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Items: 1 to 50 of 103

1.

A D-enantiomeric peptide interferes with hetero-association of amyloid-β oligomers and prion protein.

Rösener NS, Gremer L, Reinartz E, König A, Brener O, Heise H, Hoyer W, Neudecker P, Willbold D.

J Biol Chem. 2018 Aug 21. pii: jbc.RA118.003116. doi: 10.1074/jbc.RA118.003116. [Epub ahead of print]

2.

Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling.

Duggimpudi S, Kloetgen A, Maney SK, Münch PC, Hezaveh K, Shaykhalishahi H, Hoyer W, McHardy AC, Lang PA, Borkhardt A, Hoell JI.

J Biol Chem. 2018 Aug 20. pii: jbc.RA118.002243. doi: 10.1074/jbc.RA118.002243. [Epub ahead of print]

3.

Origin of metastable oligomers and their effects on amyloid fibril self-assembly.

Hasecke F, Miti T, Perez C, Barton J, Schölzel D, Gremer L, Grüning CSR, Matthews G, Meisl G, Knowles TPJ, Willbold D, Neudecker P, Heise H, Ullah G, Hoyer W, Muschol M.

Chem Sci. 2018 Jun 13;9(27):5937-5948. doi: 10.1039/c8sc01479e. eCollection 2018 Jul 21.

4.

α-Synuclein Aggregation Monitored by Thioflavin T Fluorescence Assay.

Wördehoff MM, Hoyer W.

Bio Protoc. 2018 Jul 20;8(14). pii: e2941. doi: 10.21769/BioProtoc.2941.

5.

DNP-Enhanced MAS NMR: A Tool to Snapshot Conformational Ensembles of α-Synuclein in Different States.

Uluca B, Viennet T, Petrović D, Shaykhalishahi H, Weirich F, Gönülalan A, Strodel B, Etzkorn M, Hoyer W, Heise H.

Biophys J. 2018 Apr 10;114(7):1614-1623. doi: 10.1016/j.bpj.2018.02.011.

6.

Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth.

Wördehoff MM, Shaykhalishahi H, Groß L, Gremer L, Stoldt M, Buell AK, Willbold D, Hoyer W.

J Mol Biol. 2017 Oct 13;429(20):3018-3030. doi: 10.1016/j.jmb.2017.09.005. Epub 2017 Sep 13.

7.

Fibril structure of amyloid-β(1-42) by cryo-electron microscopy.

Gremer L, Schölzel D, Schenk C, Reinartz E, Labahn J, Ravelli RBG, Tusche M, Lopez-Iglesias C, Hoyer W, Heise H, Willbold D, Schröder GF.

Science. 2017 Oct 6;358(6359):116-119. doi: 10.1126/science.aao2825. Epub 2017 Sep 7.

8.

Uncovering the Binding and Specificity of β-Wrapins for Amyloid-β and α-Synuclein.

Orr AA, Wördehoff MM, Hoyer W, Tamamis P.

J Phys Chem B. 2016 Dec 22;120(50):12781-12794. doi: 10.1021/acs.jpcb.6b08485. Epub 2016 Dec 9.

PMID:
27934063
9.

β-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor.

Mirecka EA, Feuerstein S, Gremer L, Schröder GF, Stoldt M, Willbold D, Hoyer W.

Sci Rep. 2016 Sep 19;6:33474. doi: 10.1038/srep33474.

10.

Structural Characterization of Fibrils from Recombinant Human Islet Amyloid Polypeptide by Solid-State NMR: The Central FGAILS Segment Is Part of the β-Sheet Core.

Weirich F, Gremer L, Mirecka EA, Schiefer S, Hoyer W, Heise H.

PLoS One. 2016 Sep 8;11(9):e0161243. doi: 10.1371/journal.pone.0161243. eCollection 2016.

11.

QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers.

Brener O, Dunkelmann T, Gremer L, van Groen T, Mirecka EA, Kadish I, Willuweit A, Kutzsche J, Jürgens D, Rudolph S, Tusche M, Bongen P, Pietruszka J, Oesterhelt F, Langen KJ, Demuth HU, Janssen A, Hoyer W, Funke SA, Nagel-Steger L, Willbold D.

Sci Rep. 2015 Sep 23;5:13222. doi: 10.1038/srep13222.

12.

Contact between the β1 and β2 Segments of α-Synuclein that Inhibits Amyloid Formation.

Shaykhalishahi H, Gauhar A, Wördehoff MM, Grüning CS, Klein AN, Bannach O, Stoldt M, Willbold D, Härd T, Hoyer W.

Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8837-40. doi: 10.1002/anie.201503018. Epub 2015 Jun 26.

PMID:
26119103
13.

Single fibril growth kinetics of α-synuclein.

Wördehoff MM, Bannach O, Shaykhalishahi H, Kulawik A, Schiefer S, Willbold D, Hoyer W, Birkmann E.

J Mol Biol. 2015 Mar 27;427(6 Pt B):1428-1435. doi: 10.1016/j.jmb.2015.01.020. Epub 2015 Feb 4.

PMID:
25659910
14.

A β-hairpin-binding protein for three different disease-related amyloidogenic proteins.

Shaykhalishahi H, Mirecka EA, Gauhar A, Grüning CS, Willbold D, Härd T, Stoldt M, Hoyer W.

Chembiochem. 2015 Feb 9;16(3):411-4. doi: 10.1002/cbic.201402552. Epub 2014 Dec 30.

PMID:
25557164
15.

Impact of subunit linkages in an engineered homodimeric binding protein to α-synuclein.

Gauhar A, Shaykhalishahi H, Gremer L, Mirecka EA, Hoyer W.

Protein Eng Des Sel. 2014 Dec;27(12):473-9. doi: 10.1093/protein/gzu047. Epub 2014 Oct 20.

PMID:
25332193
16.

Alternative conformations of the Tau repeat domain in complex with an engineered binding protein.

Grüning CS, Mirecka EA, Klein AN, Mandelkow E, Willbold D, Marino SF, Stoldt M, Hoyer W.

J Biol Chem. 2014 Aug 15;289(33):23209-18. doi: 10.1074/jbc.M114.560920. Epub 2014 Jun 25.

17.

Engineered aggregation inhibitor fusion for production of highly amyloidogenic human islet amyloid polypeptide.

Mirecka EA, Gremer L, Schiefer S, Oesterhelt F, Stoldt M, Willbold D, Hoyer W.

J Biotechnol. 2014 Dec 10;191:221-7. doi: 10.1016/j.jbiotec.2014.06.006. Epub 2014 Jun 11.

PMID:
24928165
18.

Sequestration of a β-hairpin for control of α-synuclein aggregation.

Mirecka EA, Shaykhalishahi H, Gauhar A, Akgül Ş, Lecher J, Willbold D, Stoldt M, Hoyer W.

Angew Chem Int Ed Engl. 2014 Apr 14;53(16):4227-30. doi: 10.1002/anie.201309001. Epub 2014 Mar 12.

PMID:
24623599
19.

The off-rate of monomers dissociating from amyloid-β protofibrils.

Grüning CS, Klinker S, Wolff M, Schneider M, Toksöz K, Klein AN, Nagel-Steger L, Willbold D, Hoyer W.

J Biol Chem. 2013 Dec 27;288(52):37104-11. doi: 10.1074/jbc.M113.513432. Epub 2013 Nov 18.

20.

Effects of spacing of item repetitions in continuous recognition memory: does item retrieval difficulty promote item retention in older adults?

Kılıç A, Hoyer WJ, Howard MW.

Exp Aging Res. 2013;39(3):322-41. doi: 10.1080/0361073X.2013.779200.

PMID:
23607400
21.

New method for density determination of nanoparticles using a CPS disc centrifuge™.

Neumann A, Hoyer W, Wolff MW, Reichl U, Pfitzner A, Roth B.

Colloids Surf B Biointerfaces. 2013 Apr 1;104:27-31. doi: 10.1016/j.colsurfb.2012.11.014. Epub 2012 Dec 6.

PMID:
23298584
22.

A search-by-clusters model of visual search: fits to data from younger and older adults.

Hoyer WJ, Cerella J, Buchler NG.

J Gerontol B Psychol Sci Soc Sci. 2011 Jul;66(4):402-10. doi: 10.1093/geronb/gbr022. Epub 2011 Mar 31.

23.

On the atomic structure of Zr60Cu20Fe20 metallic glass.

Kaban I, Jóvári P, Stoica M, Mattern N, Eckert J, Hoyer W, Beuneu B.

J Phys Condens Matter. 2010 Oct 13;22(40):404208. doi: 10.1088/0953-8984/22/40/404208. Epub 2010 Sep 22.

PMID:
21386569
24.

Structure of GeSe4-In and GeSe5-In glasses.

Kaban I, Jóvári P, Petkova T, Petkov P, Stoilova A, Hoyer W, Beuneu B.

J Phys Condens Matter. 2010 Oct 13;22(40):404205. doi: 10.1088/0953-8984/22/40/404205. Epub 2010 Sep 22.

PMID:
21386566
25.

Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo.

Luheshi LM, Hoyer W, de Barros TP, van Dijk Härd I, Brorsson AC, Macao B, Persson C, Crowther DC, Lomas DA, Ståhl S, Dobson CM, Härd T.

PLoS Biol. 2010 Mar 16;8(3):e1000334. doi: 10.1371/journal.pbio.1000334.

26.

Transfer of instances in cognitive skill learning: adult age differences.

D'Eredita MA, Hoyer WJ.

Exp Aging Res. 2010 Jan-Mar;36(1):23-39. doi: 10.1080/03610730903418646.

PMID:
20054725
27.

Atomic structure of As(2)S(3)-Ag chalcogenide glasses.

Kaban I, Jóvári P, Wagner T, Frumar M, Stehlik S, Bartos M, Hoyer W, Beuneu B, Webb MA.

J Phys Condens Matter. 2009 Sep 30;21(39):395801. doi: 10.1088/0953-8984/21/39/395801. Epub 2009 Sep 8.

PMID:
21832397
28.

Nanocomposites with structure domains of 0.5 to 3 nm by polymerization of silicon spiro compounds.

Spange S, Kempe P, Seifert A, Auer AA, Ecorchard P, Lang H, Falke M, Hietschold M, Pohlers A, Hoyer W, Cox G, Kockrick E, Kaskel S.

Angew Chem Int Ed Engl. 2009;48(44):8254-8. doi: 10.1002/anie.200901113. No abstract available.

PMID:
19784975
29.

On the atomic structure of liquid Ni-Si alloys: a neutron diffraction study.

Gruner S, Marczinke J, Hennet L, Hoyer W, Cuello GJ.

J Phys Condens Matter. 2009 Sep 23;21(38):385403. doi: 10.1088/0953-8984/21/38/385403. Epub 2009 Aug 24.

PMID:
21832368
30.

Segregation and temperature effect on the atomic structure of Bi(30)Ga(70) liquid alloy.

Sbihi DE, Grosdidier B, Kaban I, Gruner S, Hoyer W, Gasser JG.

J Phys Condens Matter. 2009 Jun 17;21(24):245107. doi: 10.1088/0953-8984/21/24/245107. Epub 2009 May 21.

PMID:
21693940
31.

Recombinant amyloid beta-peptide production by coexpression with an affibody ligand.

Macao B, Hoyer W, Sandberg A, Brorsson AC, Dobson CM, Härd T.

BMC Biotechnol. 2008 Oct 30;8:82. doi: 10.1186/1472-6750-8-82.

32.

Second-harmonic generation from complementary split-ring resonators.

Feth N, Linden S, Klein MW, Decker M, Niesler FB, Zeng Y, Hoyer W, Liu J, Koch SW, Moloney JV, Wegener M.

Opt Lett. 2008 Sep 1;33(17):1975-7.

PMID:
18758583
33.
34.

Radiation-modified structure of Ge25Sb15S60 and Ge35Sb5S60 glasses.

Kavetskyy T, Shpotyuk O, Kaban I, Hoyer W.

J Chem Phys. 2008 Jun 28;128(24):244514. doi: 10.1063/1.2945300.

PMID:
18601355
35.

Effects of item difficulty on the retrieval of solutions during cognitive skill acquisition: age differences.

Onyper SV, Hoyer WJ, Cerella J.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2008 May;15(3):358-83. doi: 10.1080/13825580701879907.

PMID:
18421628
36.

Stabilization of a beta-hairpin in monomeric Alzheimer's amyloid-beta peptide inhibits amyloid formation.

Hoyer W, Grönwall C, Jonsson A, Ståhl S, Härd T.

Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5099-104. doi: 10.1073/pnas.0711731105. Epub 2008 Mar 28.

37.

Interaction of Alzheimer's A beta peptide with an engineered binding protein--thermodynamics and kinetics of coupled folding-binding.

Hoyer W, Härd T.

J Mol Biol. 2008 Apr 25;378(2):398-411. doi: 10.1016/j.jmb.2008.02.040. Epub 2008 Mar 4.

PMID:
18358490
38.
39.

Atomic structure of As(25)Si(40)Te(35) glass.

Kaban I, Gruner S, Jóvári P, Kehr M, Hoyer W, Delaplane RG, Popescu M.

J Phys Condens Matter. 2007 Aug 22;19(33):335210. doi: 10.1088/0953-8984/19/33/335210. Epub 2007 Jul 4.

PMID:
21694133
40.

Acute alcohol intoxication impairs controlled search across the visual field.

Hoyer WJ, Semenec SC, Buchler NE.

J Stud Alcohol Drugs. 2007 Sep;68(5):748-58.

PMID:
17690809
41.

Aging, focus switching, and task switching in a continuous calculation task: evidence toward a new working memory control process.

Verhaeghen P, Hoyer WJ.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2007 Jan;14(1):22-39.

PMID:
17164188
42.

Characterization of disorder in semiconductors via single-photon interferometry.

Bozsoki P, Thomas P, Kira M, Hoyer W, Meier T, Koch SW, Maschke K, Varga I, Stolz H.

Phys Rev Lett. 2006 Dec 1;97(22):227402. Epub 2006 Nov 30.

PMID:
17155841
43.

The associative-memory basis of cognitive skill learning: adult age differences.

Cerella J, Onyper SV, Hoyer WJ.

Psychol Aging. 2006 Sep;21(3):483-98.

PMID:
16953711
44.

Determinants of retrieval solutions during cognitive skill training: source confusions.

Onyper SV, Hoyer WJ, Cerella J.

Mem Cognit. 2006 Apr;34(3):538-49.

PMID:
16933763
45.
46.

Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR.

Heise H, Hoyer W, Becker S, Andronesi OC, Riedel D, Baldus M.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15871-6. Epub 2005 Oct 24.

47.

Photoluminescence and terahertz emission from femtosecond laser-induced plasma channels.

Hoyer W, Knorr A, Moloney JV, Wright EM, Kira M, Koch SW.

Phys Rev Lett. 2005 Mar 25;94(11):115004. Epub 2005 Mar 24.

PMID:
15903868
48.

Structural characterization of copper(II) binding to alpha-synuclein: Insights into the bioinorganic chemistry of Parkinson's disease.

Rasia RM, Bertoncini CW, Marsh D, Hoyer W, Cherny D, Zweckstetter M, Griesinger C, Jovin TM, Fernández CO.

Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4294-9. Epub 2005 Mar 14.

49.

Marketing mental health to men: theoretical and practical considerations.

Rochlen AB, Hoyer WD.

J Clin Psychol. 2005 Jun;61(6):675-84.

PMID:
15732086
50.

Release of long-range tertiary interactions potentiates aggregation of natively unstructured alpha-synuclein.

Bertoncini CW, Jung YS, Fernandez CO, Hoyer W, Griesinger C, Jovin TM, Zweckstetter M.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1430-5. Epub 2005 Jan 25.

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