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PRKDC: new biomarker and drug target for checkpoint blockade immunotherapy.

Tan KT, Yeh CN, Chang YC, Cheng JH, Fang WL, Yeh YC, Wang YC, Hsu DS, Wu CE, Lai JI, Chang PM, Chen MH, Lu ML, Chen SJ, Chao Y, Hsiao M, Chen MH.

J Immunother Cancer. 2020 Mar;8(1). pii: e000485. doi: 10.1136/jitc-2019-000485.


Ultrasonography-guided botulinum toxin injection to the cricopharyngeus muscle: a case report and technical notes.

Wang YC, Wu CH, Shyu SG, Hsiao MY, Wang TG.

Med Ultrason. 2019 Nov 8. doi: 10.11152/mu-2097. [Epub ahead of print]


Nonenzymatic function of Aldolase A downregulates miR-145 to promote the Oct4/DUSP4/TRAF4 axis and the acquisition of lung cancer stemness.

Chang YC, Yang YF, Chiou J, Tsai HF, Fang CY, Yang CJ, Chen CL, Hsiao M.

Cell Death Dis. 2020 Mar 18;11(3):195. doi: 10.1038/s41419-020-2387-2.


An unusual presentation of neuropathic pain following cervical spinal cord injury: a case report.

Chang MC, Boudier-Revéret M, Choo YJ, Hsiao MY.

BMC Neurol. 2020 Feb 18;20(1):61. doi: 10.1186/s12883-020-01644-0.


Molecular profiling of gynecologic cancers for treatment and management of disease - demonstrating clinical significance using the AMP/ASCO/CAP guidelines for interpretation and reporting of somatic variants.

Nie Q, Omerza G, Chandok H, Prego M, Hsiao MC, Meyers B, Hesse A, Uvalic J, Soucy M, Bergeron D, Peracchio M, Burns S, Kelly K, Rowe S, Rueter J, Reddi HV.

Cancer Genet. 2020 Apr;242:25-34. doi: 10.1016/j.cancergen.2019.11.008. Epub 2020 Jan 14.


Overexpression of PSAT1 promotes metastasis of lung adenocarcinoma by suppressing the IRF1-IFNγ axis.

Chan YC, Chang YC, Chuang HH, Yang YC, Lin YF, Huang MS, Hsiao M, Yang CJ, Hua KT.

Oncogene. 2020 Mar;39(12):2509-2522. doi: 10.1038/s41388-020-1160-4. Epub 2020 Jan 27.


On Anonymizing Medical Microdata with Large-Scale Missing Values - A Case Study with the FAERS Dataset.

Hsiao MH, Lin WY, Hsu KY, Shen ZX.

Conf Proc IEEE Eng Med Biol Soc. 2019 Jul;2019:6505-6508. doi: 10.1109/EMBC.2019.8857025.


Theranostic nanobubble encapsulating a plasmon-enhanced upconversion hybrid nanosystem for cancer therapy.

Huang WT, Chan MH, Chen X, Hsiao M, Liu RS.

Theranostics. 2020 Jan 1;10(2):782-796. doi: 10.7150/thno.38684. eCollection 2020.


Amplification-driven BCL6-suppressed cytostasis is mediated by transrepression of FOXO3 and post-translational modifications of FOXO3 in urinary bladder urothelial carcinoma.

Wu WR, Lin JT, Pan CT, Chan TC, Liu CL, Wu WJ, Sheu JJ, Yeh BW, Huang SK, Jhung JY, Hsiao MS, Li CF, Shiue YL.

Theranostics. 2020 Jan 1;10(2):707-724. doi: 10.7150/thno.39018. eCollection 2020.


Ovatodiolide Suppresses Oral Cancer Malignancy by Down-Regulating Exosomal Mir-21/STAT3/β-Catenin Cargo and Preventing Oncogenic Transformation of Normal Gingival Fibroblasts.

Chen JH, Wu ATH, Bamodu OA, Yadav VK, Chao TY, Tzeng YM, Mukhopadhyay D, Hsiao M, Lee JC.

Cancers (Basel). 2019 Dec 24;12(1). pii: E56. doi: 10.3390/cancers12010056.


Urolithiasis Is a Risk Factor for Uroseptic Shock and Acute Kidney Injury in Patients With Urinary Tract Infection.

Hsiao CY, Chen TH, Lee YC, Hsiao MC, Hung PH, Chen YY, Wang MC.

Front Med (Lausanne). 2019 Dec 5;6:288. doi: 10.3389/fmed.2019.00288. eCollection 2019.


CD47-SIRPα Signaling Induces Epithelial-Mesenchymal Transition and Cancer Stemness and Links to a Poor Prognosis in Patients with Oral Squamous Cell Carcinoma.

Pai S, Bamodu OA, Lin YK, Lin CS, Chu PY, Chien MH, Wang LS, Hsiao M, Yeh CT, Tsai JT.

Cells. 2019 Dec 17;8(12). pii: E1658. doi: 10.3390/cells8121658.


Molecular profiling of CNS tumors for the treatment and management of disease.

Nie Q, Hsiao MC, Chandok H, Rowe S, Prego M, Meyers B, Omerza G, Hesse A, Uvalic J, Soucy M, Bergeron D, Peracchio M, Burns S, Kelly K, Rueter J, Reddi HV.

J Clin Neurosci. 2020 Jan;71:311-315. doi: 10.1016/j.jocn.2019.11.035. Epub 2019 Dec 16.


Comment on 'Cutaneous innervation of the hand: clinical testing in volunteers shows high intra- and inter-individual variability' (Br J Anaesth 2018; 120: 836-45).

Cheng SH, Chang MC, Boudier-Revéret M, Hsiao MY.

Br J Anaesth. 2020 Feb;124(2):e24-e26. doi: 10.1016/j.bja.2019.11.004. Epub 2019 Dec 6. No abstract available.


FOXD1 and Gal-3 Form a Positive Regulatory Loop to Regulate Lung Cancer Aggressiveness.

Li CH, Chang YC, Hsiao M, Liang SM.

Cancers (Basel). 2019 Nov 28;11(12). pii: E1897. doi: 10.3390/cancers11121897.


The Effectiveness of Pulsed Radiofrequency on Joint Pain: A Narrative Review.

Boudier-Revéret M, Thu AC, Hsiao MY, Shyu SG, Chang MC.

Pain Pract. 2019 Nov 29. doi: 10.1111/papr.12863. [Epub ahead of print] Review.


Mutation Yield of a Custom 212-Gene Next-Generation Sequencing Panel for Solid Tumors: Clinical Experience of the First 260 Cases Tested Using the JAX ActionSeq™ Assay.

Selvam P, Hsiao MC, Omerza G, Bergeron D, Rowe S, Uvalic J, Soucy M, Peracchio M, Burns S, Meyers B, Prego M, Nie Q, Ananda G, Chandok H, Kelly K, Hesse A, Reddi HV.

Mol Diagn Ther. 2020 Feb;24(1):103-111. doi: 10.1007/s40291-019-00435-9.


Multiple Accessory Lower Limb Muscles Identified Using Ultrasonography in An Asymptomatic Individual.

Boudier-Revéret M, Hsiao MY, Michaud J, Chang MC.

Am J Phys Med Rehabil. 2019 Oct 25. doi: 10.1097/PHM.0000000000001318. [Epub ahead of print] No abstract available.


Follistatin-like Protein 1 Inhibits Lung Cancer Metastasis by Preventing Proteolytic Activation of Osteopontin.

Chiou J, Chang YC, Tsai HF, Lin YF, Huang MS, Yang CJ, Hsiao M.

Cancer Res. 2019 Dec 15;79(24):6113-6125. doi: 10.1158/0008-5472.CAN-19-0842. Epub 2019 Oct 25.


High-CLDN4 ESCC cells harbor stem-like properties and indicate for poor concurrent chemoradiation therapy response in esophageal squamous cell carcinoma.

Lin CH, Li HY, Liu YP, Kuo PF, Wang WC, Lin FC, Chang WL, Sheu BS, Wang YC, Hung WC, Cheng HC, Yao YC, Calkins MJ, Hsiao M, Lu PJ.

Ther Adv Med Oncol. 2019 Sep 27;11:1758835919875324. doi: 10.1177/1758835919875324. eCollection 2019.


Implementation of "Treat-all" at adult HIV care and treatment sites in the Global IeDEA Consortium: results from the Site Assessment Survey.

Brazier E, Maruri F, Duda SN, Tymejczyk O, Wester CW, Somi G, Ross J, Freeman A, Cornell M, Poda A, Musick BS, Zhang F, Althoff KN, Mugglin C, Kimmel AD, Yotebieng M, Nash D; IeDEA Consortium.

J Int AIDS Soc. 2019 Jul;22(7):e25331. doi: 10.1002/jia2.25331.


Blockchain Technology: Efficiently Managing Medical Information in the Pain Management Field.

Chang MC, Hsiao MY, Boudier-Revéret M.

Pain Med. 2019 Oct 14. pii: pnz261. doi: 10.1093/pm/pnz261. [Epub ahead of print] No abstract available.


Overexpression of BZW1 is an independent poor prognosis marker and its down-regulation suppresses lung adenocarcinoma metastasis.

Chiou J, Chang YC, Jan YH, Tsai HF, Yang CJ, Huang MS, Yu YL, Hsiao M.

Sci Rep. 2019 Oct 10;9(1):14624. doi: 10.1038/s41598-019-50874-x.


A Novel Multi-Target Small Molecule, LCC-09, Inhibits Stemness and Therapy-Resistant Phenotypes of Glioblastoma Cells by Increasing miR-34a and Deregulating the DRD4/Akt/mTOR Signaling Axis.

Wen YT, Wu AT, Bamodu OA, Wei L, Lin CM, Yen Y, Chao TY, Mukhopadhyay D, Hsiao M, Huang HS.

Cancers (Basel). 2019 Sep 26;11(10). pii: E1442. doi: 10.3390/cancers11101442.


The Development and Applications of a Dual Optical Imaging System for Studying Glioma Stem Cells.

Tai PA, Liu YL, Wen YT, Lin CM, Huynh TT, Hsiao M, Wu ATH, Wei L.

Mol Imaging. 2019 Jan-Dec;18:1536012119870899. doi: 10.1177/1536012119870899.


Enrichment of Aldolase C Correlates with Low Non-Mutated IDH1 Expression and Predicts a Favorable Prognosis in Glioblastomas.

Chang YC, Tsai HF, Huang SP, Chen CL, Hsiao M, Tsai WC.

Cancers (Basel). 2019 Aug 23;11(9). pii: E1238. doi: 10.3390/cancers11091238.


Chemical Radiculitis Induced by an Annular Tear Detected by Gadolinium-Enhanced, but Not in Unenhanced, Magnetic Resonance Imaging.

Chang MC, Boudier-Revéret M, Lee W, Hsiao MY.

Pain Pract. 2020 Jan;20(1):112-113. doi: 10.1111/papr.12828. Epub 2019 Aug 30. No abstract available.


Graphitic carbon nitride-based nanocomposites and their biological applications: a review.

Chan MH, Liu RS, Hsiao M.

Nanoscale. 2019 Aug 15;11(32):14993-15003. doi: 10.1039/c9nr04568f. Review.


Therapeutic Targeting of Aldolase A Interactions Inhibits Lung Cancer Metastasis and Prolongs Survival.

Chang YC, Chiou J, Yang YF, Su CY, Lin YF, Yang CN, Lu PJ, Huang MS, Yang CJ, Hsiao M.

Cancer Res. 2019 Sep 15;79(18):4754-4766. doi: 10.1158/0008-5472.CAN-18-4080. Epub 2019 Jul 29.


The Effect of the Repression of Oxidative Stress on Tenocyte Differentiation: A Preliminary Study of a Rat Cell Model Using a Novel Differential Tensile Strain Bioreactor.

Hsiao MY, Lin PC, Liao WH, Chen WS, Hsu CH, He CK, Wu YW, Gefen A, Iafisco M, Liu L, Lin FH.

Int J Mol Sci. 2019 Jul 12;20(14). pii: E3437. doi: 10.3390/ijms20143437.


Ultrasound-Guided Three-in-One Trigger Point Injection for Muscles of the Posterior Axillary Fold.

Chang MC, Boudier-Revéret M, Hsiao MY.

Pain Pract. 2020 Jan;20(1):110-111. doi: 10.1111/papr.12819. Epub 2019 Sep 13. No abstract available.


Autophagosome accumulation-mediated ATP energy deprivation induced by penfluridol triggers nonapoptotic cell death of lung cancer via activating unfolded protein response.

Hung WY, Chang JH, Cheng Y, Cheng GZ, Huang HC, Hsiao M, Chung CL, Lee WJ, Chien MH.

Cell Death Dis. 2019 Jul 15;10(8):538. doi: 10.1038/s41419-019-1785-9.


Development of upconversion nanoparticle-conjugated indium phosphide quantum dot for matrix metalloproteinase-2 cancer transformation sensing.

Chan MH, Lai CY, Chan YC, Hsiao M, Chung RJ, Chen X, Liu RS.

Nanomedicine (Lond). 2019 Jul;14(14):1791-1804. doi: 10.2217/nnm-2018-0524. Epub 2019 Jul 15.


Ambient particulate matter attenuates Sirtuin1 and augments SREBP1-PIR axis to induce human pulmonary fibroblast inflammation: molecular mechanism of microenvironment associated with COPD.

Tien CP, Chen CH, Lin WY, Liu CS, Liu KJ, Hsiao M, Chang YC, Hung SC.

Aging (Albany NY). 2019 Jul 12;11(13):4654-4671. doi: 10.18632/aging.102077.


Down-regulation of ATF1 leads to early neuroectoderm differentiation of human embryonic stem cells by increasing the expression level of SOX2.

Yang SC, Liu JJ, Wang CK, Lin YT, Tsai SY, Chen WJ, Huang WK, Tu PA, Lin YC, Chang CF, Cheng CL, Lin H, Lai CY, Lin CY, Lee YH, Chiu YC, Hsu CC, Hsu SC, Hsiao M, Schuyler SC, Lu FL, Lu J.

FASEB J. 2019 Sep;33(9):10577-10592. doi: 10.1096/fj.201800220RR. Epub 2019 Jun 26.


Comparison of cofilin‑1 and Twist‑1 protein expression in human non‑small cell lung cancer tissues.

Chang CY, Chang SL, Leu JD, Chang YC, Hsiao M, Lin LT, Lin HN, Lee YJ.

Oncol Rep. 2019 Aug;42(2):805-816. doi: 10.3892/or.2019.7193. Epub 2019 Jun 10.


Increased risk of 100-day and 1-year infection-related mortality and complications in haploidentical stem cell transplantation.

Chang J, Hsiao M, Blodget E, Akhtari M.

J Blood Med. 2019 May 15;10:135-143. doi: 10.2147/JBM.S201073. eCollection 2019.


HIV Infection: Its Impact on Patients with Appendicitis in Botswana.

Bedada AG, Hsiao M, Azzie G.

World J Surg. 2019 Sep;43(9):2131-2136. doi: 10.1007/s00268-019-05040-9.


AKR1C1 controls cisplatin-resistance in head and neck squamous cell carcinoma through cross-talk with the STAT1/3 signaling pathway.

Chang WM, Chang YC, Yang YC, Lin SK, Chang PM, Hsiao M.

J Exp Clin Cancer Res. 2019 Jun 10;38(1):245. doi: 10.1186/s13046-019-1256-2.


Targeting the SPOCK1-snail/slug axis-mediated epithelial-to-mesenchymal transition by apigenin contributes to repression of prostate cancer metastasis.

Chien MH, Lin YW, Wen YC, Yang YC, Hsiao M, Chang JL, Huang HC, Lee WJ.

J Exp Clin Cancer Res. 2019 Jun 10;38(1):246. doi: 10.1186/s13046-019-1247-3.


Ovatodiolide inhibits the oncogenicity and cancer stem cell-like phenotype of glioblastoma cells, as well as potentiate the anticancer effect of temozolomide.

Su YK, Bamodu OA, Tzeng YM, Hsiao M, Yeh CT, Lin CM.

Phytomedicine. 2019 Aug;61:152840. doi: 10.1016/j.phymed.2019.152840. Epub 2019 Jan 19.


Development of an Enzyme-Linked Immunosorbent Assay for Rapid Detection of Dengue Virus (DENV) NS1 and Differentiation of DENV Serotypes during Early Infection.

Lai SC, Huang YY, Shu PY, Chang SF, Hsieh PS, Wey JJ, Tsai MH, Ben RJ, Hsu YM, Fang YC, Hsiao ML, Lin CC.

J Clin Microbiol. 2019 Jun 25;57(7). pii: e00221-19. doi: 10.1128/JCM.00221-19. Print 2019 Jul.


Bidentate chelating ligands as effective passivating materials for perovskite light-emitting diodes.

Hsiao MC, Chien PC, Jhuang LS, Chen FC.

Phys Chem Chem Phys. 2019 Apr 21;21(15):7867-7873. doi: 10.1039/c8cp07000h. Epub 2019 Mar 27.


Drug-loaded hyaluronic acid hydrogel as a sustained-release regimen with dual effects in early intervention of tendinopathy.

Hsiao MY, Lin AC, Liao WH, Wang TG, Hsu CH, Chen WS, Lin FH.

Sci Rep. 2019 Mar 18;9(1):4784. doi: 10.1038/s41598-019-41410-y.


In Operando Observation of Neuropeptide Capture and Release on Graphene Field-Effect Transistor Biosensors with Picomolar Sensitivity.

Kim S, Xing L, Islam AE, Hsiao MS, Ngo Y, Pavlyuk OM, Martineau RL, Hampton CM, Crasto C, Slocik J, Kadakia MP, Hagen JA, Kelley-Loughnane N, Naik RR, Drummy LF.

ACS Appl Mater Interfaces. 2019 Apr 17;11(15):13927-13934. doi: 10.1021/acsami.8b20498. Epub 2019 Apr 5.


Ghrelin Upregulates Oncogenic Aurora A to Promote Renal Cell Carcinoma Invasion.

Lin TC, Yeh YM, Fan WL, Chang YC, Lin WM, Yang TY, Hsiao M.

Cancers (Basel). 2019 Mar 4;11(3). pii: E303. doi: 10.3390/cancers11030303.


Cumulative Electroconvulsive Therapy-Associated Severe Hyperammonemic Encephalopathy: A Case Report.

Hsiao MH, Yeh TC, Ku SC, Tseng YT, Liang CS.

Am J Ther. 2019 Nov/Dec;26(6):e784-e786. doi: 10.1097/MJT.0000000000000960. No abstract available.


Signaling pathway of globo-series glycosphingolipids and β1,3-galactosyltransferase V (β3GalT5) in breast cancer.

Chuang PK, Hsiao M, Hsu TL, Chang CF, Wu CY, Chen BR, Huang HW, Liao KS, Chen CC, Chen CL, Yang SM, Kuo CW, Chen P, Chiu PT, Chen IJ, Lai JS, Yu CT, Wong CH.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3518-3523. doi: 10.1073/pnas.1816946116. Epub 2019 Feb 11.

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