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Items: 1 to 50 of 84

1.

NHC-Mediated Synthesis of Tricyclic Spirocarbocycles via an Intramolecular Stetter Reaction of Cyclic Enal-Enones.

Hsu DS, Liang SP.

J Org Chem. 2020 Jan 17;85(2):1270-1278. doi: 10.1021/acs.joc.9b02881. Epub 2019 Dec 17.

PMID:
31794214
2.

Single-Cell RNA Sequencing Identifies Yes-Associated Protein 1-Dependent Hepatic Mesothelial Progenitors in Fibrolamellar Carcinoma.

Jewell ML, Gibson JR, Guy CD, Hyun J, Du K, Oh SH, Premont RT, Hsu DS, Ribar T, Gregory SG, Diehl AME.

Am J Pathol. 2020 Jan;190(1):93-107. doi: 10.1016/j.ajpath.2019.09.018. Epub 2019 Oct 24.

PMID:
31669305
3.

Total Synthesis and Determination of the Absolute Configuration of Parimycin.

Hsu DS, Huang JY.

Org Lett. 2019 Sep 20;21(18):7665-7668. doi: 10.1021/acs.orglett.9b02999. Epub 2019 Sep 12.

PMID:
31512884
4.

Construction of Spirofused Tricyclic Frameworks by NHC-Catalyzed Intramolecular Stetter Reaction of a Benzaldehyde Tether with a Cyclic Enone.

Hsu DS, Cheng CY.

J Org Chem. 2019 Sep 6;84(17):10832-10842. doi: 10.1021/acs.joc.9b01403. Epub 2019 Aug 22.

PMID:
31397574
5.

Dietary methionine influences therapy in mouse cancer models and alters human metabolism.

Gao X, Sanderson SM, Dai Z, Reid MA, Cooper DE, Lu M, Richie JP Jr, Ciccarella A, Calcagnotto A, Mikhael PG, Mentch SJ, Liu J, Ables G, Kirsch DG, Hsu DS, Nichenametla SN, Locasale JW.

Nature. 2019 Aug;572(7769):397-401. doi: 10.1038/s41586-019-1437-3. Epub 2019 Jul 31.

PMID:
31367041
6.

Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds.

Tian X, Werner ME, Roche KC, Hanson AD, Foote HP, Yu SK, Warner SB, Copp JA, Lara H, Wauthier EL, Caster JM, Herring LE, Zhang L, Tepper JE, Hsu DS, Zhang T, Reid LM, Wang AZ.

Nat Biomed Eng. 2018 Jun;2(6):443-452. doi: 10.1038/s41551-018-0231-0. Epub 2018 Apr 23.

PMID:
31011191
7.

Author Correction: Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition.

Yang MH, Hsu DS, Wang HW, Wang HJ, Lan HY, Yang WH, Huang CH, Kao SY, Tzeng CH, Tai SK, Chang SY, Lee OK, Wu KJ.

Nat Cell Biol. 2019 Apr;21(4):533. doi: 10.1038/s41556-019-0290-9.

PMID:
30833696
8.

Snail-induced claudin-11 prompts collective migration for tumour progression.

Li CF, Chen JY, Ho YH, Hsu WH, Wu LC, Lan HY, Hsu DS, Tai SK, Chang YC, Yang MH.

Nat Cell Biol. 2019 Feb;21(2):251-262. doi: 10.1038/s41556-018-0268-z. Epub 2019 Jan 21.

PMID:
30664792
9.

Exercise inhibits tumor growth and central carbon metabolism in patient-derived xenograft models of colorectal cancer.

Lu M, Sanderson SM, Zessin A, Ashcraft KA, Jones LW, Dewhirst MW, Locasale JW, Hsu DS.

Cancer Metab. 2018 Nov 15;6:14. doi: 10.1186/s40170-018-0190-7. eCollection 2018.

10.

Single-Cell Transcriptomics Reveals Heterogeneity and Drug Response of Human Colorectal Cancer Organoids.

Chen KY, Srinivasan T, Lin C, Tung KL, Gao Z, Hsu DS, Lipkin SM, Shen X.

Conf Proc IEEE Eng Med Biol Soc. 2018 Jul;2018:2378-2381. doi: 10.1109/EMBC.2018.8512784.

11.

Organ-specific metastases obtained by culturing colorectal cancer cells on tissue-specific decellularized scaffolds.

Tian X, Werner ME, Roche KC, Hanson AD, Foote HP, Yu SK, Warner SB, Copp JA, Lara H, Wauthier EL, Caster JM, Herring LE, Zhang L, Tepper JE, Hsu DS, Zhang T, Reid LM, Wang AZ.

Nat Biomed Eng. 2018;2:443-452. Epub 2018 Apr 23.

12.

Targeting HPV16 DNA using CRISPR/Cas inhibits anal cancer growth in vivo.

Hsu DS, Kornepati AV, Glover W, Kennedy EM, Cullen BR.

Future Virol. 2018 Jul;13(7):475-482. doi: 10.2217/fvl-2018-0010. Epub 2018 Jun 12.

13.

Total synthesis and structural revision of (±)-nidemone.

Hsu DS, Liou CY.

Org Biomol Chem. 2018 Jul 11;16(27):4990-4995. doi: 10.1039/c8ob01207e.

PMID:
29938737
14.

Epidermal Growth Factor and Granulocyte Colony Stimulating Factor Signaling Are Synergistic for Hematopoietic Regeneration.

Piryani SO, Kam AYF, Kliassov EG, Chen BJ, Spector NL, Chute JP, Hsu DS, Chao NJ, Doan PL.

Stem Cells. 2018 Feb;36(2):252-264. doi: 10.1002/stem.2731. Epub 2017 Nov 10.

15.

Total Synthesis of the Proposed Structure of (±)-Nidemone.

Hsu DS, Yeh JY, Cheng CY.

Org Lett. 2017 Oct 20;19(20):5549-5552. doi: 10.1021/acs.orglett.7b02645. Epub 2017 Sep 29.

PMID:
28960080
16.

Cystine addiction of triple-negative breast cancer associated with EMT augmented death signaling.

Tang X, Ding CK, Wu J, Sjol J, Wardell S, Spasojevic I, George D, McDonnell DP, Hsu DS, Chang JT, Chi JT.

Oncogene. 2017 Jul 27;36(30):4379. doi: 10.1038/onc.2017.192. Epub 2017 Jun 12.

PMID:
28604749
17.

Lymphotoxin-β Interacts with Methylated EGFR to Mediate Acquired Resistance to Cetuximab in Head and Neck Cancer.

Hsu DS, Hwang WL, Yuh CH, Chu CH, Ho YH, Chen PB, Lin HS, Lin HK, Wu SP, Lin CY, Hsu WH, Lan HY, Wang HJ, Tai SK, Hung MC, Yang MH.

Clin Cancer Res. 2017 Aug 1;23(15):4388-4401. doi: 10.1158/1078-0432.CCR-16-1955. Epub 2017 Feb 14.

18.

Activation of the mTOR Pathway by Oxaliplatin in the Treatment of Colorectal Cancer Liver Metastasis.

Lu M, Zessin AS, Glover W, Hsu DS.

PLoS One. 2017 Jan 6;12(1):e0169439. doi: 10.1371/journal.pone.0169439. eCollection 2017.

19.

Cystine addiction of triple-negative breast cancer associated with EMT augmented death signaling.

Tang X, Ding CK, Wu J, Sjol J, Wardell S, Spasojevic I, George D, McDonnell DP, Hsu DS, Chang JT, Chi JT.

Oncogene. 2017 Jul 27;36(30):4235-4242. doi: 10.1038/onc.2016.394. Epub 2016 Nov 21. Erratum in: Oncogene. 2017 Jun 12;:.

20.

Application of Carbohydrate-Templated Asymmetric Diels-Alder Reaction to the Syntheses of ent-Penicillones A and B.

Weng CH, Hsu DS, Liao CC.

J Org Chem. 2016 Nov 18;81(22):11421-11426. Epub 2016 Oct 13.

PMID:
27723310
21.

Development of a Novel c-MET-Based CTC Detection Platform.

Zhang T, Boominathan R, Foulk B, Rao C, Kemeny G, Strickler JH, Abbruzzese JL, Harrison MR, Hsu DS, Healy P, Li J, Pi C, Prendergast KM, Hobbs C, Gemberling S, George DJ, Hurwitz HI, Connelly M, Garcia-Blanco MA, Armstrong AJ.

Mol Cancer Res. 2016 Jun;14(6):539-47. doi: 10.1158/1541-7786.MCR-16-0011. Epub 2016 Mar 7.

22.

Primary high-grade neuroendocrine carcinoma emerging from an adenomatous polyp in the setting of familial adenomatous polyposis.

Detweiler CJ, Cardona DM, Hsu DS, McCall SJ.

BMJ Case Rep. 2016 Feb 16;2016. pii: bcr2015214206. doi: 10.1136/bcr-2015-214206.

23.

Cystine Deprivation Triggers Programmed Necrosis in VHL-Deficient Renal Cell Carcinomas.

Tang X, Wu J, Ding CK, Lu M, Keenan MM, Lin CC, Lin CA, Wang CC, George D, Hsu DS, Chi JT.

Cancer Res. 2016 Apr 1;76(7):1892-903. doi: 10.1158/0008-5472.CAN-15-2328. Epub 2016 Feb 1.

24.

Multicomponent reactions of phosphines, enynedioates and benzylidene malononitriles generated highly substituted cyclopentenes through an unexpected phosphine α-addition-δ-evolvement of an anion pathway.

Chuang SC, Sung SP, Deng JC, Chiou MF, Hsu DS.

Org Biomol Chem. 2016 Feb 21;14(7):2306-17. doi: 10.1039/c5ob02445e. Epub 2016 Jan 25.

PMID:
26806006
25.

Mismatch repair gone awry: Management of Lynch syndrome.

Zhang T, Boswell EL, McCall SJ, Hsu DS.

Crit Rev Oncol Hematol. 2015 Mar;93(3):170-9. doi: 10.1016/j.critrevonc.2014.10.005. Epub 2014 Oct 12. Review.

PMID:
25459670
26.

Adjuvant chemotherapy for t1 node-positive colon cancers provides significant survival benefit.

Ganapathi AM, Speicher PJ, Englum BR, Castleberry AW, Migaly J, Hsu DS, Mantyh CR.

Dis Colon Rectum. 2014 Dec;57(12):1341-8. doi: 10.1097/DCR.0000000000000245.

27.

Acetylation of snail modulates the cytokinome of cancer cells to enhance the recruitment of macrophages.

Hsu DS, Wang HJ, Tai SK, Chou CH, Hsieh CH, Chiu PH, Chen NJ, Yang MH.

Cancer Cell. 2014 Oct 13;26(4):534-48. doi: 10.1016/j.ccell.2014.09.002.

28.

The genomic landscape of mantle cell lymphoma is related to the epigenetically determined chromatin state of normal B cells.

Zhang J, Jima D, Moffitt AB, Liu Q, Czader M, Hsi ED, Fedoriw Y, Dunphy CH, Richards KL, Gill JI, Sun Z, Love C, Scotland P, Lock E, Levy S, Hsu DS, Dunson D, Dave SS.

Blood. 2014 May 8;123(19):2988-96. doi: 10.1182/blood-2013-07-517177. Epub 2014 Mar 28.

29.

Use of molecular biomarkers to inform adjuvant therapy for colon cancer.

Mettu NB, Hurwitz H, Hsu DS.

Oncology (Williston Park). 2013 Aug;27(8):746-54. Review.

30.

Novel adenoviral vector induces T-cell responses despite anti-adenoviral neutralizing antibodies in colorectal cancer patients.

Morse MA, Chaudhry A, Gabitzsch ES, Hobeika AC, Osada T, Clay TM, Amalfitano A, Burnett BK, Devi GR, Hsu DS, Xu Y, Balcaitis S, Dua R, Nguyen S, Balint JP Jr, Jones FR, Lyerly HK.

Cancer Immunol Immunother. 2013 Aug;62(8):1293-301. doi: 10.1007/s00262-013-1400-3. Epub 2013 Apr 30.

31.

Preparation of L-vancosamine-related glycosyl donors.

Kitamura K, Shigeta M, Maezawa Y, Watanabe Y, Hsu DS, Ando Y, Matsumoto T, Suzuki K.

J Antibiot (Tokyo). 2013 Mar;66(3):131-9. doi: 10.1038/ja.2013.2. Epub 2013 Feb 20.

PMID:
23423169
32.

Chromosome instability modulated by BMI1-AURKA signaling drives progression in head and neck cancer.

Chou CH, Yang NK, Liu TY, Tai SK, Hsu DS, Chen YW, Chen YJ, Chang CC, Tzeng CH, Yang MH.

Cancer Res. 2013 Jan 15;73(2):953-66. doi: 10.1158/0008-5472.CAN-12-2397. Epub 2012 Nov 30. Erratum in: Cancer Res. 2017 Jun 1;77(11):3125-3126.

33.

Total syntheses of cladoacetals A and B: confirmation of absolute configurations.

Hsu DS, Lin SC.

J Org Chem. 2012 Jul 20;77(14):6139-46. doi: 10.1021/jo300923e. Epub 2012 Jul 3.

PMID:
22734963
34.

Histological and molecular evaluation of patient-derived colorectal cancer explants.

Uronis JM, Osada T, McCall S, Yang XY, Mantyh C, Morse MA, Lyerly HK, Clary BM, Hsu DS.

PLoS One. 2012;7(6):e38422. doi: 10.1371/journal.pone.0038422. Epub 2012 Jun 4.

35.

Retraction in part: A genomic approach to identify molecular pathways associated with chemotherapy resistance.

Riedel RF, Porrello A, Pontzer E, Chenette EJ, Hsu DS, Balakumaran B, Potti A, Nevins J, Febbo PC.

Mol Cancer Ther. 2012 May;11(5):1214-5. doi: 10.1158/1535-7163.MCT-12-0210. Epub 2012 Mar 29. No abstract available.

36.

Room-temperature B(OAc)3-promoted Diels-Alder reaction of juglone with styrenes: total syntheses of tetrangulol and anhydrolandomycinone.

Hsu DS, Huang JY.

J Org Chem. 2012 Mar 16;77(6):2659-66. doi: 10.1021/jo202448e. Epub 2012 Mar 2.

PMID:
22356281
37.

Characterization of an oxaliplatin sensitivity predictor in a preclinical murine model of colorectal cancer.

Kim MK, Osada T, Barry WT, Yang XY, Freedman JA, Tsamis KA, Datto M, Clary BM, Clay T, Morse MA, Febbo PG, Lyerly HK, Hsu DS.

Mol Cancer Ther. 2012 Jul;11(7):1500-1509. doi: 10.1158/1535-7163.MCT-11-0937. Epub 2012 Feb 16.

38.

Gene expression profiling of peritoneal metastases from appendiceal and colon cancer demonstrates unique biologic signatures and predicts patient outcomes.

Levine EA, Blazer DG 3rd, Kim MK, Shen P, Stewart JH 4th, Guy C, Hsu DS.

J Am Coll Surg. 2012 Apr;214(4):599-606; discussion 606-7. doi: 10.1016/j.jamcollsurg.2011.12.028. Epub 2012 Feb 17.

39.

Retraction: Acharya CR, et al. Gene expression signatures, clinicopathological features, and individualized therapy in breast cancer. JAMA. 2008;299(13):1574-1587.

Acharya CR, Hsu DS, Anders CK, Anguiano A, Salter KH, Walters KS, Redman RC, Tuchman SA, Moylan CA, Mukherjee S, Barry WT, Dressman HK, Ginsburg GS, Marcom KP, Garman KS, Lyman GH, Nevins JR, Potti A.

JAMA. 2012 Feb 1;307(5):453. doi: 10.1001/jama.2012.2. Epub 2012 Jan 6. No abstract available.

PMID:
22228686
40.

A methodology for utilization of predictive genomic signatures in FFPE samples.

Freedman JA, Augustine CK, Selim AM, Holshausen KC, Wei Z, Tsamis KA, Hsu DS, Dressman HK, Barry WT, Tyler DS, Nevins JR.

BMC Med Genomics. 2011 Jul 11;4:58. doi: 10.1186/1755-8794-4-58.

41.

CSPG4 protein as a new target for the antibody-based immunotherapy of triple-negative breast cancer.

Wang X, Osada T, Wang Y, Yu L, Sakakura K, Katayama A, McCarthy JB, Brufsky A, Chivukula M, Khoury T, Hsu DS, Barry WT, Lyerly HK, Clay TM, Ferrone S.

J Natl Cancer Inst. 2010 Oct 6;102(19):1496-512. doi: 10.1093/jnci/djq343. Epub 2010 Sep 17.

42.

Regulation of excision repair cross-complementation group 1 by Snail contributes to cisplatin resistance in head and neck cancer.

Hsu DS, Lan HY, Huang CH, Tai SK, Chang SY, Tsai TL, Chang CC, Tzeng CH, Wu KJ, Kao JY, Yang MH.

Clin Cancer Res. 2010 Sep 15;16(18):4561-71. doi: 10.1158/1078-0432.CCR-10-0593. Epub 2010 Sep 7.

43.

Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition.

Yang MH, Hsu DS, Wang HW, Wang HJ, Lan HY, Yang WH, Huang CH, Kao SY, Tzeng CH, Tai SK, Chang SY, Lee OK, Wu KJ.

Nat Cell Biol. 2010 Oct;12(10):982-92. doi: 10.1038/ncb2099. Epub 2010 Sep 5. Erratum in: Nat Cell Biol. 2019 Apr;21(4):533.

PMID:
20818389
44.

Immune signatures predict prognosis in localized cancer.

Hsu DS, Kim MK, Balakumaran BS, Acharya CR, Anders CK, Clay T, Lyerly HK, Drake CG, Morse MA, Febbo PG.

Cancer Invest. 2010 Aug;28(7):765-73. doi: 10.3109/07357900903095755.

45.

Identification of increased NBS1 expression as a prognostic marker of squamous cell carcinoma of the oral cavity.

Hsu DS, Chang SY, Liu CJ, Tzeng CH, Wu KJ, Kao JY, Yang MH.

Cancer Sci. 2010 Apr;101(4):1029-37. doi: 10.1111/j.1349-7006.2009.01471.x. Epub 2009 Dec 15.

47.

MYC activity mitigates response to rapamycin in prostate cancer through eukaryotic initiation factor 4E-binding protein 1-mediated inhibition of autophagy.

Balakumaran BS, Porrello A, Hsu DS, Glover W, Foye A, Leung JY, Sullivan BA, Hahn WC, Loda M, Febbo PG.

Cancer Res. 2009 Oct 1;69(19):7803-10. doi: 10.1158/0008-5472.CAN-09-0910. Epub 2009 Sep 22.

48.

Characterizing the developmental pathways TTF-1, NKX2-8, and PAX9 in lung cancer.

Hsu DS, Acharya CR, Balakumaran BS, Riedel RF, Kim MK, Stevenson M, Tuchman S, Mukherjee S, Barry W, Dressman HK, Nevins JR, Powers S, Mu D, Potti A.

Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5312-7. doi: 10.1073/pnas.0900827106. Epub 2009 Mar 11. Erratum in: Proc Natl Acad Sci U S A. 2011 Aug 30;108(35):14705.

49.

A genomic approach to identify molecular pathways associated with chemotherapy resistance.

Riedel RF, Porrello A, Pontzer E, Chenette EJ, Hsu DS, Balakumaran B, Potti A, Nevins J, Febbo PG.

Mol Cancer Ther. 2008 Oct;7(10):3141-9. doi: 10.1158/1535-7163.MCT-08-0642. Erratum in: Mol Cancer Ther. 2012 May;11(5):1214-5.

50.

Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression.

Anders CK, Hsu DS, Broadwater G, Acharya CR, Foekens JA, Zhang Y, Wang Y, Marcom PK, Marks JR, Febbo PG, Nevins JR, Potti A, Blackwell KL.

J Clin Oncol. 2008 Jul 10;26(20):3324-30. doi: 10.1200/JCO.2007.14.2471. Erratum in: J Clin Oncol. 2011 Sep 20;29(27):3721.

PMID:
18612148

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