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End-of-life care following leg amputation in patients with peripheral artery disease or diabetes.

de Mestral C, Hsu AT, Talarico R, Lee DS, Hussain MA, Salata K, Al-Omran M, Tanuseputro P.

Br J Surg. 2019 Oct 14. doi: 10.1002/bjs.11367. [Epub ahead of print]


Impact of an Antibiotic Stewardship Program on the Incidence of Vancomycin-Associated Acute Kidney Injury in Hospitalized Children.

Hsu AJ, Tamma PD.

J Pediatr Pharmacol Ther. 2019 Sep-Oct;24(5):416-420. doi: 10.5863/1551-6776-24.5.416.


Does inpatient palliative care consultation impact outcomes following hospital discharge? A narrative systematic review.

Scott M, Shaver N, Lapenskie J, Isenberg SR, Saunders S, Hsu AT, Tanuseputro P.

Palliat Med. 2019 Oct 4:269216319870649. doi: 10.1177/0269216319870649. [Epub ahead of print]


Bariatric surgery is associated with reduction in non-alcoholic steatohepatitis and hepatocellular carcinoma: A propensity matched analysis.

Kwak M, Mehaffey JH, Hawkins RB, Hsu A, Schirmer B, Hallowell PT.

Am J Surg. 2019 Sep 16. pii: S0002-9610(19)30853-0. doi: 10.1016/j.amjsurg.2019.09.006. [Epub ahead of print]


Sensitive molecular testing methods can demonstrate NSCLC driver mutations in malignant pleural effusion despite non-malignant cytology.

Steinfort DP, Kranz S, Dowers A, Leas L, Dimitriadis V, Pham K, Hsu A, Bozinovski S, Irving LB, Loveland P, Christie M.

Transl Lung Cancer Res. 2019 Aug;8(4):513-518. doi: 10.21037/tlcr.2019.07.05.


Do Geographic Region, Medicaid Status, and Academic Affiliation Affect Access to Care Among Medicaid and Privately Insured Total Hip Arthroplasty Patients?

Almaguer AM, Hsu AR, Pearson JM, McKissack HM, Jones JR, Naranje SM, Shah AB.

J Arthroplasty. 2019 Aug 2. pii: S0883-5403(19)30714-4. doi: 10.1016/j.arth.2019.07.030. [Epub ahead of print]


End-of-life care in individuals with respiratory diseases: a population study comparing the dying experience between those with chronic obstructive pulmonary disease and lung cancer.

Kendzerska T, Nickerson JW, Hsu AT, Gershon AS, Talarico R, Mulpuru S, Pakhale S, Tanuseputro P.

Int J Chron Obstruct Pulmon Dis. 2019 Jul 31;14:1691-1701. doi: 10.2147/COPD.S210916. eCollection 2019.


Young Physicians Section Report.

Hsu A, Council L.

Mo Med. 2019 Jul-Aug;116(4):281. No abstract available.


Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.

LaBranche CC, Henderson R, Hsu A, Behrens S, Chen X, Zhou T, Wiehe K, Saunders KO, Alam SM, Bonsignori M, Borgnia MJ, Sattentau QJ, Eaton A, Greene K, Gao H, Liao HX, Williams WB, Peacock J, Tang H, Perez LG, Edwards RJ, Kepler TB, Korber BT, Kwong PD, Mascola JR, Acharya P, Haynes BF, Montefiori DC.

PLoS Pathog. 2019 Sep 17;15(9):e1008026. doi: 10.1371/journal.ppat.1008026. eCollection 2019 Sep.


Physicians Prescribe More Opioid Than Needed to Treat Pain in Children After Outpatient Urological Procedures: An Observational Cohort Study.

Hunsberger JB, Hsu A, Yaster M, Vozzo PT, Gao S, White ED, Yenokyan G, Vickers B, Monitto CL.

Anesth Analg. 2019 Sep 10. doi: 10.1213/ANE.0000000000004392. [Epub ahead of print]


Treatment of Idiopathic Scoliosis With Vertebral Body Stapling.

Trupia E, Hsu AC, Mueller JD, Matsumoto H, Bodenstein L, Vitale M.

Spine Deform. 2019 Sep;7(5):720-728. doi: 10.1016/j.jspd.2019.01.006.


Prospective Study of a Novel, Radiation-Free, Reduced-Intensity Bone Marrow Transplantation Platform for Primary Immunodeficiency Diseases.

Dimitrova D, Gea-Banacloche J, Steinberg SM, Sadler JL, Hicks SN, Carroll E, Wilder JS, Parta M, Skeffington L, Hughes TE, Blau JE, Broadney MM, Rose JJ, Hsu AP, Fletcher R, Nunes NS, Yan XY, Telford WG, Kapoor V, Cohen JI, Freeman AF, Garabedian E, Holland SM, Lisco A, Malech HL, Notarangelo LD, Sereti I, Shah NN, Uzel G, Zerbe CS, Fowler DH, Gress RE, Kanakry CG, Kanakry JA.

Biol Blood Marrow Transplant. 2019 Sep 4. pii: S1083-8791(19)30558-0. doi: 10.1016/j.bbmt.2019.08.018. [Epub ahead of print]


Synovial fluid cell counts and its role in the diagnosis of paediatric septic arthritis.

Obana KK, Murgai RR, Schur M, Broom AM, Hsu A, Kay RM, Pace JL.

J Child Orthop. 2019 Aug 1;13(4):417-422. doi: 10.1302/1863-2548.13.190022.


Cryo-EM reveals active site coordination within a multienzyme pre-rRNA processing complex.

Pillon MC, Hsu AL, Krahn JM, Williams JG, Goslen KH, Sobhany M, Borgnia MJ, Stanley RE.

Nat Struct Mol Biol. 2019 Sep;26(9):830-839. doi: 10.1038/s41594-019-0289-8. Epub 2019 Sep 5.


Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood.

Peng S, Zaretsky JM, Ng AHC, Chour W, Bethune MT, Choi J, Hsu A, Holman E, Ding X, Guo K, Kim J, Xu AM, Heath JE, Noh WJ, Zhou J, Su Y, Lu Y, McLaughlin J, Cheng D, Witte ON, Baltimore D, Ribas A, Heath JR.

Cell Rep. 2019 Sep 3;28(10):2728-2738.e7. doi: 10.1016/j.celrep.2019.07.106.


Phenotype-Specific Therapeutic Effect of Rhodiola wallichiana var. cholaensis Combined with Dexamethasone on Experimental Murine Asthma and Its Comprehensive Pharmacological Mechanism.

Pang Z, Ran N, Yuan Y, Wang C, Wang G, Lin H, Hsu AC, Liu J, Wang F.

Int J Mol Sci. 2019 Aug 28;20(17). pii: E4216. doi: 10.3390/ijms20174216.


A Stress-Responsive Signaling Network Regulating Pseudohyphal Growth and Ribonucleoprotein Granule Abundance in Saccharomyces cerevisiae.

Mutlu N, Sheidy DT, Hsu A, Jeong HS, Wozniak KJ, Kumar A.

Genetics. 2019 Oct;213(2):705-720. doi: 10.1534/genetics.119.302538. Epub 2019 Aug 27.


Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration.

Hsu AY, Wang D, Liu S, Lu J, Syahirah R, Bennin DA, Huttenlocher A, Umulis DM, Wan J, Deng Q.

Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18561-18570. doi: 10.1073/pnas.1905221116. Epub 2019 Aug 26.


Optimizing the Management of Uncomplicated Gram-Negative Bloodstream Infections in Children: Translating Evidence From Adults Into Pediatric Practice.

Same RG, Hsu AJ, Tamma PD.

J Pediatric Infect Dis Soc. 2019 Aug 22. pii: piz051. doi: 10.1093/jpids/piz051. [Epub ahead of print] No abstract available.


Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel.

Yin Y, Wu M, Hsu AL, Borschel WF, Borgnia MJ, Lander GC, Lee SY.

Nat Commun. 2019 Aug 20;10(1):3740. doi: 10.1038/s41467-019-11733-5.


Optimizing efficiency and safety in external beam radiotherapy using automated plan check (APC) tool and six sigma methodology.

Liu S, Bush KK, Bertini J, Fu Y, Lewis JM, Pham DJ, Yang Y, Niedermayr TR, Skinner L, Xing L, Beadle BM, Hsu A, Kovalchuk N.

J Appl Clin Med Phys. 2019 Aug;20(8):56-64. doi: 10.1002/acm2.12678.


Detection of chemical exchange in methyl groups of macromolecules.

Gill ML, Hsu A, Palmer AG.

J Biomol NMR. 2019 Aug 12. doi: 10.1007/s10858-019-00240-w. [Epub ahead of print]


Physician Availability in Long-term Care and Resident Hospital Transfer: A Retrospective Cohort Study.

Kobewka DM, Kunkel E, Hsu A, Talarico R, Tanuseputro P.

J Am Med Dir Assoc. 2019 Aug 5. pii: S1525-8610(19)30490-6. doi: 10.1016/j.jamda.2019.06.004. [Epub ahead of print]


Repair of Combined Insertional and Midsubstance Achilles Tendon Ruptures.

Hsu AR.

Orthopedics. 2019 Jul 26:1-8. doi: 10.3928/01477447-20190723-07. [Epub ahead of print]


STAT1 Gain-of-Function Mutations Cause High Total STAT1 Levels With Normal Dephosphorylation.

Zimmerman O, Olbrich P, Freeman AF, Rosen LB, Uzel G, Zerbe CS, Rosenzweig SD, Kuehn HS, Holmes KL, Stephany D, Ding L, Sampaio EP, Hsu AP, Holland SM.

Front Immunol. 2019 Jul 10;10:1433. doi: 10.3389/fimmu.2019.01433. eCollection 2019.


Combined genetic disruption of K-Cl cotransporters and Gardos channel KCNN4 rescues erythrocyte dehydration in the SAD mouse model of sickle cell disease.

Shmukler BE, Rivera A, Bhargava P, Nishimura K, Hsu A, Kim EH, Trudel M, Rust MB, Hubner CA, Brugnara C, Alper SL.

Blood Cells Mol Dis. 2019 Nov;79:102346. doi: 10.1016/j.bcmd.2019.102346. Epub 2019 Jul 17.


The Health Impact of Living in a Nursing Home With a Predominantly Different Spoken Language.

Batista R, Prud'homme D, Hsu AT, Guérin E, Bouchard L, Rhodes E, Talarico R, Desaulniers J, Manuel D, Tanuseputro P.

J Am Med Dir Assoc. 2019 Jul 24. pii: S1525-8610(19)30489-X. doi: 10.1016/j.jamda.2019.06.003. [Epub ahead of print] No abstract available.


Fibulin-1c regulates transforming growth factor-β activation in pulmonary tissue fibrosis.

Liu G, Cooley MA, Jarnicki AG, Borghuis T, Nair PM, Tjin G, Hsu AC, Haw TJ, Fricker M, Harrison CL, Jones B, Hansbro NG, Wark PA, Horvat JC, Argraves WS, Oliver BG, Knight DA, Burgess JK, Hansbro PM.

JCI Insight. 2019 Jul 25;5. pii: 124529. doi: 10.1172/jci.insight.124529.


Attitudes and self-reported practices of orthopedic providers regarding prescription opioid use.

Kattail D, Hsu A, Yaster M, Vozzo PT, Gao S, Thompson JM, Roter DL, Laporte D, Henn RF 3rd, Fiadjoe JE, Monitto CL.

J Opioid Manag. 2019 May/Jun;15(3):213-228. doi: 10.5055/jom.2019.0505.


RIPLET, and not TRIM25, is required for endogenous RIG-I-dependent antiviral responses.

Hayman TJ, Hsu AC, Kolesnik TB, Dagley LF, Willemsen J, Tate MD, Baker PJ, Kershaw NJ, Kedzierski L, Webb AI, Wark PA, Kedzierska K, Masters SL, Belz GT, Binder M, Hansbro PM, Nicola NA, Nicholson SE.

Immunol Cell Biol. 2019 Oct;97(9):840-852. doi: 10.1111/imcb.12284. Epub 2019 Aug 19.


Rates of emergency department visits attributable to alcohol use in Ontario from 2003 to 2016: a retrospective population-level study.

Myran DT, Hsu AT, Smith G, Tanuseputro P.

CMAJ. 2019 Jul 22;191(29):E804-E810. doi: 10.1503/cmaj.181575.


Netrin-1 Dampens Hypobaric Hypoxia-Induced Lung Injury in Mice.

Ko CL, Lin JA, Chen KY, Hsu AC, Wu SY, Tai YT, Lin KH, Chung WC, Li MH.

High Alt Med Biol. 2019 Sep;20(3):293-302. doi: 10.1089/ham.2018.0116. Epub 2019 Jul 22.


Probable Interaction Between Warfarin and Inhaled and Oral Administration of Cannabis.

Hsu A, Painter NA.

J Pharm Pract. 2019 Jul 18:897190019854958. doi: 10.1177/0897190019854958. [Epub ahead of print]


Pilot Randomized Controlled Trial of an Exercise Program Requiring Minimal In-person Visits for Youth With Persistent Sport-Related Concussion.

Chrisman SPD, Whitlock KB, Mendoza JA, Burton MS, Somers E, Hsu A, Fay L, Palermo TM, Rivara FP.

Front Neurol. 2019 Jun 17;10:623. doi: 10.3389/fneur.2019.00623. eCollection 2019.


Acute Care Utilization and Place of Death among Patients Discharged from an Inpatient Palliative Care Unit.

Webber C, Hsu AT, Tanuseputro P, Fitzgibbon E, Li C.

J Palliat Med. 2019 Jul 15. doi: 10.1089/jpm.2019.0162. [Epub ahead of print]


Identification and characterization of permissive cells to dengue virus infection in human hematopoietic stem and progenitor cells.

Hsu AY, Ho TC, Lai ML, Tan SS, Chen TY, Lee M, Chien YW, Chen YP, Perng GC.

Transfusion. 2019 Sep;59(9):2938-2951. doi: 10.1111/trf.15416. Epub 2019 Jun 28.


Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production.

Hu M, Schulze KE, Ghildyal R, Henstridge DC, Kolanowski JL, New EJ, Hong Y, Hsu AC, Hansbro PM, Wark PA, Bogoyevitch MA, Jans DA.

Elife. 2019 Jun 27;8. pii: e42448. doi: 10.7554/eLife.42448.


Rapid progression to AML in a patient with germline GATA2 mutation and acquired NRAS Q61K mutation.

McReynolds LJ, Zhang Y, Yang Y, Tang J, Mulé M, Hsu AP, Townsley DM, West RR, Zhu J, Hickstein DD, Holland SM, Calvo KR, Hourigan CS.

Leuk Res Rep. 2019 Jun 10;12:100176. doi: 10.1016/j.lrr.2019.100176. eCollection 2019.


Role of colonoscopy in diagnosis of capecitabine associated ileitis: Two case reports.

Dao AE, Hsu A, Nakshabandi A, Mandaliya R, Nadella S, Sivaraman A, Mattar M, Charabaty A.

World J Gastrointest Endosc. 2019 May 16;11(5):383-388. doi: 10.4253/wjge.v11.i5.383.


Obstruction-Free Survival Following Operative Intervention for Malignant Bowel Obstruction in Appendiceal Cancer.

Baumgartner JM, Marmor R, Hsu A, Veerapong J, Kelly KJ, Lowy AM.

Ann Surg Oncol. 2019 Oct;26(11):3611-3617. doi: 10.1245/s10434-019-07507-4. Epub 2019 Jun 12.


Role of the Innate Cytokine Storm Induced by the Influenza A Virus.

Gu Y, Hsu AC, Pang Z, Pan H, Zuo X, Wang G, Zheng J, Wang F.

Viral Immunol. 2019 Jul/Aug;32(6):244-251. doi: 10.1089/vim.2019.0032. Epub 2019 Jun 12.


Inducible overexpression of zebrafish microRNA-722 suppresses chemotaxis of human neutrophil like cells.

Hsu AY, Liu S, Syahirah R, Brasseale KA, Wan J, Deng Q.

Mol Immunol. 2019 Aug;112:206-214. doi: 10.1016/j.molimm.2019.06.001. Epub 2019 Jun 5.


Lymphocyte-driven regional immunopathology in pneumonitis caused by impaired central immune tolerance.

Ferré EMN, Break TJ, Burbelo PD, Allgäuer M, Kleiner DE, Jin D, Xu Z, Folio LR, Mollura DJ, Swamydas M, Gu W, Hunsberger S, Lee CR, Bondici A, Hoffman KW, Lim JK, Dobbs K, Niemela JE, Fleisher TA, Hsu AP, Snow LN, Darnell DN, Ojaimi S, Cooper MA, Bozzola M, Kleiner GI, Martinez JC, Deterding RR, Kuhns DB, Heller T, Winer KK, Rajan A, Holland SM, Notarangelo LD, Fennelly KP, Olivier KN, Lionakis MS.

Sci Transl Med. 2019 Jun 5;11(495). pii: eaav5597. doi: 10.1126/scitranslmed.aav5597.


Chitinase-like protein YKL-40 correlates with inflammatory phenotypes, anti-asthma responsiveness and future exacerbations.

Liu L, Zhang X, Liu Y, Zhang L, Zheng J, Wang J, Hansbro PM, Wang L, Wang G, Hsu AC.

Respir Res. 2019 May 22;20(1):95. doi: 10.1186/s12931-019-1051-9.


GATA-2-deficient mast cells limit IgE-mediated immediate hypersensitivity reactions in human subjects.

Desai A, Sowerwine K, Liu Y, Lawrence MG, Chovanec J, Hsu AP, O'Connell MP, Kim J, Boris L, Jones N, Wisch L, Eisch RR, Carter MC, Komarow HD, Zerbe C, Milner JD, Maric I, Sun X, Lee CR, Tunc I, Pirooznia M, Stone KD, Holland SM, Metcalfe DD, Lyons JJ.

J Allergy Clin Immunol. 2019 Aug;144(2):613-617.e14. doi: 10.1016/j.jaci.2019.05.007. Epub 2019 May 15. No abstract available.


Symmetry transitions during gating of the TRPV2 ion channel in lipid membranes.

Zubcevic L, Hsu AL, Borgnia MJ, Lee SY.

Elife. 2019 May 15;8. pii: e45779. doi: 10.7554/eLife.45779.


Infraclavicular brachial plexus block in adults: a comprehensive review based on a unified nomenclature system.

Hsu AC, Tai YT, Lin KH, Yao HY, Chiang HL, Ho BY, Yang SF, Lin JA, Ko CL.

J Anesth. 2019 Jun;33(3):463-477. doi: 10.1007/s00540-019-02638-0. Epub 2019 May 10. Review.


Heterozygous activating mutation in RAC2 causes infantile-onset combined immunodeficiency with susceptibility to viral infections.

Sharapova SO, Haapaniemi E, Sakovich IS, Kostyuchenko LV, Donkó A, Dulau-Florea A, Malko O, Bondarenko AV, Stegantseva MV, Leto TL, Uygun V, Karasu GT, Holland SM, Hsu AP, Aleinikova OV.

Clin Immunol. 2019 Aug;205:1-5. doi: 10.1016/j.clim.2019.05.003. Epub 2019 May 7.


Regulatory switch at the cytoplasmic interface controls TRPV channel gating.

Zubcevic L, Borschel WF, Hsu AL, Borgnia MJ, Lee SY.

Elife. 2019 May 9;8. pii: e47746. doi: 10.7554/eLife.47746.


Prolonged Antibiotics for Drains After Spine Injury Instrumentation for Trauma: Not Prophylactic or Necessary.

Skarupa D, Madbak F, Ebler D, Hsu A, Torres MB, Johnson D, Rahmathulla G, Kerwin AJ, Ra J, Shiber J, Crandall M.

World Neurosurg. 2019 Apr 30. pii: S1878-8750(19)31188-X. doi: 10.1016/j.wneu.2019.04.193. [Epub ahead of print]


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