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Items: 1 to 50 of 81

1.

Continuous Real-World Gait Monitoring in Idiopathic REM Sleep Behavior Disorder.

Del Din S, Yarnall AJ, Barber TR, Lo C, Crabbe M, Rolinski M, Baig F, Hu MT, Rochester L.

J Parkinsons Dis. 2019 Nov 16. doi: 10.3233/JPD-191773. [Epub ahead of print]

PMID:
31771071
2.

Blood biomarkers with Parkinson's disease clusters and prognosis: the oxford discovery cohort.

Lawton M, Baig F, Toulson G, Morovat A, Evetts SG, Ben-Shlomo Y, Hu MT.

Mov Disord. 2019 Nov 6. doi: 10.1002/mds.27888. [Epub ahead of print]

PMID:
31693246
3.

Genetic, Structural, and Functional Evidence Link TMEM175 to Synucleinopathies.

Krohn L, Öztürk TN, Vanderperre B, Ouled Amar Bencheikh B, Ruskey JA, Laurent SB, Spiegelman D, Postuma RB, Arnulf I, Hu MTM, Dauvilliers Y, Högl B, Stefani A, Monaca CC, Plazzi G, Antelmi E, Ferini-Strambi L, Heidbreder A, Rudakou U, Cochen De Cock V, Young P, Wolf P, Oliva P, Zhang XK, Greenbaum L, Liong C, Gagnon JF, Desautels A, Hassin-Baer S, Montplaisir JY, Dupré N, Rouleau GA, Fon EA, Trempe JF, Lamoureux G, Alcalay RN, Gan-Or Z.

Ann Neurol. 2019 Oct 28. doi: 10.1002/ana.25629. [Epub ahead of print]

PMID:
31658403
4.

From dreams to parkinsonism: tracking the journey.

Hu MTM.

Brain. 2019 Jul 1;142(7):1850-1852. doi: 10.1093/brain/awz155. No abstract available.

5.

Predicting motor, cognitive & functional impairment in Parkinson's.

Lo C, Arora S, Baig F, Lawton MA, El Mouden C, Barber TR, Ruffmann C, Klein JC, Brown P, Ben-Shlomo Y, de Vos M, Hu MT.

Ann Clin Transl Neurol. 2019 Aug;6(8):1498-1509. doi: 10.1002/acn3.50853. Epub 2019 Jul 26.

6.

Impulse control disorders in Parkinson disease and RBD: A longitudinal study of severity.

Baig F, Kelly MJ, Lawton MA, Ruffmann C, Rolinski M, Klein JC, Barber T, Lo C, Ben-Shlomo Y, Okai D, Hu MT.

Neurology. 2019 Aug 13;93(7):e675-e687. doi: 10.1212/WNL.0000000000007942. Epub 2019 Jul 16.

7.

Predictors of motor complications in early Parkinson's disease: A prospective cohort study.

Kelly MJ, Lawton MA, Baig F, Ruffmann C, Barber TR, Lo C, Klein JC, Ben-Shlomo Y, Hu MT.

Mov Disord. 2019 Aug;34(8):1174-1183. doi: 10.1002/mds.27783. Epub 2019 Jul 8.

8.

Sleep Disturbance as Potential Risk and Progression Factor for Parkinson's Disease.

Bohnen NI, Hu MTM.

J Parkinsons Dis. 2019;9(3):603-614. doi: 10.3233/JPD-191627.

9.

The Mechanisms by Which the Ketone Body D-β-Hydroxybutyrate May Improve the Multiple Cellular Pathologies of Parkinson's Disease.

Norwitz NG, Hu MT, Clarke K.

Front Nutr. 2019 May 14;6:63. doi: 10.3389/fnut.2019.00063. eCollection 2019. Review.

10.

RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes.

Booth HDE, Wessely F, Connor-Robson N, Rinaldi F, Vowles J, Browne C, Evetts SG, Hu MT, Cowley SA, Webber C, Wade-Martins R.

Neurobiol Dis. 2019 Sep;129:56-66. doi: 10.1016/j.nbd.2019.05.006. Epub 2019 May 11.

11.

Proximity extension assay testing reveals novel diagnostic biomarkers of atypical parkinsonian syndromes.

Jabbari E, Woodside J, Guo T, Magdalinou NK, Chelban V, Athauda D, Lees AJ, Foltynie T, Houlden H, Church A, Hu MT, Rowe JB, Zetterberg H, Morris HR.

J Neurol Neurosurg Psychiatry. 2019 Jul;90(7):768-773. doi: 10.1136/jnnp-2018-320151. Epub 2019 Mar 13.

12.

Detection of REM sleep behaviour disorder by automated polysomnography analysis.

Cooray N, Andreotti F, Lo C, Symmonds M, Hu MTM, De Vos M.

Clin Neurophysiol. 2019 Apr;130(4):505-514. doi: 10.1016/j.clinph.2019.01.011. Epub 2019 Feb 6.

13.

Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes.

Lang C, Campbell KR, Ryan BJ, Carling P, Attar M, Vowles J, Perestenko OV, Bowden R, Baig F, Kasten M, Hu MT, Cowley SA, Webber C, Wade-Martins R.

Cell Stem Cell. 2019 Jan 3;24(1):93-106.e6. doi: 10.1016/j.stem.2018.10.023. Epub 2018 Nov 29.

14.

Developing and validating Parkinson's disease subtypes and their motor and cognitive progression.

Lawton M, Ben-Shlomo Y, May MT, Baig F, Barber TR, Klein JC, Swallow DMA, Malek N, Grosset KA, Bajaj N, Barker RA, Williams N, Burn DJ, Foltynie T, Morris HR, Wood NW, Grosset DG, Hu MTM.

J Neurol Neurosurg Psychiatry. 2018 Dec;89(12):1279-1287. doi: 10.1136/jnnp-2018-318337. Epub 2018 Jul 25.

15.

Automating the Detection of REM Sleep Behaviour Disorder.

Cooray N, Andreotti F, Lo C, Symmonds M, Hu MTM, De Vos M.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:1460-1463. doi: 10.1109/EMBC.2018.8512539.

PMID:
30440668
16.

Multichannel Sleep Stage Classification and Transfer Learning using Convolutional Neural Networks.

Andreotti F, Phan H, Cooray N, Lo C, Hu MTM, De Vos M.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:171-174. doi: 10.1109/EMBC.2018.8512214.

PMID:
30440365
17.

The Luxembourg Parkinson's Study: A Comprehensive Approach for Stratification and Early Diagnosis.

Hipp G, Vaillant M, Diederich NJ, Roomp K, Satagopam VP, Banda P, Sandt E, Mommaerts K, Schmitz SK, Longhino L, Schweicher A, Hanff AM, Nicolai B, Kolber P, Reiter D, Pavelka L, Binck S, Pauly C, Geffers L, Betsou F, Gantenbein M, Klucken J, Gasser T, Hu MT, Balling R, Krüger R.

Front Aging Neurosci. 2018 Oct 29;10:326. doi: 10.3389/fnagi.2018.00326. eCollection 2018.

18.

Mitochondrial dysfunction and increased glycolysis in prodromal and early Parkinson's blood cells.

Smith AM, Depp C, Ryan BJ, Johnston GI, Alegre-Abarrategui J, Evetts S, Rolinski M, Baig F, Ruffmann C, Simon AK, Hu MTM, Wade-Martins R.

Mov Disord. 2018 Oct;33(10):1580-1590. doi: 10.1002/mds.104. Epub 2018 Oct 7.

19.

Smartphone motor testing to distinguish idiopathic REM sleep behavior disorder, controls, and PD.

Arora S, Baig F, Lo C, Barber TR, Lawton MA, Zhan A, Rolinski M, Ruffmann C, Klein JC, Rumbold J, Louvel A, Zaiwalla Z, Lennox G, Quinnell T, Dennis G, Wade-Martins R, Ben-Shlomo Y, Little MA, Hu MT.

Neurology. 2018 Oct 16;91(16):e1528-e1538. doi: 10.1212/WNL.0000000000006366. Epub 2018 Sep 19.

20.

Apathy in rapid eye movement sleep behaviour disorder is associated with serotonin depletion in the dorsal raphe nucleus.

Barber TR, Griffanti L, Muhammed K, Drew DS, Bradley KM, McGowan DR, Crabbe M, Lo C, Mackay CE, Husain M, Hu MT, Klein JC.

Brain. 2018 Oct 1;141(10):2848-2854. doi: 10.1093/brain/awy240.

21.

Potential Metabolomic Linkage in Blood between Parkinson's Disease and Traumatic Brain Injury.

Fiandaca MS, Gross TJ, Johnson TM, Hu MT, Evetts S, Wade-Martins R, Merchant-Borna K, Bazarian J, Cheema AK, Mapstone M, Federoff HJ.

Metabolites. 2018 Sep 7;8(3). pii: E50. doi: 10.3390/metabo8030050.

22.

Tumor suppressor LKB1 inhibits the progression of gallbladder carcinoma and predicts the prognosis of patients with this malignancy.

Hu MT, Wang JH, Yu Y, Liu C, Li B, Cheng QB, Jiang XQ.

Int J Oncol. 2018 Sep;53(3):1215-1226. doi: 10.3892/ijo.2018.4466. Epub 2018 Jul 2.

PMID:
30015925
23.

A detailed clinical study of pain in 1957 participants with early/moderate Parkinson's disease.

Silverdale MA, Kobylecki C, Kass-Iliyya L, Martinez-Martin P, Lawton M, Cotterill S, Chaudhuri KR, Morris H, Baig F, Williams N, Hubbard L, Hu MT, Grosset DG; UK Parkinson's Pain Study Collaboration.

Parkinsonism Relat Disord. 2018 Nov;56:27-32. doi: 10.1016/j.parkreldis.2018.06.001. Epub 2018 Jun 6.

24.

Full sequencing and haplotype analysis of MAPT in Parkinson's disease and rapid eye movement sleep behavior disorder.

Li J, Ruskey JA, Arnulf I, Dauvilliers Y, Hu MTM, Högl B, Leblond CS, Zhou S, Ambalavanan A, Ross JP, Bourassa CV, Spiegelman D, Laurent SB, Stefani A, Charley Monaca C, Cochen De Cock V, Boivin M, Ferini-Strambi L, Plazzi G, Antelmi E, Young P, Heidbreder A, Labbe C, Ferman TJ, Dion PA, Fan D, Desautels A, Gagnon JF, Dupré N, Fon EA, Montplaisir JY, Boeve BF, Postuma RB, Rouleau GA, Ross OA, Gan-Or Z.

Mov Disord. 2018 Jul;33(6):1016-1020. doi: 10.1002/mds.27385. Epub 2018 May 14.

PMID:
29756641
25.

Detection of alpha-synuclein conformational variants from gastro-intestinal biopsy tissue as a potential biomarker for Parkinson's disease.

Ruffmann C, Bengoa-Vergniory N, Poggiolini I, Ritchie D, Hu MT, Alegre-Abarrategui J, Parkkinen L.

Neuropathol Appl Neurobiol. 2018 Dec;44(7):722-736. doi: 10.1111/nan.12486. Epub 2018 May 8.

26.

Distinct effects of apathy and dopamine on effort-based decision-making in Parkinson's disease.

Le Heron C, Plant O, Manohar S, Ang YS, Jackson M, Lennox G, Hu MT, Husain M.

Brain. 2018 May 1;141(5):1455-1469. doi: 10.1093/brain/awy110.

27.

LRRK2 protective haplotype and full sequencing study in REM sleep behavior disorder.

Ouled Amar Bencheikh B, Ruskey JA, Arnulf I, Dauvilliers Y, Monaca CC, De Cock VC, Gagnon JF, Spiegelman D, Hu MTM, Högl B, Stefani A, Ferini-Strambi L, Plazzi G, Antelmi E, Young P, Heidbreder A, Mollenhauer B, Sixel-Döring F, Trenkwalder C, Oertel W, Montplaisir JY, Postuma RB, Rouleau GA, Gan-Or Z.

Parkinsonism Relat Disord. 2018 Jul;52:98-101. doi: 10.1016/j.parkreldis.2018.03.019. Epub 2018 Mar 21.

PMID:
29576439
28.

Exploring variability in basal ganglia connectivity with functional MRI in healthy aging.

Griffanti L, Stratmann P, Rolinski M, Filippini N, Zsoldos E, Mahmood A, Zamboni G, Douaud G, Klein JC, Kivimäki M, Singh-Manoux A, Hu MT, Ebmeier KP, Mackay CE.

Brain Imaging Behav. 2018 Dec;12(6):1822-1827. doi: 10.1007/s11682-018-9824-1.

29.

Cortical structural involvement and cognitive dysfunction in early Parkinson's disease.

Klein JC, Rolinski M, Griffanti L, Szewczyk-Krolikowski K, Baig F, Ruffmann C, Groves AR, Menke RAL, Hu MT, Mackay C.

NMR Biomed. 2018 Apr;31(4):e3900. doi: 10.1002/nbm.3900. Epub 2018 Feb 13.

PMID:
29436039
30.

Cerebrospinal fluid macrophage biomarkers in amyotrophic lateral sclerosis.

Thompson AG, Gray E, Thézénas ML, Charles PD, Evetts S, Hu MT, Talbot K, Fischer R, Kessler BM, Turner MR.

Ann Neurol. 2018 Feb;83(2):258-268. doi: 10.1002/ana.25143. Epub 2018 Feb 9.

PMID:
29331073
31.

Apathy in rapid eye movement sleep behaviour disorder is common and under-recognized.

Barber TR, Muhammed K, Drew D, Lawton M, Crabbe M, Rolinski M, Quinnell T, Zaiwalla Z, Ben-Shlomo Y, Husain M, Hu MTM.

Eur J Neurol. 2018 Mar;25(3):469-e32. doi: 10.1111/ene.13515. Epub 2017 Dec 14.

32.

Considerations in the Use of MDS Research Criteria for Prodromal Parkinson's in Rapid Eye Movement Sleep Behaviour Disorder and Population Cohorts.

Barber TR, Lawton M, Ben-Shlomo Y, Hu MTM.

Sleep. 2017 Oct 1;40(10). doi: 10.1093/sleep/zsx169. No abstract available.

PMID:
29029243
33.

Neuroimaging in pre-motor Parkinson's disease.

Barber TR, Klein JC, Mackay CE, Hu MTM.

Neuroimage Clin. 2017 Apr 21;15:215-227. doi: 10.1016/j.nicl.2017.04.011. eCollection 2017. Review.

34.

Prodromal Parkinsonism and Neurodegenerative Risk Stratification in REM Sleep Behavior Disorder.

Barber TR, Lawton M, Rolinski M, Evetts S, Baig F, Ruffmann C, Gornall A, Klein JC, Lo C, Dennis G, Bandmann O, Quinnell T, Zaiwalla Z, Ben-Shlomo Y, Hu MTM.

Sleep. 2017 Aug 1;40(8). doi: 10.1093/sleep/zsx071.

35.

Personality and addictive behaviours in early Parkinson's disease and REM sleep behaviour disorder.

Baig F, Lawton MA, Rolinski M, Ruffmann C, Klein JC, Nithi K, Okai D, Ben-Shlomo Y, Hu MT.

Parkinsonism Relat Disord. 2017 Apr;37:72-78. doi: 10.1016/j.parkreldis.2017.01.017. Epub 2017 Feb 1.

36.

[Protective effects of Curcumin analogue L6H4 on kidney from type 2 diabetic rats].

Liu X, Ma J, Hu MT, Dong XD, Xiang LT, Gu QR, Du ZY, Chen SM, Chen GR.

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2017 Jan 8;33(1):11-15. doi: 10.12047/j.cjap.5448.2017.003. Chinese.

PMID:
29926600
37.

The dementia-associated APOE ε4 allele is not associated with rapid eye movement sleep behavior disorder.

Gan-Or Z, Montplaisir JY, Ross JP, Poirier J, Warby SC, Arnulf I, Strong S, Dauvilliers Y, Leblond CS, Hu MTM, Högl B, Stefani A, Monaca CC, De Cock VC, Boivin M, Ferini-Strambi L, Plazzi G, Antelmi E, Young P, Heidbreder A, Barber TR, Evetts SG, Rolinski M, Dion PA, Desautels A, Gagnon JF, Dupré N, Postuma RB, Rouleau GA.

Neurobiol Aging. 2017 Jan;49:218.e13-218.e15. doi: 10.1016/j.neurobiolaging.2016.10.002. Epub 2016 Oct 13.

PMID:
27814994
38.

Alpha-synuclein RT-QuIC in the CSF of patients with alpha-synucleinopathies.

Fairfoul G, McGuire LI, Pal S, Ironside JW, Neumann J, Christie S, Joachim C, Esiri M, Evetts SG, Rolinski M, Baig F, Ruffmann C, Wade-Martins R, Hu MT, Parkkinen L, Green AJ.

Ann Clin Transl Neurol. 2016 Aug 28;3(10):812-818. eCollection 2016 Oct.

39.

Equating scores of the University of Pennsylvania Smell Identification Test and Sniffin' Sticks test in patients with Parkinson's disease.

Lawton M, Hu MT, Baig F, Ruffmann C, Barron E, Swallow DM, Malek N, Grosset KA, Bajaj N, Barker RA, Williams N, Burn DJ, Foltynie T, Morris HR, Wood NW, May MT, Grosset DG, Ben-Shlomo Y.

Parkinsonism Relat Disord. 2016 Dec;33:96-101. doi: 10.1016/j.parkreldis.2016.09.023. Epub 2016 Sep 25.

40.

Statins are underused in recent-onset Parkinson's disease with increased vascular risk: findings from the UK Tracking Parkinson's and Oxford Parkinson's Disease Centre (OPDC) discovery cohorts.

Swallow DM, Lawton MA, Grosset KA, Malek N, Klein J, Baig F, Ruffmann C, Bajaj NP, Barker RA, Ben-Shlomo Y, Burn DJ, Foltynie T, Morris HR, Williams N, Wood NW, Hu MT, Grosset DG.

J Neurol Neurosurg Psychiatry. 2016 Nov;87(11):1183-1190. doi: 10.1136/jnnp-2016-313642. Epub 2016 Sep 26.

41.

Kinematic Analyses of the Thumb during Simulated Posteroanterior Glide Mobilization.

Hu MT, Hsu AT, Su FC.

PLoS One. 2016 Sep 1;11(9):e0161624. doi: 10.1371/journal.pone.0161624. eCollection 2016.

42.

Aiming for Study Comparability in Parkinson's Disease: Proposal for a Modular Set of Biomarker Assessments to be Used in Longitudinal Studies.

Lerche S, Heinzel S, Alves GW, Barone P, Behnke S, Ben-Shlomo Y, Berendse H, Bloem BR, Burn D, Dodel R, Grosset DG, Hipp G, Hu MT, Kasten M, Krüger R, Liepelt-Scarfone I, Maetzler W, Moccia M, Mollenhauer B, Oertel W, Roeben B, Walter U, Wirdefeldt K, Berg D.

Front Aging Neurosci. 2016 May 27;8:121. doi: 10.3389/fnagi.2016.00121. eCollection 2016. No abstract available.

43.

Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson's disease.

Rolinski M, Griffanti L, Piccini P, Roussakis AA, Szewczyk-Krolikowski K, Menke RA, Quinnell T, Zaiwalla Z, Klein JC, Mackay CE, Hu MT.

Brain. 2016 Aug;139(Pt 8):2224-34. doi: 10.1093/brain/aww124. Epub 2016 Jun 12.

44.

Acute variegate porphyria presenting with reversible cerebral vasoconstriction.

Webb AJ, Ingale H, Irani SR, Hu MT.

Clin Neurol Neurosurg. 2016 Jul;146:102-4. doi: 10.1016/j.clineuro.2016.04.018. Epub 2016 May 6. No abstract available.

PMID:
27186968
45.

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.

Fernandes HJ, Hartfield EM, Christian HC, Emmanoulidou E, Zheng Y, Booth H, Bogetofte H, Lang C, Ryan BJ, Sardi SP, Badger J, Vowles J, Evetts S, Tofaris GK, Vekrellis K, Talbot K, Hu MT, James W, Cowley SA, Wade-Martins R.

Stem Cell Reports. 2016 Mar 8;6(3):342-56. doi: 10.1016/j.stemcr.2016.01.013. Epub 2016 Feb 18.

46.

Validation of conversion between mini-mental state examination and montreal cognitive assessment.

Lawton M, Kasten M, May MT, Mollenhauer B, Schaumburg M, Liepelt-Scarfone I, Maetzler W, Vollstedt EJ, Hu MT, Berg D, Ben-Shlomo Y.

Mov Disord. 2016 Apr;31(4):593-6. doi: 10.1002/mds.26498. Epub 2016 Feb 10.

47.

Visual short-term memory deficits in REM sleep behaviour disorder mirror those in Parkinson's disease.

Rolinski M, Zokaei N, Baig F, Giehl K, Quinnell T, Zaiwalla Z, Mackay CE, Husain M, Hu MT.

Brain. 2016 Jan;139(Pt 1):47-53. doi: 10.1093/brain/awv334. Epub 2015 Nov 18.

48.

Precompetitive Data Sharing as a Catalyst to Address Unmet Needs in Parkinson's Disease.

Stephenson D, Hu MT, Romero K, Breen K, Burn D, Ben-Shlomo Y, Bhattaram A, Isaac M, Venuto C, Kubota K, Little MA, Friend S, Lovestone S, Morris HR, Grosset D, Sutherland M, Gallacher J, Williams-Gray C, Bain LJ, Avilés E, Marek K, Toga AW, Stark Y, Forrest Gordon M, Ford S.

J Parkinsons Dis. 2015;5(3):581-94. doi: 10.3233/JPD-150570.

49.

Parkinson's Disease Subtypes in the Oxford Parkinson Disease Centre (OPDC) Discovery Cohort.

Lawton M, Baig F, Rolinski M, Ruffman C, Nithi K, May MT, Ben-Shlomo Y, Hu MT.

J Parkinsons Dis. 2015;5(2):269-79. doi: 10.3233/JPD-140523.

50.

Challenges in the reproducibility of clinical studies with resting state fMRI: An example in early Parkinson's disease.

Griffanti L, Rolinski M, Szewczyk-Krolikowski K, Menke RA, Filippini N, Zamboni G, Jenkinson M, Hu MTM, Mackay CE.

Neuroimage. 2016 Jan 1;124(Pt A):704-713. doi: 10.1016/j.neuroimage.2015.09.021. Epub 2015 Sep 16.

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