Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 240


Poxvirus-based vector systems and the potential for multi-valent and multi-pathogen vaccines.

Prow NA, Jimenez Martinez R, Hayball JD, Howley PM, Suhrbier A.

Expert Rev Vaccines. 2018 Oct;17(10):925-934. doi: 10.1080/14760584.2018.1522255. Epub 2018 Oct 9. Review.


Angelman syndrome-associated point mutations in the Zn2+-binding N-terminal (AZUL) domain of UBE3A ubiquitin ligase inhibit binding to the proteasome.

Kühnle S, Martínez-Noël G, Leclere F, Hayes SD, Harper JW, Howley PM.

J Biol Chem. 2018 Nov 23;293(47):18387-18399. doi: 10.1074/jbc.RA118.004653. Epub 2018 Sep 26.


The SMC5/6 Complex Interacts with the Papillomavirus E2 Protein and Influences Maintenance of Viral Episomal DNA.

Bentley P, Tan MJA, McBride AA, White EA, Howley PM.

J Virol. 2018 Jul 17;92(15). pii: e00356-18. doi: 10.1128/JVI.00356-18. Print 2018 Aug 1.


A vaccinia-based single vector construct multi-pathogen vaccine protects against both Zika and chikungunya viruses.

Prow NA, Liu L, Nakayama E, Cooper TH, Yan K, Eldi P, Hazlewood JE, Tang B, Le TT, Setoh YX, Khromykh AA, Hobson-Peters J, Diener KR, Howley PM, Hayball JD, Suhrbier A.

Nat Commun. 2018 Mar 26;9(1):1230. doi: 10.1038/s41467-018-03662-6.


Network Analysis of UBE3A/E6AP-Associated Proteins Provides Connections to Several Distinct Cellular Processes.

Martínez-Noël G, Luck K, Kühnle S, Desbuleux A, Szajner P, Galligan JT, Rodriguez D, Zheng L, Boyland K, Leclere F, Zhong Q, Hill DE, Vidal M, Howley PM.

J Mol Biol. 2018 Mar 30;430(7):1024-1050. doi: 10.1016/j.jmb.2018.01.021. Epub 2018 Feb 6.


The Human Papillomavirus E6 Oncoprotein Targets USP15 and TRIM25 To Suppress RIG-I-Mediated Innate Immune Signaling.

Chiang C, Pauli EK, Biryukov J, Feister KF, Meng M, White EA, Münger K, Howley PM, Meyers C, Gack MU.

J Virol. 2018 Feb 26;92(6). pii: e01737-17. doi: 10.1128/JVI.01737-17. Print 2018 Mar 15.


Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.

Cheng J, Park DE, Berrios C, White EA, Arora R, Yoon R, Branigan T, Xiao T, Westerling T, Federation A, Zeid R, Strober B, Swanson SK, Florens L, Bradner JE, Brown M, Howley PM, Padi M, Washburn MP, DeCaprio JA.

PLoS Pathog. 2017 Oct 13;13(10):e1006668. doi: 10.1371/journal.ppat.1006668. eCollection 2017 Oct.


Production of a Chikungunya Vaccine Using a CHO Cell and Attenuated Viral-Based Platform Technology.

Eldi P, Cooper TH, Liu L, Prow NA, Diener KR, Howley PM, Suhrbier A, Hayball JD.

Mol Ther. 2017 Oct 4;25(10):2332-2344. doi: 10.1016/j.ymthe.2017.06.017. Epub 2017 Jul 15.


Transient dominant host-range selection using Chinese hamster ovary cells to generate marker-free recombinant viral vectors from vaccinia virus.

Liu L, Cooper T, Eldi P, Garcia-Valtanen P, Diener KR, Howley PM, Hayball JD.

Biotechniques. 2017 Apr 1;62(4):183-187. doi: 10.2144/000114537.


High-Risk Human Papillomavirus E7 Proteins Target PTPN14 for Degradation.

White EA, Münger K, Howley PM.

MBio. 2016 Sep 20;7(5). pii: e01530-16. doi: 10.1128/mBio.01530-16.


Beta genus papillomaviruses and skin cancer.

Howley PM, Pfister HJ.

Virology. 2015 May;479-480:290-6. doi: 10.1016/j.virol.2015.02.004. Epub 2015 Feb 24. Review.


Papillomavirus E7 oncoproteins share functions with polyomavirus small T antigens.

White EA, Kramer RE, Hwang JH, Pores Fernando AT, Naetar N, Hahn WC, Roberts TM, Schaffhausen BS, Livingston DM, Howley PM.

J Virol. 2015 Mar;89(5):2857-65. doi: 10.1128/JVI.03282-14. Epub 2014 Dec 24.


Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3B.

Vieira VC, Leonard B, White EA, Starrett GJ, Temiz NA, Lorenz LD, Lee D, Soares MA, Lambert PF, Howley PM, Harris RS.

MBio. 2014 Dec 23;5(6). pii: e02234-14. doi: 10.1128/mBio.02234-14.


Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.

Galligan JT, Martinez-Noël G, Arndt V, Hayes S, Chittenden TW, Harper JW, Howley PM.

J Proteome Res. 2015 Feb 6;14(2):953-66. doi: 10.1021/pr501005v. Epub 2014 Dec 15.


From crescent to mature virion: vaccinia virus assembly and maturation.

Liu L, Cooper T, Howley PM, Hayball JD.

Viruses. 2014 Oct 7;6(10):3787-808. doi: 10.3390/v6103787. Review.


SMCX and components of the TIP60 complex contribute to E2 regulation of the HPV E6/E7 promoter.

Smith JA, Haberstroh FS, White EA, Livingston DM, DeCaprio JA, Howley PM.

Virology. 2014 Nov;468-470:311-321. doi: 10.1016/j.virol.2014.08.022. Epub 2014 Sep 16.


NSD3-NUT fusion oncoprotein in NUT midline carcinoma: implications for a novel oncogenic mechanism.

French CA, Rahman S, Walsh EM, Kühnle S, Grayson AR, Lemieux ME, Grunfeld N, Rubin BP, Antonescu CR, Zhang S, Venkatramani R, Dal Cin P, Howley PM.

Cancer Discov. 2014 Aug;4(8):928-41. doi: 10.1158/2159-8290.CD-14-0014. Epub 2014 May 29.


Genus beta human papillomavirus E6 proteins vary in their effects on the transactivation of p53 target genes.

White EA, Walther J, Javanbakht H, Howley PM.

J Virol. 2014 Aug;88(15):8201-12. doi: 10.1128/JVI.01197-14. Epub 2014 May 21.


Making an avipoxvirus encoding a tumor-associated antigen and a costimulatory molecule.

Howley PM, Diener KR, Hayball JD.

Methods Mol Biol. 2014;1139:407-27. doi: 10.1007/978-1-4939-0345-0_32.


Current and emerging immunotherapeutic approaches to treat and prevent peanut allergy.

Miller DS, Brown MP, Howley PM, Hayball JD.

Expert Rev Vaccines. 2012 Dec;11(12):1471-81. doi: 10.1586/erv.12.119. Review.


Proteomic approaches to the study of papillomavirus-host interactions.

White EA, Howley PM.

Virology. 2013 Jan 5;435(1):57-69. doi: 10.1016/j.virol.2012.09.046. Review.


Comprehensive analysis of host cellular interactions with human papillomavirus E6 proteins identifies new E6 binding partners and reflects viral diversity.

White EA, Kramer RE, Tan MJ, Hayes SD, Harper JW, Howley PM.

J Virol. 2012 Dec;86(24):13174-86. doi: 10.1128/JVI.02172-12. Epub 2012 Sep 26.


Identification and proteomic analysis of distinct UBE3A/E6AP protein complexes.

Martínez-Noël G, Galligan JT, Sowa ME, Arndt V, Overton TM, Harper JW, Howley PM.

Mol Cell Biol. 2012 Aug;32(15):3095-106. doi: 10.1128/MCB.00201-12. Epub 2012 May 29.


Cutaneous β-human papillomavirus E6 proteins bind Mastermind-like coactivators and repress Notch signaling.

Tan MJ, White EA, Sowa ME, Harper JW, Aster JC, Howley PM.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):E1473-80. doi: 10.1073/pnas.1205991109. Epub 2012 Apr 30.


Systematic identification of interactions between host cell proteins and E7 oncoproteins from diverse human papillomaviruses.

White EA, Sowa ME, Tan MJ, Jeudy S, Hayes SD, Santha S, Münger K, Harper JW, Howley PM.

Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):E260-7. doi: 10.1073/pnas.1116776109. Epub 2012 Jan 9.


The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.

Rahman S, Sowa ME, Ottinger M, Smith JA, Shi Y, Harper JW, Howley PM.

Mol Cell Biol. 2011 Jul;31(13):2641-52. doi: 10.1128/MCB.01341-10. Epub 2011 May 9.


NCoR1 mediates papillomavirus E8;E2C transcriptional repression.

Powell ML, Smith JA, Sowa ME, Harper JW, Iftner T, Stubenrauch F, Howley PM.

J Virol. 2010 May;84(9):4451-60. doi: 10.1128/JVI.02390-09. Epub 2010 Feb 24.


Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression.

Smith JA, White EA, Sowa ME, Powell ML, Ottinger M, Harper JW, Howley PM.

Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3752-7. doi: 10.1073/pnas.0914818107. Epub 2010 Feb 2.


Characterization of papillomavirus E1 helicase mutants defective for interaction with the SUMO-conjugating enzyme Ubc9.

Fradet-Turcotte A, Brault K, Titolo S, Howley PM, Archambault J.

Virology. 2009 Dec 20;395(2):190-201. doi: 10.1016/j.virol.2009.09.020.


Cell-type specific transcriptional activities among different papillomavirus long control regions and their regulation by E2.

Ottinger M, Smith JA, Schweiger MR, Robbins D, Powell ML, You J, Howley PM.

Virology. 2009 Dec 20;395(2):161-71. doi: 10.1016/j.virol.2009.09.027.


Regulation of aurora B expression by the bromodomain protein Brd4.

You J, Li Q, Wu C, Kim J, Ottinger M, Howley PM.

Mol Cell Biol. 2009 Sep;29(18):5094-103. doi: 10.1128/MCB.00299-09. Epub 2009 Jul 13.


Brd4 regulation of papillomavirus protein E2 stability.

Zheng G, Schweiger MR, Martinez-Noel G, Zheng L, Smith JA, Harper JW, Howley PM.

J Virol. 2009 Sep;83(17):8683-92. doi: 10.1128/JVI.00674-09. Epub 2009 Jun 24.


The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability.

Vos RM, Altreuter J, White EA, Howley PM.

J Virol. 2009 Sep;83(17):8885-92. doi: 10.1128/JVI.00605-09. Epub 2009 Jun 24.


Small DNA tumor viruses: large contributors to biomedical sciences.

Howley PM, Livingston DM.

Virology. 2009 Feb 20;384(2):256-9. doi: 10.1016/j.virol.2008.12.006. Epub 2009 Jan 10. Review.


CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.

Mulligan P, Westbrook TF, Ottinger M, Pavlova N, Chang B, Macia E, Shi YJ, Barretina J, Liu J, Howley PM, Elledge SJ, Shi Y.

Mol Cell. 2008 Dec 5;32(5):718-26. doi: 10.1016/j.molcel.2008.10.025.


Recombinant fowlpox virus elicits transient cytotoxic T cell responses due to suboptimal innate recognition and recruitment of T cell help.

Diener KR, Lousberg EL, Beukema EL, Yu A, Howley PM, Brown MP, Hayball JD.

Vaccine. 2008 Jul 4;26(29-30):3566-73. doi: 10.1016/j.vaccine.2008.05.015. Epub 2008 May 27.


Warts, cancer and ubiquitylation: lessons from the papillomaviruses.

Howley PM.

Trans Am Clin Climatol Assoc. 2006;117:113-26; discussion 126-7. Review.


Components of the ubiquitin-proteasome pathway compete for surfaces on Rad23 family proteins.

Goh AM, Walters KJ, Elsasser S, Verma R, Deshaies RJ, Finley D, Howley PM.

BMC Biochem. 2008 Jan 30;9:4. doi: 10.1186/1471-2091-9-4.


Brd4-independent transcriptional repression function of the papillomavirus e2 proteins.

Schweiger MR, Ottinger M, You J, Howley PM.

J Virol. 2007 Sep;81(18):9612-22. Epub 2007 Jul 11.


Bovine papillomavirus E7 oncoprotein inhibits anoikis.

DeMasi J, Chao MC, Kumar AS, Howley PM.

J Virol. 2007 Sep;81(17):9419-25. Epub 2007 Jun 27.


E6AP ubiquitin ligase mediates ubiquitylation and degradation of hepatitis C virus core protein.

Shirakura M, Murakami K, Ichimura T, Suzuki R, Shimoji T, Fukuda K, Abe K, Sato S, Fukasawa M, Yamakawa Y, Nishijima M, Moriishi K, Matsuura Y, Wakita T, Suzuki T, Howley PM, Miyamura T, Shoji I.

J Virol. 2007 Feb;81(3):1174-85. Epub 2006 Nov 15.


Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen interacts with bromodomain protein Brd4 on host mitotic chromosomes.

You J, Srinivasan V, Denis GV, Harrington WJ Jr, Ballestas ME, Kaye KM, Howley PM.

J Virol. 2006 Sep;80(18):8909-19.


Requirement of E7 oncoprotein for viability of HeLa cells.

Nishimura A, Nakahara T, Ueno T, Sasaki K, Yoshida S, Kyo S, Howley PM, Sakai H.

Microbes Infect. 2006 Apr;8(4):984-93. Epub 2006 Jan 17.


E6AP and calmodulin reciprocally regulate estrogen receptor stability.

Li L, Li Z, Howley PM, Sacks DB.

J Biol Chem. 2006 Jan 27;281(4):1978-85. Epub 2005 Nov 28.


Bovine papillomavirus E7 transformation function correlates with cellular p600 protein binding.

DeMasi J, Huh KW, Nakatani Y, Münger K, Howley PM.

Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11486-91. Epub 2005 Aug 4. Erratum in: Proc Natl Acad Sci U S A. 2006 Feb 21;103(8):3007.


Association of the human papillomavirus type 16 E7 oncoprotein with the 600-kDa retinoblastoma protein-associated factor, p600.

Huh KW, DeMasi J, Ogawa H, Nakatani Y, Howley PM, Münger K.

Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11492-7. Epub 2005 Aug 1.


Identification of TRAIL as an interferon regulatory factor 3 transcriptional target.

Kirshner JR, Karpova AY, Kops M, Howley PM.

J Virol. 2005 Jul;79(14):9320-4.

Supplemental Content

Loading ...
Support Center