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Items: 1 to 50 of 104

1.

A small molecule CCR2 antagonist depletes tumor macrophages and synergizes with anti-PD1 in a murine model of cutaneous T cell lymphoma (CTCL).

Wu X, Singh R, Hsu DK, Zhou Y, Yu S, Han D, Shi Z, Huynh M, Campbell JJ, Hwang ST.

J Invest Dermatol. 2020 Jan 13. pii: S0022-202X(19)33562-6. doi: 10.1016/j.jid.2019.11.018. [Epub ahead of print]

PMID:
31945344
2.

IL-10 is overexpressed in human cutaneous T-cell lymphoma and is required for maximal tumor growth in a mouse model.

Wu X, Hsu DK, Wang KH, Huang Y, Mendoza L, Zhou Y, Hwang ST.

Leuk Lymphoma. 2019 May;60(5):1244-1252. doi: 10.1080/10428194.2018.1516037. Epub 2018 Oct 2.

PMID:
30277131
3.

Cytosolic galectin-3 and -8 regulate antibacterial autophagy through differential recognition of host glycans on damaged phagosomes.

Weng IC, Chen HL, Lo TH, Lin WH, Chen HY, Hsu DK, Liu FT.

Glycobiology. 2018 Jun 1;28(6):392-405. doi: 10.1093/glycob/cwy017.

PMID:
29800364
4.

Galectin-3 regulates inflammasome activation in cholestatic liver injury.

Tian J, Yang G, Chen HY, Hsu DK, Tomilov A, Olson KA, Dehnad A, Fish SR, Cortopassi G, Zhao B, Liu FT, Gershwin ME, Török NJ, Jiang JX.

FASEB J. 2016 Dec;30(12):4202-4213. Epub 2016 Sep 14.

5.

Galectin-3 Plays an Important Role in Innate Immunity to Gastric Infection by Helicobacter pylori.

Park AM, Hagiwara S, Hsu DK, Liu FT, Yoshie O.

Infect Immun. 2016 Mar 24;84(4):1184-1193. doi: 10.1128/IAI.01299-15. Print 2016 Apr.

6.

Galectin-7 Regulates Keratinocyte Proliferation and Differentiation through JNK-miR-203-p63 Signaling.

Chen HL, Chiang PC, Lo CH, Lo YH, Hsu DK, Chen HY, Liu FT.

J Invest Dermatol. 2016 Jan;136(1):182-191. doi: 10.1038/JID.2015.366.

7.

Chlamydophila psittaci-negative ocular adnexal marginal zone lymphomas express self polyreactive B-cell receptors.

Zhu D, Bhatt S, Lu X, Guo F, Veelken H, Hsu DK, Liu FT, Alvarez Cubela S, Kunkalla K, Vega F, Chapman-Fredricks JR, Lossos IS.

Leukemia. 2015 Jul;29(7):1587-99. doi: 10.1038/leu.2015.39. Epub 2015 Feb 13.

PMID:
25676418
8.

Analysis of the intracellular role of galectins in cell growth and apoptosis.

Hsu DK, Yang RY, Saegusa J, Liu FT.

Methods Mol Biol. 2015;1207:451-63. doi: 10.1007/978-1-4939-1396-1_29.

9.

Galectin-3 promotes HIV-1 budding via association with Alix and Gag p6.

Wang SF, Tsao CH, Lin YT, Hsu DK, Chiang ML, Lo CH, Chien FC, Chen P, Arthur Chen YM, Chen HY, Liu FT.

Glycobiology. 2014 Nov;24(11):1022-35. doi: 10.1093/glycob/cwu064. Epub 2014 Jul 4.

10.

Galectin-3 modulates Th17 responses by regulating dendritic cell cytokines.

Fermin Lee A, Chen HY, Wan L, Wu SY, Yu JS, Huang AC, Miaw SC, Hsu DK, Wu-Hsieh BA, Liu FT.

Am J Pathol. 2013 Oct;183(4):1209-1222. doi: 10.1016/j.ajpath.2013.06.017. Epub 2013 Aug 3.

11.

Galectin-3 regulates the innate immune response of human monocytes.

Chung AW, Sieling PA, Schenk M, Teles RM, Krutzik SR, Hsu DK, Liu FT, Sarno EN, Rea TH, Stenger S, Modlin RL, Lee DJ.

J Infect Dis. 2013 Mar 15;207(6):947-56. doi: 10.1093/infdis/jis920. Epub 2012 Dec 18.

12.

Deletion of galectin-3 exacerbates microglial activation and accelerates disease progression and demise in a SOD1(G93A) mouse model of amyotrophic lateral sclerosis.

Lerman BJ, Hoffman EP, Sutherland ML, Bouri K, Hsu DK, Liu FT, Rothstein JD, Knoblach SM.

Brain Behav. 2012 Sep;2(5):563-75. doi: 10.1002/brb3.75. Epub 2012 Jul 23.

13.

Galectin-3 binds to CD45 on diffuse large B-cell lymphoma cells to regulate susceptibility to cell death.

Clark MC, Pang M, Hsu DK, Liu FT, de Vos S, Gascoyne RD, Said J, Baum LG.

Blood. 2012 Nov 29;120(23):4635-44. doi: 10.1182/blood-2012-06-438234. Epub 2012 Oct 12.

14.

Comparative transcriptomic analyses of atopic dermatitis and psoriasis reveal shared neutrophilic inflammation.

Choy DF, Hsu DK, Seshasayee D, Fung MA, Modrusan Z, Martin F, Liu FT, Arron JR.

J Allergy Clin Immunol. 2012 Dec;130(6):1335-43.e5. doi: 10.1016/j.jaci.2012.06.044. Epub 2012 Aug 22.

15.

Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration.

Liu W, Hsu DK, Chen HY, Yang RY, Carraway KL 3rd, Isseroff RR, Liu FT.

J Invest Dermatol. 2012 Dec;132(12):2828-37. doi: 10.1038/jid.2012.211. Epub 2012 Jul 12.

16.

The involvement of the spleen during chronic phase of Schistosoma mansoni infection in galectin-3-/- mice.

Brand C, Oliveira FL, Takiya CM, Palumbo A Jr, Hsu DK, Liu FT, Borojevic R, Chammas R, El-Cheikh MC.

Histol Histopathol. 2012 Aug;27(8):1109-20. doi: 10.14670/HH-27.1109.

PMID:
22763883
17.

The roles of Galectin-3 in autoimmunity and tumor progression.

Radosavljevic G, Volarevic V, Jovanovic I, Milovanovic M, Pejnovic N, Arsenijevic N, Hsu DK, Lukic ML.

Immunol Res. 2012 Apr;52(1-2):100-10. doi: 10.1007/s12026-012-8286-6. Review.

PMID:
22418727
18.

Galectins in acute and chronic inflammation.

Liu FT, Yang RY, Hsu DK.

Ann N Y Acad Sci. 2012 Apr;1253:80-91. doi: 10.1111/j.1749-6632.2011.06386.x. Epub 2012 Feb 13. Review.

PMID:
22329844
19.

The promigratory activity of the matricellular protein galectin-3 depends on the activation of PI-3 kinase.

Melo FH, Butera D, Junqueira Mde S, Hsu DK, da Silva AM, Liu FT, Santos MF, Chammas R.

PLoS One. 2011;6(12):e29313. doi: 10.1371/journal.pone.0029313. Epub 2011 Dec 28.

20.

Contribution of spinal galectin-3 to acute herpetic allodynia in mice.

Takasaki I, Taniguchi K, Komatsu F, Sasaki A, Andoh T, Nojima H, Shiraki K, Hsu DK, Liu FT, Kato I, Hiraga K, Kuraishi Y.

Pain. 2012 Mar;153(3):585-92. doi: 10.1016/j.pain.2011.11.022. Epub 2011 Dec 24.

PMID:
22197693
21.

Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo.

Jiang JX, Chen X, Hsu DK, Baghy K, Serizawa N, Scott F, Takada Y, Takada Y, Fukada H, Chen J, Devaraj S, Adamson R, Liu FT, Török NJ.

Am J Physiol Gastrointest Liver Physiol. 2012 Feb 15;302(4):G439-46. doi: 10.1152/ajpgi.00257.2011. Epub 2011 Dec 8.

22.

The bone marrow compartment is modified in the absence of galectin-3.

Brand C, Oliveira FL, Ricon L, Fermino ML, Boldrini LC, Hsu DK, Liu FT, Chammas R, Borojevic R, Farina M, El-Cheikh MC.

Cell Tissue Res. 2011 Dec;346(3):427-37. doi: 10.1007/s00441-011-1276-5. Epub 2011 Nov 27.

23.

LPS-induced galectin-3 oligomerization results in enhancement of neutrophil activation.

Fermino ML, Polli CD, Toledo KA, Liu FT, Hsu DK, Roque-Barreira MC, Pereira-da-Silva G, Bernardes ES, Halbwachs-Mecarelli L.

PLoS One. 2011;6(10):e26004. doi: 10.1371/journal.pone.0026004. Epub 2011 Oct 21.

24.

Ablation of a galectin preferentially expressed in adipocytes increases lipolysis, reduces adiposity, and improves insulin sensitivity in mice.

Yang RY, Yu L, Graham JL, Hsu DK, Lloyd KC, Havel PJ, Liu FT.

Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):18696-701. doi: 10.1073/pnas.1109065108. Epub 2011 Oct 3.

25.

Galectins in regulation of apoptosis.

Liu FT, Yang RY, Saegusa J, Chen HY, Hsu DK.

Adv Exp Med Biol. 2011;705:431-42. doi: 10.1007/978-1-4419-7877-6_22. No abstract available.

PMID:
21618122
26.

Lack of galectin-3 disturbs mesenteric lymph node homeostasis and B cell niches in the course of Schistosoma mansoni infection.

Oliveira FL, Brand C, Paula AA, Arcanjo KD, Hsu DK, Liu FT, Takiya CM, Borojevic R, Chammas R, El-Cheikh MC.

PLoS One. 2011 May 6;6(5):e19216. doi: 10.1371/journal.pone.0019216.

27.

Absence of galectin-3 does not affect the development of experimental tongue carcinomas in mice.

de Faria PR, Chammas R, de Melo TL, Hsu DK, Liu FT, Nonogaki S, Cardoso SV, Loyola AM.

Exp Mol Pathol. 2011 Apr;90(2):189-93. doi: 10.1016/j.yexmp.2010.12.007. Epub 2010 Dec 29.

28.

Galectin-3 preserves renal tubules and modulates extracellular matrix remodeling in progressive fibrosis.

Okamura DM, Pasichnyk K, Lopez-Guisa JM, Collins S, Hsu DK, Liu FT, Eddy AA.

Am J Physiol Renal Physiol. 2011 Jan;300(1):F245-53. doi: 10.1152/ajprenal.00326.2010. Epub 2010 Oct 20.

29.

Fabrication and comparison of PMN-PT single crystal, PZT and PZT-based 1-3 composite ultrasonic transducers for NDE applications.

Kim KB, Hsu DK, Ahn B, Kim YG, Barnard DJ.

Ultrasonics. 2010 Aug;50(8):790-7. doi: 10.1016/j.ultras.2010.04.001. Epub 2010 Apr 24.

PMID:
20580050
30.

Galectin-3 negatively regulates TCR-mediated CD4+ T-cell activation at the immunological synapse.

Chen HY, Fermin A, Vardhana S, Weng IC, Lo KF, Chang EY, Maverakis E, Yang RY, Hsu DK, Dustin ML, Liu FT.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14496-501. doi: 10.1073/pnas.0903497106. Epub 2009 Aug 12.

31.

Galectin-3 regulates peritoneal B1-cell differentiation into plasma cells.

Oliveira FL, Chammas R, Ricon L, Fermino ML, Bernardes ES, Hsu DK, Liu FT, Borojevic R, El-Cheikh MC.

Glycobiology. 2009 Nov;19(11):1248-58. doi: 10.1093/glycob/cwp120. Epub 2009 Aug 20.

PMID:
19696234
32.

Galectin-3 regulates T-cell functions.

Hsu DK, Chen HY, Liu FT.

Immunol Rev. 2009 Jul;230(1):114-27. doi: 10.1111/j.1600-065X.2009.00798.x. Review.

PMID:
19594632
33.

Lack of galectin-3 drives response to Paracoccidioides brasiliensis toward a Th2-biased immunity.

Ruas LP, Bernardes ES, Fermino ML, de Oliveira LL, Hsu DK, Liu FT, Chammas R, Roque-Barreira MC.

PLoS One. 2009;4(2):e4519. doi: 10.1371/journal.pone.0004519. Epub 2009 Feb 20.

34.

Galectin-3 is critical for the development of the allergic inflammatory response in a mouse model of atopic dermatitis.

Saegusa J, Hsu DK, Chen HY, Yu L, Fermin A, Fung MA, Liu FT.

Am J Pathol. 2009 Mar;174(3):922-31. doi: 10.2353/ajpath.2009.080500. Epub 2009 Jan 29.

35.

Targeted disruption of the galectin-3 gene results in decreased susceptibility to multiple low dose streptozotocin-induced diabetes in mice.

Mensah-Brown EP, Al Rabesi Z, Shahin A, Al Shamsi M, Arsenijevic N, Hsu DK, Liu FT, Lukic ML.

Clin Immunol. 2009 Jan;130(1):83-8. doi: 10.1016/j.clim.2008.08.024. Epub 2008 Oct 8.

PMID:
18845486
36.

Endogenous galectin-3 is localized in membrane lipid rafts and regulates migration of dendritic cells.

Hsu DK, Chernyavsky AI, Chen HY, Yu L, Grando SA, Liu FT.

J Invest Dermatol. 2009 Mar;129(3):573-83. doi: 10.1038/jid.2008.276. Epub 2008 Oct 9.

37.

Lack of galectin-3 alters the balance of innate immune cytokines and confers resistance to Rhodococcus equi infection.

Ferraz LC, Bernardes ES, Oliveira AF, Ruas LP, Fermino ML, Soares SG, Loyola AM, Oliver C, Jamur MC, Hsu DK, Liu FT, Chammas R, Roque-Barreira MC.

Eur J Immunol. 2008 Oct;38(10):2762-75. doi: 10.1002/eji.200737986.

38.

Galectin-3 is a negative regulator of lipopolysaccharide-mediated inflammation.

Li Y, Komai-Koma M, Gilchrist DS, Hsu DK, Liu FT, Springall T, Xu D.

J Immunol. 2008 Aug 15;181(4):2781-9.

39.

Nonalcoholic steatohepatitis and hepatocellular carcinoma in galectin-3 knockout mice.

Nakanishi Y, Tsuneyama K, Nomoto K, Fujimoto M, Salunga TL, Nakajima T, Miwa S, Murai Y, Hayashi S, Kato I, Hiraga K, Hsu DK, Liu FT, Takano Y.

Hepatol Res. 2008 Dec;38(12):1241-51. doi: 10.1111/j.1872-034X.2008.00395.x. Epub 2008 Jul 4.

PMID:
18637146
40.

Galectin-3 protects keratinocytes from UVB-induced apoptosis by enhancing AKT activation and suppressing ERK activation.

Saegusa J, Hsu DK, Liu W, Kuwabara I, Kuwabara Y, Yu L, Liu FT.

J Invest Dermatol. 2008 Oct;128(10):2403-11. doi: 10.1038/jid.2008.119. Epub 2008 May 8.

41.

Targeted disruption of the galectin-3 gene results in decreased susceptibility to NNK-induced lung tumorigenesis: an oligonucleotide microarray study.

Abdel-Aziz HO, Murai Y, Takasaki I, Tabuchi Y, Zheng HC, Nomoto K, Takahashi H, Tsuneyama K, Kato I, Hsu DK, Liu FT, Hiraga K, Takano Y.

J Cancer Res Clin Oncol. 2008 Jul;134(7):777-88. doi: 10.1007/s00432-007-0345-3. Epub 2008 Jan 17.

PMID:
18204863
42.

The role of galectin-3 in promotion of the inflammatory response.

Liu FT, Hsu DK.

Drug News Perspect. 2007 Sep;20(7):455-60. Review.

PMID:
17992268
43.

Inhibition of advanced glycation and absence of galectin-3 prevent blood-retinal barrier dysfunction during short-term diabetes.

Canning P, Glenn JV, Hsu DK, Liu FT, Gardiner TA, Stitt AW.

Exp Diabetes Res. 2007;2007:51837.

44.

Role of galectin-3 in prion infections of the CNS.

Mok SW, Riemer C, Madela K, Hsu DK, Liu FT, Gültner S, Heise I, Baier M.

Biochem Biophys Res Commun. 2007 Aug 3;359(3):672-8. Epub 2007 Jun 4.

PMID:
17555713
45.

Kinetics of mobilization and differentiation of lymphohematopoietic cells during experimental murine schistosomiasis in galectin-3 -/- mice.

Oliveira FL, Frazão P, Chammas R, Hsu DK, Liu FT, Borojevic R, Takiya CM, El-Cheikh MC.

J Leukoc Biol. 2007 Aug;82(2):300-10. Epub 2007 Apr 24.

PMID:
17456800
46.

Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection.

Silva-Monteiro E, Reis Lorenzato L, Kenji Nihei O, Junqueira M, Rabinovich GA, Hsu DK, Liu FT, Savino W, Chammas R, Villa-Verde DM.

Am J Pathol. 2007 Feb;170(2):546-56.

47.

Galectin-3 stimulates preadipocyte proliferation and is up-regulated in growing adipose tissue.

Kiwaki K, Novak CM, Hsu DK, Liu FT, Levine JA.

Obesity (Silver Spring). 2007 Jan;15(1):32-9.

48.

Functional capacity of macrophages determines the induction of type 1 diabetes.

Mensah-Brown E, Shahin A, Parekh K, Hakim AA, Shamisi MA, Hsu DK, Lukic ML.

Ann N Y Acad Sci. 2006 Nov;1084:49-57.

PMID:
17151292
49.

Galectins in apoptosis.

Hsu DK, Yang RY, Liu FT.

Methods Enzymol. 2006;417:256-73. Review.

PMID:
17132510
50.

Disrupted galectin-3 causes non-alcoholic fatty liver disease in male mice.

Nomoto K, Tsuneyama K, Abdel Aziz HO, Takahashi H, Murai Y, Cui ZG, Fujimoto M, Kato I, Hiraga K, Hsu DK, Liu FT, Takano Y.

J Pathol. 2006 Dec;210(4):469-77.

PMID:
17029217

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