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Seizure remission and improvement of neurological function in sialidosis with perampanel therapy.

Hu SC, Hung KL, Chen HJ, Lee WT.

Epilepsy Behav Case Rep. 2018 Mar 12;10:32-34. doi: 10.1016/j.ebcr.2018.02.005. eCollection 2018.


Analysis of metabolic profiles of generalized aggressive periodontitis.

Chen HW, Zhou W, Liao Y, Hu SC, Chen TL, Song ZC.

J Periodontal Res. 2018 Jul 4. doi: 10.1111/jre.12579. [Epub ahead of print]


I-123 DaTscan SPECT Brain Imaging in Parkinsonian Syndromes: Utility of the Putamen-to-Caudate Ratio.

Matesan M, Gaddikeri S, Longfellow K, Miyaoka R, Elojeimy S, Elman S, Hu SC, Minoshima S, Lewis D.

J Neuroimaging. 2018 Jun 14. doi: 10.1111/jon.12530. [Epub ahead of print]


Successful Treatment of Holmes Tremor With Deep Brain Stimulation of the Prelemniscal Radiations.

Martinez V, Hu SC, Foutz TJ, Ko A.

Front Surg. 2018 May 31;5:21. doi: 10.3389/fsurg.2018.00021. eCollection 2018.


Early sign of microangiopathy in systemic sclerosis: The significance of cold stress test in dynamic laser Doppler flowmetry.

Yu S, Hu SC, Yu HS, Chin YY, Cheng YC, Lee CH.

Clin Hemorheol Microcirc. 2018 Jun 5. doi: 10.3233/CH-180419. [Epub ahead of print]


[Stable hydrogen and oxygen isotope compositions in soil-plant-atmosphere continuum (SPAC) in rocky mountain area of Beijing, China].

Deng WP, Zhang J, Zhang ZJ, Hu SC, Guo JR, Liu YQ, Kong FQ, Zhang Y.

Ying Yong Sheng Tai Xue Bao. 2017 Jul 18;28(7):2171-2178. doi: 10.13287/j.1001-9332.201707.018. Chinese.


Detection of reassortant H5N6 clade highly pathogenic avian influenza virus in a black-faced spoonbill (Platalea minor) found dead, Taiwan, 2017.

Liu YP, Lee DH, Chen LH, Lin YJ, Li WC, Hu SC, Chen YP, Swayne DE, Lee MS.

Infect Genet Evol. 2018 Apr 27;62:275-278. doi: 10.1016/j.meegid.2018.04.026. [Epub ahead of print]


The Relationship between Urbanization, the Built Environment, and Physical Activity among Older Adults in Taiwan.

Huang NC, Kung SF, Hu SC.

Int J Environ Res Public Health. 2018 Apr 24;15(5). pii: E836. doi: 10.3390/ijerph15050836.


Lyssavirus in Japanese Pipistrelle, Taiwan.

Hu SC, Hsu CL, Lee MS, Tu YC, Chang JC, Wu CH, Lee SH, Ting LJ, Tsai KR, Cheng MC, Tu WJ, Hsu WC.

Emerg Infect Dis. 2018 Apr;24(4):782-785. doi: 10.3201/eid2404.171696.


Sex differences in progression to mild cognitive impairment and dementia in Parkinson's disease.

Cholerton B, Johnson CO, Fish B, Quinn JF, Chung KA, Peterson-Hiller AL, Rosenthal LS, Dawson TM, Albert MS, Hu SC, Mata IF, Leverenz JB, Poston KL, Montine TJ, Zabetian CP, Edwards KL.

Parkinsonism Relat Disord. 2018 May;50:29-36. doi: 10.1016/j.parkreldis.2018.02.007. Epub 2018 Feb 9.


Socioeconomic Inequality in One-Year Mortality of Elderly People with Hip Fracture in Taiwan.

Hsu IL, Chang CM, Yang DC, Chang YH, Li CC, Hu SC, Li CY.

Int J Environ Res Public Health. 2018 Feb 16;15(2). pii: E352. doi: 10.3390/ijerph15020352.


Population-based cohort study suggesting a significantly increased risk of developing chronic obstructive pulmonary disease in people with type 2 diabetes mellitus.

Hsu IL, Lu CL, Li CC, Tsai SH, Chen CZ, Hu SC, Li CY.

Diabetes Res Clin Pract. 2018 Apr;138:66-74. doi: 10.1016/j.diabres.2018.01.037. Epub 2018 Feb 3.


Magnolol Nanoparticles Exhibit Improved Water Solubility and Suppress TNF-α-Induced VCAM-1 Expression in Endothelial Cells.

Lee CW, Hu SC, Yen FL, Hsu LF, Lee IT, Lin ZC, Tsai MH, Huang CL, Liang CJ, Chiang YC.

J Biomed Nanotechnol. 2017 Mar;13(3):255-68.


Jaw Dystonia and Reversible Basal Ganglia Changes as an Initial Presentation of Systemic Lupus Erythematosus.

Romba M, Wang Y, Hu SC, Khot S.

Neurohospitalist. 2018 Jan;8(1):31-34. doi: 10.1177/1941874417698323. Epub 2017 Mar 10.


Inhibition of prostate cancer cell growth in vivo with short hairpin RNA targeting SATB1.

Wang Q, Hu SC, Yang CS, Chen JC, Zheng JN, Sun XQ, Wang JQ.

Oncol Lett. 2017 Dec;14(6):6592-6596. doi: 10.3892/ol.2017.7006. Epub 2017 Sep 20.


Linear IgA bullous dermatosis associated with amyotrophic lateral sclerosis.

Yang SY, Hu SC.

Clin Exp Dermatol. 2018 Jan;43(1):70-71. doi: 10.1111/ced.13274. Epub 2017 Oct 12. No abstract available.


Frailty and Its Contributory Factors in Older Adults: A Comparison of Two Asian Regions (Hong Kong and Taiwan).

Yu R, Wu WC, Leung J, Hu SC, Woo J.

Int J Environ Res Public Health. 2017 Sep 21;14(10). pii: E1096. doi: 10.3390/ijerph14101096.


Expression of redox sensing factor Nrf2 in lung macrophages and type II pneumocytes as a prognostic factor in pneumothorax recurrence.

Chiu WC, Lee YL, Chou SH, Lee YC, Su YH, Hou YA, Chiang HH, Yin HL, Hu SC, Huang MY, Huang CJ, Yuan SF.

J Thorac Dis. 2017 Aug;9(8):2498-2509. doi: 10.21037/jtd.2017.07.13.


Homocysteine and cognitive function in Parkinson's disease.

Licking N, Murchison C, Cholerton B, Zabetian CP, Hu SC, Montine TJ, Peterson-Hiller AL, Chung KA, Edwards K, Leverenz JB, Quinn JF.

Parkinsonism Relat Disord. 2017 Nov;44:1-5. doi: 10.1016/j.parkreldis.2017.08.005. Epub 2017 Aug 9.


Detecting representative data and generating synthetic samples to improve learning accuracy with imbalanced data sets.

Li DC, Hu SC, Lin LS, Yeh CW.

PLoS One. 2017 Aug 3;12(8):e0181853. doi: 10.1371/journal.pone.0181853. eCollection 2017.


A survey of the perception of well-being among emergency physicians in Taiwan.

Chen KC, Hsieh WH, Hu SC, Lai PF.

Ci Ji Yi Xue Za Zhi. 2017 Jan-Mar;29(1):30-36. doi: 10.4103/tcmj.tcmj_12_17.


Cerebrospinal Fluid Total Tau is Increased in Normal Pressure Hydrocephalus Patients who Undergo Successful Lumbar Drain Trials.

Baird G, Montine TJ, Chang JJ, Hu SC, Avellino AM.

Cureus. 2017 May 22;9(5):e1265. doi: 10.7759/cureus.1265.


Brain iron concentrations in regions of interest and relation with serum iron levels in Parkinson disease.

Costa-Mallen P, Gatenby C, Friend S, Maravilla KR, Hu SC, Cain KC, Agarwal P, Anzai Y.

J Neurol Sci. 2017 Jul 15;378:38-44. doi: 10.1016/j.jns.2017.04.035. Epub 2017 Apr 23.


Large-scale exploratory genetic analysis of cognitive impairment in Parkinson's disease.

Mata IF, Johnson CO, Leverenz JB, Weintraub D, Trojanowski JQ, Van Deerlin VM, Ritz B, Rausch R, Factor SA, Wood-Siverio C, Quinn JF, Chung KA, Peterson-Hiller AL, Espay AJ, Revilla FJ, Devoto J, Yearout D, Hu SC, Cholerton BA, Montine TJ, Edwards KL, Zabetian CP.

Neurobiol Aging. 2017 Aug;56:211.e1-211.e7. doi: 10.1016/j.neurobiolaging.2017.04.009. Epub 2017 Apr 20.


CYT-Rx20 inhibits ovarian cancer cells in vitro and in vivo through oxidative stress-induced DNA damage and cell apoptosis.

Wang YY, Chen YK, Hu SC, Hsu YL, Tsai CH, Chi TC, Huang WL, Hsieh PW, Yuan SF.

Cancer Chemother Pharmacol. 2017 Jun;79(6):1129-1140. doi: 10.1007/s00280-017-3330-9. Epub 2017 May 12.


Effects of different amounts of exercise on preventing depressive symptoms in community-dwelling older adults: a prospective cohort study in Taiwan.

Chang YC, Lu MC, Hu IH, Wu WI, Hu SC.

BMJ Open. 2017 May 2;7(4):e014256. doi: 10.1136/bmjopen-2016-014256.


Artocarpin, an isoprenyl flavonoid, induces p53-dependent or independent apoptosis via ROS-mediated MAPKs and Akt activation in non-small cell lung cancer cells.

Tsai MH, Liu JF, Chiang YC, Hu SC, Hsu LF, Lin YC, Lin ZC, Lee HC, Chen MC, Huang CL, Lee CW.

Oncotarget. 2017 Apr 25;8(17):28342-28358. doi: 10.18632/oncotarget.16058.


Parkinsonism Signs and Symptoms in Agricultural Pesticide Handlers in Washington State.

Searles Nielsen S, Hu SC, Checkoway H, Negrete M, Palmández P, Bordianu T, Racette BA, Simpson CD.

J Agromedicine. 2017;22(3):215-221. doi: 10.1080/1059924X.2017.1317684.


Aerobic-synergized exercises may improve fall-related physical fitness in older adults.

Chang YC, Wang JD, Chen HC, Hu SC.

J Sports Med Phys Fitness. 2017 May;57(5):660-669. doi: 10.23736/S0022-4707.16.05728-5.


Synthetic β-nitrostyrene derivative CYT-Rx20 as inhibitor of oral cancer cell proliferation and tumor growth through glutathione suppression and reactive oxygen species induction.

Wang YY, Chen YK, Hsu YL, Chiu WC, Tsai CH, Hu SC, Hsieh PW, Yuan SF.

Head Neck. 2017 Jun;39(6):1055-1064. doi: 10.1002/hed.24664. Epub 2017 Mar 27.


An alpha-synuclein MRM assay with diagnostic potential for Parkinson's disease and monitoring disease progression.

Yang L, Stewart T, Shi M, Pottiez G, Dator R, Wu R, Aro P, Schuster RJ, Ginghina C, Pan C, Gao Y, Qian W, Zabetian CP, Hu SC, Quinn JF, Zhang J.

Proteomics Clin Appl. 2017 Jul;11(7-8). doi: 10.1002/prca.201700045. Epub 2017 Apr 19.


Dermoscopic features of livedoid vasculopathy.

Hu SC, Chen GS, Lin CL, Cheng YC, Lin YS.

Medicine (Baltimore). 2017 Mar;96(11):e6284. doi: 10.1097/MD.0000000000006284.


Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) induced by golimumab.

Yang SY, Lan CC, Hu SC.

Int J Dermatol. 2017 May;56(5):571-572. doi: 10.1111/ijd.13565. Epub 2017 Feb 20. No abstract available.


3'-hydroxy-4'-methoxy-β-methyl-β-nitrostyrene inhibits tumorigenesis in colorectal cancer cells through ROS-mediated DNA damage and mitochondrial dysfunction.

Tsai CH, Hung AC, Chen YY, Chiu YW, Hsieh PW, Lee YC, Su YH, Chang PC, Hu SC, Yuan SF.

Oncotarget. 2017 Mar 14;8(11):18106-18117. doi: 10.18632/oncotarget.14996.


Correlation of matrix metalloproteinase-2 and -9 expression with recurrences in primary spontaneous pneumothorax patients.

Chiu WC, Lee YC, Su YH, Chai CY, Hu SC, Yuan SF, Chou SH.

J Thorac Dis. 2016 Dec;8(12):3667-3675. doi: 10.21037/jtd.2016.12.38.


3'-Hydroxy-4'-methoxy-β-methyl-β-nitrostyrene inhibits tumor growth through ROS generation and GSH depletion in lung cancer cells.

Tsai CH, Hsieh PW, Lee YC, Wang CH, Chiu WC, Lu CW, Wang YY, Hu SC, Cheng TL, Yuan SF.

Life Sci. 2017 Mar 1;172:19-26. doi: 10.1016/j.lfs.2016.12.009. Epub 2016 Dec 20.


The discovery of LRRK2 p.R1441S, a novel mutation for Parkinson's disease, adds to the complexity of a mutational hotspot.

Mata IF, Davis MY, Lopez AN, Dorschner MO, Martinez E, Yearout D, Cholerton BA, Hu SC, Edwards KL, Bird TD, Zabetian CP.

Am J Med Genet B Neuropsychiatr Genet. 2017 Jan;174(1):113. doi: 10.1002/ajmg.b.32510. Epub 2016 Dec 1. No abstract available.


Validation of Contamination Control in Rapid Transfer Port Chambers for Pharmaceutical Manufacturing Processes.

Hu SC, Shiue A, Liu HY, Chiu RB.

Int J Environ Res Public Health. 2016 Nov 12;13(11). pii: E1129.


Dermoscopic vascular network in cutaneous metastases from nasopharyngeal carcinoma.

Hu SC, Ke CK, Chen GS, Cheng ST.

J Eur Acad Dermatol Venereol. 2016 Oct;30(10):e29-e31. doi: 10.1111/jdv.13234. Epub 2015 Sep 25. No abstract available.


Association of GBA Mutations and the E326K Polymorphism With Motor and Cognitive Progression in Parkinson Disease.

Davis MY, Johnson CO, Leverenz JB, Weintraub D, Trojanowski JQ, Chen-Plotkin A, Van Deerlin VM, Quinn JF, Chung KA, Peterson-Hiller AL, Rosenthal LS, Dawson TM, Albert MS, Goldman JG, Stebbins GT, Bernard B, Wszolek ZK, Ross OA, Dickson DW, Eidelberg D, Mattis PJ, Niethammer M, Yearout D, Hu SC, Cholerton BA, Smith M, Mata IF, Montine TJ, Edwards KL, Zabetian CP.

JAMA Neurol. 2016 Oct 1;73(10):1217-1224. doi: 10.1001/jamaneurol.2016.2245.


Eupafolin nanoparticles protect HaCaT keratinocytes from particulate matter-induced inflammation and oxidative stress.

Lin ZC, Lee CW, Tsai MH, Ko HH, Fang JY, Chiang YC, Liang CJ, Hsu LF, Hu SC, Yen FL.

Int J Nanomedicine. 2016 Aug 11;11:3907-26. doi: 10.2147/IJN.S109062. eCollection 2016.


Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytes.

Hu SC, Yu HS, Yen FL, Lin CL, Chen GS, Lan CC.

Sci Rep. 2016 Aug 5;6:31119. doi: 10.1038/srep31119.


High-glucose environment disturbs the physiologic functions of keratinocytes: Focusing on diabetic wound healing.

Hu SC, Lan CE.

J Dermatol Sci. 2016 Nov;84(2):121-127. doi: 10.1016/j.jdermsci.2016.07.008. Epub 2016 Jul 16. Review.


A Population-Based Study of All-Cause Mortality and Cardiovascular Disease in Association With Prior History of Hypoglycemia Among Patients With Type 1 Diabetes.

Lu CL, Shen HN, Hu SC, Wang JD, Li CY.

Diabetes Care. 2016 Sep;39(9):1571-8. doi: 10.2337/dc15-2418. Epub 2016 Jul 6.


Smoking and haptoglobin phenotype modulate serum ferritin and haptoglobin levels in Parkinson disease.

Costa-Mallen P, Zabetian CP, Hu SC, Agarwal P, Yearout D, Checkoway H.

J Neural Transm (Vienna). 2016 Nov;123(11):1319-1330. Epub 2016 Jun 27.


Urban particulate matter down-regulates filaggrin via COX2 expression/PGE2 production leading to skin barrier dysfunction.

Lee CW, Lin ZC, Hu SC, Chiang YC, Hsu LF, Lin YC, Lee IT, Tsai MH, Fang JY.

Sci Rep. 2016 Jun 17;6:27995. doi: 10.1038/srep27995.


CNS tau efflux via exosomes is likely increased in Parkinson's disease but not in Alzheimer's disease.

Shi M, Kovac A, Korff A, Cook TJ, Ginghina C, Bullock KM, Yang L, Stewart T, Zheng D, Aro P, Atik A, Kerr KF, Zabetian CP, Peskind ER, Hu SC, Quinn JF, Galasko DR, Montine TJ, Banks WA, Zhang J.

Alzheimers Dement. 2016 Nov;12(11):1125-1131. doi: 10.1016/j.jalz.2016.04.003. Epub 2016 May 24.


The development and achievement of a healthy cities network in Taiwan: sharing leadership and partnership building.

Hu SC, Kuo HW.

Glob Health Promot. 2016 Mar;23(1 Suppl):8-17. doi: 10.1177/1757975916641566.


Eupafolin ameliorates COX-2 expression and PGE2 production in particulate pollutants-exposed human keratinocytes through ROS/MAPKs pathways.

Lee CW, Lin ZC, Hsu LF, Fang JY, Chiang YC, Tsai MH, Lee MH, Li SY, Hu SC, Lee IT, Yen FL.

J Ethnopharmacol. 2016 Aug 2;189:300-9. doi: 10.1016/j.jep.2016.05.002. Epub 2016 May 13.


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