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Items: 1 to 50 of 89


Cancer-predicting transcriptomic and epigenetic signatures revealed for ulcerative colitis in patient-derived epithelial organoids.

Sarvestani SK, Signs SA, Lefebvre V, Mack S, Ni Y, Morton A, Chan ER, Li X, Fox P, Ting A, Kalady MF, Cruise M, Ashburn J, Stiene J, Lai W, Liska D, Xiang S, Huang EH.

Oncotarget. 2018 Jun 19;9(47):28717-28730. doi: 10.18632/oncotarget.25617. eCollection 2018 Jun 19.


Stromal miR-20a controls paracrine CXCL8 secretion in colitis and colon cancer.

Signs SA, Fisher RC, Tran U, Chakrabarti S, Sarvestani SK, Xiang S, Liska D, Roche V, Lai W, Gittleman HR, Wessely O, Huang EH.

Oncotarget. 2018 Feb 14;9(16):13048-13059. doi: 10.18632/oncotarget.24495. eCollection 2018 Feb 27.


Local drug delivery in the urinary tract: current challenges and opportunities.

Mittal R, Pan DR, Parrish JM, Huang EH, Yang Y, Patel AP, Malhotra AK, Mittal J, Chhibber S, Harjai K.

J Drug Target. 2018 Sep;26(8):658-669. doi: 10.1080/1061186X.2017.1419356. Epub 2018 Jan 17.


A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer.

Yochum ZA, Cades J, Mazzacurati L, Neumann NM, Khetarpal SK, Chatterjee S, Wang H, Attar MA, Huang EH, Chatley SN, Nugent K, Somasundaram A, Engh JA, Ewald AJ, Cho YJ, Rudin CM, Tran PT, Burns TF.

Mol Cancer Res. 2017 Dec;15(12):1764-1776. doi: 10.1158/1541-7786.MCR-17-0298. Epub 2017 Aug 29.


Reactivation of the p90RSK-CDC25C Pathway Leads to Bypass of the Ganetespib-Induced G2-M Arrest and Mediates Acquired Resistance to Ganetespib in KRAS-Mutant NSCLC.

Chatterjee S, Huang EH, Christie I, Burns TF.

Mol Cancer Ther. 2017 Aug;16(8):1658-1668. doi: 10.1158/1535-7163.MCT-17-0114. Epub 2017 May 31.


Acquired Resistance to the Hsp90 Inhibitor, Ganetespib, in KRAS-Mutant NSCLC Is Mediated via Reactivation of the ERK-p90RSK-mTOR Signaling Network.

Chatterjee S, Huang EH, Christie I, Kurland BF, Burns TF.

Mol Cancer Ther. 2017 May;16(5):793-804. doi: 10.1158/1535-7163.MCT-16-0677. Epub 2017 Feb 6.


Inhibition of PI3K/Akt/mTOR signaling in PI3KR2-overexpressing colon cancer stem cells reduces tumor growth due to apoptosis.

Chen S, Fisher RC, Signs S, Molina LA, Shenoy AK, Lopez MC, Baker HV, Koomen JM, Chen Y, Gittleman H, Barnholtz-Sloan J, Berg A, Appelman HD, Huang EH.

Oncotarget. 2016 Jun 8;8(31):50476-50488. doi: 10.18632/oncotarget.9919. eCollection 2017 Aug 1.


Induction of antigen-specific TH 9 immunity accompanied by mast cell activation blocks tumor cell engraftment.

Abdul-Wahid A, Cydzik M, Prodeus A, Alwash M, Stanojcic M, Thompson M, Huang EH, Shively JE, Gray-Owen SD, Gariépy J.

Int J Cancer. 2016 Aug 15;139(4):841-53. doi: 10.1002/ijc.30121. Epub 2016 Apr 15.


CDX2: Linking Cell and Patient Fates in Colon Cancer.

Fearon ER, Huang EH.

Cell Stem Cell. 2016 Feb 4;18(2):168-9. doi: 10.1016/j.stem.2016.01.011.


A Rare Cause of Hepatic Portal Venous Gas with Gastric Emphysema.

Liao CY, Hsieh AT, Huang EH, Lee CC.

Intern Med. 2015;54(22):2947. doi: 10.2169/internalmedicine.54.5267. Epub 2015 Nov 15. No abstract available.


Bizarre Radiographic Finding in a Female Soldier.

Liao CY, Huang EH, Lin JH.

Am J Med Sci. 2015 Nov;350(5):e5. doi: 10.1097/MAJ.0000000000000493. No abstract available.


Accuracy of A Handheld Accelerometer-Based Navigation System for Femoral and Tibial Resection in Total Knee Arthroplasty.

Huang EH, Copp SN, Bugbee WD.

J Arthroplasty. 2015 Nov;30(11):1906-10. doi: 10.1016/j.arth.2015.05.055. Epub 2015 Jun 6.


A diagnostic dilemma: acute abdomen presenting as segmental arterial mediolysis masked by a ruptured hepatocellular carcinoma.

Liao CY, Kuo WH, Huang EH, Hsieh AT, Le CC, Tsai CC, Hsueh CW.

Gastroenterol Rep (Oxf). 2017 Aug;5(3):244-246. doi: 10.1093/gastro/gov030. Epub 2015 Jul 10.


Drug-eluting microarrays to identify effective chemotherapeutic combinations targeting patient-derived cancer stem cells.

Carstens MR, Fisher RC, Acharya AP, Butterworth EA, Scott E, Huang EH, Keselowsky BG.

Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8732-7. doi: 10.1073/pnas.1505374112. Epub 2015 Jun 29.


Targeting the PD-1/PD-L1 Immune Evasion Axis With DNA Aptamers as a Novel Therapeutic Strategy for the Treatment of Disseminated Cancers.

Prodeus A, Abdul-Wahid A, Fischer NW, Huang EH, Cydzik M, Gariépy J.

Mol Ther Nucleic Acids. 2015 Apr 28;4:e237. doi: 10.1038/mtna.2015.11.


Achalasia and pneumonia.

Liao CY, Huang EH, Huang SF.

QJM. 2015 Sep;108(9):751-2. doi: 10.1093/qjmed/hcv074. Epub 2015 Apr 3. No abstract available.


Enterococcus casseliflavus endophthalmitis due to metallic intraocular foreign body.

Low JR, Teoh CS, Chien JM, Huang EH.

Eye (Lond). 2015 Jun;29(6):840-1. doi: 10.1038/eye.2014.332. Epub 2015 Feb 6. No abstract available.


The colon cancer stem cell microenvironment holds keys to future cancer therapy.

Chen S, Huang EH.

J Gastrointest Surg. 2014 May;18(5):1040-8. doi: 10.1007/s11605-014-2497-1. Epub 2014 Mar 19. Review.


The carcinoembryonic antigen IgV-like N domain plays a critical role in the implantation of metastatic tumor cells.

Abdul-Wahid A, Huang EH, Cydzik M, Bolewska-Pedyczak E, Gariépy J.

Mol Oncol. 2014 Mar;8(2):337-50. doi: 10.1016/j.molonc.2013.12.002. Epub 2013 Dec 17.


Primary breast lymphoma.

Huang EH, Lin SF, Yin HL, Hsu JS.

Kaohsiung J Med Sci. 2013 Aug;29(8):464-5. doi: 10.1016/j.kjms.2012.12.008. Epub 2013 Feb 15. No abstract available.


Blocking the attachment of cancer cells in vivo with DNA aptamers displaying anti-adhesive properties against the carcinoembryonic antigen.

Orava EW, Abdul-Wahid A, Huang EH, Mallick AI, Gariépy J.

Mol Oncol. 2013 Aug;7(4):799-811. doi: 10.1016/j.molonc.2013.03.005. Epub 2013 Apr 11.


Effect of various hallux valgus reconstruction on sesamoid location: a radiographic study.

Huang EH, Charlton TP, Ajayi S, Thordarson DB.

Foot Ankle Int. 2013 Jan;34(1):99-103. doi: 10.1177/1071100712464356.


The Pseudomonas aeruginosa exotoxin A translocation domain facilitates the routing of CPP-protein cargos to the cytosol of eukaryotic cells.

Mohammed AF, Abdul-Wahid A, Huang EH, Bolewska-Pedyczak E, Cydzik M, Broad AE, Gariépy J.

J Control Release. 2012 Nov 28;164(1):58-64. doi: 10.1016/j.jconrel.2012.10.006. Epub 2012 Oct 14.


Transanal excision with radiation therapy for rectal adenocarcinoma.

Tennyson N, Mendenhall WM, Morris CG, Huang EH, Zlotecki RA.

Clin Med Res. 2012 Nov;10(4):224-9. doi: 10.3121/cmr.2012.1072. Epub 2012 Sep 20.


ALDH as a marker for enriching tumorigenic human colonic stem cells.

Shenoy A, Butterworth E, Huang EH.

Methods Mol Biol. 2012;916:373-85. doi: 10.1007/978-1-61779-980-8_27.


Transition from colitis to cancer: high Wnt activity sustains the tumor-initiating potential of colon cancer stem cell precursors.

Shenoy AK, Fisher RC, Butterworth EA, Pi L, Chang LJ, Appelman HD, Chang M, Scott EW, Huang EH.

Cancer Res. 2012 Oct 1;72(19):5091-100. doi: 10.1158/0008-5472.CAN-12-1806. Epub 2012 Aug 17.


A case of post-vaccination optic neuritis: coincidence or causative?

Sudarshan S, Huang EH, Lim PL, Leo YS, Lim SA.

Eye (Lond). 2012 Nov;26(11):1498. doi: 10.1038/eye.2012.146. Epub 2012 Aug 10. No abstract available.


Impact of internal metallic ports in temporary tissue expanders on postmastectomy radiation dose distribution.

Chen SA, Ogunleye T, Dhabbaan A, Huang EH, Losken A, Gabram S, Davis L, Torres MA.

Int J Radiat Oncol Biol Phys. 2013 Mar 1;85(3):630-5. doi: 10.1016/j.ijrobp.2012.06.046. Epub 2012 Aug 8.


A focused immune response targeting the homotypic binding domain of the carcinoembryonic antigen blocks the establishment of tumor foci in vivo.

Abdul-Wahid A, Huang EH, Lu H, Flanagan J, Mallick AI, Gariépy J.

Int J Cancer. 2012 Dec 15;131(12):2839-51. doi: 10.1002/ijc.27582. Epub 2012 May 8.


Can we develop effective combination antiangiogenic therapy for patients with hepatocellular carcinoma?

Wenger JB, Santos N, Liu Y, Dallas J, Subbiah S, Hochwald S, Huang EH, Dang DT, Allegra CJ, Luesch H, Dang LH.

Oncol Rev. 2011 Sep;5(3):177-184.


Reproducibility of cornea measurements in anterior segment OCT images of normal eyes and eyes with bullous keratopathy analyzed with the Zhongshan Assessment Program.

Chan JB, Yuen LH, Huang EH, Htoon HM, He M, Aung T, Tan DT, Mehta JS.

Invest Ophthalmol Vis Sci. 2011 Nov 17;52(12):8884-90. doi: 10.1167/iovs.10-6411.



Hughes MR, Huang EH.

Semin Colon Rectal Surg. 2011 Jun 1;22(2):65-70.


Classification of ipsilateral breast tumor recurrences after breast conservation therapy can predict patient prognosis and facilitate treatment planning.

Yi M, Buchholz TA, Meric-Bernstam F, Bedrosian I, Hwang RF, Ross MI, Kuerer HM, Luo S, Gonzalez-Angulo AM, Buzdar AU, Symmans WF, Feig BW, Lucci A, Huang EH, Hunt KK.

Ann Surg. 2011 Mar;253(3):572-9. doi: 10.1097/SLA.0b013e318208fc2a.


Evaluation of a CXCR4 antagonist in a xenograft mouse model of inflammatory breast cancer.

Singh B, Cook KR, Martin C, Huang EH, Mosalpuria K, Krishnamurthy S, Cristofanilli M, Lucci A.

Clin Exp Metastasis. 2010 Apr;27(4):233-40. doi: 10.1007/s10585-010-9321-4. Epub 2010 Mar 13.


Atorvastatin induces apoptosis in vitro and slows growth of tumor xenografts but not polyp formation in MIN mice.

Huang EH, Johnson LA, Eaton K, Hynes MJ, Carpentino JE, Higgins PD.

Dig Dis Sci. 2010 Nov;55(11):3086-94. doi: 10.1007/s10620-010-1157-x. Epub 2010 Feb 26.


Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer.

Carpentino JE, Hynes MJ, Appelman HD, Zheng T, Steindler DA, Scott EW, Huang EH.

Cancer Res. 2009 Oct 15;69(20):8208-15. doi: 10.1158/0008-5472.CAN-09-1132. Epub 2009 Oct 6.


Retrobulbar optic neuritis after Hepatitis A vaccination in a HIV-infected patient.

Huang EH, Lim SA, Lim PL, Leo YS.

Eye (Lond). 2009 Dec;23(12):2267-71. doi: 10.1038/eye.2009.223. No abstract available.


A CXCR4 antagonist CTCE-9908 inhibits primary tumor growth and metastasis of breast cancer.

Huang EH, Singh B, Cristofanilli M, Gelovani J, Wei C, Vincent L, Cook KR, Lucci A.

J Surg Res. 2009 Aug;155(2):231-6. doi: 10.1016/j.jss.2008.06.044. Epub 2008 Aug 9. Erratum in: J Surg Res. 2010 Aug;162(2):169.


Review paper: Implications of the "cancer stem cell" hypothesis on murine models of colon cancer and colitis-associated cancer.

Hynes MJ, Huang KM, Huang EH.

Vet Pathol. 2009 Sep;46(5):819-35. doi: 10.1354/vp.08-VP-0172-H-REV. Epub 2009 May 9. Review.


Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis.

Huang EH, Hynes MJ, Zhang T, Ginestier C, Dontu G, Appelman H, Fields JZ, Wicha MS, Boman BM.

Cancer Res. 2009 Apr 15;69(8):3382-9. doi: 10.1158/0008-5472.CAN-08-4418. Epub 2009 Mar 31.


Colon cancer stem cells: implications for prevention and therapy.

Huang EH, Wicha MS.

Trends Mol Med. 2008 Nov;14(11):503-9. doi: 10.1016/j.molmed.2008.09.005. Epub 2008 Oct 17. Review.


RAGE and RAGE ligands in cancer.

Logsdon CD, Fuentes MK, Huang EH, Arumugam T.

Curr Mol Med. 2007 Dec;7(8):777-89. Review.


Health literacy and health outcomes in HIV seropositive persons.

Nokes KM, Coleman CL, Cashen M, Dole P, Sefcik E, Hamilton MJ, Kirksey KM, Huang EH, Apinya J, Holzemer W.

Res Nurs Health. 2007 Dec;30(6):620-7.


Long-term results of the M. D. Anderson randomized dose-escalation trial for prostate cancer.

Kuban DA, Tucker SL, Dong L, Starkschall G, Huang EH, Cheung MR, Lee AK, Pollack A.

Int J Radiat Oncol Biol Phys. 2008 Jan 1;70(1):67-74. Epub 2007 Aug 31.


A phase II study of preoperative capecitabine and radiation therapy in patients with rectal cancer.

Desai SP, El-Rayes BF, Ben-Josef E, Greenson JK, Knol JA, Huang EH, Griffith KA, Philip PA, McGinn CJ, Zalupski MM.

Am J Clin Oncol. 2007 Aug;30(4):340-5.


RAGE activation by S100P in colon cancer stimulates growth, migration, and cell signaling pathways.

Fuentes MK, Nigavekar SS, Arumugam T, Logsdon CD, Schmidt AM, Park JC, Huang EH.

Dis Colon Rectum. 2007 Aug;50(8):1230-40.


Phenotypic characterization of human colorectal cancer stem cells.

Dalerba P, Dylla SJ, Park IK, Liu R, Wang X, Cho RW, Hoey T, Gurney A, Huang EH, Simeone DM, Shelton AA, Parmiani G, Castelli C, Clarke MF.

Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10158-63. Epub 2007 Jun 4.


Postmastectomy radiation improves the outcome of patients with locally advanced breast cancer who achieve a pathologic complete response to neoadjuvant chemotherapy.

McGuire SE, Gonzalez-Angulo AM, Huang EH, Tucker SL, Kau SW, Yu TK, Strom EA, Oh JL, Woodward WA, Tereffe W, Hunt KK, Kuerer HM, Sahin AA, Hortobagyi GN, Buchholz TA.

Int J Radiat Oncol Biol Phys. 2007 Jul 15;68(4):1004-9. Epub 2007 Apr 6.


Comparison of outcomes for patients with unresectable, locally advanced non-small-cell lung cancer treated with induction chemotherapy followed by concurrent chemoradiation vs. concurrent chemoradiation alone.

Huang EH, Liao Z, Cox JD, Guerrero TM, Chang JY, Jeter M, Borghero Y, Wei X, Fossella F, Herbst RS, Blumenschein GR Jr, Moran C, Allen PK, Komaki R.

Int J Radiat Oncol Biol Phys. 2007 Jul 1;68(3):779-85. Epub 2007 Apr 6.


Cancer stem cells: a new paradigm for understanding tumor progression and therapeutic resistance.

Huang EH, Heidt DG, Li CW, Simeone DM.

Surgery. 2007 Apr;141(4):415-9. Review. No abstract available.


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