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Elevated miR-615-3p Expression Predicts Adverse Clinical Outcome and Promotes Proliferation and Migration of Prostate Cancer Cells.

Laursen EB, Fredsøe J, Schmidt L, Strand S, Kristensen H, Ildor Rasmussen AK, Daugaard TF, Mouritzen P, Høyer S, Kristensen G, Stroomberg HV, Brasso K, Røder MA, Borre M, Sørensen KD.

Am J Pathol. 2019 Sep 17. pii: S0002-9440(19)30711-4. doi: 10.1016/j.ajpath.2019.08.007. [Epub ahead of print]


The relationship between tumor aggressiveness and cholinergic PET imaging in prostate cancer tissue. A proof-of-concept study.

Nielsen MM, Tolbod LP, Borre M, Høyer S, Harms HJ, Sørensen J, Frøkiær J, Borghammer P.

Am J Nucl Med Mol Imaging. 2019 Jun 15;9(3):185-192. eCollection 2019.


Free-Form Diffractive Metagrating Design Based on Generative Adversarial Networks.

Jiang J, Sell D, Hoyer S, Hickey J, Yang J, Fan JA.

ACS Nano. 2019 Aug 27;13(8):8872-8878. doi: 10.1021/acsnano.9b02371. Epub 2019 Jul 22.


Learning data-driven discretizations for partial differential equations.

Bar-Sinai Y, Hoyer S, Hickey J, Brenner MP.

Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15344-15349. doi: 10.1073/pnas.1814058116. Epub 2019 Jul 16.


A novel combined miRNA and methylation marker panel (miMe) for prediction of prostate cancer outcome after radical prostatectomy.

Strand SH, Bavafaye-Haghighi E, Kristensen H, Rasmussen AK, Hoyer S, Borre M, Mouritzen P, Besenbacher S, Orntoft TF, Sorensen KD.

Int J Cancer. 2019 May 24. doi: 10.1002/ijc.32427. [Epub ahead of print]


5hmC Level Predicts Biochemical Failure Following Radical Prostatectomy in Prostate Cancer Patients with ERG Negative Tumors.

Kristensen G, Strand SH, Røder MA, Berg KD, Toft BG, Høyer S, Borre M, Sørensen KD, Brasso K.

Int J Mol Sci. 2019 Feb 27;20(5). pii: E1025. doi: 10.3390/ijms20051025.


Quantitative Tumor Perfusion Imaging with 82Rb PET/CT in Prostate Cancer: Analytic and Clinical Validation.

Jochumsen MR, Tolbod LP, Pedersen BG, Nielsen MM, Høyer S, Frøkiær J, Borre M, Bouchelouche K, Sörensen J.

J Nucl Med. 2019 Aug;60(8):1059-1065. doi: 10.2967/jnumed.118.219188. Epub 2019 Jan 25.


Human papillomavirus and squamous cell carcinoma of the urinary bladder: DaBlaCa-10 study.

Jørgensen KR, Høyer S, Jakobsen JK, Jensen TK, Marcussen N, Wrist Lam G, Hasselager T, Thind PO, Toft BG, Steiniche T, Jensen JB.

Scand J Urol. 2018 Oct - Dec;52(5-6):371-376. doi: 10.1080/21681805.2018.1531920. Epub 2018 Dec 11.


Non-invasive quantification of tumor blood flow in prostate cancer using 15O-H2O PET/CT.

Tolbod LP, Nielsen MM, Pedersen BG, Høyer S, Harms HJ, Borre M, Borghammer P, Bouchelouche K, Frøkiær J, Sørensen J.

Am J Nucl Med Mol Imaging. 2018 Oct 20;8(5):292-302. eCollection 2018.


Exploring the transcriptome of hormone-naive multifocal prostate cancer and matched lymph node metastases.

Schmidt L, Møller M, Haldrup C, Strand SH, Vang S, Hedegaard J, Høyer S, Borre M, Ørntoft T, Sørensen KD.

Br J Cancer. 2018 Dec;119(12):1527-1537. doi: 10.1038/s41416-018-0321-5. Epub 2018 Nov 19.


Dysregulation and prognostic potential of 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) levels in prostate cancer.

Storebjerg TM, Strand SH, Høyer S, Lynnerup AS, Borre M, Ørntoft TF, Sørensen KD.

Clin Epigenetics. 2018 Aug 7;10(1):105. doi: 10.1186/s13148-018-0540-x.


Laying the foundation for a core set of the International Classification of Functioning, Disability and Health for community-dwelling adults aged 75 years and above in general practice: a study protocol.

Tomandl J, Book S, Gotthardt S, Heinmueller S, Graessel E, Freiberger E, Kuehlein T, Hueber S, Hoyer S.

BMJ Open. 2018 Aug 5;8(8):e024274. doi: 10.1136/bmjopen-2018-024274.


Training and validation of a novel 4-miRNA ratio model (MiCaP) for prediction of postoperative outcome in prostate cancer patients.

Schmidt L, Fredsøe J, Kristensen H, Strand SH, Rasmussen A, Høyer S, Borre M, Mouritzen P, Ørntoft T, Sørensen KD.

Ann Oncol. 2018 Sep 1;29(9):2003-2009. doi: 10.1093/annonc/mdy243.


Glutamate metabolism in cerebral mitochondria after ischemia and post-ischemic recovery during aging: relationships with brain energy metabolism.

Ferrari F, Gorini A, Hoyer S, Villa RF.

J Neurochem. 2018 Aug;146(4):416-428. doi: 10.1111/jnc.14464. Epub 2018 Aug 1.


Assessing microscope image focus quality with deep learning.

Yang SJ, Berndl M, Michael Ando D, Barch M, Narayanaswamy A, Christiansen E, Hoyer S, Roat C, Hung J, Rueden CT, Shankar A, Finkbeiner S, Nelson P.

BMC Bioinformatics. 2018 Mar 15;19(1):77. doi: 10.1186/s12859-018-2087-4.


Biomarker potential of ST6GALNAC3 and ZNF660 promoter hypermethylation in prostate cancer tissue and liquid biopsies.

Haldrup C, Pedersen AL, Øgaard N, Strand SH, Høyer S, Borre M, Ørntoft TF, Sørensen KD.

Mol Oncol. 2018 Apr;12(4):545-560. doi: 10.1002/1878-0261.12183. Epub 2018 Mar 13.


BRAF and MEK Inhibitors Influence the Function of Reprogrammed T Cells: Consequences for Adoptive T-Cell Therapy.

Dörrie J, Babalija L, Hoyer S, Gerer KF, Schuler G, Heinzerling L, Schaft N.

Int J Mol Sci. 2018 Jan 18;19(1). pii: E289. doi: 10.3390/ijms19010289.


Aquaporin expression in the fetal porcine urinary tract changes during gestation.

Jakobsen LK, Trelborg KF, Kingo PS, Hoyer S, Andersson KE, Djurhuus JC, Norregaard R, Olsen LH.

Physiol Res. 2018 May 4;67(2):283-292. Epub 2018 Jan 5.


Multi-parametric magnetic resonance imaging monitoring patients in active surveillance for prostate cancer: a prospective cohort study.

Elkjær MC, Andersen MH, Høyer S, Pedersen BG, Borre M.

Scand J Urol. 2018 Feb;52(1):8-13. doi: 10.1080/21681805.2017.1409265. Epub 2017 Dec 7.


Frequency and Markers of Precursor Lesions and Implications for the Pathogenesis of Testicular Germ Cell Tumors.

von Eyben FE, Jensen MB, Høyer S.

Clin Genitourin Cancer. 2017 Sep 5. pii: S1558-7673(17)30265-3. doi: 10.1016/j.clgc.2017.08.010. [Epub ahead of print]


Monitoring Treatment Response and Metastatic Relapse in Advanced Bladder Cancer by Liquid Biopsy Analysis.

Birkenkamp-Demtröder K, Christensen E, Nordentoft I, Knudsen M, Taber A, Høyer S, Lamy P, Agerbæk M, Jensen JB, Dyrskjøt L.

Eur Urol. 2018 Apr;73(4):535-540. doi: 10.1016/j.eururo.2017.09.011. Epub 2017 Sep 27.


Comprehensive Evaluation of TFF3 Promoter Hypomethylation and Molecular Biomarker Potential for Prostate Cancer Diagnosis and Prognosis.

Nørgaard M, Haldrup C, Storebjerg TM, Vestergaard EM, Wild PJ, Høyer S, Borre M, Ørntoft TF, Sørensen KD.

Int J Mol Sci. 2017 Sep 20;18(9). pii: E2017. doi: 10.3390/ijms18092017.


Proteomic Response of Human Umbilical Vein Endothelial Cells to Histamine Stimulation.

Emirbayer PE, Sinha A, Ignatchenko V, Hoyer S, Dörrie J, Schaft N, Pischetsrieder M, Kislinger T.

Proteomics. 2017 Nov;17(21). doi: 10.1002/pmic.201700116. Epub 2017 Oct 12.


Comprehensive multiregional analysis of molecular heterogeneity in bladder cancer.

Thomsen MBH, Nordentoft I, Lamy P, Vang S, Reinert L, Mapendano CK, Høyer S, Ørntoft TF, Jensen JB, Dyrskjøt L.

Sci Rep. 2017 Sep 15;7(1):11702. doi: 10.1038/s41598-017-11291-0.


A genetically inducible porcine model of intestinal cancer.

Callesen MM, Árnadóttir SS, Lyskjaer I, Ørntoft MW, Høyer S, Dagnaes-Hansen F, Liu Y, Li R, Callesen H, Rasmussen MH, Berthelsen MF, Thomsen MK, Schweiger PJ, Jensen KB, Laurberg S, Ørntoft TF, Elverløv-Jakobsen JE, Andersen CL.

Mol Oncol. 2017 Nov;11(11):1616-1629. doi: 10.1002/1878-0261.12136. Epub 2017 Oct 10.


Cryoablation of Renal Angiomyolipoma: An Evaluation of Safety and Efficacy.

Makki A, Graumann O, Høyer S, Solvig J, Østraat Ø, Madsen MG, Nielsen TK.

J Endourol. 2017 Nov;31(11):1117-1122. doi: 10.1089/end.2017.0376. Epub 2017 Sep 28.


RNA-transfection of γ/δ T cells with a chimeric antigen receptor or an α/β T-cell receptor: a safer alternative to genetically engineered α/β T cells for the immunotherapy of melanoma.

Harrer DC, Simon B, Fujii SI, Shimizu K, Uslu U, Schuler G, Gerer KF, Hoyer S, Dörrie J, Schaft N.

BMC Cancer. 2017 Aug 17;17(1):551. doi: 10.1186/s12885-017-3539-3.


Diagnostic and Prognostic MicroRNA Biomarkers for Prostate Cancer in Cell-free Urine.

Fredsøe J, Rasmussen AKI, Thomsen AR, Mouritzen P, Høyer S, Borre M, Ørntoft TF, Sørensen KD.

Eur Urol Focus. 2018 Dec;4(6):825-833. doi: 10.1016/j.euf.2017.02.018. Epub 2017 Mar 9.


Detection of Lymph Node Metastasis in Patients with Bladder Cancer using Maximum Standardised Uptake Value and 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography: Results from a High-volume Centre Including Long-term Follow-up.

Vind-Kezunovic S, Bouchelouche K, Ipsen P, Høyer S, Bell C, Bjerggaard Jensen J.

Eur Urol Focus. 2019 Jan;5(1):90-96. doi: 10.1016/j.euf.2017.06.005. Epub 2017 Jun 23.


Prostate cancer: in-bore magnetic resonance guided biopsies at active surveillance inclusion improve selection of patients for active treatment.

Elkjær MC, Andersen MH, Høyer S, Pedersen BG, Borre M.

Acta Radiol. 2018 May;59(5):619-626. doi: 10.1177/0284185117723372. Epub 2017 Jul 26.


Short-term complications for percutaneous ultrasound-guided biopsy of renal masses in adult outpatients.

Rasmussen LR, Loft M, Nielsen TK, Bjødstrup Jensen M, Høyer S, Hørlyck A, Graumann O.

Acta Radiol. 2018 Apr;59(4):491-496. doi: 10.1177/0284185117720855. Epub 2017 Jul 18.


Preclinical evaluation of NF-κB-triggered dendritic cells expressing the viral oncogenic driver of Merkel cell carcinoma for therapeutic vaccination.

Gerer KF, Erdmann M, Hadrup SR, Lyngaa R, Martin LM, Voll RE, Schuler-Thurner B, Schuler G, Schaft N, Hoyer S, Dörrie J.

Ther Adv Med Oncol. 2017 Jul;9(7):451-464. doi: 10.1177/1758834017712630. Epub 2017 Jun 13.


An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes.

Bekker-Jensen DB, Kelstrup CD, Batth TS, Larsen SC, Haldrup C, Bramsen JB, Sørensen KD, Høyer S, Ørntoft TF, Andersen CL, Nielsen ML, Olsen JV.

Cell Syst. 2017 Jun 28;4(6):587-599.e4. doi: 10.1016/j.cels.2017.05.009. Epub 2017 Jun 7.


Prognostic Impact of a 12-gene Progression Score in Non-muscle-invasive Bladder Cancer: A Prospective Multicentre Validation Study.

Dyrskjøt L, Reinert T, Algaba F, Christensen E, Nieboer D, Hermann GG, Mogensen K, Beukers W, Marquez M, Segersten U, Høyer S, Ulhøi BP, Hartmann A, Stöhr R, Wach S, Nawroth R, Schwamborn K, Tulic C, Simic T, Junker K, Harving N, Petersen AC, Jensen JB, Keck B, Grimm MO, Horstmann M, Maurer T, Steyerberg EW, Zwarthoff EC, Real FX, Malats N, Malmström PU, Ørntoft TF.

Eur Urol. 2017 Sep;72(3):461-469. doi: 10.1016/j.eururo.2017.05.040. Epub 2017 Jun 2.


Clinical relevance of narrow-band imaging in flexible cystoscopy: the DaBlaCa-7 study.

Drejer D, Béji S, Munk Nielsen A, Høyer S, Wrist Lam G, Jensen JB.

Scand J Urol. 2017 Apr;51(2):120-123. doi: 10.1080/21681805.2017.1295101. Epub 2017 Mar 7.


Targeted label-free quantification of interleukin-8 in PMA-activated U937 cell secretome by nanoLC-ESI-MS/MS-sSRM.

Emirbayer PE, Gerer KF, Hoyer S, Pischetsrieder M.

Proteomics. 2017 May;17(9). doi: 10.1002/pmic.201600455.


Subcutaneous Lobular Capillary Hemangioma on 68Ga-PSMA PET/CT.

Jochumsen MR, Vendelbo MH, Høyer S, Bouchelouche K.

Clin Nucl Med. 2017 Apr;42(4):e214-e215. doi: 10.1097/RLU.0000000000001542.


Electrocardiographic assessments and cardiac events after fingolimod first dose - a comprehensive monitoring study.

Limmroth V, Ziemssen T, Lang M, Richter S, Wagner B, Haas J, Schmidt S, Gerbershagen K, Lassek C, Klotz L, Hoffmann O, Albert C, Schuh K, Baier-Ebert M, Wendt G, Schieb H, Hoyer S, Dechend R, Haverkamp W.

BMC Neurol. 2017 Jan 18;17(1):11. doi: 10.1186/s12883-016-0789-7.


Human papillomavirus types 44, 52, 66 and 67 detected in a woman with squamous cell carcinoma of the urinary bladder.

Jørgensen KR, Høyer S, Sørensen MM, Jensen JB.

Scand J Urol. 2017 Feb;51(1):85-86. doi: 10.1080/21681805.2016.1271826. Epub 2017 Jan 13.


Heterogeneous patterns of DNA methylation-based field effects in histologically normal prostate tissue from cancer patients.

Møller M, Strand SH, Mundbjerg K, Liang G, Gill I, Haldrup C, Borre M, Høyer S, Ørntoft TF, Sørensen KD.

Sci Rep. 2017 Jan 13;7:40636. doi: 10.1038/srep40636.


Liquid Biopsy Analysis of FGFR3 and PIK3CA Hotspot Mutations for Disease Surveillance in Bladder Cancer.

Christensen E, Birkenkamp-Demtröder K, Nordentoft I, Høyer S, van der Keur K, van Kessel K, Zwarthoff E, Agerbæk M, Ørntoft TF, Jensen JB, Dyrskjøt L.

Eur Urol. 2017 Jun;71(6):961-969. doi: 10.1016/j.eururo.2016.12.016. Epub 2017 Jan 6.


The Missing Link in the Diagnostic Pathway of Prostate Cancer.

Wøyen AV, Laczkó G, Høyer S, Hegyi L.

Pathol Oncol Res. 2017 Apr;23(2):447-450. doi: 10.1007/s12253-016-0183-1. Epub 2017 Jan 4.


RHCG and TCAF1 promoter hypermethylation predicts biochemical recurrence in prostate cancer patients treated by radical prostatectomy.

Strand SH, Switnicki M, Moller M, Haldrup C, Storebjerg TM, Hedegaard J, Nordentoft I, Hoyer S, Borre M, Pedersen JS, Wild PJ, Park JY, Orntoft TF, Sorensen KD.

Oncotarget. 2017 Jan 24;8(4):5774-5788. doi: 10.18632/oncotarget.14391.


Successful treatment of a 67-year-old woman with urethral adenocarcinoma with the use of external beam radiotherapy and image guided adaptive interstitial brachytherapy.

Mujkanovic J, Tanderup K, Agerbæk M, Bisgaard U, Høyer S, Lindegaard JC, Fokdal L.

J Contemp Brachytherapy. 2016 Oct;8(5):434-437. Epub 2016 Nov 7.


Comparison of White Light, Photodynamic Diagnosis, and Narrow-band Imaging in Detection of Carcinoma In Situ or Flat Dysplasia at Transurethral Resection of the Bladder: the DaBlaCa-8 Study.

Drejer D, Béji S, Oezeke R, Nielsen AM, Høyer S, Bjerklund Johansen TE, Lam GW, Jensen JB.

Urology. 2017 Apr;102:138-142. doi: 10.1016/j.urology.2016.11.032. Epub 2016 Nov 25.


The Danish Prostate Cancer Database.

Nguyen-Nielsen M, Høyer S, Friis S, Hansen S, Brasso K, Jakobsen EB, Moe M, Larsson H, Søgaard M, Nakano A, Borre M.

Clin Epidemiol. 2016 Oct 25;8:649-653. eCollection 2016. Review.


Evaluation of robot-assisted laparoscopic versus open cystectomy and effect of carbon dioxide-pneumoperitoneum on histopathological findings in ureteroenteric anastomoses: results from an experimental randomized porcine study.

Kingo PS, Rasmussen TM, Nørregaard R, Borre M, Høyer S, Jensen JB.

Scand J Urol. 2017 Feb;51(1):50-56. doi: 10.1080/21681805.2016.1247294. Epub 2016 Nov 4.


Benzoxazinoids in Prostate Cancer Patients after a Rye-Intensive Diet: Methods and Initial Results.

Steffensen SK, Pedersen HA, Adhikari KB, Laursen BB, Jensen C, Høyer S, Borre M, Pedersen HH, Borre M, Edwards D, Fomsgaard IS.

J Agric Food Chem. 2016 Nov 2;64(43):8235-8245. Epub 2016 Oct 20.


[The development of a generic guideline for multidisciplinary team conferences in Denmark].

Lajer H, Hillingsø J, Høyer S, Rasmussen TR, Hagemann-Madsen RH, Petersen LN, Dehn P, Borre M, Lundvall L.

Ugeskr Laeger. 2016 Sep 26;178(39). pii: V06160408. Danish.


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