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Baicalin modulates apoptosis via RAGE, MAPK, and AP-1 in vascular endothelial cells during Haemophilus parasuis invasion.

Fu S, Zhao W, Xiong C, Guo L, Guo J, Qiu Y, Hu CA, Ye C, Liu Y, Wu Z, Hou Y.

Innate Immun. 2019 Oct;25(7):420-432. doi: 10.1177/1753425919856078. Epub 2019 Jul 4. No abstract available.


Effect of Baicalin-Aluminum Complexes on Fecal Microbiome in Piglets.

Fu S, Zhuang F, Guo L, Qiu Y, Xiong J, Ye C, Liu Y, Wu Z, Hou Y, Hu CA.

Int J Mol Sci. 2019 May 14;20(10). pii: E2390. doi: 10.3390/ijms20102390.


Effects of Baicalin on piglet monocytes involving PKC-MAPK signaling pathways induced by Haemophilus parasuis.

Ye C, Li R, Xu L, Qiu Y, Fu S, Liu Y, Wu Z, Hou Y, Hu CA.

BMC Vet Res. 2019 Mar 25;15(1):98. doi: 10.1186/s12917-019-1840-x.


Lentinan modulates intestinal microbiota and enhances barrier integrity in a piglet model challenged with lipopolysaccharide.

Wang X, Wang W, Wang L, Yu C, Zhang G, Zhu H, Wang C, Zhao S, Hu CA, Liu Y.

Food Funct. 2019 Jan 22;10(1):479-489. doi: 10.1039/c8fo02438c.


A Small Molecule BH3-mimetic Suppresses Cigarette Smoke-Induced Mucous Expression in Airway Epithelial Cells.

Hussain SS, George S, Singh S, Jayant R, Hu CA, Sopori M, Chand HS.

Sci Rep. 2018 Sep 14;8(1):13796. doi: 10.1038/s41598-018-32114-w.


Transcriptional Profiling of Host Cell Responses to Virulent Haemophilus parasuis: New Insights into Pathogenesis.

Fu S, Guo J, Li R, Qiu Y, Ye C, Liu Y, Wu Z, Guo L, Hou Y, Hu CA.

Int J Mol Sci. 2018 Apr 29;19(5). pii: E1320. doi: 10.3390/ijms19051320.


Baicalin Inhibits Haemophilus Parasuis-Induced High-Mobility Group Box 1 Release during Inflammation.

Fu S, Liu H, Chen X, Qiu Y, Ye C, Liu Y, Wu Z, Guo L, Hou Y, Hu CA.

Int J Mol Sci. 2018 Apr 27;19(5). pii: E1307. doi: 10.3390/ijms19051307.


Correction: Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage.

De Leo A, Chen HS, Hu CA, Lieberman PM.

PLoS Pathog. 2018 Apr 25;14(4):e1007027. doi: 10.1371/journal.ppat.1007027. eCollection 2018 Apr.


DNA Methylation and the Potential Role of Methyl-Containing Nutrients in Cardiovascular Diseases.

Liu G, Bin P, Wang T, Ren W, Zhong J, Liang J, Hu CA, Zeng Z, Yin Y.

Oxid Med Cell Longev. 2017;2017:1670815. doi: 10.1155/2017/1670815. Epub 2017 Nov 16. Review.


Baicalin modulates NF-κB and NLRP3 inflammasome signaling in porcine aortic vascular endothelial cells Infected by Haemophilus parasuis Causing Glässer's disease.

Fu S, Liu H, Xu L, Qiu Y, Liu Y, Wu Z, Ye C, Hou Y, Hu CA.

Sci Rep. 2018 Jan 16;8(1):807. doi: 10.1038/s41598-018-19293-2.


Intestinal enteroendocrine L cells in amino acid sensing and diseases.

Ding X, Hu CA, Huang P, Li Y, He S, Yang H, Li J, Xie H, Yin Y.

Front Biosci (Landmark Ed). 2018 Mar 1;23:1740-1753. Review.


Metabolism, Nutrition, and Redox Signaling of Hydroxyproline.

Wu Z, Hou Y, Dai Z, Hu CA, Wu G.

Antioxid Redox Signal. 2019 Feb 1;30(4):674-682. doi: 10.1089/ars.2017.7338. Epub 2017 Oct 30.


The role of methionine on metabolism, oxidative stress, and diseases.

Martínez Y, Li X, Liu G, Bin P, Yan W, Más D, Valdivié M, Hu CA, Ren W, Yin Y.

Amino Acids. 2017 Dec;49(12):2091-2098. doi: 10.1007/s00726-017-2494-2. Epub 2017 Sep 19. Review.


Therapeutic Potential of Amino Acids in Inflammatory Bowel Disease.

Liu Y, Wang X, Hu CA.

Nutrients. 2017 Aug 23;9(9). pii: E920. doi: 10.3390/nu9090920. Review.


Asparagine preserves intestinal barrier function from LPS-induced injury and regulates CRF/CRFR signaling pathway.

Zhu H, Pi D, Leng W, Wang X, Hu CA, Hou Y, Xiong J, Wang C, Qin Q, Liu Y.

Innate Immun. 2017 Aug;23(6):546-556. doi: 10.1177/1753425917721631. Epub 2017 Jul 21.


Roles of amino acids in preventing and treating intestinal diseases: recent studies with pig models.

Liu Y, Wang X, Hou Y, Yin Y, Qiu Y, Wu G, Hu CA.

Amino Acids. 2017 Aug;49(8):1277-1291. doi: 10.1007/s00726-017-2450-1. Epub 2017 Jun 14. Review.


Molecular cloning, characterization and expression analysis of Frizzled 6 in the small intestine of pigs (Sus scrofa).

Zou L, Wang X, Jiang L, Wang S, Xiong X, Yang H, Gao W, Gong M, Hu CA, Yin Y.

PLoS One. 2017 Jun 14;12(6):e0179421. doi: 10.1371/journal.pone.0179421. eCollection 2017.


Methionine restriction on oxidative stress and immune response in dss-induced colitis mice.

Liu G, Yu L, Fang J, Hu CA, Yin J, Ni H, Ren W, Duraipandiyan V, Chen S, Al-Dhabi NA, Yin Y.

Oncotarget. 2017 Jul 4;8(27):44511-44520. doi: 10.18632/oncotarget.17812.


Short-term supplementation of isocaloric meals with L-tryptophan affects pig growth.

Liu HN, Hu CA, Bai MM, Liu G, Tossou MCB, Xu K, Li FN, Liao P, Kong XF, Wu X, Yin YL.

Amino Acids. 2017 Dec;49(12):2009-2014. doi: 10.1007/s00726-017-2440-3. Epub 2017 May 24.


Human interstitial cellular model in therapeutics of heart valve calcification.

He C, Tang H, Mei Z, Li N, Zeng Z, Darko KO, Yin Y, Hu CA, Yang X.

Amino Acids. 2017 Dec;49(12):1981-1997. doi: 10.1007/s00726-017-2432-3. Epub 2017 May 23. Review.


Functions of pregnane X receptor in self-detoxification.

He L, Zhou X, Huang N, Li H, Li T, Yao K, Tian Y, Hu CA, Yin Y.

Amino Acids. 2017 Dec;49(12):1999-2007. doi: 10.1007/s00726-017-2435-0. Epub 2017 May 22. Review.


Zebrafish as a model to evaluate peptide-related cancer therapies.

Shull AY, Hu CA, Teng Y.

Amino Acids. 2017 Dec;49(12):1907-1913. doi: 10.1007/s00726-017-2388-3. Epub 2017 Mar 18. Review.


L-Glutamine and L-arginine protect against enterotoxigenic Escherichia coli infection via intestinal innate immunity in mice.

Liu G, Ren W, Fang J, Hu CA, Guan G, Al-Dhabi NA, Yin J, Duraipandiyan V, Chen S, Peng Y, Yin Y.

Amino Acids. 2017 Dec;49(12):1945-1954. doi: 10.1007/s00726-017-2410-9. Epub 2017 Mar 15.


N-Acetylcysteine improves intestinal function in lipopolysaccharides-challenged piglets through multiple signaling pathways.

Yi D, Hou Y, Xiao H, Wang L, Zhang Y, Chen H, Wu T, Ding B, Hu CA, Wu G.

Amino Acids. 2017 Dec;49(12):1915-1929. doi: 10.1007/s00726-017-2389-2. Epub 2017 Mar 7.


N-Acetylcysteine supplementation alleviates intestinal injury in piglets infected by porcine epidemic diarrhea virus.

Wang L, Zhou J, Hou Y, Yi D, Ding B, Xie J, Zhang Y, Chen H, Wu T, Zhao D, Hu CA, Wu G.

Amino Acids. 2017 Dec;49(12):1931-1943. doi: 10.1007/s00726-017-2397-2. Epub 2017 Mar 3.


Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.

Beckerman P, Bi-Karchin J, Park AS, Qiu C, Dummer PD, Soomro I, Boustany-Kari CM, Pullen SS, Miner JH, Hu CA, Rohacs T, Inoue K, Ishibe S, Saleem MA, Palmer MB, Cuervo AM, Kopp JB, Susztak K.

Nat Med. 2017 Apr;23(4):429-438. doi: 10.1038/nm.4287. Epub 2017 Feb 20.


Evaluation of recombinant protein superoxide dismutase of Haemophilus parasuis strain SH0165 as vaccine candidate in a mouse model.

Guo L, Xu L, Wu T, Fu S, Qiu Y, Hu CA, Ren X, Liu R, Ye M.

Can J Microbiol. 2017 Apr;63(4):312-320. doi: 10.1139/cjm-2016-0671. Epub 2016 Dec 22.


FGF19/FGFR4 signaling contributes to the resistance of hepatocellular carcinoma to sorafenib.

Gao L, Wang X, Tang Y, Huang S, Hu CA, Teng Y.

J Exp Clin Cancer Res. 2017 Jan 9;36(1):8. doi: 10.1186/s13046-016-0478-9.


Aspartate inhibits LPS-induced MAFbx and MuRF1 expression in skeletal muscle in weaned pigs by regulating Akt, AMPKα and FOXO1.

Liu Y, Wang X, Leng W, Pi D, Tu Z, Zhu H, Shi H, Li S, Hou Y, Hu CA.

Innate Immun. 2017 Jan;23(1):34-43. doi: 10.1177/1753425916673443. Epub 2016 Oct 22.


Myokines and adipokines: Involvement in the crosstalk between skeletal muscle and adipose tissue.

Li F, Li Y, Duan Y, Hu CA, Tang Y, Yin Y.

Cytokine Growth Factor Rev. 2017 Feb;33:73-82. doi: 10.1016/j.cytogfr.2016.10.003. Epub 2016 Oct 13. Review.


β-Conglycinin enhances autophagy in porcine enterocytes.

Yi D, Hou Y, Mei H, Wang L, Hu CA, Wu G.

Amino Acids. 2017 Jan;49(1):203-207. doi: 10.1007/s00726-016-2352-7. Epub 2016 Oct 19.


Variants in autophagy-related genes and clinical characteristics in melanoma: a population-based study.

White KA, Luo L, Thompson TA, Torres S, Hu CA, Thomas NE, Lilyquist J, Anton-Culver H, Gruber SB, From L, Busam KJ, Orlow I, Kanetsky PA, Marrett LD, Gallagher RP, Sacchetto L, Rosso S, Dwyer T, Cust AE, Begg CB, Berwick M; GEM Study Group.

Cancer Med. 2016 Nov;5(11):3336-3345. doi: 10.1002/cam4.929. Epub 2016 Oct 17.


Asparagine improves intestinal integrity, inhibits TLR4 and NOD signaling, and differently regulates p38 and ERK1/2 signaling in weanling piglets after LPS challenge.

Chen S, Liu Y, Wang X, Wang H, Li S, Shi H, Zhu H, Zhang J, Pi D, Hu CA, Lin X, Odle J.

Innate Immun. 2016 Nov;22(8):577-587. doi: 10.1177/1753425916664124. Epub 2016 Sep 21.


Baicalin suppresses NLRP3 inflammasome and nuclear factor-kappa B (NF-κB) signaling during Haemophilus parasuis infection.

Fu S, Xu L, Li S, Qiu Y, Liu Y, Wu Z, Ye C, Hou Y, Hu CA.

Vet Res. 2016 Aug 8;47(1):80. doi: 10.1186/s13567-016-0359-4.


Glycine enhances muscle protein mass associated with maintaining Akt-mTOR-FOXO1 signaling and suppressing TLR4 and NOD2 signaling in piglets challenged with LPS.

Liu Y, Wang X, Wu H, Chen S, Zhu H, Zhang J, Hou Y, Hu CA, Zhang G.

Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R365-73. doi: 10.1152/ajpregu.00043.2016. Epub 2016 May 25.


Erratum to: Amino acids and autophagy: their crosstalk, interplay and interlock.

Hu CA, Wu Z, Wang J.

Amino Acids. 2015 Dec;47(12):2673. doi: 10.1007/s00726-015-2116-9. No abstract available.


Autophagy protects intestinal epithelial cells against deoxynivalenol toxicity by alleviating oxidative stress via IKK signaling pathway.

Tang Y, Li J, Li F, Hu CA, Liao P, Tan K, Tan B, Xiong X, Liu G, Li T, Yin Y.

Free Radic Biol Med. 2015 Dec;89:944-51. doi: 10.1016/j.freeradbiomed.2015.09.012. Epub 2015 Oct 9.


N-acetylcysteine stimulates protein synthesis in enterocytes independently of glutathione synthesis.

Yi D, Hou Y, Wang L, Long M, Hu S, Mei H, Yan L, Hu CA, Wu G.

Amino Acids. 2016 Feb;48(2):523-33. doi: 10.1007/s00726-015-2105-z. Epub 2015 Oct 3.


How complicated can it be? The link between APOL1 risk variants and lipoprotein heterogeneity in kidney and cardiovascular diseases.

Hu CA, Ray PE.

Nephrol Dial Transplant. 2016 Apr;31(4):509-11. doi: 10.1093/ndt/gfv357. Epub 2015 Oct 3. No abstract available.


Signaling Pathways Related to Protein Synthesis and Amino Acid Concentration in Pig Skeletal Muscles Depend on the Dietary Protein Level, Genotype and Developmental Stages.

Liu Y, Li F, Kong X, Tan B, Li Y, Duan Y, Blachier F, Hu CA, Yin Y.

PLoS One. 2015 Sep 22;10(9):e0138277. doi: 10.1371/journal.pone.0138277. eCollection 2015.


Amino acids and autophagy: their crosstalk, interplay and interlock.

Hu CA, Wu Z, Wang J.

Amino Acids. 2015 Oct;47(10):2035-6. doi: 10.1007/s00726-015-2098-7. Epub 2015 Sep 15. No abstract available. Erratum in: Amino Acids. 2015 Dec;47(12):2673.


Intimacy and a deadly feud: the interplay of autophagy and apoptosis mediated by amino acids.

Wu Z, Hu CA, Wu G, Zhaorigetu S, Chand H, Sun K, Ji Y, Wang B, Dai Z, Walton B, Miao Y, Hou Y.

Amino Acids. 2015 Oct;47(10):2089-99. doi: 10.1007/s00726-015-2084-0. Epub 2015 Sep 9. Review.


Autophagy and tight junction proteins in the intestine and intestinal diseases.

Hu CA, Hou Y, Yi D, Qiu Y, Wu G, Kong X, Yin Y.

Anim Nutr. 2015 Sep;1(3):123-127. doi: 10.1016/j.aninu.2015.08.014. Epub 2015 Sep 1. Review.


Iron-based superparamagnetic nanoparticle contrast agents for MRI of infection and inflammation.

Neuwelt A, Sidhu N, Hu CA, Mlady G, Eberhardt SC, Sillerud LO.

AJR Am J Roentgenol. 2015 Mar;204(3):W302-13. doi: 10.2214/AJR.14.12733. Review.


Autophagy enhances intestinal epithelial tight junction barrier function by targeting claudin-2 protein degradation.

Nighot PK, Hu CA, Ma TY.

J Biol Chem. 2015 Mar 13;290(11):7234-46. doi: 10.1074/jbc.M114.597492. Epub 2015 Jan 23.


Tc-99m-labeled RGD-conjugated alpha-melanocyte stimulating hormone hybrid peptides with reduced renal uptake.

Yang J, Hu CA, Miao Y.

Amino Acids. 2015 Apr;47(4):813-23. doi: 10.1007/s00726-014-1911-z. Epub 2015 Jan 4.


Bioactive dietary peptides and amino acids in inflammatory bowel disease.

Zhang H, Hu CA, Kovacs-Nolan J, Mine Y.

Amino Acids. 2015 Oct;47(10):2127-41. doi: 10.1007/s00726-014-1886-9. Epub 2014 Dec 14. Review.


Amino acid deprivation disrupts barrier function and induces protective autophagy in intestinal porcine epithelial cells.

Yang Y, Li W, Sun Y, Han F, Hu CA, Wu Z.

Amino Acids. 2015 Oct;47(10):2177-84. doi: 10.1007/s00726-014-1844-6. Epub 2014 Oct 7.


Amentoflavone inhibits angiogenesis of endothelial cells and stimulates apoptosis in hypertrophic scar fibroblasts.

Zhang J, Liu Z, Cao W, Chen L, Xiong X, Qin S, Zhang Z, Li X, Hu CA.

Burns. 2014 Aug;40(5):922-9. doi: 10.1016/j.burns.2013.10.012. Epub 2013 Nov 23.


Deacetylation of p53 induces autophagy by suppressing Bmf expression.

Contreras AU, Mebratu Y, Delgado M, Montano G, Hu CA, Ryter SW, Choi AM, Lin Y, Xiang J, Chand H, Tesfaigzi Y.

J Cell Biol. 2013 Apr 29;201(3):427-37. doi: 10.1083/jcb.201205064.

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