Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 45

1.

Lipid and glucose metabolism in hepatocyte cell lines and primary mouse hepatocytes: a comprehensive resource for in vitro studies of hepatic metabolism.

Nagarajan SR, Paul-Heng M, Krycer JR, Fazakerley DJ, Sharland AF, Hoy AJ.

Am J Physiol Endocrinol Metab. 2019 Apr 1;316(4):E578-E589. doi: 10.1152/ajpendo.00365.2018. Epub 2019 Jan 29.

PMID:
30694691
2.

Extracellular Fatty Acids Are the Major Contributor to Lipid Synthesis in Prostate Cancer.

Balaban S, Nassar ZD, Zhang AY, Hosseini-Beheshti E, Centenera MM, Schreuder M, Lin HM, Aishah A, Varney B, Liu-Fu F, Lee LS, Nagarajan SR, Shearer RF, Hardie RA, Raftopulos NL, Kakani MS, Saunders DN, Holst J, Horvath LG, Butler LM, Hoy AJ.

Mol Cancer Res. 2019 Apr;17(4):949-962. doi: 10.1158/1541-7786.MCR-18-0347. Epub 2019 Jan 15.

PMID:
30647103
3.

Altered hepatic glucose homeostasis in AnxA6-KO mice fed a high-fat diet.

Cairns R, Fischer AW, Blanco-Munoz P, Alvarez-Guaita A, Meneses-Salas E, Egert A, Buechler C, Hoy AJ, Heeren J, Enrich C, Rentero C, Grewal T.

PLoS One. 2018 Aug 15;13(8):e0201310. doi: 10.1371/journal.pone.0201310. eCollection 2018.

4.

Heterogeneity of fatty acid metabolism in breast cancer cells underlies differential sensitivity to palmitate-induced apoptosis.

Balaban S, Lee LS, Varney B, Aishah A, Gao Q, Shearer RF, Saunders DN, Grewal T, Hoy AJ.

Mol Oncol. 2018 Sep;12(9):1623-1638. doi: 10.1002/1878-0261.12368. Epub 2018 Aug 29.

5.

The inverse relationship between prostate specific antigen (PSA) and obesity.

Aref AT, Vincent AD, O'Callaghan ME, Martin SA, Sutherland PD, Hoy AJ, Butler LM, Wittert GA.

Endocr Relat Cancer. 2018 Nov;25(11):933-941. doi: 10.1530/ERC-17-0438. Epub 2018 Jun 25.

6.

Metabolic remodeling induced by adipocytes: a new Achilles' heel in invasive breast cancer?

Attane C, Milhas D, Hoy AJ, Muller C.

Curr Med Chem. 2018 Apr 26. doi: 10.2174/0929867325666180426165001. [Epub ahead of print]

PMID:
29708068
7.

Peri-prostatic adipose tissue: the metabolic microenvironment of prostate cancer.

Nassar ZD, Aref AT, Miladinovic D, Mah CY, Raj GV, Hoy AJ, Butler LM.

BJU Int. 2018 May;121 Suppl 3:9-21. doi: 10.1111/bju.14173. Epub 2018 Mar 26. Review.

8.

Correction: Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver.

Nagarajan SR, Brandon AE, McKenna JA, Shtein HC, Nguyen TQ, Suryana E, Poronnik P, Cooney GJ, Saunders DN, Hoy AJ.

PLoS One. 2017 Sep 8;12(9):e0184610. doi: 10.1371/journal.pone.0184610. eCollection 2017.

9.

A distinct plasma lipid signature associated with poor prognosis in castration-resistant prostate cancer.

Lin HM, Mahon KL, Weir JM, Mundra PA, Spielman C, Briscoe K, Gurney H, Mallesara G, Marx G, Stockler MR, PRIMe Consortium, Parton RG, Hoy AJ, Daly RJ, Meikle PJ, Horvath LG.

Int J Cancer. 2017 Nov 15;141(10):2112-2120. doi: 10.1002/ijc.30903. Epub 2017 Aug 8.

10.

Role of hepatic Annexin A6 in fatty acid-induced lipid droplet formation.

Cairns R, Alvarez-Guaita A, Martínez-Saludes I, Wason SJ, Hanh J, Nagarajan SR, Hosseini-Beheshti E, Monastyrskaya K, Hoy AJ, Buechler C, Enrich C, Rentero C, Grewal T.

Exp Cell Res. 2017 Sep 15;358(2):397-410. doi: 10.1016/j.yexcr.2017.07.015. Epub 2017 Jul 14.

PMID:
28712927
11.

Adipocyte-Tumor Cell Metabolic Crosstalk in Breast Cancer.

Hoy AJ, Balaban S, Saunders DN.

Trends Mol Med. 2017 May;23(5):381-392. doi: 10.1016/j.molmed.2017.02.009. Epub 2017 Mar 19. Review.

PMID:
28330687
12.

Insulin and diet-induced changes in the ubiquitin-modified proteome of rat liver.

Nagarajan SR, Brandon AE, McKenna JA, Shtein HC, Nguyen TQ, Suryana E, Poronnik P, Cooney GJ, Saunders DN, Hoy AJ.

PLoS One. 2017 Mar 22;12(3):e0174431. doi: 10.1371/journal.pone.0174431. eCollection 2017. Erratum in: PLoS One. 2017 Sep 8;12 (9):e0184610.

13.

Mitochondrial mutations and metabolic adaptation in pancreatic cancer.

Hardie RA, van Dam E, Cowley M, Han TL, Balaban S, Pajic M, Pinese M, Iconomou M, Shearer RF, McKenna J, Miller D, Waddell N, Pearson JV, Grimmond SM; Australian Pancreatic Cancer Genome Initiative, Sazanov L, Biankin AV, Villas-Boas S, Hoy AJ, Turner N, Saunders DN.

Cancer Metab. 2017 Jan 30;5:2. doi: 10.1186/s40170-017-0164-1. eCollection 2017.

14.

Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration.

Balaban S, Shearer RF, Lee LS, van Geldermalsen M, Schreuder M, Shtein HC, Cairns R, Thomas KC, Fazakerley DJ, Grewal T, Holst J, Saunders DN, Hoy AJ.

Cancer Metab. 2017 Jan 13;5:1. doi: 10.1186/s40170-016-0163-7. eCollection 2017.

15.

Annexin A6 protein is downregulated in human hepatocellular carcinoma.

Meier EM, Rein-Fischboeck L, Pohl R, Wanninger J, Hoy AJ, Grewal T, Eisinger K, Krautbauer S, Liebisch G, Weiss TS, Buechler C.

Mol Cell Biochem. 2016 Jul;418(1-2):81-90. doi: 10.1007/s11010-016-2735-9. Epub 2016 Jun 23.

PMID:
27334756
16.

Identification of dual PPARα/γ agonists and their effects on lipid metabolism.

Gao Q, Hanh J, Váradi L, Cairns R, Sjöström H, Liao VW, Wood P, Balaban S, Ong JA, Lin HY, Lai F, Hoy AJ, Grewal T, Groundwater PW, Hibbs DE.

Bioorg Med Chem. 2015 Dec 15;23(24):7676-84. doi: 10.1016/j.bmc.2015.11.013. Epub 2015 Nov 14.

PMID:
26616289
17.

Fetuin B Is a Secreted Hepatocyte Factor Linking Steatosis to Impaired Glucose Metabolism.

Meex RC, Hoy AJ, Morris A, Brown RD, Lo JC, Burke M, Goode RJ, Kingwell BA, Kraakman MJ, Febbraio MA, Greve JW, Rensen SS, Molloy MP, Lancaster GI, Bruce CR, Watt MJ.

Cell Metab. 2015 Dec 1;22(6):1078-89. doi: 10.1016/j.cmet.2015.09.023. Epub 2015 Oct 22.

18.

TPD52 expression increases neutral lipid storage within cultured cells.

Kamili A, Roslan N, Frost S, Cantrill LC, Wang D, Della-Franca A, Bright RK, Groblewski GE, Straub BK, Hoy AJ, Chen Y, Byrne JA.

J Cell Sci. 2015 Sep 1;128(17):3223-38. doi: 10.1242/jcs.167692. Epub 2015 Jul 16.

19.

Obesity and cancer progression: is there a role of fatty acid metabolism?

Balaban S, Lee LS, Schreuder M, Hoy AJ.

Biomed Res Int. 2015;2015:274585. doi: 10.1155/2015/274585. Epub 2015 Mar 19. Review.

20.

ATGL-mediated triglyceride turnover and the regulation of mitochondrial capacity in skeletal muscle.

Meex RC, Hoy AJ, Mason RM, Martin SD, McGee SL, Bruce CR, Watt MJ.

Am J Physiol Endocrinol Metab. 2015 Jun 1;308(11):E960-70. doi: 10.1152/ajpendo.00598.2014. Epub 2015 Apr 7.

21.

Targeting ASCT2-mediated glutamine uptake blocks prostate cancer growth and tumour development.

Wang Q, Hardie RA, Hoy AJ, van Geldermalsen M, Gao D, Fazli L, Sadowski MC, Balaban S, Schreuder M, Nagarajah R, Wong JJ, Metierre C, Pinello N, Otte NJ, Lehman ML, Gleave M, Nelson CC, Bailey CG, Ritchie W, Rasko JE, Holst J.

J Pathol. 2015 Jul;236(3):278-89. doi: 10.1002/path.4518. Epub 2015 Apr 7.

22.

Evidence that diet-induced hyperleptinemia, but not hypothalamic gliosis, causes ghrelin resistance in NPY/AgRP neurons of male mice.

Briggs DI, Lockie SH, Benzler J, Wu Q, Stark R, Reichenbach A, Hoy AJ, Lemus MB, Coleman HA, Parkington HC, Tups A, Andrews ZB.

Endocrinology. 2014 Jul;155(7):2411-22. doi: 10.1210/en.2013-1861. Epub 2014 Apr 17.

PMID:
24742194
23.

Uptake of 25-hydroxyvitamin D by muscle and fat cells.

Abboud M, Gordon-Thomson C, Hoy AJ, Balaban S, Rybchyn MS, Cole L, Su Y, Brennan-Speranza TC, Fraser DR, Mason RS.

J Steroid Biochem Mol Biol. 2014 Oct;144 Pt A:232-6. doi: 10.1016/j.jsbmb.2013.10.020. Epub 2013 Nov 1. Review.

PMID:
24189546
24.

Compound K modulates fatty acid-induced lipid droplet formation and expression of proteins involved in lipid metabolism in hepatocytes.

Kim MS, Lee KT, Iseli TJ, Hoy AJ, George J, Grewal T, Roufogalis BD.

Liver Int. 2013 Nov;33(10):1583-93. doi: 10.1111/liv.12287. Epub 2013 Sep 2.

PMID:
23998390
25.

Loss of Krüppel-like factor 3 (KLF3/BKLF) leads to upregulation of the insulin-sensitizing factor adipolin (FAM132A/CTRP12/C1qdc2).

Bell-Anderson KS, Funnell AP, Williams H, Mat Jusoh H, Scully T, Lim WF, Burdach JG, Mak KS, Knights AJ, Hoy AJ, Nicholas HR, Sainsbury A, Turner N, Pearson RC, Crossley M.

Diabetes. 2013 Aug;62(8):2728-37. doi: 10.2337/db12-1745. Epub 2013 Apr 30.

26.

Autologous pump-perfused rat hind limb preparation for investigating muscle function and metabolism in vivo.

Peoples GE, Hoy AJ, Henry R, McLennan PL.

Microcirculation. 2013 Aug;20(6):511-23. doi: 10.1111/micc.12048.

PMID:
23413809
27.

Ceramides contained in LDL are elevated in type 2 diabetes and promote inflammation and skeletal muscle insulin resistance.

Boon J, Hoy AJ, Stark R, Brown RD, Meex RC, Henstridge DC, Schenk S, Meikle PJ, Horowitz JF, Kingwell BA, Bruce CR, Watt MJ.

Diabetes. 2013 Feb;62(2):401-10. doi: 10.2337/db12-0686. Epub 2012 Nov 8.

28.

Regulation of plasma ceramide levels with fatty acid oversupply: evidence that the liver detects and secretes de novo synthesised ceramide.

Watt MJ, Barnett AC, Bruce CR, Schenk S, Horowitz JF, Hoy AJ.

Diabetologia. 2012 Oct;55(10):2741-2746. doi: 10.1007/s00125-012-2649-3. Epub 2012 Jul 27.

29.

Lipid metabolism in skeletal muscle: generation of adaptive and maladaptive intracellular signals for cellular function.

Watt MJ, Hoy AJ.

Am J Physiol Endocrinol Metab. 2012 Jun 1;302(11):E1315-28. doi: 10.1152/ajpendo.00561.2011. Epub 2011 Dec 20. Review.

30.

Distinct roles of specific fatty acids in cellular processes: implications for interpreting and reporting experiments.

Watt MJ, Hoy AJ, Muoio DM, Coleman RA.

Am J Physiol Endocrinol Metab. 2012 Jan 1;302(1):E1-3. doi: 10.1152/ajpendo.00418.2011.

31.

The evolution of insulin resistance in muscle of the glucose infused rat.

Brandon AE, Hoy AJ, Wright LE, Turner N, Hegarty BD, Iseli TJ, Julia Xu X, Cooney GJ, Saha AK, Ruderman NB, Kraegen EW.

Arch Biochem Biophys. 2011 May 15;509(2):133-41. doi: 10.1016/j.abb.2011.03.008. Epub 2011 Mar 21.

32.

Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1β involves reductions in long-chain acyl-CoA levels and oxidative stress.

Wright LE, Brandon AE, Hoy AJ, Forsberg GB, Lelliott CJ, Reznick J, Löfgren L, Oscarsson J, Strömstedt M, Cooney GJ, Turner N.

Diabetologia. 2011 Jun;54(6):1417-26. doi: 10.1007/s00125-011-2068-x. Epub 2011 Feb 18.

PMID:
21331471
33.

Adipose triglyceride lipase-null mice are resistant to high-fat diet-induced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation.

Hoy AJ, Bruce CR, Turpin SM, Morris AJ, Febbraio MA, Watt MJ.

Endocrinology. 2011 Jan;152(1):48-58. doi: 10.1210/en.2010-0661. Epub 2010 Nov 24.

PMID:
21106876
34.

Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice.

Turpin SM, Hoy AJ, Brown RD, Rudaz CG, Honeyman J, Matzaris M, Watt MJ.

Diabetologia. 2011 Jan;54(1):146-56. doi: 10.1007/s00125-010-1895-5. Epub 2010 Sep 15.

PMID:
20842343
35.

Acute or chronic upregulation of mitochondrial fatty acid oxidation has no net effect on whole-body energy expenditure or adiposity.

Hoehn KL, Turner N, Swarbrick MM, Wilks D, Preston E, Phua Y, Joshi H, Furler SM, Larance M, Hegarty BD, Leslie SJ, Pickford R, Hoy AJ, Kraegen EW, James DE, Cooney GJ.

Cell Metab. 2010 Jan;11(1):70-6. doi: 10.1016/j.cmet.2009.11.008.

36.
37.

Insulin resistance is a cellular antioxidant defense mechanism.

Hoehn KL, Salmon AB, Hohnen-Behrens C, Turner N, Hoy AJ, Maghzal GJ, Stocker R, Van Remmen H, Kraegen EW, Cooney GJ, Richardson AR, James DE.

Proc Natl Acad Sci U S A. 2009 Oct 20;106(42):17787-92. doi: 10.1073/pnas.0902380106. Epub 2009 Sep 30.

38.

Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation.

Hoy AJ, Brandon AE, Turner N, Watt MJ, Bruce CR, Cooney GJ, Kraegen EW.

Am J Physiol Endocrinol Metab. 2009 Jul;297(1):E67-75. doi: 10.1152/ajpendo.90945.2008. Epub 2009 Apr 14.

39.

Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance.

Bruce CR, Hoy AJ, Turner N, Watt MJ, Allen TL, Carpenter K, Cooney GJ, Febbraio MA, Kraegen EW.

Diabetes. 2009 Mar;58(3):550-8. doi: 10.2337/db08-1078. Epub 2008 Dec 10.

40.

New insight into the mechanism by which acute physical exercise ameliorates insulin resistance.

Hoy AJ, Turner N.

J Physiol. 2008 May 1;586(9):2251-2. doi: 10.1113/jphysiol.2008.152991. Epub 2008 Mar 6. No abstract available.

41.

Adipose triglyceride lipase regulation of skeletal muscle lipid metabolism and insulin responsiveness.

Watt MJ, van Denderen BJ, Castelli LA, Bruce CR, Hoy AJ, Kraegen EW, Macaulay L, Kemp BE.

Mol Endocrinol. 2008 May;22(5):1200-12. doi: 10.1210/me.2007-0485. Epub 2008 Jan 17. Retraction in: Mol Endocrinol. 2010 Jun;24(6):1308.

42.

Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in Akt and AS160 phosphorylation.

Hoy AJ, Bruce CR, Cederberg A, Turner N, James DE, Cooney GJ, Kraegen EW.

Am J Physiol Endocrinol Metab. 2007 Nov;293(5):E1358-64. Epub 2007 Sep 4.

43.
44.

Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats.

Kraegen EW, Saha AK, Preston E, Wilks D, Hoy AJ, Cooney GJ, Ruderman NB.

Am J Physiol Endocrinol Metab. 2006 Mar;290(3):E471-9. Epub 2005 Oct 18.

45.

Dietary fish oil dose- and time-response effects on cardiac phospholipid fatty acid composition.

Owen AJ, Peter-Przyborowska BA, Hoy AJ, McLennan PL.

Lipids. 2004 Oct;39(10):955-61.

PMID:
15691017

Supplemental Content

Support Center