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Items: 32

1.

Nitric oxide-releasing polyacrylonitrile disperses biofilms formed by wound-relevant pathogenic bacteria.

Craven M, Kasper SH, Canfield MJ, Diaz-Morales RR, Hrabie JA, Cady NC, Strickland AD.

J Appl Microbiol. 2016 Apr;120(4):1085-99. doi: 10.1111/jam.13059. Epub 2016 Mar 1.

PMID:
26784529
2.

Aminolysis of an N-diazeniumdiolated amidine as an approach to diazeniumdiolated ammonia.

Biswas D, Hrabie JA, Saavedra JE, Cao Z, Keefer LK, Ivanic J, Holland RJ.

J Org Chem. 2014 May 16;79(10):4512-6. doi: 10.1021/jo500551n. Epub 2014 May 5.

3.

Nitric oxide delivery via a permeable balloon catheter inhibits neointimal growth after arterial injury.

Havelka GE, Moreira ES, Rodriguez MP, Tsihlis ND, Wang Z, Martínez J, Hrabie JA, Kiefer LK, Kibbe MR.

J Surg Res. 2013 Mar;180(1):35-42. doi: 10.1016/j.jss.2012.10.048. Epub 2012 Nov 10.

4.

Nitrogen-bound diazeniumdiolated amidines.

Biswas D, Deschamps JR, Keefer LK, Hrabie JA.

Chem Commun (Camb). 2010 Aug 21;46(31):5799-801. doi: 10.1039/c0cc00849d. Epub 2010 Jun 30.

PMID:
20589293
5.

Insulin enhances the effect of nitric oxide at inhibiting neointimal hyperplasia in a rat model of type 1 diabetes.

Varu VN, Ahanchi SS, Hogg ME, Bhikhapurwala HA, Chen A, Popowich DA, Vavra AK, Martinez J, Jiang Q, Saavedra JE, Hrabie JA, Keefer LK, Kibbe MR.

Am J Physiol Heart Circ Physiol. 2010 Sep;299(3):H772-9. doi: 10.1152/ajpheart.01234.2009. Epub 2010 Jun 18.

6.

Heightened efficacy of nitric oxide-based therapies in type II diabetes mellitus and metabolic syndrome.

Ahanchi SS, Varu VN, Tsihlis ND, Martinez J, Pearce CG, Kapadia MR, Jiang Q, Saavedra JE, Keefer LK, Hrabie JA, Kibbe MR.

Am J Physiol Heart Circ Physiol. 2008 Dec;295(6):H2388-98. doi: 10.1152/ajpheart.00185.2008. Epub 2008 Oct 17.

7.

Nitric oxide reacts with methoxide.

Derosa F, Keefer LK, Hrabie JA.

J Org Chem. 2008 Feb 1;73(3):1139-42. doi: 10.1021/jo7020423. Epub 2008 Jan 10.

PMID:
18184006
8.

Nitric oxide and nanotechnology: a novel approach to inhibit neointimal hyperplasia.

Kapadia MR, Chow LW, Tsihlis ND, Ahanchi SS, Eng JW, Murar J, Martinez J, Popowich DA, Jiang Q, Hrabie JA, Saavedra JE, Keefer LK, Hulvat JF, Stupp SI, Kibbe MR.

J Vasc Surg. 2008 Jan;47(1):173-82. doi: 10.1016/j.jvs.2007.09.005.

9.

Diazeniumdiolate reactivity in model membrane systems.

Dinh BT, Price SE, Majul A, El-Hajj M, Morozov V, Hrabie JA, Davies KM.

Nitric Oxide. 2008 Mar;18(2):113-21. Epub 2007 Nov 21.

10.

Beneficial effect of a short-acting NO donor for the prevention of neointimal hyperplasia.

Pearce CG, Najjar SF, Kapadia MR, Murar J, Eng J, Lyle B, Aalami OO, Jiang Q, Hrabie JA, Saavedra JE, Keefer LK, Kibbe MR.

Free Radic Biol Med. 2008 Jan 1;44(1):73-81. Epub 2007 Sep 25.

11.

Nitric oxide-releasing fabrics and other acrylonitrile-based diazeniumdiolates.

DeRosa F, Kibbe MR, Najjar SF, Citro ML, Keefer LK, Hrabie JA.

J Am Chem Soc. 2007 Apr 4;129(13):3786-7. Epub 2007 Mar 8. No abstract available.

PMID:
17343382
12.

Nitric oxide releasing polyurethanes with covalently linked diazeniumdiolated secondary amines.

Reynolds MM, Hrabie JA, Oh BK, Politis JK, Citro ML, Keefer LK, Meyerhoff ME.

Biomacromolecules. 2006 Mar;7(3):987-94.

PMID:
16529441
13.

Carbon-bound diazeniumdiolates from the reaction of nitric oxide with amidines.

Hrabie JA, Citro ML, Chmurny GN, Keefer LK.

J Org Chem. 2005 Sep 16;70(19):7647-53.

PMID:
16149795
14.

Effect of hydrophobic structure on the catalysis of nitric oxide release from zwitterionic diazeniumdiolates in surfactant and liposome media.

Dinh B, Dove K, Jappar D, Hrabie JA, Davies KM.

Nitric Oxide. 2005 Nov;13(3):204-9. Epub 2005 Aug 24.

PMID:
16122951
15.

Mechanistic insight into exclusive nitric oxide recovery from a carbon-bound diazeniumdiolate.

Arnold EV, Citro ML, Saavedra EA, Davies KM, Keefer LK, Hrabie JA.

Nitric Oxide. 2002 Sep;7(2):103-8.

PMID:
12223179
16.

Augmentation of intrapericardial nitric oxide level by a prolonged-release nitric oxide donor reduces luminal narrowing after porcine coronary angioplasty.

Baek SH, Hrabie JA, Keefer LK, Hou D, Fineberg N, Rhoades R, March KL.

Circulation. 2002 Jun 11;105(23):2779-84.

PMID:
12057994
17.

A nitric oxide-releasing polydiazeniumdiolate derived from acetonitrile.

Arnold EV, Citro ML, Keefer LK, Hrabie JA.

Org Lett. 2002 Apr 18;4(8):1323-5.

PMID:
11950353
18.

Chemistry of the nitric oxide-releasing diazeniumdiolate ("nitrosohydroxylamine") functional group and its oxygen-substituted derivatives.

Hrabie JA, Keefer LK.

Chem Rev. 2002 Apr;102(4):1135-54. Review. No abstract available.

PMID:
11942789
19.

Qualitative thin-layer and high-performance liquid chromatographic analysis of 1-substituted diazen-1-ium-1,2-diolates on aminopropyl-bonded silica gel.

Fitzhugh AL, Anadu NO, Waterhouse DJ, Hrabie JA, Saavedra JE, Keefer LK.

Anal Biochem. 2002 Feb 1;301(1):97-102.

PMID:
11811972
20.

Analysis of vasodilator responses to novel nitric oxide donors in the hindquarters vascular bed of the cat.

Bivalacqua TJ, Champion HC, De Witt BJ, Saavedra JE, Hrabie JA, Keefer LK, Kadowitz PJ.

J Cardiovasc Pharmacol. 2001 Jul;38(1):120-9.

PMID:
11444495
21.

Reaction of nitric oxide at the beta-carbon of enamines. A new method of preparing compounds containing the diazeniumdiolate functional group.

Hrabie JA, Arnold EV, Citro ML, George C, Keefer LK.

J Org Chem. 2000 Sep 8;65(18):5745-51.

PMID:
10970319
22.

Conversion of proteins to diazeniumdiolate-based nitric oxide donors.

Hrabie JA, Saavedra JE, Roller PP, Southan GJ, Keefer LK.

Bioconjug Chem. 1999 Sep-Oct;10(5):838-42.

PMID:
10502351
23.

Induction of penile erection by intracavernosal and transurethral administration of novel nitric oxide donors in the cat.

Champion HC, Bivalacqua TJ, Wang R, Kadowitz PJ, Keefer LK, Saavedra JE, Hrabie JA, Doherty PC, Hellstrom WJ.

J Urol. 1999 Jun;161(6):2013-9.

PMID:
10332492
24.

Pharmacokinetics and consistency of pericardial delivery directed to coronary arteries: direct comparison with endoluminal delivery.

Stoll HP, Carlson K, Keefer LK, Hrabie JA, March KL.

Clin Cardiol. 1999 Jan;22(1 Suppl 1):I10-6.

25.

Nitric oxide-releasing polymers containing the [N(O)NO]- group.

Smith DJ, Chakravarthy D, Pulfer S, Simmons ML, Hrabie JA, Citro ML, Saavedra JE, Davies KM, Hutsell TC, Mooradian DL, Hanson SR, Keefer LK.

J Med Chem. 1996 Mar 1;39(5):1148-56.

PMID:
8676352
26.

Nitric oxide/nucleophile complexes inhibit the in vitro proliferation of A375 melanoma cells via nitric oxide release.

Maragos CM, Wang JM, Hrabie JA, Oppenheim JJ, Keefer LK.

Cancer Res. 1993 Feb 1;53(3):564-8.

28.

Complexes of .NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects.

Maragos CM, Morley D, Wink DA, Dunams TM, Saavedra JE, Hoffman A, Bove AA, Isaac L, Hrabie JA, Keefer LK.

J Med Chem. 1991 Nov;34(11):3242-7.

PMID:
1956043
29.

Stereoselectivity in the microsomal conversion of N-nitrosodimethylamine to formaldehyde.

Keefer LK, Kroeger-Koepke MB, Ishizaki H, Michejda CJ, Saavedra JE, Hrabie JA, Yang CS, Roller PP.

Chem Res Toxicol. 1990 Nov-Dec;3(6):540-4.

PMID:
2103325
30.

Deuterium isotope effect on the toxicokinetics of monomethylamine in the rat.

Streeter AJ, Nims RW, Sheffels PR, Hrabie JA, Ohannesian L, Heur YH, Mico BA, Keefer LK.

Drug Metab Dispos. 1990 Jul-Aug;18(4):447-52.

PMID:
1976066
31.

Sex differences in the single-dose toxicokinetics of N-nitrosomethyl(2-hydroxyethyl)amine in the rat.

Streeter AJ, Nims RW, Hrabie JA, Heur YH, Keefer LK.

Cancer Res. 1989 Apr 1;49(7):1783-9.

32.

Deuterium isotope effect on denitrosation and demethylation of N-nitrosodimethylamine by rat liver microsomes.

Wade D, Yang CS, Metral CJ, Roman JM, Hrabie JA, Riggs CW, Anjo T, Keefer LK, Mico BA.

Cancer Res. 1987 Jul 1;47(13):3373-7.

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