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Pulmonary Function Testing in Animals.

Hoyle GW, Schlueter CF, Musah S.

Methods Mol Biol. 2019;1894:323-330. doi: 10.1007/978-1-4939-8916-4_19.


Chronic + binge alcohol exposure promotes inflammation and alters airway mechanics in the lung.

Poole LG, Beier JI, Torres-Gonzales E, Schlueter CF, Hudson SV, Artis A, Warner NL, Nguyen-Ho CT, Dolin CE, Ritzenthaler JD, Hoyle GW, Roman J, Arteel GE.

Alcohol. 2019 Nov;80:53-63. doi: 10.1016/j.alcohol.2018.10.008. Epub 2018 Nov 14.


Inhibition of chlorine-induced airway fibrosis by budesonide.

Musah S, Chen J, Schlueter C, Humphrey DM Jr, Stocke K, Hoyle MI, Hoyle GW.

Toxicol Appl Pharmacol. 2019 Jan 15;363:11-21. doi: 10.1016/j.taap.2018.08.024. Epub 2018 Sep 3.


An Official American Thoracic Society Workshop Report: Chemical Inhalational Disasters. Biology of Lung Injury, Development of Novel Therapeutics, and Medical Preparedness.

Summerhill EM, Hoyle GW, Jordt SE, Jugg BJ, Martin JG, Matalon S, Patterson SE, Prezant DJ, Sciuto AM, Svendsen ER, White CW, Veress LA; ATS Terrorism and Inhalational Disasters Section of the Environmental, Occupational, and Population Health Assembly.

Ann Am Thorac Soc. 2017 Jun;14(6):1060-1072. doi: 10.1513/AnnalsATS.201704-297WS.


Acute lung injury and persistent small airway disease in a rabbit model of chlorine inhalation.

Musah S, Schlueter CF, Humphrey DM Jr, Powell KS, Roberts AM, Hoyle GW.

Toxicol Appl Pharmacol. 2017 Jan 15;315:1-11. doi: 10.1016/j.taap.2016.11.017. Epub 2016 Nov 30.


Diabetic Microvascular Disease and Pulmonary Fibrosis: The Contribution of Platelets and Systemic Inflammation.

Jagadapillai R, Rane MJ, Lin X, Roberts AM, Hoyle GW, Cai L, Gozal E.

Int J Mol Sci. 2016 Nov 8;17(11). pii: E1853. Review.


Role of TRPA1 in acute cardiopulmonary toxicity of inhaled acrolein.

Conklin DJ, Haberzettl P, Jagatheesan G, Kong M, Hoyle GW.

Toxicol Appl Pharmacol. 2017 Jun 1;324:61-72. doi: 10.1016/j.taap.2016.08.028. Epub 2016 Aug 31.


Persistent effects of chlorine inhalation on respiratory health.

Hoyle GW, Svendsen ER.

Ann N Y Acad Sci. 2016 Aug;1378(1):33-40. doi: 10.1111/nyas.13139. Epub 2016 Jul 6. Review.


Development and assessment of countermeasure formulations for treatment of lung injury induced by chlorine inhalation.

Hoyle GW, Chen J, Schlueter CF, Mo Y, Humphrey DM Jr, Rawson G, Niño JA, Carson KH.

Toxicol Appl Pharmacol. 2016 May 1;298:9-18. doi: 10.1016/j.taap.2016.03.001. Epub 2016 Mar 4.


Seed germination strategies: an evolutionary trajectory independent of vegetative functional traits.

Hoyle GL, Steadman KJ, Good RB, McIntosh EJ, Galea LM, Nicotra AB.

Front Plant Sci. 2015 Oct 12;6:731. doi: 10.3389/fpls.2015.00731. eCollection 2015.


Crystalline silica-induced leukotriene B4-dependent inflammation promotes lung tumour growth.

Satpathy SR, Jala VR, Bodduluri SR, Krishnan E, Hegde B, Hoyle GW, Fraig M, Luster AD, Haribabu B.

Nat Commun. 2015 Apr 29;6:7064. doi: 10.1038/ncomms8064.


Adaptive plasticity and epigenetic variation in response to warming in an Alpine plant.

Nicotra AB, Segal DL, Hoyle GL, Schrey AW, Verhoeven KJ, Richards CL.

Ecol Evol. 2015 Feb;5(3):634-47. doi: 10.1002/ece3.1329. Epub 2015 Jan 13.


Abnormal epithelial structure and chronic lung inflammation after repair of chlorine-induced airway injury.

Mo Y, Chen J, Humphrey DM Jr, Fodah RA, Warawa JM, Hoyle GW.

Am J Physiol Lung Cell Mol Physiol. 2015 Jan 15;308(2):L168-78. doi: 10.1152/ajplung.00226.2014. Epub 2014 Nov 14.


Prognosis of hyponatremia in elderly patients with fragility fractures.

Cumming K, McKenzie S, Hoyle GE, Hutchison JD, Soiza RL.

J Clin Med Res. 2015 Jan;7(1):45-51. doi: 10.14740/jocmr1984w. Epub 2014 Oct 16.


Bioelectrical impedance analysis is more accurate than clinical examination in determining the volaemic status of elderly patients with fragility fracture and hyponatraemia.

Cumming K, Hoyle GE, Hutchison JD, Soiza RL.

J Nutr Health Aging. 2014;18(8):744-50. doi: 10.1007/s12603-014-0446-z.


Prevalence, incidence and etiology of hyponatremia in elderly patients with fragility fractures.

Cumming K, Hoyle GE, Hutchison JD, Soiza RL.

PLoS One. 2014 Feb 5;9(2):e88272. doi: 10.1371/journal.pone.0088272. eCollection 2014.


Effects of reduced winter duration on seed dormancy and germination in six populations of the alpine herb Aciphyllya glacialis (Apiaceae).

Hoyle GL, Cordiner H, Good RB, Nicotra AB.

Conserv Physiol. 2014 May 30;2(1):cou015. doi: 10.1093/conphys/cou015. eCollection 2014.


Inhibition of chlorine-induced pulmonary inflammation and edema by mometasone and budesonide.

Chen J, Mo Y, Schlueter CF, Hoyle GW.

Toxicol Appl Pharmacol. 2013 Oct 15;272(2):408-13. doi: 10.1016/j.taap.2013.06.009. Epub 2013 Jun 22.


Soil warming increases plant species richness but decreases germination from the alpine soil seed bank.

Hoyle GL, Venn SE, Steadman KJ, Good RB, McAuliffe EJ, Williams ER, Nicotra AB.

Glob Chang Biol. 2013 May;19(5):1549-61. doi: 10.1111/gcb.12135. Epub 2013 Feb 7.


Differential susceptibility of inbred mouse strains to chlorine-induced airway fibrosis.

Mo Y, Chen J, Schlueter CF, Hoyle GW.

Am J Physiol Lung Cell Mol Physiol. 2013 Jan 15;304(2):L92-102. doi: 10.1152/ajplung.00272.2012. Epub 2012 Nov 21.


Repair of tracheal epithelium by basal cells after chlorine-induced injury.

Musah S, Chen J, Hoyle GW.

Respir Res. 2012 Nov 22;13:107. doi: 10.1186/1465-9921-13-107.


Inhibition of chlorine-induced lung injury by the type 4 phosphodiesterase inhibitor rolipram.

Chang W, Chen J, Schlueter CF, Rando RJ, Pathak YV, Hoyle GW.

Toxicol Appl Pharmacol. 2012 Sep 1;263(2):251-8. doi: 10.1016/j.taap.2012.06.017. Epub 2012 Jul 2.


Tumor necrosis factor-α mediates interactions between macrophages and epithelial cells underlying proinflammatory gene expression induced by particulate matter.

Musah S, DeJarnett N, Hoyle GW.

Toxicology. 2012 Sep 28;299(2-3):125-32. doi: 10.1016/j.tox.2012.05.014. Epub 2012 May 23.


Impaired mouse mammary gland growth and development is mediated by melatonin and its MT1G protein-coupled receptor via repression of ERα, Akt1, and Stat5.

Xiang S, Mao L, Yuan L, Duplessis T, Jones F, Hoyle GW, Frasch T, Dauchy R, Blask DE, Chakravarty G, Hill SM.

J Pineal Res. 2012 Oct;53(3):307-18. doi: 10.1111/j.1600-079X.2012.01000.x. Epub 2012 May 14.


Syndrome of appropriate antidiuretic hormone: difficulties with diagnosing syndrome of inappropriate antidiuretic hormone in older people.

Soiza RL, Hoyle GE.

Intern Med J. 2011 Mar;41(3):295; author reply 296. doi: 10.1111/j.1445-5994.2010.02388.x. No abstract available.


Volaemic assessment of the elderly hyponatraemic patient: reliability of clinical assessment and validation of bioelectrical impedance analysis.

Hoyle GE, Chua M, Soiza RL.

QJM. 2011 Jan;104(1):35-9. doi: 10.1093/qjmed/hcq157. Epub 2010 Sep 7.


Deviations from Haber's Law for multiple measures of acute lung injury in chlorine-exposed mice.

Hoyle GW, Chang W, Chen J, Schlueter CF, Rando RJ.

Toxicol Sci. 2010 Dec;118(2):696-703. doi: 10.1093/toxsci/kfq264. Epub 2010 Sep 6.


Mitigation of chlorine lung injury by increasing cyclic AMP levels.

Hoyle GW.

Proc Am Thorac Soc. 2010 Jul;7(4):284-9. doi: 10.1513/pats.201001-002SM. Review.


Identification of triptolide, a natural diterpenoid compound, as an inhibitor of lung inflammation.

Hoyle GW, Hoyle CI, Chen J, Chang W, Williams RW, Rando RJ.

Am J Physiol Lung Cell Mol Physiol. 2010 Jun;298(6):L830-6. doi: 10.1152/ajplung.00014.2010. Epub 2010 Mar 26.


Systemic inhibition of NF-kappaB activation protects from silicosis.

Di Giuseppe M, Gambelli F, Hoyle GW, Lungarella G, Studer SM, Richards T, Yousem S, McCurry K, Dauber J, Kaminski N, Leikauf G, Ortiz LA.

PLoS One. 2009 May 25;4(5):e5689. doi: 10.1371/journal.pone.0005689.


Common pathways for activation of proinflammatory gene expression by G protein-coupled receptors in primary lung epithelial and endothelial cells.

Chang W, Chen J, Schlueter CF, Hoyle GW.

Exp Lung Res. 2009 May;35(4):324-43. doi: 10.1080/01902140802712738.


White matter lesions and endothelial dysfunction measured by pulse wave analysis.

Soiza RL, Hoyle GE, Murray AD, Prasad D, Seymour DG, Williams DJ.

Geriatr Gerontol Int. 2008 Sep;8(3):209-11. doi: 10.1111/j.1447-0594.2008.00472.x. No abstract available.


Acute lung injury induced by chlorine inhalation in C57BL/6 and FVB/N mice.

Tian X, Tao H, Brisolara J, Chen J, Rando RJ, Hoyle GW.

Inhal Toxicol. 2008 Jul;20(9):783-93. doi: 10.1080/08958370802007841 .


Pre- and post-harvest influences on seed dormancy status of an Australian Goodeniaceae species, Goodenia fascicularis.

Hoyle GL, Steadman KJ, Daws MI, Adkins SW.

Ann Bot. 2008 Jul;102(1):93-101. doi: 10.1093/aob/mcn062. Epub 2008 Apr 21.


Mimicking a semi-arid tropical environment achieves dormancy alleviation for seeds of Australian native Goodeniaceae and Asteraceae.

Hoyle GL, Daws MI, Steadman KJ, Adkins SW.

Ann Bot. 2008 Apr;101(5):701-8. doi: 10.1093/aob/mcn009. Epub 2008 Jan 31.


Medical student attitudes toward older people and willingness to consider a career in geriatric medicine.

Hughes NJ, Soiza RL, Chua M, Hoyle GE, MacDonald A, Primrose WR, Seymour DG.

J Am Geriatr Soc. 2008 Feb;56(2):334-8. doi: 10.1111/j.1532-5415.2007.01552.x. Epub 2007 Dec 26.


Epithelial expression of TIMP-1 does not alter sensitivity to bleomycin-induced lung injury in C57BL/6 mice.

Fattman CL, Gambelli F, Hoyle G, Pitt BR, Ortiz LA.

Am J Physiol Lung Cell Mol Physiol. 2008 Mar;294(3):L572-81. doi: 10.1152/ajplung.00291.2007. Epub 2008 Jan 4.


Neuronal modulation of lung injury induced by polymeric hexamethylene diisocyanate in mice.

Lee CT, Poovey HG, Rando RJ, Hoyle GW.

Toxicol Appl Pharmacol. 2007 Oct 1;224(1):19-28. Epub 2007 Jun 27.


Erythropoietin, a hypoxia-regulated factor, elicits a pro-angiogenic program in human mesenchymal stem cells.

Zwezdaryk KJ, Coffelt SB, Figueroa YG, Liu J, Phinney DG, LaMarca HL, Florez L, Morris CB, Hoyle GW, Scandurro AB.

Exp Hematol. 2007 Apr;35(4):640-52. Erratum in: Exp Hematol. 2007 Jul;35(7):1153-61.


Prognostic implications of hyponatremia in elderly hospitalized patients.

Chua M, Hoyle GE, Soiza RL.

Arch Gerontol Geriatr. 2007 Nov-Dec;45(3):253-8. Epub 2007 Jan 22.


Tachykinin-1 receptor stimulates proinflammatory gene expression in lung epithelial cells through activation of NF-kappaB via a G(q)-dependent pathway.

Williams R, Zou X, Hoyle GW.

Am J Physiol Lung Cell Mol Physiol. 2007 Feb;292(2):L430-7. Epub 2006 Oct 13.


Distributed situation awareness in dynamic systems: theoretical development and application of an ergonomics methodology.

Stanton NA, Stewart R, Harris D, Houghton RJ, Baber C, McMaster R, Salmon P, Hoyle G, Walker G, Young MS, Linsell M, Dymott R, Green D.

Ergonomics. 2006 Oct 10-22;49(12-13):1288-311.


The Hsp90 cochaperone p23 is essential for perinatal survival.

Grad I, McKee TA, Ludwig SM, Hoyle GW, Ruiz P, Wurst W, Floss T, Miller CA 3rd, Picard D.

Mol Cell Biol. 2006 Dec;26(23):8976-83. Epub 2006 Sep 25.


Prevalence of hyponatremia in elderly patients.

Hoyle GE, Chua M, Soiza RL.

J Am Geriatr Soc. 2006 Sep;54(9):1473; author reply 1473-4. No abstract available.


Over-expression of PDGF-C using a lung specific promoter results in abnormal lung development.

Zhuo Y, Hoyle GW, Shan B, Levy DR, Lasky JA.

Transgenic Res. 2006 Oct;15(5):543-55. Epub 2006 Jul 9.


A mysterious case of normalising blood sugar: insulinoma in a long-standing diabetic patient.

Hameed MF, Hoyle GE, Muir Z.

Age Ageing. 2006 May;35(3):317-8.


Gene expression profiling in mouse lung following polymeric hexamethylene diisocyanate exposure.

Lee CT, Ylostalo J, Friedman M, Hoyle GW.

Toxicol Appl Pharmacol. 2005 May 15;205(1):53-64. Epub 2004 Nov 18.


Effect of platelet-derived growth factor on the development and persistence of asbestos-induced fibroproliferative lung disease.

Li J, Poovey HG, Rodriguez JF, Brody A, Hoyle GW.

J Environ Pathol Toxicol Oncol. 2004;23(4):253-66.


Dendritic cell subsets differentially regulate angiogenesis in human ovarian cancer.

Curiel TJ, Cheng P, Mottram P, Alvarez X, Moons L, Evdemon-Hogan M, Wei S, Zou L, Kryczek I, Hoyle G, Lackner A, Carmeliet P, Zou W.

Cancer Res. 2004 Aug 15;64(16):5535-8.


Nerve growth factor induces increased airway inflammation via a neuropeptide-dependent mechanism in a transgenic animal model of allergic airway inflammation.

Quarcoo D, Schulte-Herbrüggen O, Lommatzsch M, Schierhorn K, Hoyle GW, Renz H, Braun A.

Clin Exp Allergy. 2004 Jul;34(7):1146-51.


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