019.109398. Epub 2019 Sep 5.


Positive Effects of Ger-Gen-Chyn-Lian-Tang on Cholestatic Liver Fibrosis in Bile Duct Ligation-Challenged Mice.

Chang ZY, Chen CC, Liu HM, Yeh YC, Lin TY, Lee TY, Huang TH.

Int J Mol Sci. 2019 Aug 26;20(17). pii: E4181. doi: 10.3390/ijms20174181.


Removal of fine particles from IC chip carbonization process in a rotating packed bed: Modeling and assessment.

Chen TL, Huang TH, Hsu CH, Chen YH, Pan SY, Chiang PC.

Chemosphere. 2020 Jan;238:124600. doi: 10.1016/j.chemosphere.2019.124600. Epub 2019 Aug 17.


Empowering therapeutic antibodies with IFN-α for cancer immunotherapy.

Guo J, Xiao Y, Iyer R, Lu X, Lake M, Ladror U, Harlan J, Samanta T, Tomlinson M, Bukofzer G, Donawho C, Shoemaker A, Huang TH.

PLoS One. 2019 Aug 8;14(8):e0219829. doi: 10.1371/journal.pone.0219829. eCollection 2019.


[Effect and mechanism of adipocyte co-culture on aquaporin-9 expression in HepG2 cells].

Huang TH, Li CF, Qiu LW, Liao ST, Mei ZC.

Zhonghua Gan Zang Bing Za Zhi. 2019 Jun 20;27(6):450-456. doi: 10.3760/cma.j.issn.1007-3418.2019.06.012. Chinese.


Prostate Health Index outperforms other PSA derivatives in predicting a positive biopsy in men with tPSA <10 ng/mL: Largest prospective cohort in Taiwan.

Fan YH, Pan PH, Lin TP, Huang TH, Wei TC, Huang IS, Lin CC, Huang EYH, Chung HJ, Huang WJS.

J Chin Med Assoc. 2019 Oct;82(10):772-777. doi: 10.1097/JCMA.0000000000000160.


Antrodia cinnamomea Enhances Chemo-Sensitivity of 5-FU and Suppresses Colon Tumorigenesis and Cancer Stemness via Up-Regulation of Tumor Suppressor miR-142-3p.

Huang YJ, Yadav VK, Srivastava P, Wu AT, Huynh TT, Wei PL, Huang CF, Huang TH.

Biomolecules. 2019 Jul 25;9(8). pii: E306. doi: 10.3390/biom9080306.


Identification of Withaferin A as a Potential Candidate for Anti-Cancer Therapy in Non-Small Cell Lung Cancer.

Hsu JH, Chang PM, Cheng TS, Kuo YL, Wu AT, Tran TH, Yang YH, Chen JM, Tsai YC, Chu YS, Huang TH, Huang CF, Lai JM.

Cancers (Basel). 2019 Jul 17;11(7). pii: E1003. doi: 10.3390/cancers11071003.


Efficacy and safety of denosumab therapy for low bone mineral density in childhood cancer survivors: A report of preliminary experience.

Huang TH, Liu HC, Hou JY, Chang CY, Sun FJ, Yeh TC.

Pediatr Blood Cancer. 2019 Oct;66(10):e27927. doi: 10.1002/pbc.27927. Epub 2019 Jul 16.


A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer.

Zhu C, Li L, Zhang Z, Bi M, Wang H, Su W, Hernandez K, Liu P, Chen J, Chen M, Huang TH, Chen L, Liu Z.

Mol Cell. 2019 Aug 22;75(4):791-806.e8. doi: 10.1016/j.molcel.2019.06.010. Epub 2019 Jul 11.


The concurrent treatment of Scutellaria baicalensis Georgi enhances the therapeutic efficacy of cisplatin but also attenuates chemotherapy-induced cachexia and acute kidney injury.

Huang TH, Wu TH, Guo YH, Li TL, Chan YL, Wu CJ.

J Ethnopharmacol. 2019 Oct 28;243:112075. doi: 10.1016/j.jep.2019.112075. Epub 2019 Jul 7.


Image gallery: Fluoroscopy-induced radiation dermatitis.

Huang TH, Hu SC.

Br J Dermatol. 2019 Oct;181(4):e87. doi: 10.1111/bjd.18148. Epub 2019 Jul 9. No abstract available.


Sulfur-Based Intramolecular Hydrogen-Bond: Excited-State Hydrogen-Bond On/Off Switch with Dual Room-Temperature Phosphorescence.

Liu ZY, Hu JW, Huang CH, Huang TH, Chen DG, Ho SY, Chen KY, Li EY, Chou PT.

J Am Chem Soc. 2019 Jun 26;141(25):9885-9894. doi: 10.1021/jacs.9b02765. Epub 2019 Jun 17.


Synergistic effect of combined melatonin and adipose-derived mesenchymal stem cell (ADMSC)-derived exosomes on amelioration of dextran sulfate sodium (DSS)-induced acute colitis.

Chang CL, Chen CH, Chiang JY, Sun CK, Chen YL, Chen KH, Sung PH, Huang TH, Li YC, Chen HH, Yip HK.

Am J Transl Res. 2019 May 15;11(5):2706-2724. eCollection 2019.


Depression amongst patients commencing maintenance dialysis is associated with increased risk of death and severe infections: A nationwide cohort study.

Wu PH, Lin MY, Huang TH, Lin YT, Hung CC, Yeh YC, Kuo HT, Chiu YW, Hwang SJ, Tsai JC, Carrero JJ.

PLoS One. 2019 Jun 13;14(6):e0218335. doi: 10.1371/journal.pone.0218335. eCollection 2019.


Substitutions of strontium in bioactive calcium silicate bone cements stimulate osteogenic differentiation in human mesenchymal stem cells.

Huang TH, Kao CT, Shen YF, Lin YT, Liu YT, Yen SY, Ho CC.

J Mater Sci Mater Med. 2019 Jun 4;30(6):68. doi: 10.1007/s10856-019-6274-2.


Pulmonary alveolar proteinosis with upper-lobe predominance in a non-smoking female.

Er HP, Lee CT, Huang TH.

Respirol Case Rep. 2019 May 29;7(6):e00445. doi: 10.1002/rcr2.445. eCollection 2019 Aug.


Apoptotic or Antiproliferative Activity of Natural Products against Keratinocytes for the Treatment of Psoriasis.

Huang TH, Lin CF, Alalaiwe A, Yang SC, Fang JY.

Int J Mol Sci. 2019 May 24;20(10). pii: E2558. doi: 10.3390/ijms20102558. Review.


The therapeutic impact of entresto on protecting against cardiorenal syndrome-associated renal damage in rats on high protein diet.

Yang CC, Chen YT, Chen CH, Li YC, Shao PL, Huang TH, Chen YL, Sun CK, Yip HK.

Biomed Pharmacother. 2019 Aug;116:108954. doi: 10.1016/j.biopha.2019.108954. Epub 2019 May 17.


Exercise Alleviates Osteoporosis in Rats with Mild Chronic Kidney Disease by Decreasing Sclerostin Production.

Liao HW, Huang TH, Chang YH, Liou HH, Chou YH, Sue YM, Hung PH, Chang YT, Ho PC, Tsai KJ.

Int J Mol Sci. 2019 Apr 25;20(8). pii: E2044. doi: 10.3390/ijms20082044.


Post-irradiation recovery time strongly influences fractional laser-facilitated skin absorption.

Lee WR, Hsiao CY, Huang TH, Wang CL, Alalaiwe A, Chen EL, Fang JY.

Int J Pharm. 2019 Jun 10;564:48-58. doi: 10.1016/j.ijpharm.2019.04.043. Epub 2019 Apr 15.


Cyclooxygenase-2 Activity Regulates Recruitment of VEGF-Secreting Ly6Chigh Monocytes in Ventilator-Induced Lung Injury.

Huang TH, Fang PH, Li JM, Ling HY, Lin CM, Shi CS.

Int J Mol Sci. 2019 Apr 10;20(7). pii: E1771. doi: 10.3390/ijms20071771.


East China Sea increasingly gains limiting nutrient P from South China Sea.

Huang TH, Chen CA, Lee J, Wu CR, Wang YL, Bai Y, He X, Wang SL, Kandasamy S, Lou JY, Tsuang BJ, Chen HW, Tseng RS, Yang YJ.

Sci Rep. 2019 Apr 4;9(1):5648. doi: 10.1038/s41598-019-42020-4.


SOX11 hypermethylation as a tumor biomarker in endometrial cancer.

Shan T, Uyar DS, Wang LS, Mutch DG, Huang TH, Rader JS, Sheng X, Huang YW.

Biochimie. 2019 Jul;162:8-14. doi: 10.1016/j.biochi.2019.03.019. Epub 2019 Mar 29.


Lipo-PEG-PEI complex as an intracellular transporter for protein therapeutics.

Lin YL, Chen CH, Liu YK, Huang TH, Tsai NM, Tzou SC, Liao KW.

Int J Nanomedicine. 2019 Feb 13;14:1119-1130. doi: 10.2147/IJN.S188970. eCollection 2019.


In Vivo Rodent Models of Type 2 Diabetes and Their Usefulness for Evaluating Flavonoid Bioactivity.

Fang JY, Lin CH, Huang TH, Chuang SY.

Nutrients. 2019 Feb 28;11(3). pii: E530. doi: 10.3390/nu11030530. Review.


H-reflex in abductor hallucis and postural performance between flexible flatfoot and normal foot.

Huang TH, Chou LW, Huang CY, Wei SW, Tsai YJ, Chen YJ.

Phys Ther Sport. 2019 May;37:27-33. doi: 10.1016/j.ptsp.2019.02.004. Epub 2019 Feb 19.


Malnutrition associated with an increased risk of postoperative complications following hepatectomy in patients with hepatocellular carcinoma.

Huang TH, Hsieh CC, Kuo LM, Chang CC, Chen CH, Chi CC, Liu CH.

HPB (Oxford). 2019 Sep;21(9):1150-1155. doi: 10.1016/j.hpb.2019.01.003. Epub 2019 Feb 11.


Lymph node ratio as prognostic variable in oral squamous cell carcinomas: Systematic review and meta-analysis.

Huang TH, Li KY, Choi WS.

Oral Oncol. 2019 Feb;89:133-143. doi: 10.1016/j.oraloncology.2018.12.032. Epub 2019 Jan 8. Review.


Specific drug delivery efficiently induced human breast tumor regression using a lipoplex by non-covalent association with anti-tumor antibodies.

Lin YL, Tsai NM, Chen CH, Liu YK, Lee CJ, Chan YL, Wang YS, Chang YC, Lin CH, Huang TH, Wang CC, Chi KH, Liao KW.

J Nanobiotechnology. 2019 Feb 6;17(1):25. doi: 10.1186/s12951-019-0457-3.


Anti-inflammatory property of quercetin through downregulation of ICAM-1 and MMP-9 in TNF-α-activated retinal pigment epithelial cells.

Cheng SC, Wu YH, Huang WC, Pang JS, Huang TH, Cheng CY.

Cytokine. 2019 Apr;116:48-60. doi: 10.1016/j.cyto.2019.01.001. Epub 2019 Jan 24.


Aberrant enhancer hypomethylation contributes to hepatic carcinogenesis through global transcriptional reprogramming.

Xiong L, Wu F, Wu Q, Xu L, Cheung OK, Kang W, Mok MT, Szeto LLM, Lun CY, Lung RW, Zhang J, Yu KH, Lee SD, Huang G, Wang CM, Liu J, Yu Z, Yu DY, Chou JL, Huang WH, Feng B, Cheung YS, Lai PB, Tan P, Wong N, Chan MW, Huang TH, Yip KY, Cheng AS, To KF.

Nat Commun. 2019 Jan 18;10(1):335. doi: 10.1038/s41467-018-08245-z.


Long-term Therapeutic Effects of Extracorporeal Shock Wave-Assisted Melatonin Therapy on Mononeuropathic Pain in Rats.

Yang CH, Yip HK, Chen HF, Yin TC, Chiang JY, Sung PH, Lin KC, Tsou YH, Chen YL, Li YC, Huang TH, Huang CR, Luo CW, Chen KH.

Neurochem Res. 2019 Apr;44(4):796-810. doi: 10.1007/s11064-018-02713-0. Epub 2019 Jan 10.


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