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Items: 1 to 50 of 221

1.

Direct binding of phosphatidylglycerol at specific sites modulates desensitization of a ligand-gated ion channel.

Tong A, Petroff JT, Hsu FF, Schmidpeter PA, Nimigean CM, Sharp L, Brannigan G, Cheng WW.

Elife. 2019 Nov 14;8. pii: e50766. doi: 10.7554/eLife.50766.

PMID:
31724949
2.

Fatty acid transport protein 4 is required for incorporation of saturated ultralong-chain fatty acids into epidermal ceramides and monoacylglycerols.

Lin MH, Hsu FF, Crumrine D, Meyer J, Elias PM, Miner JH.

Sci Rep. 2019 Sep 13;9(1):13254. doi: 10.1038/s41598-019-49684-y.

3.

Structural and functional evidence that lipoprotein LpqN supports cell envelope biogenesis in Mycobacterium tuberculosis.

Melly GC, Stokas H, Dunaj JL, Hsu FF, Rajavel M, Su CC, Yu EW, Purdy GE.

J Biol Chem. 2019 Oct 25;294(43):15711-15723. doi: 10.1074/jbc.RA119.008781. Epub 2019 Aug 30.

PMID:
31471317
4.

Palmitic Acid-Rich High Fat Diet Exacerbates Experimental Pulmonary Fibrosis by Modulating Endoplasmic Reticulum Stress.

Chu SG, Villalba JA, Liang X, Xiong K, Tsoyi K, Ith B, Ayaub EA, Tatituri RV, Byers DE, Hsu FF, El-Chemaly S, Kim EY, Shi Y, Rosas IO.

Am J Respir Cell Mol Biol. 2019 Aug 28. doi: 10.1165/rcmb.2018-0324OC. [Epub ahead of print]

PMID:
31461627
5.

Corrigendum to "PrfA activation in Listeria monocytogenes increases the sensitivity to class IIa bacteriocins despite impaired expression of the bacteriocin receptor" BBAGEN 2019 Aug 1863/8 Page 1283-1291.

Farizano JV, Masías E, Hsu FF, Salomón RA, Freitag NE, Hebert EM, Minahk C, Saavedra L.

Biochim Biophys Acta Gen Subj. 2019 Nov;1863(11):129404. doi: 10.1016/j.bbagen.2019.07.013. Epub 2019 Aug 13. No abstract available.

PMID:
31420228
6.

N-acyl-O-phosphocholineserines: structures of a novel class of lipids that are biomarkers for Niemann-Pick C1 disease.

Sidhu R, Mondjinou Y, Qian M, Song H, Kumar AB, Hong X, Hsu FF, Dietzen DJ, Yanjanin NM, Porter FD, Berry-Kravis E, Vite CH, Gelb MH, Schaffer JE, Ory DS, Jiang X.

J Lipid Res. 2019 Aug;60(8):1410-1424. doi: 10.1194/jlr.RA119000157. Epub 2019 Jun 14.

PMID:
31201291
7.

Phosphatidylcholine synthesis through cholinephosphate cytidylyltransferase is dispensable in Leishmania major.

Moitra S, Pawlowic MC, Hsu FF, Zhang K.

Sci Rep. 2019 May 20;9(1):7602. doi: 10.1038/s41598-019-44086-6.

8.

PrfA activation in Listeria monocytogenes increases the sensitivity to class IIa bacteriocins despite impaired expression of the bacteriocin receptor.

Farizano JV, Masías E, Hsu FF, Salomón RA, Freitag NE, Hebert EM, Minahk C, Saavedra L.

Biochim Biophys Acta Gen Subj. 2019 Aug;1863(8):1283-1291. doi: 10.1016/j.bbagen.2019.04.021. Epub 2019 May 3. Erratum in: Biochim Biophys Acta Gen Subj. 2019 Nov;1863(11):129404.

PMID:
31059750
9.

Lipid metabolism of phenol-tolerant Rhodococcus opacus strains for lignin bioconversion.

Henson WR, Hsu FF, Dantas G, Moon TS, Foston M.

Biotechnol Biofuels. 2018 Dec 28;11:339. doi: 10.1186/s13068-018-1337-z. eCollection 2018.

10.

Aldehyde adducts inhibit 3,4-dihydroxyphenylacetaldehyde-induced α-synuclein aggregation and toxicity: Implication for Parkinson neuroprotective therapy.

Kumar VB, Hsu FF, Lakshmi VM, Gillespie KN, Burke WJ.

Eur J Pharmacol. 2019 Feb 15;845:65-73. doi: 10.1016/j.ejphar.2018.12.027. Epub 2018 Dec 21.

PMID:
30579934
11.

Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission.

Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang X, Hsu FF, Razani B, Funai K, Lodhi IJ.

J Clin Invest. 2019 Feb 1;129(2):694-711. doi: 10.1172/JCI120606. Epub 2019 Jan 14.

12.

Signal peptide peptidase promotes tumor progression via facilitating FKBP8 degradation.

Hsu FF, Chou YT, Chiang MT, Li FA, Yeh CT, Lee WH, Chau LY.

Oncogene. 2019 Mar;38(10):1688-1701. doi: 10.1038/s41388-018-0539-y. Epub 2018 Oct 22.

PMID:
30348988
13.

Publisher Correction: Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes.

Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Balada-Llasat JM, Torrelles JB, Amarasinghe GK, Mitreva M, Artyomov MN, Hsu FF, Mathema B, Khader SA.

Nat Microbiol. 2018 Nov;3(11):1327. doi: 10.1038/s41564-018-0281-9.

PMID:
30327492
14.

Sterol methyltransferase is required for optimal mitochondrial function and virulence in Leishmania major.

Mukherjee S, Xu W, Hsu FF, Patel J, Huang J, Zhang K.

Mol Microbiol. 2019 Jan;111(1):65-81. doi: 10.1111/mmi.14139. Epub 2018 Oct 21.

PMID:
30260041
15.

Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes.

Howard NC, Marin ND, Ahmed M, Rosa BA, Martin J, Bambouskova M, Sergushichev A, Loginicheva E, Kurepina N, Rangel-Moreno J, Chen L, Kreiswirth BN, Klein RS, Balada-Llasat JM, Torrelles JB, Amarasinghe GK, Mitreva M, Artyomov MN, Hsu FF, Mathema B, Khader SA.

Nat Microbiol. 2018 Oct;3(10):1099-1108. doi: 10.1038/s41564-018-0245-0. Epub 2018 Sep 17. Erratum in: Nat Microbiol. 2018 Nov;3(11):1327.

16.

Correction to: Characterization of Long-Chain Fatty Acid as N-(4-Aminomethylphenyl) Pyridinium Derivative by MALDI LIFT-TOF/TOF Mass Spectrometry.

Frankfater C, Jiang X, Hsu FF.

J Am Soc Mass Spectrom. 2018 Nov;29(11):2282. doi: 10.1007/s13361-018-2050-7.

PMID:
30151678
17.

Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development.

O'Sullivan D, van der Windt GJW, Huang SC, Curtis JD, Chang CH, Buck MD, Qiu J, Smith AM, Lam WY, DiPlato LM, Hsu FF, Birnbaum MJ, Pearce EJ, Pearce EL.

Immunity. 2018 Aug 21;49(2):375-376. doi: 10.1016/j.immuni.2018.07.018. No abstract available.

18.

Mass spectrometry-based shotgun lipidomics - a critical review from the technical point of view.

Hsu FF.

Anal Bioanal Chem. 2018 Oct;410(25):6387-6409. doi: 10.1007/s00216-018-1252-y. Epub 2018 Aug 9. Review.

19.

Mechanism of High-Level Daptomycin Resistance in Corynebacterium striatum.

Goldner NK, Bulow C, Cho K, Wallace M, Hsu FF, Patti GJ, Burnham CA, Schlesinger P, Dantas G.

mSphere. 2018 Aug 8;3(4). pii: e00371-18. doi: 10.1128/mSphereDirect.00371-18.

20.

Loss of lipin 1-mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice.

Schweitzer GG, Collier SL, Chen Z, McCommis KS, Pittman SK, Yoshino J, Matkovich SJ, Hsu FF, Chrast R, Eaton JM, Harris TE, Weihl CC, Finck BN.

FASEB J. 2019 Jan;33(1):652-667. doi: 10.1096/fj.201800361R. Epub 2018 Jul 20.

PMID:
30028636
21.

Characterization of Long-Chain Fatty Acid as N-(4-Aminomethylphenyl) Pyridinium Derivative by MALDI LIFT-TOF/TOF Mass Spectrometry.

Frankfater C, Jiang X, Hsu FF.

J Am Soc Mass Spectrom. 2018 Aug;29(8):1688-1699. doi: 10.1007/s13361-018-1993-z. Epub 2018 May 31. Erratum in: J Am Soc Mass Spectrom. 2018 Nov;29(11):2282.

22.

Diabetes adversely affects phospholipid profiles in human carotid artery endarterectomy plaques.

Zayed MA, Hsu FF, Patterson BW, Yan Y, Naim U, Darwesh M, De Silva G, Yang C, Semenkovich CF.

J Lipid Res. 2018 Apr;59(4):730-738. doi: 10.1194/jlr.M081026. Epub 2018 Feb 24.

23.

Identification of danthron as an isoform-specific inhibitor of HEME OXYGENASE-1/cytochrome P450 reductase interaction with anti-tumor activity.

Chou YT, Hsu FF, Hu DY, Chen YC, Hsu YH, Hsu JT, Chau LY.

J Biomed Sci. 2018 Jan 23;25(1):6. doi: 10.1186/s12929-018-0411-y.

24.

Evaluation of cardiolipin nanodisks as lipid replacement therapy for Barth syndrome

Ikon N, Hsu FF, Shearer J, Forte TM, Ryan RO.

J Biomed Res. 2018 Mar 26;32(2):107-112. doi: 10.7555/JBR.32.20170094.

25.

Retinal de novo lipogenesis coordinates neurotrophic signaling to maintain vision.

Rajagopal R, Zhang S, Wei X, Doggett T, Adak S, Enright J, Shah V, Ling G, Chen S, Yoshino J, Hsu FF, Semenkovich CF.

JCI Insight. 2018 Jan 11;3(1). pii: 97076. doi: 10.1172/jci.insight.97076. eCollection 2018 Jan 11.

26.

Cyclopropane fatty acid synthesis affects cell shape and acid resistance in Leishmania mexicana.

Xu W, Mukherjee S, Ning Y, Hsu FF, Zhang K.

Int J Parasitol. 2018 Mar;48(3-4):245-256. doi: 10.1016/j.ijpara.2017.09.006. Epub 2017 Nov 26.

27.

Mycobacterium tuberculosis is protected from NADPH oxidase and LC3-associated phagocytosis by the LCP protein CpsA.

Köster S, Upadhyay S, Chandra P, Papavinasasundaram K, Yang G, Hassan A, Grigsby SJ, Mittal E, Park HS, Jones V, Hsu FF, Jackson M, Sassetti CM, Philips JA.

Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8711-E8720. doi: 10.1073/pnas.1707792114. Epub 2017 Sep 27. Erratum in: Proc Natl Acad Sci U S A. 2017 Oct 30;:.

28.

PexRAP Inhibits PRDM16-Mediated Thermogenic Gene Expression.

Lodhi IJ, Dean JM, He A, Park H, Tan M, Feng C, Song H, Hsu FF, Semenkovich CF.

Cell Rep. 2017 Sep 19;20(12):2766-2774. doi: 10.1016/j.celrep.2017.08.077.

29.

A multifunctional nanocarrier for efficient TRAIL-based gene therapy against hepatocellular carcinoma with desmoplasia in mice.

Liu CH, Chern GJ, Hsu FF, Huang KW, Sung YC, Huang HC, Qiu JT, Wang SK, Lin CC, Wu CH, Wu HC, Liu JY, Chen Y.

Hepatology. 2018 Mar;67(3):899-913. doi: 10.1002/hep.29513. Epub 2018 Jan 29.

PMID:
28885731
30.

Acetylation is essential for nuclear heme oxygenase-1-enhanced tumor growth and invasiveness.

Hsu FF, Chiang MT, Li FA, Yeh CT, Lee WH, Chau LY.

Oncogene. 2017 Dec 7;36(49):6805-6814. doi: 10.1038/onc.2017.294. Epub 2017 Aug 28.

PMID:
28846111
31.

The Mycobacterium tuberculosis MmpL11 Cell Wall Lipid Transporter Is Important for Biofilm Formation, Intracellular Growth, and Nonreplicating Persistence.

Wright CC, Hsu FF, Arnett E, Dunaj JL, Davidson PM, Pacheco SA, Harriff MJ, Lewinsohn DM, Schlesinger LS, Purdy GE.

Infect Immun. 2017 Jul 19;85(8). pii: e00131-17. doi: 10.1128/IAI.00131-17. Print 2017 Aug.

32.

Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors.

Chen Y, Liu YC, Sung YC, Ramjiawan RR, Lin TT, Chang CC, Jeng KS, Chang CF, Liu CH, Gao DY, Hsu FF, Duyverman AM, Kitahara S, Huang P, Dima S, Popescu I, Flaherty KT, Zhu AX, Bardeesy N, Jain RK, Benes CH, Duda DG.

Sci Rep. 2017 Mar 9;7:44123. doi: 10.1038/srep44123.

33.

Linear ion-trap MSn with high-resolution MS reveals structural diversity of 1-O-acylceramide family in mouse epidermis.

Lin MH, Miner JH, Turk J, Hsu FF.

J Lipid Res. 2017 Apr;58(4):772-782. doi: 10.1194/jlr.D071647. Epub 2017 Feb 2.

34.

Psychosis with suicide attempt in Sneddon syndrome.

Hsu FF, Chung KH.

Psychiatry Clin Neurosci. 2017 Feb;71(2):147-148. doi: 10.1111/pcn.12489. Epub 2017 Jan 3. No abstract available.

35.

Accumulation of long-chain bases in yeast promotes their conversion to a long-chain base vinyl ether.

Martínez-Montañés F, Lone MA, Hsu FF, Schneiter R.

J Lipid Res. 2016 Nov;57(11):2040-2050. Epub 2016 Aug 25.

36.

Complete structural characterization of ceramides as [M-H]- ions by multiple-stage linear ion trap mass spectrometry.

Hsu FF.

Biochimie. 2016 Nov;130:63-75. doi: 10.1016/j.biochi.2016.07.012. Epub 2016 Aug 12.

37.

Dual-Functional Nanoparticles Targeting CXCR4 and Delivering Antiangiogenic siRNA Ameliorate Liver Fibrosis.

Liu CH, Chan KM, Chiang T, Liu JY, Chern GG, Hsu FF, Wu YH, Liu YC, Chen Y.

Mol Pharm. 2016 Jul 5;13(7):2253-62. doi: 10.1021/acs.molpharmaceut.5b00913. Epub 2016 Jun 3.

PMID:
27224003
38.

Development of a bile acid-based newborn screen for Niemann-Pick disease type C.

Jiang X, Sidhu R, Mydock-McGrane L, Hsu FF, Covey DF, Scherrer DE, Earley B, Gale SE, Farhat NY, Porter FD, Dietzen DJ, Orsini JJ, Berry-Kravis E, Zhang X, Reunert J, Marquardt T, Runz H, Giugliani R, Schaffer JE, Ory DS.

Sci Transl Med. 2016 May 4;8(337):337ra63. doi: 10.1126/scitranslmed.aaf2326.

39.

Wnt Protein Signaling Reduces Nuclear Acetyl-CoA Levels to Suppress Gene Expression during Osteoblast Differentiation.

Karner CM, Esen E, Chen J, Hsu FF, Turk J, Long F.

J Biol Chem. 2016 Jun 17;291(25):13028-39. doi: 10.1074/jbc.M115.708578. Epub 2016 Apr 20.

40.

Plasmenylethanolamine synthesis in Leishmania major.

Pawlowic MC, Hsu FF, Moitra S, Biyani N, Zhang K.

Mol Microbiol. 2016 Jul;101(2):238-49. doi: 10.1111/mmi.13387. Epub 2016 May 6.

41.

Characterization of Hydroxyphthioceranoic and Phthioceranoic Acids by Charge-Switch Derivatization and CID Tandem Mass Spectrometry.

Hsu FF.

J Am Soc Mass Spectrom. 2016 Apr;27(4):622-32. doi: 10.1007/s13361-015-1328-2. Epub 2016 Jan 4.

42.

Characterization of phthiocerol and phthiodiolone dimycocerosate esters of M. tuberculosis by multiple-stage linear ion-trap MS.

Flentie KN, Stallings CL, Turk J, Minnaard AJ, Hsu FF.

J Lipid Res. 2016 Jan;57(1):142-55. doi: 10.1194/jlr.D063735. Epub 2015 Nov 16.

43.

Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells.

Wolf BJ, Tatituri RV, Almeida CF, Le Nours J, Bhowruth V, Johnson D, Uldrich AP, Hsu FF, Brigl M, Besra GS, Rossjohn J, Godfrey DI, Brenner MB.

J Immunol. 2015 Sep 15;195(6):2540-51. doi: 10.4049/jimmunol.1501019. Epub 2015 Aug 7.

44.

Exogenous cardiolipin localizes to mitochondria and prevents TAZ knockdown-induced apoptosis in myeloid progenitor cells.

Ikon N, Su B, Hsu FF, Forte TM, Ryan RO.

Biochem Biophys Res Commun. 2015 Aug 21;464(2):580-5. doi: 10.1016/j.bbrc.2015.07.012. Epub 2015 Jul 9.

45.

Signal peptide peptidase-mediated nuclear localization of heme oxygenase-1 promotes cancer cell proliferation and invasion independent of its enzymatic activity.

Hsu FF, Yeh CT, Sun YJ, Chiang MT, Lan WM, Li FA, Lee WH, Chau LY.

Oncogene. 2015 Apr 30;34(18):2410-1. doi: 10.1038/onc.2014.464. No abstract available.

PMID:
25924715
46.

Malaria parasites produce volatile mosquito attractants.

Kelly M, Su CY, Schaber C, Crowley JR, Hsu FF, Carlson JR, Odom AR.

MBio. 2015 Mar 24;6(2). pii: e00235-15. doi: 10.1128/mBio.00235-15.

47.

Characterization of polar lipids of Listeria monocytogenes by HCD and low-energy CAD linear ion-trap mass spectrometry with electrospray ionization.

Tatituri RV, Wolf BJ, Brenner MB, Turk J, Hsu FF.

Anal Bioanal Chem. 2015 Mar;407(9):2519-28. doi: 10.1007/s00216-015-8480-1. Epub 2015 Feb 6.

48.

Peroxisomal lipid synthesis regulates inflammation by sustaining neutrophil membrane phospholipid composition and viability.

Lodhi IJ, Wei X, Yin L, Feng C, Adak S, Abou-Ezzi G, Hsu FF, Link DC, Semenkovich CF.

Cell Metab. 2015 Jan 6;21(1):51-64. doi: 10.1016/j.cmet.2014.12.002.

49.

Sterol biosynthesis is required for heat resistance but not extracellular survival in leishmania.

Xu W, Hsu FF, Baykal E, Huang J, Zhang K.

PLoS Pathog. 2014 Oct 23;10(10):e1004427. doi: 10.1371/journal.ppat.1004427. eCollection 2014 Oct.

50.

Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction.

Brennan PJ, Tatituri RV, Heiss C, Watts GF, Hsu FF, Veerapen N, Cox LR, Azadi P, Besra GS, Brenner MB.

Proc Natl Acad Sci U S A. 2014 Sep 16;111(37):13433-8. doi: 10.1073/pnas.1415357111. Epub 2014 Sep 2.

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