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Fluid shear stress induces endothelial cell injury via PKCα-mediated repression of p120-catenin and vascular endothelial cadherin in vitro.

Zhao YY, Huang SX, Hao Z, Zhu HX, Xing ZL, Li MH.

World Neurosurg. 2020 Jan 14. pii: S1878-8750(20)30035-8. doi: 10.1016/j.wneu.2020.01.028. [Epub ahead of print]


Enzymatic synthesis of non-digestible oligosaccharide catalyzed by dextransucrase and dextranase from maltose acceptor reaction.

Huang SX, Hou DZ, Qi PX, Wang Q, Chen HL, Ci LY, Chen S.

Biochem Biophys Res Commun. 2020 Jan 13. pii: S0006-291X(19)32330-7. doi: 10.1016/j.bbrc.2019.12.010. [Epub ahead of print]


Quantitative analysis of straight-chain/branched-chain Ratio During Enzymatic Synthesis of Dextran Based on Periodate Oxidation.

Wang Q, Qi PX, Huang SX, Hou DZ, Xu XD, Ci LY, Chen S.

Biochem Biophys Res Commun. 2020 Jan 11. pii: S0006-291X(20)30026-7. doi: 10.1016/j.bbrc.2020.01.010. [Epub ahead of print]


Benwamycins A-G, Trialkyl-Substituted Benzene Derivatives from a Soil-Derived Streptomyces.

Yang FX, Huang JP, Liu Z, Wang Z, Yang J, Tang J, Yu Z, Yan Y, Kai G, Huang SX.

J Nat Prod. 2020 Jan 6. doi: 10.1021/acs.jnatprod.9b00903. [Epub ahead of print]


Cangumycins A-F, six new angucyclinone analogues with immunosuppressive activity from Streptomyces.

Wang L, Wang L, Zhou Z, Wang YJ, Huang JP, Ma YT, Liu Y, Huang SX.

Chin J Nat Med. 2019 Dec;17(12):982-987. doi: 10.1016/S1875-5364(19)30121-9.


Expression of the small cysteine-rich protein SCR96 from Phytophthora cactorum in mammalian cells: phytotoxicity and exploitation of its polyclonal antibody.

Huang SX, Zhang ZH, Liu W, Tao H, Zhang Y, Shi NX, Zhu F, Ji ZL, Chen XR.

Biotechnol Lett. 2020 Jan;42(1):125-133. doi: 10.1007/s10529-019-02754-7. Epub 2019 Nov 12.


Functional genomics analysis reveals two novel genes required for littorine biosynthesis.

Qiu F, Zeng J, Wang J, Huang JP, Zhou W, Yang C, Lan X, Chen M, Huang SX, Kai G, Liao Z.

New Phytol. 2019 Nov 9. doi: 10.1111/nph.16317. [Epub ahead of print]


Anti-Hepatitis B Virus Activity of Esculetin from Microsorium fortunei In Vitro and In Vivo.

Huang SX, Mou JF, Luo Q, Mo QH, Zhou XL, Huang X, Xu Q, Tan XD, Chen X, Liang CQ.

Molecules. 2019 Sep 25;24(19). pii: E3475. doi: 10.3390/molecules24193475.


Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation.

Huang JP, Fang C, Ma X, Wang L, Yang J, Luo J, Yan Y, Zhang Y, Huang SX.

Nat Commun. 2019 Sep 6;10(1):4036. doi: 10.1038/s41467-019-11987-z.


Vincristine and bortezomib use distinct upstream mechanisms to activate a common SARM1-dependent axon degeneration program.

Geisler S, Doan RA, Cheng GC, Cetinkaya-Fisgin A, Huang SX, Höke A, Milbrandt J, DiAntonio A.

JCI Insight. 2019 Sep 5;4(17). pii: 129920. doi: 10.1172/jci.insight.129920.


Dimeric Pyranonaphthoquinone Glycosides with Anti-HIV and Cytotoxic Activities from a Soil-Derived Streptomyces.

He X, Wang Y, Luo RH, Yang LM, Wang L, Guo D, Yang J, Deng Y, Zheng YT, Huang SX.

J Nat Prod. 2019 Jul 26;82(7):1813-1819. doi: 10.1021/acs.jnatprod.9b00022. Epub 2019 Jul 16.


Severe influenza pneumonitis in children with inherited TLR3 deficiency.

Lim HK, Huang SXL, Chen J, Kerner G, Gilliaux O, Bastard P, Dobbs K, Hernandez N, Goudin N, Hasek ML, García Reino EJ, Lafaille FG, Lorenzo L, Luthra P, Kochetkov T, Bigio B, Boucherit S, Rozenberg F, Vedrinne C, Keller MD, Itan Y, García-Sastre A, Celard M, Orange JS, Ciancanelli MJ, Meyts I, Zhang Q, Abel L, Notarangelo LD, Snoeck HW, Casanova JL, Zhang SY.

J Exp Med. 2019 Sep 2;216(9):2038-2056. doi: 10.1084/jem.20181621. Epub 2019 Jun 19.


A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening.

Getz RA, Kwak G, Cornell S, Mbugua S, Eberhard J, Huang SX, Abbasi Z, de Medeiros AS, Thomas R, Bukowski B, Dranchak PK, Inglese J, Hoffman CS.

Cell Signal. 2019 Aug;60:114-121. doi: 10.1016/j.cellsig.2019.04.010. Epub 2019 Apr 24.


Phase-field modeling and machine learning of electric-thermal-mechanical breakdown of polymer-based dielectrics.

Shen ZH, Wang JJ, Jiang JY, Huang SX, Lin YH, Nan CW, Chen LQ, Shen Y.

Nat Commun. 2019 Apr 23;10(1):1843. doi: 10.1038/s41467-019-09874-8.


The RXLR Effector PcAvh1 Is Required for Full Virulence of Phytophthora capsici.

Chen XR, Zhang Y, Li HY, Zhang ZH, Sheng GL, Li YP, Xing YP, Huang SX, Tao H, Kuan T, Zhai Y, Ma W.

Mol Plant Microbe Interact. 2019 Aug;32(8):986-1000. doi: 10.1094/MPMI-09-18-0251-R. Epub 2019 Jun 27.


Elucidation of the Herbicidin Tailoring Pathway Offers Insights into Its Structural Diversity.

Pan HX, Chen Z, Zeng T, Jin WB, Geng Y, Lin GM, Zhao J, Li WT, Xiong Z, Huang SX, Zhai X, Liu HW, Tang GL.

Org Lett. 2019 Mar 1;21(5):1374-1378. doi: 10.1021/acs.orglett.9b00066. Epub 2019 Feb 14.


Generation of pulmonary neuroendocrine cells and SCLC-like tumors from human embryonic stem cells.

Chen HJ, Poran A, Unni AM, Huang SX, Elemento O, Snoeck HW, Varmus H.

J Exp Med. 2019 Mar 4;216(3):674-687. doi: 10.1084/jem.20181155. Epub 2019 Feb 8.


Gene therapy targeting SARM1 blocks pathological axon degeneration in mice.

Geisler S, Huang SX, Strickland A, Doan RA, Summers DW, Mao X, Park J, DiAntonio A, Milbrandt J.

J Exp Med. 2019 Feb 4;216(2):294-303. doi: 10.1084/jem.20181040. Epub 2019 Jan 14.


Characterization of the N-methyltransferases involved in the biosynthesis of toxoflavin, fervenulin and reumycin from Streptomyces hiroshimensis ATCC53615.

Su C, Yan Y, Guo X, Luo J, Liu C, Zhang Z, Xiang WS, Huang SX.

Org Biomol Chem. 2019 Jan 16;17(3):477-481. doi: 10.1039/c8ob02847h.


[Uvuplopalatal flap in OSAHS patients with anteriorand posterior pharyngeal plane stenosis].

Jin JH, Huang SX, Liang YY, Cui ZZ.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Dec 5;32(23):1817-1820. doi: 10.13201/j.issn.1001-1781.2018.23.012. Chinese.


New phloroglucinol derivatives with protein tyrosine phosphatase 1B (PTP1B) inhibitory activities from Syzygium austroyunnanense.

Xu SH, Xu W, Wang L, Hu YK, Liu JP, Zhao Y, Li MJ, Li F, Huang SX, Zhao Y.

Fitoterapia. 2018 Nov;131:141-145. doi: 10.1016/j.fitote.2018.10.010. Epub 2018 Oct 10.


3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling.

Zhang Y, Yang Y, Jiang M, Huang SX, Zhang W, Al Alam D, Danopoulos S, Mori M, Chen YW, Balasubramanian R, Chuva de Sousa Lopes SM, Serra C, Bialecka M, Kim E, Lin S, Toste de Carvalho ALR, Riccio PN, Cardoso WV, Zhang X, Snoeck HW, Que J.

Cell Stem Cell. 2018 Oct 4;23(4):516-529.e5. doi: 10.1016/j.stem.2018.08.009. Epub 2018 Sep 20.


New phenoxazinone-related alkaloids from strain Streptomyces sp. KIB-H1318.

Yang FX, Hou GX, Luo J, Yang J, Yan Y, Huang SX.

J Antibiot (Tokyo). 2018 Nov;71(12):1040-1043. doi: 10.1038/s41429-018-0099-y. Epub 2018 Sep 14.


miR-182-5p Promotes Growth in Oral Squamous Cell Carcinoma by Inhibiting CAMK2N1.

Li N, Nan CC, Zhong XY, Weng JQ, Fan HD, Sun HP, Tang S, Shi L, Huang SX.

Cell Physiol Biochem. 2018;49(4):1329-1341. doi: 10.1159/000493411. Epub 2018 Sep 11.


Dopaminergic neurons show increased low-molecular-mass protein 7 activity induced by 6-hydroxydopamine in vitro and in vivo.

Mo MS, Li GH, Sun CC, Huang SX, Wei L, Zhang LM, Zhou MM, Wu ZH, Guo WY, Yang XL, Chen CJ, Qu SG, He JX, Xu PY.

Transl Neurodegener. 2018 Aug 17;7:19. doi: 10.1186/s40035-018-0125-9. eCollection 2018.


Berberine Protects Secondary Injury in Mice with Traumatic Brain Injury Through Anti-oxidative and Anti-inflammatory Modulation.

Huang SX, Qiu G, Cheng FR, Pei Z, Yang Z, Deng XH, Zhu JH, Chen L, Chen CC, Lin WF, Liu Y, Liu Z, Zhu FQ.

Neurochem Res. 2018 Sep;43(9):1814-1825. doi: 10.1007/s11064-018-2597-5. Epub 2018 Jul 19.


Air pollutants and early origins of respiratory diseases.

Kim D, Chen Z, Zhou LF, Huang SX.

Chronic Dis Transl Med. 2018 Jun 7;4(2):75-94. doi: 10.1016/j.cdtm.2018.03.003. eCollection 2018 Jun.


Cytotoxicity-Guided Isolation of Two New Phenolic Derivatives from Dryopteris fragrans (L.) Schott.

Zhang T, Wang L, Duan DH, Zhang YH, Huang SX, Chang Y.

Molecules. 2018 Jul 6;23(7). pii: E1652. doi: 10.3390/molecules23071652.


Myeloid-derived macrophages and secreted HSP90α induce pancreatic ductal adenocarcinoma development.

Chen CC, Chen LL, Li CP, Hsu YT, Jiang SS, Fan CS, Chua KV, Huang SX, Shyr YM, Chen LT, Huang TS.

Oncoimmunology. 2018 Feb 1;7(5):e1424612. doi: 10.1080/2162402X.2018.1424612. eCollection 2018.


Glycosylated piericidins from an endophytic streptomyces with cytotoxicity and antimicrobial activity.

Shang NN, Zhang Z, Huang JP, Wang L, Luo J, Yang J, Peng T, Yan Y, Ma YT, Huang SX.

J Antibiot (Tokyo). 2018 Jul;71(7):672-676. doi: 10.1038/s41429-018-0051-1. Epub 2018 Apr 12.


Identification and functional analysis of the NLP-encoding genes from the phytopathogenic oomycete Phytophthora capsici.

Chen XR, Huang SX, Zhang Y, Sheng GL, Li YP, Zhu F.

Mol Genet Genomics. 2018 Aug;293(4):931-943. doi: 10.1007/s00438-018-1432-7. Epub 2018 Mar 23.


A new actinomycin Z analogue with an additional oxygen bridge between chromophore and β-depsipentapeptide from Streptomyces sp. KIB-H714.

Dong M, Cao P, Ma YT, Luo J, Yan Y, Li RT, Huang SX.

Nat Prod Res. 2019 Jan;33(2):219-225. doi: 10.1080/14786419.2018.1443097. Epub 2018 Mar 2.


β-Catenin maintains lung epithelial progenitors after lung specification.

Ostrin EJ, Little DR, Gerner-Mauro KN, Sumner EA, Ríos-Corzo R, Ambrosio E, Holt SE, Forcioli-Conti N, Akiyama H, Hanash SM, Kimura S, Huang SXL, Chen J.

Development. 2018 Mar 9;145(5). pii: dev160788. doi: 10.1242/dev.160788.


Magnetic properties and structure of tetranuclear lanthanide complexes based on 8-hydroxylquinoline Schiff base derivative and β-diketone coligand.

Gao HL, Huang SX, Zhou XP, Liu Z, Cui JZ.

Dalton Trans. 2018 Mar 6;47(10):3503-3511. doi: 10.1039/c8dt00063h.


Thin films of topological Kondo insulator candidate SmB6: Strong spin-orbit torque without exclusive surface conduction.

Li Y, Ma Q, Huang SX, Chien CL.

Sci Adv. 2018 Jan 19;4(1):eaap8294. doi: 10.1126/sciadv.aap8294. eCollection 2018 Jan.


Transcription profiling and identification of infection-related genes in Phytophthora cactorum.

Chen XR, Huang SX, Zhang Y, Sheng GL, Zhang BY, Li QY, Zhu F, Xu JY.

Mol Genet Genomics. 2018 Apr;293(2):541-555. doi: 10.1007/s00438-017-1400-7. Epub 2017 Dec 7.


New tetralone derivatives from the leaves of Cyclocarya paliurus.

Zhou XL, Luo Q, Huang SX, Wang PC, Xu Q, Huang X, Liang CQ, Chen X.

J Asian Nat Prod Res. 2019 Feb;21(2):157-164. doi: 10.1080/10286020.2017.1409733. Epub 2017 Dec 6.


Bufalin Inhibits Cellular Proliferation and Cancer Stem Cell-Like Phenotypes via Upregulation of MiR-203 in Glioma.

Liu T, Wu C, Weng G, Zhao Z, He X, Fu C, Sui Z, Huang SX.

Cell Physiol Biochem. 2017;44(2):671-681. doi: 10.1159/000485279. Epub 2017 Nov 23.


Lorneic Acid Analogues from an Endophytic Actinomycete.

Yang R, Yang J, Wang L, Huang JP, Xiong Z, Luo J, Yu M, Yan Y, Huang SX.

J Nat Prod. 2017 Oct 27;80(10):2615-2619. doi: 10.1021/acs.jnatprod.7b00056. Epub 2017 Oct 9.


MicroRNAs: A novel potential biomarker for diagnosis and therapy in patients with non-small cell lung cancer.

Zhou Q, Huang SX, Zhang F, Li SJ, Liu C, Xi YY, Wang L, Wang X, He QQ, Sun CC, Li DJ.

Cell Prolif. 2017 Dec;50(6). doi: 10.1111/cpr.12394. Epub 2017 Oct 8. Review.


Functional vascularized lung grafts for lung bioengineering.

Dorrello NV, Guenthart BA, O'Neill JD, Kim J, Cunningham K, Chen YW, Biscotti M, Swayne T, Wobma HM, Huang SXL, Snoeck HW, Bacchetta M, Vunjak-Novakovic G.

Sci Adv. 2017 Aug 30;3(8):e1700521. doi: 10.1126/sciadv.1700521. eCollection 2017 Aug.


Natural and Semisynthetic Tigliane Diterpenoids with New Carbon Skeletons from Euphorbia dracunculoides as a Wnt Signaling Pathway Inhibitor.

Wang L, Yang J, Kong LM, Deng J, Xiong Z, Huang J, Luo J, Yan Y, Hu Y, Li XN, Li Y, Zhao Y, Huang SX.

Org Lett. 2017 Jul 21;19(14):3911-3914. doi: 10.1021/acs.orglett.7b01813. Epub 2017 Jul 13.


α-Pyrone Derivatives from a Streptomyces Strain Resensitize Tamoxifen Resistance in Breast Cancer Cells.

Yang RM, Zhang XL, Wang L, Huang JP, Yang J, Yan YJ, Luo JY, Wang XT, Huang SX.

Nat Prod Bioprospect. 2017 Aug;7(4):329-334. doi: 10.1007/s13659-017-0136-8. Epub 2017 Jun 20.


Effect of Hydraulic Retention Time on Anaerobic Digestion of Wheat Straw in the Semicontinuous Continuous Stirred-Tank Reactors.

Shi XS, Dong JJ, Yu JH, Yin H, Hu SM, Huang SX, Yuan XZ.

Biomed Res Int. 2017;2017:2457805. doi: 10.1155/2017/2457805. Epub 2017 May 14.


Up-regulated microRNA-299 corrected with poor prognosis of glioblastoma multiforme patients by targeting ELL2.

Huang Q, Zhang XW, Ma YS, Lu GX, Xie RT, Yang HQ, Lv ZW, Zhong XM, Liu T, Huang SX, Fu D, Xie C.

Jpn J Clin Oncol. 2017 Jul 1;47(7):590-596. doi: 10.1093/jjco/hyw188.


Prospective isolation of NKX2-1-expressing human lung progenitors derived from pluripotent stem cells.

Hawkins F, Kramer P, Jacob A, Driver I, Thomas DC, McCauley KB, Skvir N, Crane AM, Kurmann AA, Hollenberg AN, Nguyen S, Wong BG, Khalil AS, Huang SX, Guttentag S, Rock JR, Shannon JM, Davis BR, Kotton DN.

J Clin Invest. 2017 Jun 1;127(6):2277-2294. doi: 10.1172/JCI89950. Epub 2017 May 2.


A three-dimensional model of human lung development and disease from pluripotent stem cells.

Chen YW, Huang SX, de Carvalho ALRT, Ho SH, Islam MN, Volpi S, Notarangelo LD, Ciancanelli M, Casanova JL, Bhattacharya J, Liang AF, Palermo LM, Porotto M, Moscona A, Snoeck HW.

Nat Cell Biol. 2017 May;19(5):542-549. doi: 10.1038/ncb3510. Epub 2017 Apr 24.


Upregulation of miR-181a suppresses the formation of glioblastoma stem cells by targeting the Notch2 oncogene and correlates with good prognosis in patients with glioblastoma multiforme.

Huang SX, Zhao ZY, Weng GH, He XY, Wu CJ, Fu CY, Sui ZY, Ma YS, Liu T.

Biochem Biophys Res Commun. 2017 May 13;486(4):1129-1136. doi: 10.1016/j.bbrc.2017.04.008. Epub 2017 Apr 4.


Comprehensive assessments of long-term sleep habits in epidemiological study: Validity and reliability of sleep factors questionnaire (SFQ) among Chinese women.

Yang WS, Fu WX, Wang X, Deng Q, Wang L, Wang LY, Zhao H, Fan WY, Huang SX.

J Psychosom Res. 2017 Apr;95:12-18. doi: 10.1016/j.jpsychores.2017.02.005. Epub 2017 Feb 10.


[The relationship between oxygen saturation and related respiratory events in patients with obstructive sleep apnea-hypopnea syndrome].

Wang TT, Huang SX, Zhang XM, Zhang XW, Luo YX.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017 Feb 5;31(3):170-173. doi: 10.13201/j.issn.1001-1781.2017.03.002. Chinese.


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