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Items: 19

1.

Structural Basis for the RNA-Guided Ribonuclease Activity of CRISPR-Cas13d.

Zhang C, Konermann S, Brideau NJ, Lotfy P, Wu X, Novick SJ, Strutzenberg T, Griffin PR, Hsu PD, Lyumkis D.

Cell. 2018 Sep 20;175(1):212-223.e17. doi: 10.1016/j.cell.2018.09.001.

PMID:
30241607
2.

Publisher Correction: Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells.

Tycko J, Barrera LA, Huston NC, Friedland AE, Wu X, Gootenberg JS, Abudayyeh OO, Myer VE, Wilson CJ, Hsu PD.

Nat Commun. 2018 Aug 28;9(1):3542. doi: 10.1038/s41467-018-06029-z.

3.

Pairwise library screen systematically interrogates Staphylococcus aureus Cas9 specificity in human cells.

Tycko J, Barrera LA, Huston NC, Friedland AE, Wu X, Gootenberg JS, Abudayyeh OO, Myer VE, Wilson CJ, Hsu PD.

Nat Commun. 2018 Jul 27;9(1):2962. doi: 10.1038/s41467-018-05391-2. Erratum in: Nat Commun. 2018 Aug 28;9(1):3542.

4.

Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors.

Konermann S, Lotfy P, Brideau NJ, Oki J, Shokhirev MN, Hsu PD.

Cell. 2018 Apr 19;173(3):665-676.e14. doi: 10.1016/j.cell.2018.02.033. Epub 2018 Mar 15.

PMID:
29551272
5.

Methods for Optimizing CRISPR-Cas9 Genome Editing Specificity.

Tycko J, Myer VE, Hsu PD.

Mol Cell. 2016 Aug 4;63(3):355-70. doi: 10.1016/j.molcel.2016.07.004. Review.

6.

Structure and Engineering of Francisella novicida Cas9.

Hirano H, Gootenberg JS, Horii T, Abudayyeh OO, Kimura M, Hsu PD, Nakane T, Ishitani R, Hatada I, Zhang F, Nishimasu H, Nureki O.

Cell. 2016 Feb 25;164(5):950-61. doi: 10.1016/j.cell.2016.01.039. Epub 2016 Feb 11.

7.

Delivery and Specificity of CRISPR-Cas9 Genome Editing Technologies for Human Gene Therapy.

Gori JL, Hsu PD, Maeder ML, Shen S, Welstead GG, Bumcrot D.

Hum Gene Ther. 2015 Jul;26(7):443-51. doi: 10.1089/hum.2015.074. Review.

PMID:
26068008
8.

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex.

Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F.

Nature. 2015 Jan 29;517(7536):583-8. doi: 10.1038/nature14136. Epub 2014 Dec 10.

9.

Development and applications of CRISPR-Cas9 for genome engineering.

Hsu PD, Lander ES, Zhang F.

Cell. 2014 Jun 5;157(6):1262-78. doi: 10.1016/j.cell.2014.05.010. Review.

10.

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells.

Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA.

Nat Biotechnol. 2014 Jul;32(7):670-6. doi: 10.1038/nbt.2889. Epub 2014 Apr 20.

11.

RNA-guided genome editing of mammalian cells.

Pyzocha NK, Ran FA, Hsu PD, Zhang F.

Methods Mol Biol. 2014;1114:269-77. doi: 10.1007/978-1-62703-761-7_17.

PMID:
24557909
12.

Crystal structure of Cas9 in complex with guide RNA and target DNA.

Nishimasu H, Ran FA, Hsu PD, Konermann S, Shehata SI, Dohmae N, Ishitani R, Zhang F, Nureki O.

Cell. 2014 Feb 27;156(5):935-49. doi: 10.1016/j.cell.2014.02.001. Epub 2014 Feb 13.

13.

Genome engineering using the CRISPR-Cas9 system.

Ran FA, Hsu PD, Wright J, Agarwala V, Scott DA, Zhang F.

Nat Protoc. 2013 Nov;8(11):2281-2308. doi: 10.1038/nprot.2013.143. Epub 2013 Oct 24.

14.

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity.

Ran FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y, Zhang F.

Cell. 2013 Sep 12;154(6):1380-9. doi: 10.1016/j.cell.2013.08.021. Epub 2013 Aug 29. Erratum in: Cell. 2013 Oct 10;155(2):479-80.

15.

Optical control of mammalian endogenous transcription and epigenetic states.

Konermann S, Brigham MD, Trevino A, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang F.

Nature. 2013 Aug 22;500(7463):472-476. doi: 10.1038/nature12466. Epub 2013 Aug 23.

16.

DNA targeting specificity of RNA-guided Cas9 nucleases.

Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F.

Nat Biotechnol. 2013 Sep;31(9):827-32. doi: 10.1038/nbt.2647. Epub 2013 Jul 21.

17.

Multiplex genome engineering using CRISPR/Cas systems.

Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F.

Science. 2013 Feb 15;339(6121):819-23. doi: 10.1126/science.1231143. Epub 2013 Jan 3.

18.

Dissecting neural function using targeted genome engineering technologies.

Hsu PD, Zhang F.

ACS Chem Neurosci. 2012 Aug 15;3(8):603-10. doi: 10.1021/cn300089k. Epub 2012 Jul 19. Review.

19.

Twinfilin 2 regulates actin filament lengths in cochlear stereocilia.

Peng AW, Belyantseva IA, Hsu PD, Friedman TB, Heller S.

J Neurosci. 2009 Dec 2;29(48):15083-8. doi: 10.1523/JNEUROSCI.2782-09.2009.

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