Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 44

1.

Intergenic splicing between four adjacent UGT genes (2B15, 2B29P2, 2B17, 2B29P1) gives rise to variant UGT proteins that inhibit glucuronidation via protein-protein interactions.

Hu DG, Hulin JA, Wijayakumara DD, McKinnon RA, Mackenzie PI, Meech R.

Mol Pharmacol. 2018 Jun 29. pii: mol.118.111773. doi: 10.1124/mol.118.111773. [Epub ahead of print]

2.

Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element.

Mubarokah N, Hulin JA, Mackenzie PI, McKinnon RA, Haines AZ, Hu DG, Meech R.

Mol Pharmacol. 2018 May;93(5):541-552. doi: 10.1124/mol.117.110619. Epub 2018 Mar 8.

PMID:
29519853
3.

The Glucose Sensor MdHXK1 Phosphorylates a Tonoplast Na+/H+ Exchanger to Improve Salt Tolerance.

Sun MH, Ma QJ, Hu DG, Zhu XP, You CX, Shu HR, Hao YJ.

Plant Physiol. 2018 Apr;176(4):2977-2990. doi: 10.1104/pp.17.01472. Epub 2018 Feb 12.

4.

Regulation of UDP-Glucuronosyltransferase 2B15 by miR-331-5p in Prostate Cancer Cells Involves Canonical and Noncanonical Target Sites.

Wijayakumara DD, Mackenzie PI, McKinnon RA, Hu DG, Meech R.

J Pharmacol Exp Ther. 2018 Apr;365(1):48-59. doi: 10.1124/jpet.117.245936. Epub 2018 Jan 24.

PMID:
29367276
5.

Ectopic expression of the apple nucleus-encoded thylakoid protein MdY3IP1 triggers early-flowering and enhanced salt-tolerance in Arabidopsis thaliana.

Yu JQ, Wang JH, Sun CH, Zhang QY, Hu DG, Hao YJ.

BMC Plant Biol. 2018 Jan 20;18(1):18. doi: 10.1186/s12870-018-1232-6.

6.

Chrysanthemum MADS-box transcription factor CmANR1 modulates lateral root development via homo-/heterodimerization to influence auxin accumulation in Arabidopsis.

Sun CH, Yu JQ, Wen LZ, Guo YH, Sun X, Hao YJ, Hu DG, Zheng CS.

Plant Sci. 2018 Jan;266:27-36. doi: 10.1016/j.plantsci.2017.09.017. Epub 2017 Sep 23.

PMID:
29241564
7.

[Evaluate the Efficacy of Electroacupuncture Therapy on Abdominal Fat in Obese Women by Using Magnetic Resonance Imaging].

Lei H, Chen X, Hu DG, Chen YT, Feng LC, Chen ZY, Li F.

Zhen Ci Yan Jiu. 2016 Oct 25;41(5):451-6. Chinese.

PMID:
29071948
8.

MiR-193b regulates breast cancer cell migration and vasculogenic mimicry by targeting dimethylarginine dimethylaminohydrolase 1.

Hulin JA, Tommasi S, Elliot D, Hu DG, Lewis BC, Mangoni AA.

Sci Rep. 2017 Oct 25;7(1):13996. doi: 10.1038/s41598-017-14454-1.

9.

Transcription Factor AREB2 Is Involved in Soluble Sugar Accumulation by Activating Sugar Transporter and Amylase Genes.

Ma QJ, Sun MH, Lu J, Liu YJ, Hu DG, Hao YJ.

Plant Physiol. 2017 Aug;174(4):2348-2362. doi: 10.1104/pp.17.00502. Epub 2017 Jun 9.

PMID:
28600345
10.

MdSnRK1.1 interacts with MdJAZ18 to regulate sucrose-induced anthocyanin and proanthocyanidin accumulation in apple.

Liu XJ, An XH, Liu X, Hu DG, Wang XF, You CX, Hao YJ.

J Exp Bot. 2017 May 17;68(11):2977-2990. doi: 10.1093/jxb/erx150.

PMID:
28549152
11.

The R2R3-MYB transcription factor MdMYB73 is involved in malate accumulation and vacuolar acidification in apple.

Hu DG, Li YY, Zhang QY, Li M, Sun CH, Yu JQ, Hao YJ.

Plant J. 2017 Aug;91(3):443-454. doi: 10.1111/tpj.13579. Epub 2017 Jun 6.

PMID:
28423209
12.

Nitrate: A Crucial Signal during Lateral Roots Development.

Sun CH, Yu JQ, Hu DG.

Front Plant Sci. 2017 Apr 4;8:485. doi: 10.3389/fpls.2017.00485. eCollection 2017. Review.

13.

Exemestane and Its Active Metabolite 17-Hydroexemestane Induce UDP-Glucuronosyltransferase (UGT) 2B17 Expression in Breast Cancer Cells.

Chanawong A, Mackenzie PI, McKinnon RA, Hu DG, Meech R.

J Pharmacol Exp Ther. 2017 Jun;361(3):482-491. doi: 10.1124/jpet.117.240317. Epub 2017 Apr 12.

14.

Regulation of UDP-Glucuronosyltransferases UGT2B4 and UGT2B7 by MicroRNAs in Liver Cancer Cells.

Wijayakumara DD, Mackenzie PI, McKinnon RA, Hu DG, Meech R.

J Pharmacol Exp Ther. 2017 Jun;361(3):386-397. doi: 10.1124/jpet.116.239707. Epub 2017 Apr 7.

15.

Novel Nine-Exon AR Transcripts (Exon 1/Exon 1b/Exons 2-8) in Normal and Cancerous Breast and Prostate Cells.

Hu DG, McKinnon RA, Hulin JA, Mackenzie PI, Meech R.

Int J Mol Sci. 2016 Dec 27;18(1). pii: E40. doi: 10.3390/ijms18010040.

16.

Molecular cloning and functional characterization of the apple sucrose transporter gene MdSUT2.

Ma QJ, Sun MH, Liu YJ, Lu J, Hu DG, Hao YJ.

Plant Physiol Biochem. 2016 Dec;109:442-451. doi: 10.1016/j.plaphy.2016.10.026. Epub 2016 Oct 27.

PMID:
27816825
17.

Glucose Sensor MdHXK1 Phosphorylates and Stabilizes MdbHLH3 to Promote Anthocyanin Biosynthesis in Apple.

Hu DG, Sun CH, Zhang QY, An JP, You CX, Hao YJ.

PLoS Genet. 2016 Aug 25;12(8):e1006273. doi: 10.1371/journal.pgen.1006273. eCollection 2016 Aug.

18.

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

Hu DG, Selth LA, Tarulli GA, Meech R, Wijayakumara D, Chanawong A, Russell R, Caldas C, Robinson JL, Carroll JS, Tilley WD, Mackenzie PI, Hickey TE.

Cancer Res. 2016 Oct 1;76(19):5881-5893. Epub 2016 Aug 5.

19.

MdSOS2L1 forms a complex with MdMYB1 to control vacuolar pH by transcriptionally regulating MdVHA-B1 in apples.

Sun CH, Zhang QY, Sun MH, Hu DG.

Plant Signal Behav. 2016;11(3):e1146846. doi: 10.1080/15592324.2016.1146846.

20.

Genetic polymorphisms of human UDP-glucuronosyltransferase (UGT) genes and cancer risk.

Hu DG, Mackenzie PI, McKinnon RA, Meech R.

Drug Metab Rev. 2016;48(1):47-69. doi: 10.3109/03602532.2015.1131292. Epub 2016 Feb 1. Review.

PMID:
26828111
21.

MdSOS2L1 phosphorylates MdVHA-B1 to modulate malate accumulation in response to salinity in apple.

Hu DG, Sun CH, Sun MH, Hao YJ.

Plant Cell Rep. 2016 Mar;35(3):705-18. doi: 10.1007/s00299-015-1914-6. Epub 2015 Dec 19.

PMID:
26687966
22.

MdMYB1 Regulates Anthocyanin and Malate Accumulation by Directly Facilitating Their Transport into Vacuoles in Apples.

Hu DG, Sun CH, Ma QJ, You CX, Cheng L, Hao YJ.

Plant Physiol. 2016 Mar;170(3):1315-30. doi: 10.1104/pp.15.01333. Epub 2015 Dec 4.

23.

Expression of androgen receptor splice variants in clinical breast cancers.

Hickey TE, Irvine CM, Dvinge H, Tarulli GA, Hanson AR, Ryan NK, Pickering MA, Birrell SN, Hu DG, Mackenzie PI, Russell R, Caldas C, Raj GV, Dehm SM, Plymate SR, Bradley RK, Tilley WD, Selth LA.

Oncotarget. 2015 Dec 29;6(42):44728-44. doi: 10.18632/oncotarget.6296.

24.

Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines.

Wijayakumara DD, Hu DG, Meech R, McKinnon RA, Mackenzie PI.

J Pharmacol Exp Ther. 2015 Sep;354(3):417-25. doi: 10.1124/jpet.115.226118. Epub 2015 Jul 10.

25.

Overexpression of MdSOS2L1, a CIPK protein kinase, increases the antioxidant metabolites to enhance salt tolerance in apple and tomato.

Hu DG, Ma QJ, Sun CH, Sun MH, You CX, Hao YJ.

Physiol Plant. 2016 Feb;156(2):201-214. doi: 10.1111/ppl.12354. Epub 2015 Jul 22.

PMID:
26096498
26.

Induction of UDP-glucuronosyltransferase 2B15 gene expression by the major active metabolites of tamoxifen, 4-hydroxytamoxifen and endoxifen, in breast cancer cells.

Chanawong A, Hu DG, Meech R, Mackenzie PI, McKinnon RA.

Drug Metab Dispos. 2015 Jun;43(6):889-97. doi: 10.1124/dmd.114.062935. Epub 2015 Mar 20.

27.

Induction of human UDP-Glucuronosyltransferase 2B7 gene expression by cytotoxic anticancer drugs in liver cancer HepG2 cells.

Hu DG, Mackenzie PI, Lu L, Meech R, McKinnon RA.

Drug Metab Dispos. 2015 May;43(5):660-8. doi: 10.1124/dmd.114.062380. Epub 2015 Feb 23.

28.

A novel function for UDP glycosyltransferase 8: galactosidation of bile acids.

Meech R, Mubarokah N, Shivasami A, Rogers A, Nair PC, Hu DG, McKinnon RA, Mackenzie PI.

Mol Pharmacol. 2015;87(3):442-50. doi: 10.1124/mol.114.093823. Epub 2014 Dec 17.

29.

Transcriptional regulation of human UDP-glucuronosyltransferase genes.

Hu DG, Meech R, McKinnon RA, Mackenzie PI.

Drug Metab Rev. 2014 Nov;46(4):421-58. doi: 10.3109/03602532.2014.973037. Epub 2014 Oct 22. Review.

PMID:
25336387
30.

Epirubicin upregulates UDP glucuronosyltransferase 2B7 expression in liver cancer cells via the p53 pathway.

Hu DG, Rogers A, Mackenzie PI.

Mol Pharmacol. 2014 Jun;85(6):887-97. doi: 10.1124/mol.114.091603. Epub 2014 Mar 28.

31.

Identification of androgen receptor splice variant transcripts in breast cancer cell lines and human tissues.

Hu DG, Hickey TE, Irvine C, Wijayakumara DD, Lu L, Tilley WD, Selth LA, Mackenzie PI.

Horm Cancer. 2014 Apr;5(2):61-71. doi: 10.1007/s12672-014-0171-4. Epub 2014 Feb 26.

PMID:
24570075
32.

Polymorphisms and haplotypes of the UDP-glucuronosyltransferase 2B7 gene promoter.

Hu DG, Meech R, Lu L, McKinnon RA, Mackenzie PI.

Drug Metab Dispos. 2014 May;42(5):854-62. doi: 10.1124/dmd.113.056630. Epub 2014 Feb 21.

33.

MdVHA-A encodes an apple subunit A of vacuolar H(+)-ATPase and enhances drought tolerance in transgenic tobacco seedlings.

Dong QL, Wang CR, Liu DD, Hu DG, Fang MJ, You CX, Yao YX, Hao YJ.

J Plant Physiol. 2013 Apr 15;170(6):601-9. doi: 10.1016/j.jplph.2012.12.014. Epub 2013 Feb 9.

PMID:
23399407
34.

Molecular cloning and functional characterization of MdSOS2 reveals its involvement in salt tolerance in apple callus and Arabidopsis.

Hu DG, Li M, Luo H, Dong QL, Yao YX, You CX, Hao YJ.

Plant Cell Rep. 2012 Apr;31(4):713-22. doi: 10.1007/s00299-011-1189-5. Epub 2011 Nov 23.

PMID:
22108717
35.

A new hybrid fractal algorithm for predicting thermophilic nucleotide sequences.

Lu JL, Hu XH, Hu DG.

J Theor Biol. 2012 Jan 21;293:74-81. doi: 10.1016/j.jtbi.2011.09.028. Epub 2011 Oct 10.

PMID:
22001320
36.

MdVHP1 encodes an apple vacuolar H(+)-PPase and enhances stress tolerance in transgenic apple callus and tomato.

Dong QL, Liu DD, An XH, Hu DG, Yao YX, Hao YJ.

J Plant Physiol. 2011 Nov 15;168(17):2124-33. doi: 10.1016/j.jplph.2011.07.001. Epub 2011 Aug 15.

PMID:
21840622
37.

Forkhead box protein A1 regulates UDP-glucuronosyltransferase 2B15 gene transcription in LNCaP prostate cancer cells.

Hu DG, Mackenzie PI.

Drug Metab Dispos. 2010 Dec;38(12):2105-9. doi: 10.1124/dmd.110.035436. Epub 2010 Aug 24.

38.

A novel polymorphism in a forkhead box A1 (FOXA1) binding site of the human UDP glucuronosyltransferase 2B17 gene modulates promoter activity and is associated with altered levels of circulating androstane-3α,17β-diol glucuronide.

Hu DG, Gardner-Stephen D, Severi G, Gregory PA, Treloar J, Giles GG, English DR, Hopper JL, Tilley WD, Mackenzie PI.

Mol Pharmacol. 2010 Oct;78(4):714-22. doi: 10.1124/mol.110.065953. Epub 2010 Jul 13.

39.

The regulation of UDP-glucuronosyltransferase genes by tissue-specific and ligand-activated transcription factors.

Mackenzie PI, Hu DG, Gardner-Stephen DA.

Drug Metab Rev. 2010 Feb;42(1):99-109. doi: 10.3109/03602530903209544.

PMID:
20070244
41.
42.

Singleton births after routine preimplantation genetic diagnosis using exclusion testing (D4S43 and D4S126) for Huntington's disease.

Jasper MJ, Hu DG, Liebelt J, Sherrin D, Watson R, Tremellen KP, Hussey ND.

Fertil Steril. 2006 Mar;85(3):597-602.

PMID:
16500325
43.

Prenatal molecular diagnosis of Duchenne and Becker muscular dystrophy.

Li Q, Li SY, Hu DG, Sun XF, Chen DJ, Zhang C, Jiang WY.

Beijing Da Xue Xue Bao Yi Xue Ban. 2006 Feb 18;38(1):53-6.

44.

Aneuploidy detection in single cells using DNA array-based comparative genomic hybridization.

Hu DG, Webb G, Hussey N.

Mol Hum Reprod. 2004 Apr;10(4):283-9. Epub 2004 Jan 29.

PMID:
14985479

Supplemental Content

Support Center