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Combinatorial targeting of MTHFD2 and PAICS in purine synthesis as a novel therapeutic strategy.

Cheung CHY, Hsu CL, Tsuei CY, Kuo TT, Huang CT, Hsu WM, Chung YH, Wu HY, Hsu CC, Huang HC, Juan HF.

Cell Death Dis. 2019 Oct 17;10(11):786. doi: 10.1038/s41419-019-2033-z.


Prognostic value of the mitogen response in the interferon-γ release assay in patients with culture-confirmed tuberculosis.

Huang CT, Lee MR, Ruan SY, Tsai YJ, Wang JY, Yu CJ.

Respir Med. 2019 Oct 7;158:49-54. doi: 10.1016/j.rmed.2019.10.004. [Epub ahead of print]


Quantitative Proteomics of Th-MYCN Transgenic Mice Reveals Aurora Kinase Inhibitor Altered Metabolic Pathways and Enhanced ACADM To Suppress Neuroblastoma Progression.

Hsieh CH, Cheung CHY, Liu YL, Hou CL, Hsu CL, Huang CT, Yang TS, Chen SF, Chen CN, Hsu WM, Huang HC, Juan HF.

J Proteome Res. 2019 Oct 11. doi: 10.1021/acs.jproteome.9b00245. [Epub ahead of print]


Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis.

Sohn PD, Huang CT, Yan R, Fan L, Tracy TE, Camargo CM, Montgomery KM, Arhar T, Mok SA, Freilich R, Baik J, He M, Gong S, Roberson ED, Karch CM, Gestwicki JE, Xu K, Kosik KS, Gan L.

Neuron. 2019 Sep 4. pii: S0896-6273(19)30692-0. doi: 10.1016/j.neuron.2019.08.008. [Epub ahead of print]


Differential roles of comorbidity burden and functional status in elderly and non-elderly patients with infections in general wards.

Chou HC, Huang CT, Sheng WH.

J Formos Med Assoc. 2019 Sep 11. pii: S0929-6646(19)30584-4. doi: 10.1016/j.jfma.2019.08.032. [Epub ahead of print]


Intraoral Air Abrasion: A Review of Devices, Materials, Evidence, and Clinical Applications in Restorative Dentistry.

Huang CT, Kim J, Arce C, Lawson NC.

Compend Contin Educ Dent. 2019 Sep;40(8):508-513; quiz 514.


Effect of aloin on viral neuraminidase and hemagglutinin-specific T cell immunity in acute influenza.

Huang CT, Hung CY, Hseih YC, Chang CS, Velu AB, He YC, Huang YL, Chen TA, Chen TC, Lin CY, Lin YC, Shih SR, Dutta A.

Phytomedicine. 2019 Apr 4;64:152904. doi: 10.1016/j.phymed.2019.152904. [Epub ahead of print]


The efficacy and safety of concentrated herbal extract granules, YH1, as an add-on medication in poorly controlled type 2 diabetes: A randomized, double-blind, placebo-controlled pilot trial.

Huang YH, Chen ST, Liu FH, Hsieh SH, Lin CH, Liou MJ, Wang CC, Huang CH, Liu GH, Lin JR, Yang LY, Hsu TY, Lee MC, Huang CT, Wu YH.

PLoS One. 2019 Aug 15;14(8):e0221199. doi: 10.1371/journal.pone.0221199. eCollection 2019.


Mitochondrial DNA Variants in Patients with Liver Injury Due to Anti-Tuberculosis Drugs.

Lee LN, Huang CT, Hsu CL, Chang HC, Jan IS, Liu JL, Sheu JC, Wang JT, Liu WL, Wu HS, Chang CN, Wang JY.

J Clin Med. 2019 Aug 13;8(8). pii: E1207. doi: 10.3390/jcm8081207.


Clinical Trajectories and Causes of Death in Septic Patients with a Low APACHE II Score.

Huang CT, Ruan SY, Tsai YJ, Ku SC, Yu CJ.

J Clin Med. 2019 Jul 20;8(7). pii: E1064. doi: 10.3390/jcm8071064.


Development of a Transgenic Flammulina velutipes Oral Vaccine for Hepatitis B.

Huang LH, Lin HY, Lyu YT, Gung CL, Huang CT.

Food Technol Biotechnol. 2019 Mar;57(1):105-112. doi: 10.17113/ftb.


Clinical features, microbiological epidemiology and recommendations for management of cellulitis in extremity lymphedema.

Rodriguez JR, Hsieh F, Huang CT, Tsai TJ, Chen C, Cheng MH.

J Surg Oncol. 2019 Jul 2. doi: 10.1002/jso.25525. [Epub ahead of print]


Effect of Surface Treatment and Cement on Fracture Load of Traditional Zirconia (3Y), Translucent Zirconia (5Y), and Lithium Disilicate Crowns.

Lawson NC, Jurado CA, Huang CT, Morris GP, Burgess JO, Liu PR, Kinderknecht KE, Lin CP, Givan DA.

J Prosthodont. 2019 Jul;28(6):659-665. doi: 10.1111/jopr.13088. Epub 2019 Jun 11.


Randomized Noninferiority Trial of Cefoperazone-Sulbactam versus Cefepime in the Treatment of Hospital-Acquired and Healthcare-Associated Pneumonia.

Liu JW, Chen YH, Lee WS, Lin JC, Huang CT, Lin HH, Liu YC, Chuang YC, Tang HJ, Chen YS, Ko WC, Lu MC, Wang FD.

Antimicrob Agents Chemother. 2019 Jul 25;63(8). pii: e00023-19. doi: 10.1128/AAC.00023-19. Print 2019 Aug.


Early blastocyst expansion in euploid and aneuploid human embryos: evidence for a non-invasive and quantitative marker for embryo selection.

Huang TT, Huang DH, Ahn HJ, Arnett C, Huang CT.

Reprod Biomed Online. 2019 Jul;39(1):27-39. doi: 10.1016/j.rbmo.2019.01.010. Epub 2019 Jan 23.


Perturbational Gene-Expression Signatures for Combinatorial Drug Discovery.

Huang CT, Hsieh CH, Chung YH, Oyang YJ, Huang HC, Juan HF.

iScience. 2019 May 31;15:291-306. doi: 10.1016/j.isci.2019.04.039. Epub 2019 May 4.


Resolution-enhanced light field displays by recombining subpixels across elemental images.

Qin Z, Chou PY, Wu JY, Huang CT, Huang YP.

Opt Lett. 2019 May 15;44(10):2438-2441. doi: 10.1364/OL.44.002438.


Reappraisal of Failures in Downstaging Treatment of Hepatocellular Carcinoma Prior to Liver Transplant-Preliminary Report on the Impact of Underestimations of Tumor Numbers and Tumor Sizes as Measured From Imaging Before Transplant.

Jeng KS, Huang CC, Lin CK, Lin CC, Huang CT, Chung CS, Weng MT, Chen KH.

Transplant Proc. 2019 Jun;51(5):1428-1434. doi: 10.1016/j.transproceed.2019.03.020. Epub 2019 May 9.


Transfemoral Approach for Intraoperative Angiography in the Prone or Three-quarter Prone Position : A Revisited Protocol for Intracranial Arteriovenous Malformation and Fistula Surgery.

Wang C, Hsu SK, Chang CJ, Chen MH, Huang CT, Huang JS, Su IC.

Clin Neuroradiol. 2019 Apr 29. doi: 10.1007/s00062-019-00783-3. [Epub ahead of print]


MiR-338-5p promotes metastasis of colorectal cancer by inhibition of phosphatidylinositol 3-kinase, catalytic subunit type 3-mediated autophagy pathway.

Chu CA, Lee CT, Lee JC, Wang YW, Huang CT, Lan SH, Lin PC, Lin BW, Tian YF, Liu HS, Chow NH.

EBioMedicine. 2019 May;43:270-281. doi: 10.1016/j.ebiom.2019.04.010. Epub 2019 Apr 12.


Investigation of the Viscoelastic Behavior Variation of Glass Mat Thermoplastics (GMT) in Compression Molding.

Huang CT, Chen LJ, Chien TY.

Polymers (Basel). 2019 Feb 14;11(2). pii: E335. doi: 10.3390/polym11020335.


Metformin use mitigates the adverse prognostic effect of diabetes mellitus in chronic obstructive pulmonary disease.

Ho TW, Huang CT, Tsai YJ, Lien AS, Lai F, Yu CJ.

Respir Res. 2019 Apr 5;20(1):69. doi: 10.1186/s12931-019-1035-9.


Therapeutic Targeting of Non-oncogene Dependencies in High-risk Neuroblastoma.

Huang CT, Hsieh CH, Lee WC, Liu YL, Yang TS, Hsu WM, Oyang YJ, Huang HC, Juan HF.

Clin Cancer Res. 2019 Jul 1;25(13):4063-4078. doi: 10.1158/1078-0432.CCR-18-4117. Epub 2019 Apr 5.


Advances in exosomes technology.

Chen BY, Sung CW, Chen C, Cheng CM, Lin DP, Huang CT, Hsu MY.

Clin Chim Acta. 2019 Jun;493:14-19. doi: 10.1016/j.cca.2019.02.021. Epub 2019 Feb 21. Review.


Impact of a home health care program for disabled patients in Taiwan: A nationwide population-based cohort study.

Lee YH, Lu CW, Huang CT, Chang HH, Yang KC, Kuo CS, Chang YK, Hsu CC, Huang KC.

Medicine (Baltimore). 2019 Feb;98(7):e14502. doi: 10.1097/MD.0000000000014502.


Appropriate Treatment for Bloodstream Infections Due to Carbapenem-Resistant Klebsiella pneumoniae and Escherichia coli: A Nationwide Multicenter Study in Taiwan.

Lin YT, Su CF, Chuang C, Lin JC, Lu PL, Huang CT, Wang JT, Chuang YC, Siu LK, Fung CP.

Open Forum Infect Dis. 2018 Dec 17;6(2):ofy336. doi: 10.1093/ofid/ofy336. eCollection 2019 Feb.


Presynaptic SNAP-25 regulates retinal waves and retinogeniculate projection via phosphorylation.

Hsiao YT, Shu WC, Chen PC, Yang HJ, Chen HY, Hsu SP, Huang YT, Yang CC, Chen YJ, Yu NY, Liou SY, Chiang N, Huang CT, Cheng TL, Cheung LY, Lin YC, Lu JC, Wang CT.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3262-3267. doi: 10.1073/pnas.1812169116. Epub 2019 Feb 6.


Hybrid light field head-mounted display using time-multiplexed liquid crystal lens array for resolution enhancement.

Chou PY, Wu JY, Huang SH, Wang CP, Qin Z, Huang CT, Hsieh PY, Lee HH, Lin TH, Huang YP.

Opt Express. 2019 Jan 21;27(2):1164-1177. doi: 10.1364/OE.27.001164.


Zika Virus: Origins, Pathological Action, and Treatment Strategies.

Gorshkov K, Shiryaev SA, Fertel S, Lin YW, Huang CT, Pinto A, Farhy C, Strongin AY, Zheng W, Terskikh AV.

Front Microbiol. 2019 Jan 7;9:3252. doi: 10.3389/fmicb.2018.03252. eCollection 2018. Review.


Varlitinib Downregulates HER/ERK Signaling and Induces Apoptosis in Triple Negative Breast Cancer Cells.

Liu CY, Chu PY, Huang CT, Chen JL, Yang HP, Wang WL, Lau KY, Lee CH, Lan TY, Huang TT, Lin PH, Dai MS, Tseng LM.

Cancers (Basel). 2019 Jan 17;11(1). pii: E105. doi: 10.3390/cancers11010105.


Targeting SET to restore PP2A activity disrupts an oncogenic CIP2A-feedforward loop and impairs triple negative breast cancer progression.

Liu CY, Huang TT, Chen YT, Chen JL, Chu PY, Huang CT, Wang WL, Lau KY, Dai MS, Shiau CW, Tseng LM.

EBioMedicine. 2019 Feb;40:263-275. doi: 10.1016/j.ebiom.2018.12.032. Epub 2019 Jan 14.


Enhancing the efficiency of the Pichia pastoris AOX1 promoter via the synthetic positive feedback circuit of transcription factor Mxr1.

Chang CH, Hsiung HA, Hong KL, Huang CT.

BMC Biotechnol. 2018 Dec 27;18(1):81. doi: 10.1186/s12896-018-0492-4.


Induction of liver-specific intrahepatic myeloid cells aggregation expands CD8 T cell and inhibits growth of murine hepatoma.

Lin YC, Hsu CY, Huang SK, Fan YH, Huang CH, Yang CK, Su WT, Chang PC, Dutta A, Liu YJ, Huang CT, Chen TC, Lin CY.

Oncoimmunology. 2018 Sep 19;7(12):e1502129. doi: 10.1080/2162402X.2018.1502129. eCollection 2018.


Targeted Energy Intake Is the Important Determinant of Clinical Outcomes in Medical Critically Ill Patients with High Nutrition Risk.

Wang CY, Fu PK, Huang CT, Chen CH, Lee BJ, Huang YC.

Nutrients. 2018 Nov 11;10(11). pii: E1731. doi: 10.3390/nu10111731.


Erythropoietin reduces nerve demyelination, neuropathic pain behavior and microglial MAPKs activation through erythropoietin receptors on Schwann cells in a rat model of peripheral neuropathy.

Huang CT, Chen SH, Lin SC, Chen WT, Lue JH, Tsai YJ.

Glia. 2018 Nov;66(11):2299-2315. doi: 10.1002/glia.23461. Epub 2018 Nov 11.


Clinical characteristics of patients with laboratory-confirmed influenza A(H1N1)pdm09 during the 2013/2014 and 2015/2016 clade 6B/6B.1/6B.2-predominant outbreaks.

Hsieh YC, Tsao KC, Huang CT, Chang KY, Huang YC, Gong YN.

Sci Rep. 2018 Oct 23;8(1):15636. doi: 10.1038/s41598-018-34077-4.


Validity of ICD9-CM codes to diagnose chronic obstructive pulmonary disease from National Health Insurance claim data in Taiwan.

Ho TW, Ruan SY, Huang CT, Tsai YJ, Lai F, Yu CJ.

Int J Chron Obstruct Pulmon Dis. 2018 Oct 2;13:3055-3063. doi: 10.2147/COPD.S174265. eCollection 2018.


A Large-Scale Gene Expression Intensity-Based Similarity Metric for Drug Repositioning.

Huang CT, Hsieh CH, Oyang YJ, Huang HC, Juan HF.

iScience. 2018 Sep 28;7:40-52. doi: 10.1016/j.isci.2018.08.017. Epub 2018 Aug 23.


Atypical cells in pathology of endobronchial ultrasound-guided transbronchial biopsy of peripheral pulmonary lesions: incidence and clinical significance.

Huang CT, Tsai YJ, Ho CC, Yu CJ.

Surg Endosc. 2019 Jun;33(6):1783-1788. doi: 10.1007/s00464-018-6452-1. Epub 2018 Sep 10.


Small P particles formed by the Taiwan-native norovirus P domain overexpressed in Komagataella pastoris.

Chen YL, Chang PJ, Huang CT.

Appl Microbiol Biotechnol. 2018 Nov;102(22):9707-9718. doi: 10.1007/s00253-018-9331-8. Epub 2018 Sep 5.


SET Overexpression is Associated with Worse Recurrence-Free Survival in Patients with Primary Breast Cancer Receiving Adjuvant Tamoxifen Treatment.

Huang YH, Chu PY, Chen JL, Huang CT, Lee CH, Lau KY, Wang WL, Wang YL, Lien PJ, Tseng LM, Liu CY.

J Clin Med. 2018 Aug 28;7(9). pii: E245. doi: 10.3390/jcm7090245.


Cardiovascular Benefits of Acarbose vs Sulfonylureas in Patients With Type 2 Diabetes Treated With Metformin.

Hsu PF, Sung SH, Cheng HM, Shin SJ, Lin KD, Chong K, Yen FS, Yu BH, Huang CT, Hsu CC.

J Clin Endocrinol Metab. 2018 Oct 1;103(10):3611-3619. doi: 10.1210/jc.2018-00040.


Increased risk for major depressive disorder in severely obese patients after bariatric surgery - a 12-year nationwide cohort study.

Lu CW, Chang YK, Lee YH, Kuo CS, Chang HH, Huang CT, Hsu CC, Huang KC.

Ann Med. 2018 Nov;50(7):605-612. doi: 10.1080/07853890.2018.1511917. Epub 2018 Sep 7.


Empirical Bayesian Light-Field Stereo Matching by Robust Pseudo Random Field Modeling.

Huang CT.

IEEE Trans Pattern Anal Mach Intell. 2019 Mar;41(3):552-565. doi: 10.1109/TPAMI.2018.2809502. Epub 2018 Feb 26.


Reply to comment on: Ileocecal vascularized lymph node transfer for the treatment of extremity lymphedema: A case report.

Ciudad P, Manrique OJ, Agko M, Huang CT, Chang WL, Delgado B R, Reynaga C, Sacak B, Chen HC.

Microsurgery. 2018 Sep;38(6):723-724. doi: 10.1002/micr.30336. Epub 2018 Jul 4. No abstract available.


[Three-dimensional spatial measurement versus conventional CT planning in laparoscopic partial nephrectomy for renal tumors].

Hu ZF, Lv SD, Huang JF, Zhang L, Huang CT, Li YW, Huang WH, Ye JP, Wei Q.

Nan Fang Yi Ke Da Xue Xue Bao. 2018 May 20;38(5):606-611. Chinese.


Emetine inhibits Zika and Ebola virus infections through two molecular mechanisms: inhibiting viral replication and decreasing viral entry.

Yang S, Xu M, Lee EM, Gorshkov K, Shiryaev SA, He S, Sun W, Cheng YS, Hu X, Tharappel AM, Lu B, Pinto A, Farhy C, Huang CT, Zhang Z, Zhu W, Wu Y, Zhou Y, Song G, Zhu H, Shamim K, Martínez-Romero C, García-Sastre A, Preston RA, Jayaweera DT, Huang R, Huang W, Xia M, Simeonov A, Ming G, Qiu X, Terskikh AV, Tang H, Song H, Zheng W.

Cell Discov. 2018 Jun 5;4:31. doi: 10.1038/s41421-018-0034-1. eCollection 2018.

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