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Items: 1 to 50 of 176

1.

Front-line treatment of ceritinib improves efficacy over crizotinib for Asian patients with anaplastic lymphoma kinase fusion NSCLC: The role of systemic progression control.

Huang SH, Huang AC, Wang CC, Chang WC, Liu CY, Pavlidis S, Ko HW, Chung FT, Hsu PC, Guo YK, Kuo CS, Yang CT.

Thorac Cancer. 2019 Oct 15. doi: 10.1111/1759-7714.13221. [Epub ahead of print]

PMID:
31613427
2.

TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision.

Chen Z, Ji Z, Ngiow SF, Manne S, Cai Z, Huang AC, Johnson J, Staupe RP, Bengsch B, Xu C, Yu S, Kurachi M, Herati RS, Vella LA, Baxter AE, Wu JE, Khan O, Beltra JC, Giles JR, Stelekati E, McLane LM, Lau CW, Yang X, Berger SL, Vahedi G, Ji H, Wherry EJ.

Immunity. 2019 Oct 7. pii: S1074-7613(19)30409-1. doi: 10.1016/j.immuni.2019.09.013. [Epub ahead of print]

PMID:
31606264
3.

Involvement of neural substrates in reward and aversion to methamphetamine addiction: Testing the reward comparison hypothesis and the paradoxical effect hypothesis of abused drugs.

He ABH, Huang CL, Kozłowska A, Chen JC, Wu CW, Huang ACW, Liu YQ.

Neurobiol Learn Mem. 2019 Sep 12;166:107090. doi: 10.1016/j.nlm.2019.107090. [Epub ahead of print]

PMID:
31521799
4.

TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion.

Khan O, Giles JR, McDonald S, Manne S, Ngiow SF, Patel KP, Werner MT, Huang AC, Alexander KA, Wu JE, Attanasio J, Yan P, George SM, Bengsch B, Staupe RP, Donahue G, Xu W, Amaravadi RK, Xu X, Karakousis GC, Mitchell TC, Schuchter LM, Kaye J, Berger SL, Wherry EJ.

Nature. 2019 Jul;571(7764):211-218. doi: 10.1038/s41586-019-1325-x. Epub 2019 Jun 17.

PMID:
31207603
5.

Fisetin Inhibits Cell Proliferation through the Induction of G0/G1 Phase Arrest and Caspase-3-Mediated Apoptosis in Mouse Leukemia Cells.

Tsai YH, Lin JJ, Ma YS, Peng SF, Huang AC, Huang YP, Fan MJ, Lien JC, Chung JG.

Am J Chin Med. 2019;47(4):841-863. doi: 10.1142/S0192415X19500447. Epub 2019 May 16.

PMID:
31096772
6.

A specialized metabolic network selectively modulates Arabidopsis root microbiota.

Huang AC, Jiang T, Liu YX, Bai YC, Reed J, Qu B, Goossens A, Nützmann HW, Bai Y, Osbourn A.

Science. 2019 May 10;364(6440). pii: eaau6389. doi: 10.1126/science.aau6389.

PMID:
31073042
7.

Fistein Suppresses Human Osteosarcoma U-2 OS Cell Migration and Invasion via Affecting FAK, uPA and NF-ĸB Signaling Pathway In Vitro.

Chen JK, Peng SF, Lai KC, Liu HC, Huang YP, Lin CC, Huang AC, Chueh FS, Chung JG.

In Vivo. 2019 May-Jun;33(3):801-810. doi: 10.21873/invivo.11542.

8.

Casticin Induces DNA Damage and Impairs DNA Repair in Human Bladder Cancer TSGH-8301 Cells.

Huang AC, Cheng YD, Huang LH, Hsiao YT, Peng SF, Lu KW, Lien JC, Yang JL, Lin TS, Chung JG.

Anticancer Res. 2019 Apr;39(4):1839-1847. doi: 10.21873/anticanres.13291.

PMID:
30952724
9.

Plant terpenes that mediate below-ground interactions: prospects for bioengineering terpenoids for plant protection.

Huang AC, Osbourn A.

Pest Manag Sci. 2019 Sep;75(9):2368-2377. doi: 10.1002/ps.5410. Epub 2019 Apr 8. Review.

10.

Lateral Field Excitation of Thickness Longitudinal Mode and Shear Mode With ZnO Based on Solidly Mounted Resonator.

Meng SH, Huang AC, Chen YC, Yuan C.

IEEE Trans Ultrason Ferroelectr Freq Control. 2019 May;66(5):1014-1021. doi: 10.1109/TUFFC.2019.2903189. Epub 2019 Mar 5.

PMID:
30843829
11.

Molecular interaction of the antiviral compound CW‑33 and its analogues with the NS2B‑NS3 protease of the Japanese encephalitis virus.

Chen KC, Lin YF, Huang AC, Gao JY, Lin CW, Lien JC.

Int J Mol Med. 2019 May;43(5):2024-2032. doi: 10.3892/ijmm.2019.4113. Epub 2019 Feb 27.

12.

A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma.

Huang AC, Orlowski RJ, Xu X, Mick R, George SM, Yan PK, Manne S, Kraya AA, Wubbenhorst B, Dorfman L, D'Andrea K, Wenz BM, Liu S, Chilukuri L, Kozlov A, Carberry M, Giles L, Kier MW, Quagliarello F, McGettigan S, Kreider K, Annamalai L, Zhao Q, Mogg R, Xu W, Blumenschein WM, Yearley JH, Linette GP, Amaravadi RK, Schuchter LM, Herati RS, Bengsch B, Nathanson KL, Farwell MD, Karakousis GC, Wherry EJ, Mitchell TC.

Nat Med. 2019 Mar;25(3):454-461. doi: 10.1038/s41591-019-0357-y. Epub 2019 Feb 25.

13.

ADHD pathogenesis in the immune, endocrine and nervous systems of juvenile and maturating SHR and WKY rats.

Kozłowska A, Wojtacha P, Równiak M, Kolenkiewicz M, Huang ACW.

Psychopharmacology (Berl). 2019 Feb 8. doi: 10.1007/s00213-019-5180-0. [Epub ahead of print]

PMID:
30737597
14.

Thermal Decomposition and Nonisothermal Kinetics of Monoethanolamine Mixed with Various Metal Ions.

Wei M, Huang AC, Shu CM, Zhang L.

Sci Rep. 2019 Feb 7;9(1):1592. doi: 10.1038/s41598-018-38434-1.

15.

Bufalin Induces Apoptotic Cell Death in Human Nasopharyngeal Carcinoma Cells through Mitochondrial ROS and TRAIL Pathways.

Su EY, Chu YL, Chueh FS, Ma YS, Peng SF, Huang WW, Liao CL, Huang AC, Chung JG.

Am J Chin Med. 2019;47(1):237-257. doi: 10.1142/S0192415X19500125. Epub 2019 Jan 7.

PMID:
30612454
16.

Neuronal nitric oxide synthase activity mediates Lycium barbarum polysaccharides-enhanced sexual performance without stimulating noncontact erection in rats.

Huang AC, Wu JM, Chang YH, Dubey NK, Chiu AW, Yeh CY, Tsai TH, Yeh KY.

Psychopharmacology (Berl). 2019 Apr;236(4):1293-1301. doi: 10.1007/s00213-018-5141-z. Epub 2018 Dec 11.

PMID:
30539267
17.

Structure analysis and antiviral activity of CW-33 analogues against Japanese encephalitis virus.

Lien JC, Wang CY, Lai HC, Lu CY, Lin YF, Gao GY, Chen KC, Huang AC, Huang SH, Lin CW.

Sci Rep. 2018 Nov 9;8(1):16595. doi: 10.1038/s41598-018-34932-4.

18.

A phase I trial of pembrolizumab with hypofractionated radiotherapy in patients with metastatic solid tumours.

Maity A, Mick R, Huang AC, George SM, Farwell MD, Lukens JN, Berman AT, Mitchell TC, Bauml J, Schuchter LM, O'Hara M, Lin LL, Demichele A, Christodouleas JP, Haas NB, Patsch DM, Hahn SM, Minn AJ, Wherry EJ, Vonderheide RH.

Br J Cancer. 2018 Nov;119(10):1200-1207. doi: 10.1038/s41416-018-0281-9. Epub 2018 Oct 15.

19.

Central Poststroke Pain, Comorbidity, and Associated Symptoms in Animal and Human Models.

Shyu BC, Huang ACW.

Adv Exp Med Biol. 2018;1099:253-265. doi: 10.1007/978-981-13-1756-9_20. Review.

PMID:
30306529
20.

Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity.

Zappasodi R, Budhu S, Hellmann MD, Postow MA, Senbabaoglu Y, Manne S, Gasmi B, Liu C, Zhong H, Li Y, Huang AC, Hirschhorn-Cymerman D, Panageas KS, Wherry EJ, Merghoub T, Wolchok JD.

Cancer Cell. 2018 Oct 8;34(4):691. doi: 10.1016/j.ccell.2018.09.007. No abstract available.

21.

Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma.

Bajor DL, Mick R, Riese MJ, Huang AC, Sullivan B, Richman LP, Torigian DA, George SM, Stelekati E, Chen F, Melenhorst JJ, Lacey SF, Xu X, Wherry EJ, Gangadhar TC, Amaravadi RK, Schuchter LM, Vonderheide RH.

Oncoimmunology. 2018 Aug 20;7(10):e1468956. doi: 10.1080/2162402X.2018.1468956. eCollection 2018.

22.

Motor function in an animal model with ouabain-induced bipolar disorder and comorbid anxiety behavior.

Wang YC, Yu YH, Tsai ML, Huang ACW.

Psychiatry Res. 2018 Oct;268:508-513. doi: 10.1016/j.psychres.2018.07.031. Epub 2018 Jul 26.

PMID:
30165326
23.

Berberine Inhibits Human Melanoma A375.S2 Cell Migration and Invasion via Affecting the FAK, uPA, and NF-κB Signaling Pathways and Inhibits PLX4032 Resistant A375.S2 Cell Migration In Vitro.

Liu JF, Lai KC, Peng SF, Maraming P, Huang YP, Huang AC, Chueh FS, Huang WW, Chung JG.

Molecules. 2018 Aug 13;23(8). pii: E2019. doi: 10.3390/molecules23082019.

24.

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response.

Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W.

Nature. 2018 Aug;560(7718):382-386. doi: 10.1038/s41586-018-0392-8. Epub 2018 Aug 8.

25.

Investigation of Interactive Activity of Electro-Acupuncture on Pharmacokinetics of Sildenafil and Their Synergistic Effect on Penile Blood Flow in Rats.

Huang AC, Yeh KY, Cheng YY, Dubey NK, Chiu AW, Tsai TH.

Int J Mol Sci. 2018 Jul 24;19(8). pii: E2153. doi: 10.3390/ijms19082153.

26.

Bisdemethoxycurcumin Suppresses Migration and Invasion of Human Cervical Cancer HeLa Cells via Inhibition of NF-ĸB, MMP-2 and -9 Pathways.

Liao CL, Chu YL, Lin HY, Chen CY, Hsu MJ, Liu KC, Lai KC, Huang AC, Chung JG.

Anticancer Res. 2018 Jul;38(7):3989-3997. doi: 10.21873/anticanres.12686.

PMID:
29970522
27.

Corrigendum re: "The Impact of Prostate Size, Median Lobe, and Prior Benign Prostatic Hyperplasia Intervention on Robot-Assisted Laparoscopic Prostatectomy: Technique and Outcomes" [Eur Urol 2011;59:595-603].

Huang AC, Kowalczyk KJ, Hevelone ND, Lipsitz SR, Yu HY, Plaster BA, Amarasekera CA, Ulmer WD, Lei Y, Williams SB, Hu JC.

Eur Urol. 2018 Nov;74(5):e129. doi: 10.1016/j.eururo.2018.06.015. Epub 2018 Jun 25. No abstract available.

PMID:
29954614
28.

Synergistic Antitumor Effect of Oligogalacturonides and Cisplatin on Human Lung Cancer A549 Cells.

Huang CS, Huang AC, Huang PH, Lo D, Wang YT, Wu MC.

Int J Mol Sci. 2018 Jun 14;19(6). pii: E1769. doi: 10.3390/ijms19061769.

29.

Non-conventional Inhibitory CD4+Foxp3-PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity.

Zappasodi R, Budhu S, Hellmann MD, Postow MA, Senbabaoglu Y, Manne S, Gasmi B, Liu C, Zhong H, Li Y, Huang AC, Hirschhorn-Cymerman D, Panageas KS, Wherry EJ, Merghoub T, Wolchok JD.

Cancer Cell. 2018 Jun 11;33(6):1017-1032.e7. doi: 10.1016/j.ccell.2018.05.009. Erratum in: Cancer Cell. 2018 Oct 8;34(4):691.

30.

Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells.

Bengsch B, Ohtani T, Khan O, Setty M, Manne S, O'Brien S, Gherardini PF, Herati RS, Huang AC, Chang KM, Newell EW, Bovenschen N, Pe'er D, Albelda SM, Wherry EJ.

Immunity. 2018 May 15;48(5):1029-1045.e5. doi: 10.1016/j.immuni.2018.04.026.

31.

Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia.

Fraietta JA, Lacey SF, Orlando EJ, Pruteanu-Malinici I, Gohil M, Lundh S, Boesteanu AC, Wang Y, O'Connor RS, Hwang WT, Pequignot E, Ambrose DE, Zhang C, Wilcox N, Bedoya F, Dorfmeier C, Chen F, Tian L, Parakandi H, Gupta M, Young RM, Johnson FB, Kulikovskaya I, Liu L, Xu J, Kassim SH, Davis MM, Levine BL, Frey NV, Siegel DL, Huang AC, Wherry EJ, Bitter H, Brogdon JL, Porter DL, June CH, Melenhorst JJ.

Nat Med. 2018 May;24(5):563-571. doi: 10.1038/s41591-018-0010-1. Epub 2018 Apr 30.

32.

River otters (Lontra canadensis) "trapped" in a coastal environment contaminated with persistent organic pollutants: Demographic and physiological consequences.

Huang AC, Nelson C, Elliott JE, Guertin DA, Ritland C, Drouillard K, Cheng KM, Schwantje HM.

Environ Pollut. 2018 Jul;238:306-316. doi: 10.1016/j.envpol.2018.03.035. Epub 2018 Mar 22.

33.

Direct-acting antivirals do not increase the risk of hepatocellular carcinoma recurrence after local-regional therapy or liver transplant waitlist dropout.

Huang AC, Mehta N, Dodge JL, Yao FY, Terrault NA.

Hepatology. 2018 Aug;68(2):449-461. doi: 10.1002/hep.29855. Epub 2018 May 16.

34.

Deguelin Impairs Cell Adhesion, Migration and Invasion of Human Lung Cancer Cells through the NF-[Formula: see text]B Signaling Pathways.

Hsiao YT, Fan MJ, Huang AC, Lien JC, Lin JJ, Chen JC, Hsia TC, Wu RS, Chung JG.

Am J Chin Med. 2018;46(1):209-229. doi: 10.1142/S0192415X1850012X.

PMID:
29402127
35.

Mapping and Quantification of Over 2000 O-linked Glycopeptides in Activated Human T Cells with Isotope-Targeted Glycoproteomics (Isotag).

Woo CM, Lund PJ, Huang AC, Davis MM, Bertozzi CR, Pitteri SJ.

Mol Cell Proteomics. 2018 Apr;17(4):764-775. doi: 10.1074/mcp.RA117.000261. Epub 2018 Jan 19.

36.

Diverged Plant Terpene Synthases Reroute the Carbocation Cyclization Path towards the Formation of Unprecedented 6/11/5 and 6/6/7/5 Sesterterpene Scaffolds.

Huang AC, Hong YJ, Bond AD, Tantillo DJ, Osbourn A.

Angew Chem Int Ed Engl. 2018 Jan 26;57(5):1291-1295. doi: 10.1002/anie.201711444. Epub 2017 Dec 28.

37.

Location of Cerebral Microbleeds And Their Association with Carotid Intima-media Thickness: A Community-based Study.

Chung CP, Chou KH, Chen WT, Liu LK, Lee WJ, Huang AC, Chen LK, Lin CP, Wang PN.

Sci Rep. 2017 Sep 21;7(1):12058. doi: 10.1038/s41598-017-12176-y.

38.

A Rare Phenotype of Alpha-1-Antitrypsin Deficiency Owing to PI*IS in a Newborn With Liver Disease.

Huang AC, Perez C, Felipez L, Chamyan G, Finegold MJ, Hernandez E.

J Pediatr Gastroenterol Nutr. 2017 Nov;65(5):e112-e113. doi: 10.1097/MPG.0000000000001716. No abstract available.

PMID:
28837509
39.

Discrepancies between leg-to-leg bioelectrical Impedance analysis and computerized tomography in abdominal visceral fat measurement.

Lu HK, Chen YY, Yeh C, Chuang CL, Chiang LM, Lai CL, Casebolt KM, Huang AC, Lin WL, Hsieh KC.

Sci Rep. 2017 Aug 22;7(1):9102. doi: 10.1038/s41598-017-08991-y.

40.

Wind conditions on migration influence the annual survival of a neotropical migrant, the western yellow-breasted chat (Icteria virens auricollis).

Huang AC, Bishop CA, McKibbin R, Drake A, Green DJ.

BMC Ecol. 2017 Aug 10;17(1):29. doi: 10.1186/s12898-017-0139-7.

41.

Feasibility of monitoring advanced melanoma patients using cell-free DNA from plasma.

Gangadhar TC, Savitch SL, Yee SS, Xu W, Huang AC, Harmon S, Lieberman DB, Soucier D, Fan R, Black TA, Morrissette JJD, Salathia N, Waters J, Zhang S, Toung J, van Hummelen P, Fan JB, Xu X, Amaravadi RK, Schuchter LM, Karakousis GC, Hwang WT, Carpenter EL.

Pigment Cell Melanoma Res. 2018 Jan;31(1):73-81. doi: 10.1111/pcmr.12623. Epub 2017 Oct 23.

42.

Cantharidin alters the expression of genes associated with the NKG2D-associated immune response in TSGH-8301 human bladder carcinoma cells.

Kuo JH, Huang AC, Lin JJ, Lai KC, Wu RS, Yang JL, Ji BC, Yang MD, Chu YL, Chung JG.

Oncol Lett. 2017 Jul;14(1):234-240. doi: 10.3892/ol.2017.6168. Epub 2017 May 12.

43.

Unearthing a sesterterpene biosynthetic repertoire in the Brassicaceae through genome mining reveals convergent evolution.

Huang AC, Kautsar SA, Hong YJ, Medema MH, Bond AD, Tantillo DJ, Osbourn A.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E6005-E6014. doi: 10.1073/pnas.1705567114. Epub 2017 Jul 3.

44.

Anthocyanins from black rice (Oryza sativa) promote immune responses in leukemia through enhancing phagocytosis of macrophages in vivo.

Fan MJ, Yeh PH, Lin JP, Huang AC, Lien JC, Lin HY, Chung JG.

Exp Ther Med. 2017 Jul;14(1):59-64. doi: 10.3892/etm.2017.4467. Epub 2017 May 17.

45.

An examination of the roles of glutamate and sex in latent inhibition: Relevance to the glutamate hypothesis of schizophrenia?

Huang ACW, Bo-Han He A, Chen CC.

Psychiatry Res. 2017 Oct;256:46-52. doi: 10.1016/j.psychres.2017.06.033. Epub 2017 Jun 12.

PMID:
28623767
46.

Re-evaluation of the reward comparison hypothesis for alcohol abuse.

He AB, Chang YC, Meng AWY, Huang ACW.

Behav Brain Res. 2017 Aug 14;332:218-222. doi: 10.1016/j.bbr.2017.06.006. Epub 2017 Jun 9.

PMID:
28606627
47.

Social factors affect motor and anxiety behaviors in the animal model of attention-deficit hyperactivity disorders: A housing-style factor.

Tsai ML, Kozłowska A, Li YS, Shen WL, Huang ACW.

Psychiatry Res. 2017 Aug;254:290-300. doi: 10.1016/j.psychres.2017.05.008. Epub 2017 May 6.

PMID:
28501734
48.

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response.

Huang AC, Postow MA, Orlowski RJ, Mick R, Bengsch B, Manne S, Xu W, Harmon S, Giles JR, Wenz B, Adamow M, Kuk D, Panageas KS, Carrera C, Wong P, Quagliarello F, Wubbenhorst B, D'Andrea K, Pauken KE, Herati RS, Staupe RP, Schenkel JM, McGettigan S, Kothari S, George SM, Vonderheide RH, Amaravadi RK, Karakousis GC, Schuchter LM, Xu X, Nathanson KL, Wolchok JD, Gangadhar TC, Wherry EJ.

Nature. 2017 May 4;545(7652):60-65. doi: 10.1038/nature22079. Epub 2017 Apr 10.

49.

Blood Beta-Amyloid and Tau in Down Syndrome: A Comparison with Alzheimer's Disease.

Lee NC, Yang SY, Chieh JJ, Huang PT, Chang LM, Chiu YN, Huang AC, Chien YH, Hwu WL, Chiu MJ.

Front Aging Neurosci. 2017 Jan 17;8:316. doi: 10.3389/fnagi.2016.00316. eCollection 2016.

50.

Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade.

Benci JL, Xu B, Qiu Y, Wu TJ, Dada H, Twyman-Saint Victor C, Cucolo L, Lee DSM, Pauken KE, Huang AC, Gangadhar TC, Amaravadi RK, Schuchter LM, Feldman MD, Ishwaran H, Vonderheide RH, Maity A, Wherry EJ, Minn AJ.

Cell. 2016 Dec 1;167(6):1540-1554.e12. doi: 10.1016/j.cell.2016.11.022.

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