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Items: 1 to 50 of 95

1.

Design, synthesis and evaluation of antiproliferative activity of fluorinated betulinic acid.

Li J, Chang LC, Hsieh KY, Hsu PL, Capuzzi SJ, Zhang YC, Li KP, Morris-Natschke SL, Goto M, Lee KH.

Bioorg Med Chem. 2019 Jul 1;27(13):2871-2882. doi: 10.1016/j.bmc.2019.05.016. Epub 2019 May 11.

PMID:
31126820
2.

Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization.

Zhang Y, Goto M, Oda A, Hsu PL, Guo LL, Fu YH, Morris-Natschke SL, Hamel E, Lee KH, Hao XJ.

Molecules. 2019 Mar 31;24(7). pii: E1256. doi: 10.3390/molecules24071256.

3.

Shear-Induced CCN1 Promotes Atheroprone Endothelial Phenotypes and Atherosclerosis.

Hsu PL, Chen JS, Wang CY, Wu HL, Mo FE.

Circulation. 2019 Jun 18;139(25):2877-2891. doi: 10.1161/CIRCULATIONAHA.118.033895. Epub 2019 Mar 28.

PMID:
30917686
4.

Targeting Anthrax Toxin Receptor 2 Ameliorates Endometriosis Progression.

Lin SC, Lee HC, Hsu CT, Huang YH, Li WN, Hsu PL, Wu MH, Tsai SJ.

Theranostics. 2019 Jan 21;9(3):620-632. doi: 10.7150/thno.30655. eCollection 2019.

5.

TYRO3: A potential therapeutic target in cancer.

Hsu PL, Jou J, Tsai SJ.

Exp Biol Med (Maywood). 2019 Feb;244(2):83-99. doi: 10.1177/1535370219828195. Epub 2019 Feb 2.

PMID:
30714403
6.

On the representation of effective stress for computing hemolysis.

Wu P, Gao Q, Hsu PL.

Biomech Model Mechanobiol. 2019 Jun;18(3):665-679. doi: 10.1007/s10237-018-01108-y. Epub 2019 Jan 2.

PMID:
30604300
7.

On the Accuracy of Hemolysis Models in Couette-Type Blood Shearing Devices.

Wu P, Boehning F, Groß-Hardt S, Hsu PL.

Artif Organs. 2018 Oct;42(10):E290-E303. doi: 10.1111/aor.13292.

PMID:
30375677
8.

Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module.

Hsu PL, Li H, Lau HT, Leonen C, Dhall A, Ong SE, Chatterjee C, Zheng N.

Cell. 2018 Aug 23;174(5):1106-1116.e9. doi: 10.1016/j.cell.2018.06.038. Epub 2018 Aug 9.

9.

Ganoderma Triterpenoids Exert Antiatherogenic Effects in Mice by Alleviating Disturbed Flow-Induced Oxidative Stress and Inflammation.

Hsu PL, Lin YC, Ni H, Mo FE.

Oxid Med Cell Longev. 2018 Apr 11;2018:3491703. doi: 10.1155/2018/3491703. eCollection 2018.

10.

Development of novel amino-quinoline-5,8-dione derivatives as NAD(P)H:quinone oxidoreductase 1 (NQO1) inhibitors with potent antiproliferative activities.

Ling Y, Yang QX, Teng YN, Chen S, Gao WJ, Guo J, Hsu PL, Liu Y, Morris-Natschke SL, Hung CC, Lee KH.

Eur J Med Chem. 2018 Jun 25;154:199-209. doi: 10.1016/j.ejmech.2018.05.025. Epub 2018 May 18.

11.

Mechanism of action of cytotoxic compounds from the seeds of Euphorbia lathyris.

Teng YN, Wang Y, Hsu PL, Xin G, Zhang Y, Morris-Natschke SL, Goto M, Lee KH.

Phytomedicine. 2018 Mar 1;41:62-66. doi: 10.1016/j.phymed.2018.02.001. Epub 2018 Feb 2.

12.

Design, Synthesis and Structure-Activity Relationships of (±)-Isochaihulactone Derivatives.

Zhao Y, Liu PY, Hsieh KY, Hsu PL, Goto M, Morris-Natschke SL, Harn HJ, Lee KH.

Medchemcomm. 2017;8(11):2040-2049. doi: 10.1039/C7MD00310B. Epub 2017 Oct 12.

13.

Reconstitution of the CstF complex unveils a regulatory role for CstF-50 in recognition of 3'-end processing signals.

Yang W, Hsu PL, Yang F, Song JE, Varani G.

Nucleic Acids Res. 2018 Jan 25;46(2):493-503. doi: 10.1093/nar/gkx1177.

14.

Total Synthesis of (+)-Medicarpin.

Yang X, Zhao Y, Hsieh MT, Xin G, Wu RT, Hsu PL, Horng LY, Sung HC, Cheng CH, Lee KH.

J Nat Prod. 2017 Dec 22;80(12):3284-3288. doi: 10.1021/acs.jnatprod.7b00741. Epub 2017 Nov 22.

PMID:
29164880
15.

Systematic Design of a Magnetically Levitated Brushless DC Motor for a Reversible Rotary Intra-Aortic Blood Pump.

Wang Y, Logan TG, Smith PA, Hsu PL, Cohn WE, Xu L, McMahon RA.

Artif Organs. 2017 Oct;41(10):923-933. doi: 10.1111/aor.12965. Epub 2017 Sep 20.

PMID:
28929512
16.

Design, semisynthesis and potent cytotoxic activity of novel 10-fluorocamptothecin derivatives.

Yang CJ, Song ZL, Goto M, Hsu PL, Zhang XS, Yang QR, Liu YQ, Wang MJ, Morris-Natschke SL, Shang XF, Lee KH.

Bioorg Med Chem Lett. 2017 Oct 15;27(20):4694-4697. doi: 10.1016/j.bmcl.2017.09.012. Epub 2017 Sep 8.

17.

In Vivo and Mechanistic Studies on Antitumor Lead 7-Methoxy-4-(2-methylquinazolin-4-yl)-3,4-dihydroquinoxalin-2(1H)-one and Its Modification as a Novel Class of Tubulin-Binding Tumor-Vascular Disrupting Agents.

Cui MT, Jiang L, Goto M, Hsu PL, Li L, Zhang Q, Wei L, Yuan SJ, Hamel E, Morris-Natschke SL, Lee KH, Xie L.

J Med Chem. 2017 Jul 13;60(13):5586-5598. doi: 10.1021/acs.jmedchem.7b00273. Epub 2017 Jun 27.

18.

Hybrid Extracorporeal Membrane Oxygenation Using Avalon Elite Double Lumen Cannula Ensures Adequate Heart/Brain Oxygen Supply.

Zhao J, Wang D, Ballard-Croft C, Wang J, Hsu PL, Bacchetta M, Zwischenberger JB.

Ann Thorac Surg. 2017 Sep;104(3):847-853. doi: 10.1016/j.athoracsur.2017.01.119. Epub 2017 May 9.

PMID:
28499654
19.

A mock heart engineered with helical aramid fibers for in vitro cardiovascular device testing.

Jansen-Park SH, Hsu PL, Müller I, Steinseifer U, Abel D, Autschbach R, Rossaint R, Schmitz-Rode T.

Biomed Tech (Berl). 2017 Apr 1;62(2):139-148. doi: 10.1515/bmt-2016-0106.

PMID:
28375841
20.

A Numerical Simulation Comparing a Cavopulmonary Assist Device and VA ECMO for Failing Fontan Support.

Hsu PL, Wang D, Ballard-Croft C, Xiao D, Zwischenberger JB.

ASAIO J. 2017 Sep/Oct;63(5):604-612. doi: 10.1097/MAT.0000000000000560.

PMID:
28319522
21.

In Vitro Evaluation of the Dual-Diffuser Design for a Reversible Rotary Intra-Aortic Ventricular Assist Device.

Wang Y, Smith PA, Timms DL, Hsu PL, McMahon RA.

Artif Organs. 2016 Sep;40(9):884-93. doi: 10.1111/aor.12746. Epub 2016 Jun 30.

PMID:
27357189
22.

Matricellular protein CCN1 mediates doxorubicin-induced cardiomyopathy in mice.

Hsu PL, Mo FE.

Oncotarget. 2016 Jun 14;7(24):36698-36710. doi: 10.18632/oncotarget.9162.

23.

In-Series Versus In-Parallel Mechanical Circulatory Support for the Right Heart: A Simulation Study.

Hsu PL, McIntyre M, Boehning F, Dang W, Parker J, Autschbach R, Schmitz-Rode T, Steinseifer U.

Artif Organs. 2016 Jun;40(6):561-7. doi: 10.1111/aor.12601. Epub 2015 Oct 29.

PMID:
26511211
24.

Activating mitochondrial function and haemoglobin expression with EH-201, an inducer of erythropoietin in neuronal cells, reverses memory impairment.

Horng LY, Hsu PL, Chen LW, Tseng WZ, Hsu KT, Wu CL, Wu RT.

Br J Pharmacol. 2015 Oct;172(19):4741-56. doi: 10.1111/bph.13248. Epub 2015 Aug 10.

25.

Hydraulic and hemodynamic performance of a minimally invasive intra-arterial right ventricular assist device.

Hsu PL, Graefe R, Boehning F, Wu C, Parker J, Autschbach R, Schmitz-Rode T, Steinseifer U.

Int J Artif Organs. 2014 Sep;37(9):697-705. doi: 10.5301/ijao.5000351. Epub 2014 Sep 27.

PMID:
25262631
26.

Internal ribosome entry site of bFGF is the target of thalidomide for IMiDs development in multiple myeloma.

Lien IC, Horng LY, Hsu PL, Wu CL, Sung HC, Wu RT.

Genes Cancer. 2014 Mar;5(3-4):127-41.

27.

Rtr1 is a dual specificity phosphatase that dephosphorylates Tyr1 and Ser5 on the RNA polymerase II CTD.

Hsu PL, Yang F, Smith-Kinnaman W, Yang W, Song JE, Mosley AL, Varani G.

J Mol Biol. 2014 Aug 12;426(16):2970-81. doi: 10.1016/j.jmb.2014.06.010. Epub 2014 Jun 18.

28.

Selective reduction of afterload in right heart assist therapy: a mock loop study†.

Hsu PL, Hatam N, Unterkofler J, Goetzenich A, McIntyre M, Wong KC, Egger C, Schmitz-Rode T, Autschbach R, Steinseifer U.

Interact Cardiovasc Thorac Surg. 2014 Jul;19(1):76-81. doi: 10.1093/icvts/ivu067. Epub 2014 Mar 26.

PMID:
24670773
29.

Design method of a foldable ventricular assist device for minimally invasive implantation.

Hsu PL, Wang Y, Amaral F, Parker J, Schmitz-Rode T, Autschbach R, Steinseifer U.

Artif Organs. 2014 Apr;38(4):298-308. doi: 10.1111/aor.12145. Epub 2013 Aug 22.

PMID:
24033499
30.

Experimental and analytical performance evaluation of short circular hydrodynamic journal bearings used in rotary blood pumps.

Boehning F, Timms D, Hsu PL, Schmitz-Rode T, Steinseifer U.

Artif Organs. 2013 Oct;37(10):913-20. doi: 10.1111/aor.12076. Epub 2013 May 2.

PMID:
23634963
31.

The triterpenoids of Ganoderma tsugae prevent stress-induced myocardial injury in mice.

Kuok QY, Yeh CY, Su BC, Hsu PL, Ni H, Liu MY, Mo FE.

Mol Nutr Food Res. 2013 Oct;57(10):1892-6. doi: 10.1002/mnfr.201200704. Epub 2013 Apr 23.

PMID:
23610080
32.

Activation of mitochondrial function and Hb expression in non-haematopoietic cells by an EPO inducer ameliorates ischaemic diseases in mice.

Hsu PL, Horng LY, Peng KY, Wu CL, Sung HC, Wu RT.

Br J Pharmacol. 2013 Aug;169(7):1461-76. doi: 10.1111/bph.12197.

33.

Extracellular matrix protein CCN1 regulates cardiomyocyte apoptosis in mice with stress-induced cardiac injury.

Hsu PL, Su BC, Kuok QY, Mo FE.

Cardiovasc Res. 2013 Apr 1;98(1):64-72. doi: 10.1093/cvr/cvt001. Epub 2013 Jan 16.

PMID:
23329650
34.

Mechanical circulatory support for right heart failure: current technology and future outlook.

Hsu PL, Parker J, Egger C, Autschbach R, Schmitz-Rode T, Steinseifer U.

Artif Organs. 2012 Apr;36(4):332-47. doi: 10.1111/j.1525-1594.2011.01366.x. Epub 2011 Dec 8.

PMID:
22150419
35.

Evaluation of hydraulic radial forces on the impeller by the volute in a centrifugal rotary blood pump.

Boehning F, Timms DL, Amaral F, Oliveira L, Graefe R, Hsu PL, Schmitz-Rode T, Steinseifer U.

Artif Organs. 2011 Aug;35(8):818-25. doi: 10.1111/j.1525-1594.2011.01312.x.

PMID:
21843297
36.

A controller for a miniature intra-aortic ventricular assist device.

Hsu PL, Bruch J, McMahon R.

Artif Organs. 2011 Mar;35(3):282-7. doi: 10.1111/j.1525-1594.2010.01060.x. Epub 2010 Nov 30.

PMID:
21114678
37.

Atrial versus ventricular cannulation for a rotary ventricular assist device.

Timms D, Gregory S, Hsu PL, Thomson B, Pearcy M, McNeil K, Fraser J, Steinseifer U.

Artif Organs. 2010 Sep;34(9):714-20. doi: 10.1111/j.1525-1594.2010.01093.x.

PMID:
20883390
38.

Engineering polycrystalline Ni films to improve thickness uniformity of the chemical-vapor-deposition-grown graphene films.

Thiele S, Reina A, Healey P, Kedzierski J, Wyatt P, Hsu PL, Keast C, Schaefer J, Kong J.

Nanotechnology. 2010 Jan 8;21(1):015601. doi: 10.1088/0957-4484/21/1/015601. Epub 2009 Nov 30.

PMID:
19946163
39.

Experiences of interprofessional implementation of a healthcare matrix.

Lee SS, Chiang HC, Chen MC, Chen LS, Hsu PL, Sun IF, Lai CS.

Kaohsiung J Med Sci. 2008 Dec;24(12):634-9. doi: 10.1016/S1607-551X(09)70028-2.

40.

SmartPad: a wireless, adhesive-electrode-free, autonomous ECG acquisition system.

Chen F, Wu H, Hsu PL, Stronger B, Sheridan R, Ma H.

Conf Proc IEEE Eng Med Biol Soc. 2008;2008:2345-8. doi: 10.1109/IEMBS.2008.4649669.

PMID:
19163172
41.

An extended computational model of the circulatory system for designing ventricular assist devices.

Hsu PL, Cheng SJ, Saumarez RC, Dawes WN, McMahon RA.

ASAIO J. 2008 Nov-Dec;54(6):594-9. doi: 10.1097/MAT.0b013e318185e1ce.

PMID:
19033772
42.

Mining three-dimensional anthropometric body surface scanning data for hypertension detection.

Chiu C, Hsu KH, Hsu PL, Hsu CI, Lee PC, Chiou WK, Liu TH, Chuang YC, Hwang CJ.

IEEE Trans Inf Technol Biomed. 2007 May;11(3):264-73.

PMID:
17521076
43.

Protective effect of the immunosuppressant sirolimus against aortic atherosclerosis in apo E-deficient mice.

Elloso MM, Azrolan N, Sehgal SN, Hsu PL, Phiel KL, Kopec CA, Basso MD, Adelman SJ.

Am J Transplant. 2003 May;3(5):562-9.

45.
46.

Biology and therapy of multiple myeloma in 1996.

Barlogie B, Jagannath S, Epstein J, Munshi N, Siegel D, Desikan KR, Feinman R, Hsu PL, von Bremen K, Tricot G.

Semin Hematol. 1997 Jan;34(1 Suppl 1):67-72. Review.

PMID:
9122748
47.
48.

Hodgkin's Disease and Anaplastic Large Cell Lymphoma Revisited. ii. from cytokines to cell lineage.

Hsu SM, Waldron J, Xie SS, Hsu PL.

J Biomed Sci. 1996 Jan;3(1):1-13.

PMID:
11725077
50.

Autocrine and paracrine functions of cytokines in malignant lymphomas.

Hsu SM, Hsu PL.

Biomed Pharmacother. 1994;48(10):433-44. Review.

PMID:
7858153

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