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Interspecies Inhibition of Porphyromonas gingivalis by Yogurt-Derived Lactobacillus delbrueckii Requires Active Pyruvate Oxidase.

Cornacchione LP, Klein BA, Duncan MJ, Hu LT.

Appl Environ Microbiol. 2019 Aug 29;85(18). pii: e01271-19. doi: 10.1128/AEM.01271-19. Print 2019 Sep 15.


Effect of colloids on non-Fickian transport of strontium in sediments elucidated by continuous-time random walk analysis.

Liu DX, Zuo R, Jivkov AP, Wang JS, Hu LT, Huang LX.

Environ Pollut. 2019 Sep;252(Pt B):1491-1499. doi: 10.1016/j.envpol.2019.06.064. Epub 2019 Jun 20.


Expression of macrophage migration inhibitory factor in Aspergillus fumigatus keratitis.

Xu Q, Hu LT, Wang Q, Lin J, Jiang N, Li C, Zhao GQ.

Int J Ophthalmol. 2019 May 18;12(5):711-716. doi: 10.18240/ijo.2019.05.03. eCollection 2019.


Genome-wide screen identifies novel genes required for Borrelia burgdorferi survival in its Ixodes tick vector.

Phelan JP, Kern A, Ramsey ME, Lundt ME, Sharma B, Lin T, Gao L, Norris SJ, Hyde JA, Skare JT, Hu LT.

PLoS Pathog. 2019 May 14;15(5):e1007644. doi: 10.1371/journal.ppat.1007644. eCollection 2019 May.


Identifying Vancomycin as an Effective Antibiotic for Killing Borrelia burgdorferi.

Wu X, Sharma B, Niles S, O'Connor K, Schilling R, Matluck N, D'Onofrio A, Hu LT, Lewis K.

Antimicrob Agents Chemother. 2018 Oct 24;62(11). pii: e01201-18. doi: 10.1128/AAC.01201-18. Print 2018 Nov.


Mincle in the innate immune response of mice fungal keratitis.

Yu GR, Lin J, Zhang J, Che CY, Peng XD, Li C, Hu LT, Zhu GQ, He K, Zhao GQ.

Int J Ophthalmol. 2018 Apr 18;11(4):539-547. doi: 10.18240/ijo.2018.04.01. eCollection 2018.


Meta-analysis of the efficacy and safety of combined surgery in the management of eyes with coexisting cataract and open angle glaucoma.

Jiang N, Zhao GQ, Lin J, Hu LT, Che CY, Wang Q, Xu Q, Li C, Zhang J.

Int J Ophthalmol. 2018 Feb 18;11(2):279-286. doi: 10.18240/ijo.2018.02.17. eCollection 2018.


Magnetic Isolation of Phagosomes Containing Toll-Like Receptor Ligands.

Petnicki-Ocwieja T, Hu LT.

Methods Mol Biol. 2018;1690:329-336. doi: 10.1007/978-1-4939-7383-5_25.


Correction: Lyme borreliosis.

Steere AC, Franc S, Wormser GP, Hu LT, Branda JA, Hovius JWR, Li X, Mead PS.

Nat Rev Dis Primers. 2017 Aug 3;3:17062. doi: 10.1038/nrdp.2017.62.


Phagocytic Receptors Activate Syk and Src Signaling during Borrelia burgdorferi Phagocytosis.

Killpack TL, Ballesteros M, Bunnell SC, Bedugnis A, Kobzik L, Hu LT, Petnicki-Ocwieja T.

Infect Immun. 2017 Sep 20;85(10). pii: e00004-17. doi: 10.1128/IAI.00004-17. Print 2017 Oct.


The expressions of metadherin and LEF-1 in mucosa-associated lymphoid tissue lymphoma of ocular adnexal.

Qi D, Lin H, Gao Y, Lin J, Hu LT, Zhao GQ.

Int J Ophthalmol. 2017 May 18;10(5):705-710. doi: 10.18240/ijo.2017.05.07. eCollection 2017.


Using Tn-seq To Identify Pigmentation-Related Genes of Porphyromonas gingivalis: Characterization of the Role of a Putative Glycosyltransferase.

Klein BA, Cornacchione LP, Collins M, Malamy MH, Duncan MJ, Hu LT.

J Bacteriol. 2017 Jun 27;199(14). pii: e00832-16. doi: 10.1128/JB.00832-16. Print 2017 Jul 15.


HMGCS2 promotes autophagic degradation of the amyloid-β precursor protein through ketone body-mediated mechanisms.

Hu LT, Zhu BL, Lai YJ, Long Y, Zha JS, Hu XT, Zhang JH, Chen GJ.

Biochem Biophys Res Commun. 2017 Apr 29;486(2):492-498. doi: 10.1016/j.bbrc.2017.03.069. Epub 2017 Mar 18.


A high-throughput genetic screen identifies previously uncharacterized Borrelia burgdorferi genes important for resistance against reactive oxygen and nitrogen species.

Ramsey ME, Hyde JA, Medina-Perez DN, Lin T, Gao L, Lundt ME, Li X, Norris SJ, Skare JT, Hu LT.

PLoS Pathog. 2017 Feb 17;13(2):e1006225. doi: 10.1371/journal.ppat.1006225. eCollection 2017 Feb.


Lyme borreliosis.

Steere AC, Strle F, Wormser GP, Hu LT, Branda JA, Hovius JW, Li X, Mead PS.

Nat Rev Dis Primers. 2016 Dec 15;2:16090. doi: 10.1038/nrdp.2016.90. Review. Erratum in: Nat Rev Dis Primers. 2017 Aug 03;3:17062.


High-performance SERS substrate based on hybrid structure of graphene oxide/AgNPs/Cu film@pyramid Si.

Li Z, Xu SC, Zhang C, Liu XY, Gao SS, Hu LT, Guo J, Ma Y, Jiang SZ, Si HP.

Sci Rep. 2016 Dec 7;6:38539. doi: 10.1038/srep38539.


The role of Dectin-1/Raf-1 signal cascade in innate immune of human corneal epithelial cells against Aspergillus fumigatus infection.

Zhao GQ, Lin J, Hu LT, Yin XN, Wang Q, Xu Q, Li H.

Int J Ophthalmol. 2016 Oct 18;9(10):1371-1375. eCollection 2016.


Lyme Disease.

Hu LT.

Ann Intern Med. 2016 Nov 1;165(9):677. doi: 10.7326/L16-0409. No abstract available.


The role of LOX-1 on innate immunity against Aspergillus keratitis in mice.

He K, Yue LH, Zhao GQ, Li C, Lin J, Jiang N, Wang Q, Xu Q, Peng XD, Hu LT, Zhang J.

Int J Ophthalmol. 2016 Sep 18;9(9):1245-50. doi: 10.18240/ijo.2016.09.01. eCollection 2016.


[Kinetics and Mechanistic Investigation of the Photocatalytic Degradation of Clothianidin].

Hu Q, Yang H, Shi N, Hu LT, Yi B.

Huan Jing Ke Xue. 2016 Sep 8;37(9):3524-3531. doi: 10.13227/j.hjkx.2016.09.034. Chinese.


Live-vaccinia virus encapsulation in pH-sensitive polymer increases safety of a reservoir-targeted Lyme disease vaccine by targeting gastrointestinal release.

Kern A, Zhou CW, Jia F, Xu Q, Hu LT.

Vaccine. 2016 Aug 31;34(38):4507-4513. doi: 10.1016/j.vaccine.2016.07.059. Epub 2016 Aug 5.


Human β-NGF gene transferred to cat corneal endothelial cells.

Luo WJ, Liu M, Zhao GQ, Wang CF, Hu LT, Liu XP.

Int J Ophthalmol. 2016 Jul 18;9(7):937-42. doi: 10.18240/ijo.2016.07.01. eCollection 2016.


[Photocatalytic Degradation Kinetics and Mechanism of Monoazo Dye Acid Yellow 17 by UV/TiO2 in Aqueous Solution].

Yang H, Wei HQ, Hu LT, Hu Q, Yang LP, Liu HJ, Yi X, Yi B.

Huan Jing Ke Xue. 2016 Aug 8;37(8):3086-3093. doi: 10.13277/j.hjkx.2016.08.033. Chinese.


Global Tn-seq analysis of carbohydrate utilization and vertebrate infectivity of Borrelia burgdorferi.

Troy EB, Lin T, Gao L, Lazinski DW, Lundt M, Camilli A, Norris SJ, Hu LT.

Mol Microbiol. 2016 Sep;101(6):1003-23. doi: 10.1111/mmi.13437. Epub 2016 Jul 15.


Expression of indoleamine 2,3-dioxygenase in a murine model of Aspergillus fumigatus keratitis.

Jiang N, Zhao GQ, Lin J, Hu LT, Che CY, Li C, Wang Q, Xu Q, Zhang J, Peng XD.

Int J Ophthalmol. 2016 Apr 18;9(4):491-6. doi: 10.18240/ijo.2016.04.03. eCollection 2016.


Lyme Disease.

Hu LT.

Ann Intern Med. 2016 May 3;164(9):ITC65-ITC80. doi: 10.7326/AITC201605030. Review.


Diagnosis, Treatment, and Prevention of Lyme Disease, Human Granulocytic Anaplasmosis, and Babesiosis: A Review.

Sanchez E, Vannier E, Wormser GP, Hu LT.

JAMA. 2016 Apr 26;315(16):1767-77. doi: 10.1001/jama.2016.2884. Review.


Co-regulation of Dectin-1 and TLR2 in inflammatory response of human corneal epithelial cells induced by Aspergillus fumigates.

Zhao GQ, Qiu XY, Lin J, Li Q, Hu LT, Wang Q, Li H.

Int J Ophthalmol. 2016 Feb 18;9(2):185-90. doi: 10.18240/ijo.2016.02.01. eCollection 2016.


Protein tyrosine phosphatase 1B regulates migration of ARPE-19 cells through EGFR/ERK signaling pathway.

Du ZD, Hu LT, Zhao GQ, Wang Q, Xu Q, Jiang N, Lin J.

Int J Ophthalmol. 2015 Oct 18;8(5):891-7. doi: 10.3980/j.issn.2222-3959.2015.05.07. eCollection 2015.


Expression of vitamin D receptor and cathelicidin in human corneal epithelium cells during fusarium solani infection.

Cong L, Xia YP, Zhao GQ, Lin J, Xu Q, Hu LT, Qu JQ, Peng XD.

Int J Ophthalmol. 2015 Oct 18;8(5):866-71. doi: 10.3980/j.issn.2222-3959.2015.05.03. eCollection 2015.


Patient with erythematous lesion on thenar eminence.

Guo H, Zheng S, Hu LT, Lan XO, Gao XH, Chen HD, Li JH.

Int J Dermatol. 2016 Jun;55(6):615-6. doi: 10.1111/ijd.12983. Epub 2015 Oct 16. No abstract available.


Identification and characterization of a minisatellite contained within a novel miniature inverted-repeat transposable element (MITE) of Porphyromonas gingivalis.

Klein BA, Chen T, Scott JC, Koenigsberg AL, Duncan MJ, Hu LT.

Mob DNA. 2015 Oct 6;6:18. doi: 10.1186/s13100-015-0049-1. eCollection 2015.


Adaptor Protein-3-Mediated Trafficking of TLR2 Ligands Controls Specificity of Inflammatory Responses but Not Adaptor Complex Assembly.

Petnicki-Ocwieja T, Kern A, Killpack TL, Bunnell SC, Hu LT.

J Immunol. 2015 Nov 1;195(9):4331-40. doi: 10.4049/jimmunol.1501268. Epub 2015 Sep 30.


Dectin-1 agonist curdlan modulates innate immunity to Aspergillus fumigatus in human corneal epithelial cells.

Zhu CC, Zhao GQ, Lin J, Hu LT, Xu Q, Peng XD, Wang X, Qiu S.

Int J Ophthalmol. 2015 Aug 18;8(4):690-6. doi: 10.3980/j.issn.2222-3959.2015.04.09. eCollection 2015.


CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 24-2015. A 28-Year-Old Pregnant Woman with Fever, Chills, Headache, and Fatigue.

Hu LT, Tsibris AM, Branda JA.

N Engl J Med. 2015 Jul 30;373(5):468-75. doi: 10.1056/NEJMcpc1501763. No abstract available.


Natamycin in the treatment of fungal keratitis: a systematic review and Meta-analysis.

Qiu S, Zhao GQ, Lin J, Wang X, Hu LT, Du ZD, Wang Q, Zhu CC.

Int J Ophthalmol. 2015 Jun 18;8(3):597-602. doi: 10.3980/j.issn.2222-3959.2015.03.29. eCollection 2015.


Multiple targets for multiple sclerosis.

Hu LT, Sun F, Chen GJ.

Genes Dis. 2015 Jun 16;2(3):222-223. doi: 10.1016/j.gendis.2015.06.001. eCollection 2015 Sep. No abstract available.


Local hyperthermia combined with topical imiquimod cleared extensive and recalcitrant common warts on the scalp.

Hu LT, Qi RQ, Huo W, Ren Y, Zheng S, Hong Y, Guo H, Chen HD, Gao XH.

Eur J Dermatol. 2015 Jul-Aug;25(4):366-7. doi: 10.1684/ejd.2015.2585. No abstract available.


Borrelia burgdorferi, the Causative Agent of Lyme Disease, Forms Drug-Tolerant Persister Cells.

Sharma B, Brown AV, Matluck NE, Hu LT, Lewis K.

Antimicrob Agents Chemother. 2015 Aug;59(8):4616-24. doi: 10.1128/AAC.00864-15. Epub 2015 May 26.


Protein tyrosine phosphatase 1B regulates the activity of retinal pigment epithelial cells.

Du ZD, Hu LT, Zhao GQ, Li Y, Ma ZZ.

Mol Vis. 2015 May 1;21:523-31. eCollection 2015.


A Randomized, Double-Blind, Placebo-Controlled Trial of Citicoline for Cocaine Dependence in Bipolar I Disorder.

Brown ES, Todd JP, Hu LT, Schmitz JM, Carmody TJ, Nakamura A, Sunderajan P, Rush AJ, Adinoff B, Bret ME, Holmes T, Lo A.

Am J Psychiatry. 2015 Oct;172(10):1014-21. doi: 10.1176/appi.ajp.2015.14070857. Epub 2015 May 22.


TREM-1 expression in rat corneal epithelium with Aspergillus fumigatus infection.

Hu LT, Du ZD, Zhao GQ, Qiu S, Jiang N, Lin J, Wang Q, Xu Q.

Int J Ophthalmol. 2015 Apr 18;8(2):222-7. doi: 10.3980/j.issn.2222-3959.2015.02.02. eCollection 2015.


Early expression of mannose-binding lectin 2 during Aspergillus fumigatus infection in human corneal epithelial cells.

Che CY, Zhang JF, Lee JE, Lin J, Hu LT, Jiang N, Wang Q, Xu Q, Zhao GQ.

Int J Ophthalmol. 2015 Feb 18;8(1):35-8. doi: 10.3980/j.issn.2222-3959.2015.01.06. eCollection 2015.


Is there a place for xenodiagnosis in the clinic?

Telford SR 3rd, Hu LT, Marques A.

Expert Rev Anti Infect Ther. 2014 Nov;12(11):1307-10. doi: 10.1586/14787210.2014.966084.


Role of TREM-1 in response to Aspergillus fumigatus infection in corneal epithelial cells.

Hu LT, Du ZD, Zhao GQ, Jiang N, Lin J, Wang Q, Xu Q, Cong L, Qiu S.

Int Immunopharmacol. 2014 Nov;23(1):288-93. doi: 10.1016/j.intimp.2014.09.011. Epub 2014 Sep 19.


Transposon mutagenesis as an approach to improved understanding of Borrelia pathogenesis and biology.

Lin T, Troy EB, Hu LT, Gao L, Norris SJ.

Front Cell Infect Microbiol. 2014 May 20;4:63. doi: 10.3389/fcimb.2014.00063. eCollection 2014. Review.


Xenodiagnosis to detect Borrelia burgdorferi infection: a first-in-human study.

Marques A, Telford SR 3rd, Turk SP, Chung E, Williams C, Dardick K, Krause PJ, Brandeburg C, Crowder CD, Carolan HE, Eshoo MW, Shaw PA, Hu LT.

Clin Infect Dis. 2014 Apr;58(7):937-45. doi: 10.1093/cid/cit939. Epub 2014 Feb 11.


Understanding barriers to Borrelia burgdorferi dissemination during infection using massively parallel sequencing.

Troy EB, Lin T, Gao L, Lazinski DW, Camilli A, Norris SJ, Hu LT.

Infect Immun. 2013 Jul;81(7):2347-57. doi: 10.1128/IAI.00266-13. Epub 2013 Apr 22.

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