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Improved Microstructure and Hardness Properties of Low-Temperature Microwave-Sintered Y2O3 Stabilized ZrO2 Ceramics with Additions of Nano TiO2 Powders.

Weng MH, Lin CX, Huang CS, Tsai CY, Yang RY.

Materials (Basel). 2020 Mar 27;13(7). pii: E1546. doi: 10.3390/ma13071546.


Therapeutic Targeting of CDK7 Suppresses Tumor Progression in Intrahepatic Cholangiocarcinoma.

Chen HD, Huang CS, Xu QC, Li F, Huang XT, Wang JQ, Li SJ, Zhao W, Yin XY.

Int J Biol Sci. 2020 Feb 10;16(7):1207-1217. doi: 10.7150/ijbs.39779. eCollection 2020.


Bulging Tumor in the Distal Rectum.

Huang CS, Huang LK, Yang JD.

Gastroenterology. 2020 Mar 3. pii: S0016-5085(20)30276-6. doi: 10.1053/j.gastro.2020.02.049. [Epub ahead of print] No abstract available.


Benzyl isothiocyanate ameliorates high-fat/cholesterol/cholic acid diet-induced nonalcoholic steatohepatitis through inhibiting cholesterol crystal-activated NLRP3 inflammasome in Kupffer cells.

Chen HW, Yen CC, Kuo LL, Lo CW, Huang CS, Chen CC, Lii CK.

Toxicol Appl Pharmacol. 2020 Apr 15;393:114941. doi: 10.1016/j.taap.2020.114941. Epub 2020 Feb 29.


Electromagnetic navigation-guided versus computed tomography-guided percutaneous localization of small lung nodules before uniportal video-assisted thoracoscopic surgery: a propensity score-matched analysis.

Hung CT, Chen CK, Chang YY, Hsu PK, Hung JJ, Huang CS, Wu YC, Hsu HS.

Eur J Cardiothorac Surg. 2020 Feb 27. pii: ezz338. doi: 10.1093/ejcts/ezz338. [Epub ahead of print]


A Diterpenoid, 14-Deoxy-11, 12-Didehydroandrographolide, in Andrographis paniculata Reduces Steatohepatitis and Liver Injury in Mice Fed a High-Fat and High-Cholesterol Diet.

Liu YT, Chen HW, Lii CK, Jhuang JH, Huang CS, Li ML, Yao HT.

Nutrients. 2020 Feb 18;12(2). pii: E523. doi: 10.3390/nu12020523.


The Prognostic Impact of Extracapsular Lymph Node Involvement in Esophageal Squamous Cell Carcinoma.

Lin CM, Tu CC, Yeh YC, Hsu PK, Chien LI, Huang CS, Wu YC, Hsu HS.

Ann Surg Oncol. 2020 Feb 20. doi: 10.1245/s10434-020-08260-9. [Epub ahead of print]


Molecular Insight into Recognition of the CGRPR Complex by Migraine Prevention Therapy Aimovig (Erenumab).

Garces F, Mohr C, Zhang L, Huang CS, Chen Q, King C, Xu C, Wang Z.

Cell Rep. 2020 Feb 11;30(6):1714-1723.e6. doi: 10.1016/j.celrep.2020.01.029.


Surgeons' preference sublobar resection for stage I NSCLC less than 3 cm.

Huang CS, Hsu PK, Chen CK, Yeh YC, Hsu HS, Shih CC, Huang BS.

Thorac Cancer. 2020 Apr;11(4):907-917. doi: 10.1111/1759-7714.13336. Epub 2020 Feb 9.


Computer-aided diagnosis of breast ultrasound images using ensemble learning from convolutional neural networks.

Moon WK, Lee YW, Ke HH, Lee SH, Huang CS, Chang RF.

Comput Methods Programs Biomed. 2020 Jan 25;190:105361. doi: 10.1016/j.cmpb.2020.105361. [Epub ahead of print]


Computer-aided tumor detection in automated breast ultrasound using a 3-D convolutional neural network.

Moon WK, Huang YS, Hsu CH, Chang Chien TY, Chang JM, Lee SH, Huang CS, Chang RF.

Comput Methods Programs Biomed. 2020 Jan 25;190:105360. doi: 10.1016/j.cmpb.2020.105360. [Epub ahead of print]


Using next-generation sequencing to redefine BRCAness in triple-negative breast cancer.

Lin PH, Chen M, Tsai LW, Lo C, Yen TC, Huang TY, Chen CK, Fan SC, Kuo SH, Huang CS.

Cancer Sci. 2020 Jan 20. doi: 10.1111/cas.14313. [Epub ahead of print]


A network analysis to identify mediators of germline-driven differences in breast cancer prognosis.

Escala-Garcia M, Abraham J, Andrulis IL, Anton-Culver H, Arndt V, Ashworth A, Auer PL, Auvinen P, Beckmann MW, Beesley J, Behrens S, Benitez J, Bermisheva M, Blomqvist C, Blot W, Bogdanova NV, Bojesen SE, Bolla MK, Børresen-Dale AL, Brauch H, Brenner H, Brucker SY, Burwinkel B, Caldas C, Canzian F, Chang-Claude J, Chanock SJ, Chin SF, Clarke CL, Couch FJ, Cox A, Cross SS, Czene K, Daly MB, Dennis J, Devilee P, Dunn JA, Dunning AM, Dwek M, Earl HM, Eccles DM, Eliassen AH, Ellberg C, Evans DG, Fasching PA, Figueroa J, Flyger H, Gago-Dominguez M, Gapstur SM, García-Closas M, García-Sáenz JA, Gaudet MM, George A, Giles GG, Goldgar DE, González-Neira A, Grip M, Guénel P, Guo Q, Haiman CA, Håkansson N, Hamann U, Harrington PA, Hiller L, Hooning MJ, Hopper JL, Howell A, Huang CS, Huang G, Hunter DJ, Jakubowska A, John EM, Kaaks R, Kapoor PM, Keeman R, Kitahara CM, Koppert LB, Kraft P, Kristensen VN, Lambrechts D, Le Marchand L, Lejbkowicz F, Lindblom A, Lubiński J, Mannermaa A, Manoochehri M, Manoukian S, Margolin S, Martinez ME, Maurer T, Mavroudis D, Meindl A, Milne RL, Mulligan AM, Neuhausen SL, Nevanlinna H, Newman WG, Olshan AF, Olson JE, Olsson H, Orr N, Peterlongo P, Petridis C, Prentice RL, Presneau N, Punie K, Ramachandran D, Rennert G, Romero A, Sachchithananthan M, Saloustros E, Sawyer EJ, Schmutzler RK, Schwentner L, Scott C, Simard J, Sohn C, Southey MC, Swerdlow AJ, Tamimi RM, Tapper WJ, Teixeira MR, Terry MB, Thorne H, Tollenaar RAEM, Tomlinson I, Troester MA, Truong T, Turnbull C, Vachon CM, van der Kolk LE, Wang Q, Winqvist R, Wolk A, Yang XR, Ziogas A, Pharoah PDP, Hall P, Wessels LFA, Chenevix-Trench G, Bader GD, Dörk T, Easton DF, Canisius S, Schmidt MK.

Nat Commun. 2020 Jan 16;11(1):312. doi: 10.1038/s41467-019-14100-6.


The Antibacterial Efficacy and In Vivo Toxicity of Sodium Hypochlorite and Electrolyzed Oxidizing (EO) Water-Based Endodontic Irrigating Solutions.

Hsieh SC, Teng NC, Chu CC, Chu YT, Chen CH, Chang LY, Hsu CY, Huang CS, Hsiao GY, Yang JC.

Materials (Basel). 2020 Jan 7;13(2). pii: E260. doi: 10.3390/ma13020260.


Skeletofacial Reconstruction for Cleft-Related deformities: Four Decades of Evolving Cleft Care.

Denadai R, Chou PY, Pai BCJ, Chen C, Cheng-Hui Lin C, Huang CS, Chen YR, Lo LJ.

Ann Plast Surg. 2020 Jan 6. doi: 10.1097/SAP.0000000000002187. [Epub ahead of print]


Molecular mechanism of an antagonistic antibody against glucose-dependent insulinotropic polypeptide receptor.

Min X, Yie J, Wang J, Chung BC, Huang CS, Xu H, Yang J, Deng L, Lin J, Chen Q, Abbott CM, Gundel C, Thibault SA, Meng T, Bates DL, Lloyd DJ, Véniant MM, Wang Z.

MAbs. 2020 Jan-Dec;12(1):1710047. doi: 10.1080/19420862.2019.1710047.


Development and validation of a nomogram for predicting overall survival of node-negative ampullary carcinoma.

Huang XT, Huang CS, Chen W, Cai JP, Gan TT, Zhao Y, Liu Q, Liang LJ, Yin XY.

J Surg Oncol. 2020 Mar;121(3):518-523. doi: 10.1002/jso.25816. Epub 2019 Dec 26.


Preoperative biopsy and tumor recurrence of stage I adenocarcinoma of the lung.

Huang CS, Hsu PK, Chen CK, Yeh YC, Chen HS, Wu MH, Chou TY, Hsu WH, Shih CC, Huang BS.

Surg Today. 2019 Dec 23. doi: 10.1007/s00595-019-01941-3. [Epub ahead of print]


Disruption of Cancer Metabolic SREBP1/miR-142-5p Suppresses Epithelial-Mesenchymal Transition and Stemness in Esophageal Carcinoma.

Huang CM, Huang CS, Hsu TN, Huang MS, Fong IH, Lee WH, Liu SC.

Cells. 2019 Dec 18;9(1). pii: E7. doi: 10.3390/cells9010007.


Epigenetic Inactivation of SOX30 Is Associated with Male Infertility and Offers a Therapy Target for Non-obstructive Azoospermia.

Han F, Jiang X, Li ZM, Zhuang X, Zhang X, Ouyang WM, Liu WB, Mao CY, Chen Q, Huang CS, Gao F, Cui ZH, Ao L, Li YF, Cao J, Liu JY.

Mol Ther Nucleic Acids. 2020 Mar 6;19:72-83. doi: 10.1016/j.omtn.2019.10.038. Epub 2019 Nov 14.


History and Evolution of Orthognathic Surgery at Chang Gung Craniofacial Center: Lessons Learned From 35-Year Experience.

Chou PY, Denadai R, Yao CF, Chen YA, Chang CS, Lin CC, Liao YF, Liou EJW, Ko EW, Lo LJ, Huang CS, Chen YR.

Ann Plast Surg. 2020 Jan;84(1S Suppl 1):S60-S68. doi: 10.1097/SAP.0000000000002179.


CircularRNA as novel biomarkers in liver diseases.

Chien Y, Tsai PH, Lai YH, Lu KH, Liu CY, Lin HF, Huang CS, Wu WW, Wang CY.

J Chin Med Assoc. 2020 Jan;83(1):15-17. doi: 10.1097/JCMA.0000000000000230.


Complications after Chest Tube Removal and Reinterventions in Patients with Digital Drainage Systems.

Lee YY, Hsu PK, Huang CS, Wu YC, Hsu HS.

J Clin Med. 2019 Dec 1;8(12). pii: E2092. doi: 10.3390/jcm8122092.


Targeting FAT1 Inhibits Carcinogenesis, Induces Oxidative Stress and Enhances Cisplatin Sensitivity through Deregulation of LRP5/WNT2/GSS Signaling Axis in Oral Squamous Cell Carcinoma.

Hsu TN, Huang CM, Huang CS, Huang MS, Yeh CT, Chao TY, Bamodu OA.

Cancers (Basel). 2019 Nov 27;11(12). pii: E1883. doi: 10.3390/cancers11121883.


Dissecting the molecular basis of high viscosity of monospecific and bispecific IgG antibodies.

Tilegenova C, Izadi S, Yin J, Huang CS, Wu J, Ellerman D, Hymowitz SG, Walters B, Salisbury C, Carter PJ.

MAbs. 2020 Jan-Dec;12(1):1692764. doi: 10.1080/19420862.2019.1692764.


MFAP5 facilitates the aggressiveness of intrahepatic Cholangiocarcinoma by activating the Notch1 signaling pathway.

Li JH, Zhu XX, Li FX, Huang CS, Huang XT, Wang JQ, Gao ZX, Li SJ, Xu QC, Zhao W, Yin XY.

J Exp Clin Cancer Res. 2019 Nov 27;38(1):476. doi: 10.1186/s13046-019-1477-4.


The project ENABLE Cornerstone randomized pilot trial: Protocol for lay navigator-led early palliative care for African-American and rural advanced cancer family caregivers.

Hendricks BA, Lofton C, Azuero A, Kenny M, Taylor RA, Huang CS, Rocque G, Williams GR, Dosse C, Louis K, Bakitas MA, Dionne-Odom JN.

Contemp Clin Trials Commun. 2019 Nov 12;16:100485. doi: 10.1016/j.conctc.2019.100485. eCollection 2019 Dec.


A comprehensive study comparing tack and glue mesh fixation in laparoscopic total extraperitoneal repair for adult groin hernias.

Yu CC, Chen YT, Huang CS, Chueh SJ, Lo CW, Tsai YC.

Surg Endosc. 2019 Nov 18. doi: 10.1007/s00464-019-07234-7. [Epub ahead of print]


Pathological complete response after afatinib treatment of stage IV oligometastatic adenocarcinoma of the lung: the role of pulmonary surgery.

Tsai PC, Yeh YC, Huang CS, Chiu CH.

Surg Case Rep. 2019 Nov 12;5(1):178. doi: 10.1186/s40792-019-0741-3.


Association of cyclophilin A level and pulse pressure in predicting recurrence of cerebral infarction.

Chang CS, Kuo CL, Huang CS, Cheng YS, Lin SS, Liu CS.

Kaohsiung J Med Sci. 2020 Feb;36(2):122-128. doi: 10.1002/kjm2.12143. Epub 2019 Oct 31.


Urinary cell-free mitochondrial and nuclear deoxyribonucleic acid correlates with the prognosis of chronic kidney diseases.

Chang CC, Chiu PF, Wu CL, Kuo CL, Huang CS, Liu CS, Huang CH.

BMC Nephrol. 2019 Oct 28;20(1):391. doi: 10.1186/s12882-019-1549-x.


Potent Cell-Cycle Inhibition and Upregulation of Immune Response with Abemaciclib and Anastrozole in neoMONARCH, Phase II Neoadjuvant Study in HR+/HER2- Breast Cancer.

Hurvitz SA, Martin M, Press MF, Chan D, Fernandez-Abad M, Petru E, Rostorfer R, Guarneri V, Huang CS, Barriga S, Wijayawardana S, Brahmachary M, Ebert PJ, Hossain A, Liu J, Abel A, Aggarwal A, Jansen VM, Slamon DJ.

Clin Cancer Res. 2020 Feb 1;26(3):566-580. doi: 10.1158/1078-0432.CCR-19-1425. Epub 2019 Oct 15.


[Effect of Silencing and Overexpression of LNK Gene on STAT3 Expression in THP-1 Cells].

Tian RM, Shi L, Rong Y, Tan M, Luo X, Su Q, Huang CS, Chen Y.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019 Oct;27(5):1469-1475. doi: 10.19746/j.cnki.issn.1009-2137.2019.05.018. Chinese.


The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.

Oberbeck N, Pham VC, Webster JD, Reja R, Huang CS, Zhang Y, Roose-Girma M, Warming S, Li Q, Birnberg A, Wong W, Sandoval W, Kőműves LG, Yu K, Dugger DL, Maltzman A, Newton K, Dixit VM.

Nature. 2019 Oct;574(7777):249-253. doi: 10.1038/s41586-019-1615-3. Epub 2019 Oct 2.


Anti-Inflammatory Effect of Erinacine C on NO Production Through Down-Regulation of NF-κB and Activation of Nrf2-Mediated HO-1 in BV2 Microglial Cells Treated with LPS.

Wang LY, Huang CS, Chen YH, Chen CC, Chen CC, Chuang CH.

Molecules. 2019 Sep 12;24(18). pii: E3317. doi: 10.3390/molecules24183317.


1,25(OH)2 D3 attenuates indoxyl sulfate-induced epithelial-to-mesenchymal cell transition via inactivation of PI3K/Akt/β-catenin signaling in renal tubular epithelial cells.

Chang LC, Sun HL, Tsai CH, Kuo CW, Liu KL, Lii CK, Huang CS, Li CC.

Nutrition. 2020 Jan;69:110554. doi: 10.1016/j.nut.2019.110554. Epub 2019 Jul 25.


The compressive strength of implant-abutment complex with different connection designs.

Hung HC, Huang CS, Pan YH.

J Dent Sci. 2019 Sep;14(3):318-324. doi: 10.1016/j.jds.2019.01.014. Epub 2019 Mar 28.


Docosahexaenoic acid inhibits TNFα-induced ICAM-1 expression by activating PPARα and autophagy in human endothelial cells.

Lin HC, Lii CK, Lin AH, Li CC, Tsai CH, Pan SK, Yang YC, Huang CS, Reshi L, Chen HW.

Food Chem Toxicol. 2019 Dec;134:110811. doi: 10.1016/j.fct.2019.110811. Epub 2019 Sep 6.


[EPO and EPOR Expression in Patients with Acute Leukemia and Its Clinical Significance].

Tian RM, Huang CS, Su Q, Shi L, Luo X, Chen Y.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019 Aug;27(4):1026-1032. doi: 10.19746/j.cnki.issn.1009-2137.2019.04.006. Chinese.


[Effect of Silencing LNK Gene on the Expression of EPO and EPOR in THP-1 Cells].

Tian RM, Luo X, Tan M, Shi L, Huang CS, Su Q, Chen Y.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2019 Aug;27(4):1013-1019. doi: 10.19746/j.cnki.issn.1009-2137.2019.04.004. Chinese.


EYA4 inhibits hepatocellular carcinoma by repressing MYCBP by dephosphorylating β-catenin at Ser552.

Zhu XX, Li JH, Cai JP, Hou X, Huang CS, Huang XT, Wang JQ, Li SJ, Xu QC, Yin XY.

Cancer Sci. 2019 Oct;110(10):3110-3121. doi: 10.1111/cas.14159. Epub 2019 Aug 28.


Disparity in Tumor Immune Microenvironment of Breast Cancer and Prognostic Impact: Asian Versus Western Populations.

Chen CH, Lu YS, Cheng AL, Huang CS, Kuo WH, Wang MY, Chao M, Chen IC, Kuo CW, Lu TP, Lin CH.

Oncologist. 2020 Jan;25(1):e16-e23. doi: 10.1634/theoncologist.2019-0123. Epub 2019 Aug 1.


Clinical Evaluation of IntelliPlex™ KRAS G12/13 Mutation Kit for Detection of KRAS Mutations in Codon 12 and 13: A Novel Multiplex Approach.

Chen CL, Chen CK, Ho CL, Chi WM, Yeh CH, Hu SP, Friebe P, Palmer S, Huang CS.

Mol Diagn Ther. 2019 Oct;23(5):645-656. doi: 10.1007/s40291-019-00418-w.


Repeated transcutaneous electrical nerve stimulation of nonspecific acupoints of the upper body attenuates stress-induced visceral hypersensitivity in rats.

Huang CS, Sun YH, Wang YT, Pan YH, Huang YC, Hsu CM, Tsai YF.

Auton Neurosci. 2019 Sep;220:102556. doi: 10.1016/j.autneu.2019.102556. Epub 2019 Jun 4.


A preliminary report of head-to-head comparison of 18-gene-based clinical-genomic model and oncotype DX 21-gene assay for predicting recurrence of early-stage breast cancer.

Yang PS, Lee YH, Chung CF, Chang YC, Wang MY, Lo C, Tsai LW, Shih KH, Lei J, Yu BL, Cheng SH, Huang CS.

Jpn J Clin Oncol. 2019 Dec 18;49(11):1029-1036. doi: 10.1093/jjco/hyz102.


Benzyl Isothiocyanate and Phenethyl Isothiocyanate Inhibit Adipogenesis and Hepatosteatosis in Mice with Obesity Induced by a High-Fat Diet.

Chuang WT, Liu YT, Huang CS, Lo CW, Yao HT, Chen HW, Lii CK.

J Agric Food Chem. 2019 Jun 26;67(25):7136-7146. doi: 10.1021/acs.jafc.9b02668. Epub 2019 Jun 18.


Discovery of a Lead Triphenylethanamine Cholesterol Ester Transfer Protein (CETP) Inhibitor.

Finlay HJ, Jiang J, Rampulla R, Salvati ME, Qiao JX, Wang TC, Lawrence RM, Harikrishnan LS, Kamau MG, Taylor DS, Chen AYA, Yin X, Huang CS, Chang M, Chen XQ, Sleph PG, Xu C, Li J, Levesque P, Adam LP, Wexler RR.

ACS Med Chem Lett. 2019 May 6;10(6):911-916. doi: 10.1021/acsmedchemlett.9b00086. eCollection 2019 Jun 13.


Ki-67 Index of 5% is Better Than 2% in Stratifying G1 and G2 of the World Health Organization Grading System in Pancreatic Neuroendocrine Tumors.

Gao SW, Huang CS, Huang XT, Chen LH, Chen W, Cai JP, Yin XY.

Pancreas. 2019 Jul;48(6):795-798. doi: 10.1097/MPA.0000000000001331.


Neoadjuvant Trastuzumab Emtansine and Pertuzumab in Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: Three-Year Outcomes From the Phase III KRISTINE Study.

Hurvitz SA, Martin M, Jung KH, Huang CS, Harbeck N, Valero V, Stroyakovskiy D, Wildiers H, Campone M, Boileau JF, Fasching PA, Afenjar K, Spera G, Lopez-Valverde V, Song C, Trask P, Boulet T, Sparano JA, Symmans WF, Thompson AM, Slamon D.

J Clin Oncol. 2019 Sep 1;37(25):2206-2216. doi: 10.1200/JCO.19.00882. Epub 2019 Jun 3.


Air Pollutants Are Associated With Obstructive Sleep Apnea Severity in Non-Rapid Eye Movement Sleep.

Cheng WJ, Liang SJ, Huang CS, Lin CL, Pien LC, Hang LW.

J Clin Sleep Med. 2019 Jun 15;15(6):831-837. doi: 10.5664/jcsm.7830.


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