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Items: 30


Antibodies specifically targeting a locally misfolded region of tumor associated EGFR.

Garrett TP, Burgess AW, Gan HK, Luwor RB, Cartwright G, Walker F, Orchard SG, Clayton AH, Nice EC, Rothacker J, Catimel B, Cavenee WK, Old LJ, Stockert E, Ritter G, Adams TE, Hoyne PA, Wittrup D, Chao G, Cochran JR, Luo C, Lou M, Huyton T, Xu Y, Fairlie WD, Yao S, Scott AM, Johns TG.

Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5082-7. doi: 10.1073/pnas.0811559106. Epub 2009 Mar 16.


Expression, purification and characterization of recombinant phospholipase B from Moraxella bovis with anomalous electrophoretic behavior.

Shiell BJ, Tachedjian M, Bruce K, Beddome G, Farn JL, Hoyne PA, Michalski WP.

Protein Expr Purif. 2007 Oct;55(2):262-72. Epub 2007 Jul 13.


Structure of the insulin receptor ectodomain reveals a folded-over conformation.

McKern NM, Lawrence MC, Streltsov VA, Lou MZ, Adams TE, Lovrecz GO, Elleman TC, Richards KM, Bentley JD, Pilling PA, Hoyne PA, Cartledge KA, Pham TM, Lewis JL, Sankovich SE, Stoichevska V, Da Silva E, Robinson CP, Frenkel MJ, Sparrow LG, Fernley RT, Epa VC, Ward CW.

Nature. 2006 Sep 14;443(7108):218-21. Epub 2006 Sep 6.


The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity.

Lou M, Garrett TP, McKern NM, Hoyne PA, Epa VC, Bentley JD, Lovrecz GO, Cosgrove LJ, Frenkel MJ, Ward CW.

Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12429-34. Epub 2006 Aug 7.


Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor.

Johns TG, Adams TE, Cochran JR, Hall NE, Hoyne PA, Olsen MJ, Kim YS, Rothacker J, Nice EC, Walker F, Ritter G, Jungbluth AA, Old LJ, Ward CW, Burgess AW, Wittrup KD, Scott AM.

J Biol Chem. 2004 Jul 16;279(29):30375-84. Epub 2004 Apr 9.


CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor.

Walker F, Orchard SG, Jorissen RN, Hall NE, Zhang HH, Hoyne PA, Adams TE, Johns TG, Ward C, Garrett TP, Zhu HJ, Nerrie M, Scott AM, Nice EC, Burgess AW.

J Biol Chem. 2004 May 21;279(21):22387-98. Epub 2004 Mar 11.


Crystal structure of a truncated epidermal growth factor receptor extracellular domain bound to transforming growth factor alpha.

Garrett TP, McKern NM, Lou M, Elleman TC, Adams TE, Lovrecz GO, Zhu HJ, Walker F, Frenkel MJ, Hoyne PA, Jorissen RN, Nice EC, Burgess AW, Ward CW.

Cell. 2002 Sep 20;110(6):763-73.


Molecular characterization of a secreted enzyme with phospholipase B activity from Moraxella bovis.

Farn JL, Strugnell RA, Hoyne PA, Michalski WP, Tennent JM.

J Bacteriol. 2001 Nov;183(22):6717-20.


Identification of a determinant of epidermal growth factor receptor ligand-binding specificity using a truncated, high-affinity form of the ectodomain.

Elleman TC, Domagala T, McKern NM, Nerrie M, Lönnqvist B, Adams TE, Lewis J, Lovrecz GO, Hoyne PA, Richards KM, Howlett GJ, Rothacker J, Jorissen RN, Lou M, Garrett TP, Burgess AW, Nice EC, Ward CW.

Biochemistry. 2001 Jul 31;40(30):8930-9.


The three dimensional structure of the type I insulin-like growth factor receptor.

Ward CW, Garrett TP, McKern NM, Lou M, Cosgrove LJ, Sparrow LG, Frenkel MJ, Hoyne PA, Elleman TC, Adams TE, Lovrecz GO, Lawrence LJ, Tulloch PA.

Mol Pathol. 2001 Jun;54(3):125-32. Review.


High affinity insulin binding by soluble insulin receptor extracellular domain fused to a leucine zipper.

Hoyne PA, Cosgrove LJ, McKern NM, Bentley JD, Ivancic N, Elleman TC, Ward CW.

FEBS Lett. 2000 Aug 11;479(1-2):15-8.


Mutational analysis of the N-linked glycosylation sites of the human insulin receptor.

Elleman TC, Frenkel MJ, Hoyne PA, McKern NM, Cosgrove L, Hewish DR, Jachno KM, Bentley JD, Sankovich SE, Ward CW.

Biochem J. 2000 May 1;347 Pt 3:771-9.


Properties of an insulin receptor with an IGF-1 receptor loop exchange in the cysteine-rich region.

Hoyne PA, Elleman TC, Adams TE, Richards KM, Ward CW.

FEBS Lett. 2000 Mar 3;469(1):57-60.


A Moraxella bovis pili vaccine produced by recombinant DNA technology for the prevention of infectious bovine keratoconjunctivitis.

Lepper AW, Elleman TC, Hoyne PA, Lehrbach PR, Atwell JL, Schwartzkoff CL, Egerton JR, Tennent JM.

Vet Microbiol. 1993 Jul;36(1-2):175-83.


The effects of antigenic competition on the efficacy of multivalent footrot vaccines.

Schwartzkoff CL, Egerton JR, Stewart DJ, Lehrbach PR, Elleman TC, Hoyne PA.

Aust Vet J. 1993 Apr;70(4):123-6.


Production of Neisseria gonorrhoeae pili (fimbriae) in Pseudomonas aeruginosa.

Hoyne PA, Haas R, Meyer TF, Davies JK, Elleman TC.

J Bacteriol. 1992 Nov;174(22):7321-7.


Cross-protective immunity and the serological classification system for Bacteroides nodosus.

Stewart DJ, Vaughan JA, Elleman TC, Hoyne PA, Burns KJ, Dufty JH.

Aust Vet J. 1991 Feb;68(2):50-3.


Pilins from the B serogroup of Bacteroides nodosus: characterization, expression, and cross-protection.

Elleman TC, Stewart DJ, Finney KG, Hoyne PA, Ward CW.

Infect Immun. 1990 Jun;58(6):1545-51.


Sequence of pilin from Bacteroides nodosus 351 (Serogroup H) and implications for serogroup classification.

Hoyne PA, Elleman TC, McKern NM, Stewart DJ.

J Gen Microbiol. 1989 May;135(5):1113-22.


Expression of pili from Bacteroides nodosus in Pseudomonas aeruginosa.

Elleman TC, Hoyne PA, Stewart DJ, McKern NM, Peterson JE.

J Bacteriol. 1986 Nov;168(2):574-80.


Nucleotide sequence of the gene encoding the two-subunit pilin of Bacteroides nodosus 265.

Elleman TC, Hoyne PA, McKern NM, Stewart DJ.

J Bacteriol. 1986 Jul;167(1):243-50.


Expression of the pilin gene from Bacteroides nodosus in Escherichia coli.

Elleman TC, Hoyne PA, Emery DL, Stewart DJ, Clark BL.

Infect Immun. 1986 Jan;51(1):187-92.


Isolation of the gene encoding pilin of Bacteroides nodosus (strain 198), the causal organism of ovine footrot.

Elleman TC, Hoyne PA, Emery DL, Stewart DJ, Clark BL.

FEBS Lett. 1984 Jul 23;173(1):103-7.


Nucleotide sequence of the gene encoding the serotype-specific glycoprotein of UK bovine rotavirus.

Elleman TC, Hoyne PA, Dyall-Smith ML, Holmes IH, Azad AA.

Nucleic Acids Res. 1983 Jul 25;11(14):4689-701.


Cloning and sequence of UK bovine rotavirus gene segment 7: marked sequence homology with simian rotavirus gene segment 8.

Dyall-Smith ML, Elleman TC, Hoyne PA, Holmes IH, Azad AA.

Nucleic Acids Res. 1983 May 25;11(10):3351-62.

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