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Decitabine Augments Chemotherapy-Induced PD-L1 Upregulation for PD-L1 Blockade in Colorectal Cancer.

Huang KC, Chiang SF, Chen WT, Chen TW, Hu CH, Yang PC, Ke TW, Chao KSC.

Cancers (Basel). 2020 Feb 17;12(2). pii: E462. doi: 10.3390/cancers12020462.


Biosurfactant-Mediated Membrane Depolarization Maintains Viability during Oxygen Depletion in Bacillus subtilis.

Arjes HA, Vo L, Dunn CM, Willis L, DeRosa CA, Fraser CL, Kearns DB, Huang KC.

Curr Biol. 2020 Feb 11. pii: S0960-9822(20)30117-2. doi: 10.1016/j.cub.2020.01.073. [Epub ahead of print]


Small Molecule Inhibition of CPS1 Activity through an Allosteric Pocket.

Yao S, Nguyen TV, Rolfe A, Agrawal AA, Ke J, Peng S, Colombo F, Yu S, Bouchard P, Wu J, Huang KC, Bao X, Omoto K, Selvaraj A, Yu L, Ioannidis S, Vaillancourt FH, Zhu P, Larsen NA, Bolduc DM.

Cell Chem Biol. 2020 Jan 28. pii: S2451-9456(20)30034-9. doi: 10.1016/j.chembiol.2020.01.009. [Epub ahead of print]


Prescription patterns of diabetes medications influencing clinical outcomes of heart failure patients with reduced ejection fraction.

Chang HY, Su YW, Feng AN, Fong MC, Huang KC, Chong E, Chen KC, Yin WH.

ESC Heart Fail. 2020 Jan 29. doi: 10.1002/ehf2.12617. [Epub ahead of print]


Bacterial interspecies interactions modulate pH-mediated antibiotic tolerance.

Aranda-Díaz A, Obadia B, Dodge R, Thomsen T, Hallberg ZF, Güvener ZT, Ludington WB, Huang KC.

Elife. 2020 Jan 29;9. pii: e51493. doi: 10.7554/eLife.51493.


Bellymount enables longitudinal, intravital imaging of abdominal organs and the gut microbiota in adult Drosophila.

Koyama LAJ, Aranda-Díaz A, Su YH, Balachandra S, Martin JL, Ludington WB, Huang KC, O'Brien LE.

PLoS Biol. 2020 Jan 27;18(1):e3000567. doi: 10.1371/journal.pbio.3000567. eCollection 2020 Jan.


Klebsiella michiganensis transmission enhances resistance to Enterobacteriaceae gut invasion by nutrition competition.

Oliveira RA, Ng KM, Correia MB, Cabral V, Shi H, Sonnenburg JL, Huang KC, Xavier KB.

Nat Microbiol. 2020 Jan 20. doi: 10.1038/s41564-019-0658-4. [Epub ahead of print]


Effect of mean HbA1c on the association of HbA1c variability and all-cause mortality in patients with type 2 diabetes.

Tseng JY, Chen HH, Huang KC, Hsu SP, Chen CC.

Diabetes Obes Metab. 2020 Jan 5. doi: 10.1111/dom.13951. [Epub ahead of print]


Quantitative imaging of intraerythrocytic hemozoin by transient absorption microscopy.

Chen AJ, Huang KC, Bopp S, Summers R, Dong P, Huang Y, Zong C, Wirth D, Cheng JX.

J Biomed Opt. 2019 Dec;25(1):1-11. doi: 10.1117/1.JBO.25.1.014507.


Dietary Antioxidant Trans-Cinnamaldehyde Reduced Visfatin-Induced Breast Cancer Progression: In Vivo and In Vitro Study.

Chiang YF, Chen HY, Huang KC, Lin PH, Hsia SM.

Antioxidants (Basel). 2019 Dec 6;8(12). pii: E625. doi: 10.3390/antiox8120625.


Machine learning can accurately predict pre-admission baseline hemoglobin and creatinine in intensive care patients.

Dauvin A, Donado C, Bachtiger P, Huang KC, Sauer CM, Ramazzotti D, Bonvini M, Celi LA, Douglas MJ.

NPJ Digit Med. 2019 Nov 29;2:116. doi: 10.1038/s41746-019-0192-z. eCollection 2019.


Treatment evolution and improved survival in multiple myeloma in Taiwan.

Tang CH, Hou HA, Huang KC, Qiu H, Liu Y.

Ann Hematol. 2020 Feb;99(2):321-330. doi: 10.1007/s00277-019-03858-w. Epub 2019 Dec 5.


A DNA Aptamer Targeting Galectin-1 as a Novel Immunotherapeutic Strategy for Lung Cancer.

Tsai YT, Liang CH, Yu JH, Huang KC, Tung CH, Wu JE, Wu YY, Chang CH, Hong TM, Chen YL.

Mol Ther Nucleic Acids. 2019 Dec 6;18:991-998. doi: 10.1016/j.omtn.2019.10.029. Epub 2019 Nov 2.


Simple and accurate visual detection of single nucleotide polymorphism based on colloidal gold nucleic acid strip biosensor and primer-specific PCR.

Wang HB, Ma LH, Zhang T, Huang KC, Zhao YD, Liu TC.

Anal Chim Acta. 2020 Jan 6;1093:106-114. doi: 10.1016/j.aca.2019.09.048. Epub 2019 Sep 20.


Recovery of the Gut Microbiota after Antibiotics Depends on Host Diet, Community Context, and Environmental Reservoirs.

Ng KM, Aranda-Díaz A, Tropini C, Frankel MR, Van Treuren W, O'Laughlin CT, Merrill BD, Yu FB, Pruss KM, Oliveira RA, Higginbottom SK, Neff NF, Fischbach MA, Xavier KB, Sonnenburg JL, Huang KC.

Cell Host Microbe. 2019 Nov 13;26(5):650-665.e4. doi: 10.1016/j.chom.2019.10.011.


Transplantation with GXHPC1 for Liver Cirrhosis: Phase 1 Trial.

Huang KC, Chuang MH, Lin ZS, Lin YC, Chen CH, Chang CL, Huang PC, Syu WS, Chiou TW, Hong ZH, Tsai YC, Harn HJ, Lin PC, Lin SZ.

Cell Transplant. 2019 Dec;28(1_suppl):100S-111S. doi: 10.1177/0963689719884885. Epub 2019 Nov 14.


Melatonin activates cell death programs for the suppression of uterine leiomyoma cell proliferation.

Lin PH, Tung YT, Chen HY, Chiang YF, Hong HC, Huang KC, Hsu SP, Huang TC, Hsia SM.

J Pineal Res. 2020 Jan;68(1):e12620. doi: 10.1111/jpi.12620. Epub 2019 Nov 28.


Decoupling of Rates of Protein Synthesis from Cell Expansion Leads to Supergrowth.

Knapp BD, Odermatt P, Rojas ER, Cheng W, He X, Huang KC, Chang F.

Cell Syst. 2019 Nov 27;9(5):434-445.e6. doi: 10.1016/j.cels.2019.10.001. Epub 2019 Nov 6.


A near-infrared light-controlled smart nanocarrier with reversible polypeptide-engineered valve for targeted fluorescence-photoacoustic bimodal imaging-guided chemo-photothermal therapy.

Li C, Yang XQ, An J, Cheng K, Hou XL, Zhang XS, Song XL, Huang KC, Chen W, Liu B, Zhao YD, Liu TC.

Theranostics. 2019 Oct 14;9(25):7666-7679. doi: 10.7150/thno.37047. eCollection 2019.


Performance and short-term outcomes of three different transcatheter aortic valve replacement devices in patients with aortic stenosis: A single-center experience.

Tzeng YH, Lee YT, Tsao TP, Lee KC, Huang KC, Hsiung MC, Wei J, Yin WH.

J Chin Med Assoc. 2019 Nov;82(11):827-834. doi: 10.1097/JCMA.0000000000000187.


Morphological and Molecular Defects in Human Three-Dimensional Retinal Organoid Model of X-Linked Juvenile Retinoschisis.

Huang KC, Wang ML, Chen SJ, Kuo JC, Wang WJ, Nhi Nguyen PN, Wahlin KJ, Lu JF, Tran AA, Shi M, Chien Y, Yarmishyn AA, Tsai PH, Yang TC, Jane WN, Chang CC, Peng CH, Schlaeger TM, Chiou SH.

Stem Cell Reports. 2019 Nov 12;13(5):906-923. doi: 10.1016/j.stemcr.2019.09.010. Epub 2019 Oct 24.


Hypoglycaemic episodes increase the risk of ventricular arrhythmia and sudden cardiac arrest in patients with type 2 diabetes-A nationwide cohort study.

Hsieh YC, Liao YC, Li CH, Lin JC, Weng CJ, Lin CC, Lo CP, Huang KC, Huang JL, Lin CH, Wang JS, Wu TJ, Sheu WH.

Diabetes Metab Res Rev. 2020 Feb;36(2):e3226. doi: 10.1002/dmrr.3226. Epub 2019 Oct 31.


Hepatic disease and the risk of mortality of Vibrio vulnificus necrotizing skin and soft tissue infections: A systematic review and meta-analysis.

Chuang PY, Yang TY, Huang TW, Tsai YH, Huang KC, Weng HH.

PLoS One. 2019 Oct 25;14(10):e0223513. doi: 10.1371/journal.pone.0223513. eCollection 2019.


Mechanically resolved imaging of bacteria using expansion microscopy.

Lim Y, Shiver AL, Khariton M, Lane KM, Ng KM, Bray SR, Qin J, Huang KC, Wang B.

PLoS Biol. 2019 Oct 17;17(10):e3000268. doi: 10.1371/journal.pbio.3000268. eCollection 2019 Oct.


Association between metabolic syndrome and limb muscle quantity and quality in older adults: a pilot ultrasound study.

Chang KV, Yang KC, Wu WT, Huang KC, Han DS.

Diabetes Metab Syndr Obes. 2019 Sep 11;12:1821-1830. doi: 10.2147/DMSO.S219649. eCollection 2019.


The effects of different fatigue levels on brain-behavior relationships in driving.

Huang KC, Chuang CH, Wang YK, Hsieh CY, King JT, Lin CT.

Brain Behav. 2019 Dec;9(12):e01379. doi: 10.1002/brb3.1379. Epub 2019 Sep 30.


Recovery of left ventricular dysfunction after sacubitril/valsartan: predictors and management.

Chang HY, Chen KC, Fong MC, Feng AN, Fu HN, Huang KC, Chong E, Yin WH.

J Cardiol. 2019 Sep 26. pii: S0914-5087(19)30264-3. doi: 10.1016/j.jjcc.2019.08.005. [Epub ahead of print]


Segmental body composition transitions in stroke patients: Trunks are different from extremities and strokes are as important as hemiparesis.

Chang KV, Wu WT, Huang KC, Han DS.

Clin Nutr. 2019 Aug 31. pii: S0261-5614(19)33036-5. doi: 10.1016/j.clnu.2019.08.024. [Epub ahead of print]


Cardiac manifestations and prognostic implications of hereditary transthyretin amyloidosis associated with transthyretin Ala97Ser.

Lai HJ, Huang KC, Liang YC, Chien KL, Lee MJ, Hsieh ST, Chao CC, Yang CC.

J Formos Med Assoc. 2019 Sep 11. pii: S0929-6646(19)30489-9. doi: 10.1016/j.jfma.2019.08.027. [Epub ahead of print]


Dovitinib Triggers Apoptosis and Autophagic Cell Death by Targeting SHP-1/p-STAT3 Signaling in Human Breast Cancers.

Chiu YH, Lee YY, Huang KC, Liu CC, Lin CS.

J Oncol. 2019 Aug 14;2019:2024648. doi: 10.1155/2019/2024648. eCollection 2019.


Advanced Age and Chronic Kidney Disease Modify the Association Between Metabolic Syndrome and Frailty Among Community-Dwelling Elderly.

Chao CT, Lee YH, Li CM, Han DS, Huang JW, Huang KC.

Rejuvenation Res. 2019 Oct 1. doi: 10.1089/rej.2019.2202. [Epub ahead of print]


Isoliquiritigenin Suppresses E2-Induced Uterine Leiomyoma Growth through the Modulation of Cell Death Program and the Repression of ECM Accumulation.

Lin PH, Kung HL, Chen HY, Huang KC, Hsia SM.

Cancers (Basel). 2019 Aug 7;11(8). pii: E1131. doi: 10.3390/cancers11081131.


Doses of hepatitis B revaccination needed for the seronegative youths to be seropositive to antibody against hepatitis B surface antigen.

Jan CF, Liu TH, Ho CH, Chien YC, Chang CJ, Guo FR, Huang KC.

Fam Pract. 2020 Feb 19;37(1):30-35. doi: 10.1093/fampra/cmz039.


Quantification of Stent Creep by Three-Dimensional Transesophageal Echocardiography in Patients Undergoing Transcatheter Aortic Valve-in-Valve Implantation for Failed Bioprostheses.

Huang KC, Yin WH, Lee YT, Tsao TP, Lee KC, Hsiung MC, Wei J.

Acta Cardiol Sin. 2019 Jul;35(4):380-386. doi: 10.6515/ACS.201907_35(4).20181126A.


Electronic Preresonance Stimulated Raman Scattering Imaging of Red-Shifted Proteorhodopsins: Toward Quantitation of the Membrane Potential.

Lee HJ, Huang KC, Mei G, Zong C, Mamaeva N, DeGrip WJ, Rothschild KJ, Cheng JX.

J Phys Chem Lett. 2019 Aug 1;10(15):4374-4381. doi: 10.1021/acs.jpclett.9b01337. Epub 2019 Jul 22.


Comparison of implant failure rates of different plates for midshaft clavicular fractures based on fracture classifications.

Chiu YC, Huang KC, Shih CM, Lee KT, Chen KH, Hsu CE.

J Orthop Surg Res. 2019 Jul 16;14(1):220. doi: 10.1186/s13018-019-1259-x.


Chromosome Organization: Making Room in a Crowd.

Shi H, Huang KC.

Curr Biol. 2019 Jul 8;29(13):R630-R632. doi: 10.1016/j.cub.2019.06.002.


Increasing risk of diabetes mellitus in postmenopausal women with newly diagnosed primary breast cancer.

Wang CY, Shih SR, Huang KC.

J Diabetes Investig. 2019 Jul 4. doi: 10.1111/jdi.13112. [Epub ahead of print]


Zoledronate induces cell cycle arrest and differentiation by upregulating p21 in mouse MC3T3-E1 preosteoblasts.

Huang KC, Huang TW, Chuang PY, Yang TY, Chang SF.

Int J Med Sci. 2019 May 10;16(5):751-756. doi: 10.7150/ijms.32612. eCollection 2019.


Hyperglycemia inhibits osteoblastogenesis of rat bone marrow stromal cells via activation of the Notch2 signaling pathway.

Huang KC, Chuang PY, Yang TY, Huang TW, Chang SF.

Int J Med Sci. 2019 May 10;16(5):696-703. doi: 10.7150/ijms.32707. eCollection 2019.


Deferred treatment with a fixed-dose combination of sofosbuvir-velpatasvir for chronic hepatitis C virus genotype 1, 2, 4 and 6 infection.

Asselah T, Shafran SD, Bourgeois S, Lai CL, Mathurin P, Willems B, Nguyen MH, Davis MN, Huang KC, Svarovskaia E, Osinusi A, McNally J, Brainard DM, Shaikh OS, Tran TT.

J Viral Hepat. 2019 Oct;26(10):1229-1232. doi: 10.1111/jvh.13159. Epub 2019 Aug 4.


Chronic Viral Hepatitis Signifies the Association of Premixed Insulin Analogues with Liver Cancer Risks: A Nationwide Population-Based Study.

Chiang CH, Kuo CS, Lin WW, Su JH, Chen JD, Huang KC.

Int J Environ Res Public Health. 2019 Jun 13;16(12). pii: E2097. doi: 10.3390/ijerph16122097.


Fabrication of Hydrophilic Surface on Rigid Gas Permeable Contact Lenses to Enhance the Wettability Using Ultraviolet Laser System.

Tsai HY, Hsieh YC, Lin YH, Chang HC, Tang YH, Huang KC.

Micromachines (Basel). 2019 Jun 13;10(6). pii: E394. doi: 10.3390/mi10060394.


Overexpression of Kynurenine 3-Monooxygenase Correlates with Cancer Malignancy and Predicts Poor Prognosis in Canine Mammary Gland Tumors.

Chiu YH, Lei HJ, Huang KC, Chiang YL, Lin CS.

J Oncol. 2019 May 2;2019:6201764. doi: 10.1155/2019/6201764. eCollection 2019.


Environmental effects on the bioaccumulation of PAHs in marine zooplankton in Gaoping coastal waters, Taiwan: Concentration, distribution, profile, and sources.

Hsieh HY, Huang KC, Cheng JO, Lo WT, Meng PJ, Ko FC.

Mar Pollut Bull. 2019 Jul;144:68-78. doi: 10.1016/j.marpolbul.2019.04.048. Epub 2019 May 10.


Computed Tomography-Determined Muscle Quality Rather Than Muscle Quantity Is a Better Determinant of Prolonged Hospital Length of Stay in Patients Undergoing Transcatheter Aortic Valve Implantation.

Tzeng YH, Wei J, Tsao TP, Lee YT, Lee KC, Liou HR, Sung HJ, Huang KC, Hsiung MC, Yin WH.

Acad Radiol. 2020 Mar;27(3):381-388. doi: 10.1016/j.acra.2019.05.007. Epub 2019 May 31.


Metabolic Characteristics of a Novel Ultrasound Quantitative Diagnostic Index for Nonalcoholic Fatty Liver Disease.

Liao YY, Yeh CK, Huang KC, Tsui PH, Yang KC.

Sci Rep. 2019 May 28;9(1):7922. doi: 10.1038/s41598-019-44453-3.


tRNA Methylation Is a Global Determinant of Bacterial Multi-drug Resistance.

Masuda I, Matsubara R, Christian T, Rojas ER, Yadavalli SS, Zhang L, Goulian M, Foster LJ, Huang KC, Hou YM.

Cell Syst. 2019 May 22;8(5):475. doi: 10.1016/j.cels.2019.05.002. No abstract available.


Label-free quantitation of glycated hemoglobin in single red blood cells by transient absorption microscopy and phasor analysis.

Dong PT, Lin H, Huang KC, Cheng JX.

Sci Adv. 2019 May 10;5(5):eaav0561. doi: 10.1126/sciadv.aav0561. eCollection 2019 May.


Results of Conversion from Failed Austin-Moore Hemiarthroplasty to Cementless Total Hip Arthroplasty in Octogenarian Patients with Advanced Acetabular Erosion: A Minimum of 5 Years of Follow-Up.

Huang TW, Chang CH, Chang FC, Chen CC, Huang KC, Lee MS, Shih HN.

Biomed Res Int. 2019 Apr 2;2019:7814602. doi: 10.1155/2019/7814602. eCollection 2019.

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