Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 148

1.

The Endocannabinoid System and Oligodendrocytes in Health and Disease.

Ilyasov AA, Milligan CE, Pharr EP, Howlett AC.

Front Neurosci. 2018 Oct 26;12:733. doi: 10.3389/fnins.2018.00733. eCollection 2018. Review.

2.

In silico interaction analysis of cannabinoid receptor interacting protein 1b (CRIP1b) - CB1 cannabinoid receptor.

Singh P, Ganjiwale A, Howlett AC, Cowsik SM.

J Mol Graph Model. 2017 Oct;77:311-321. doi: 10.1016/j.jmgm.2017.09.006. Epub 2017 Sep 6.

3.

CB1 and CB2 Receptor Pharmacology.

Howlett AC, Abood ME.

Adv Pharmacol. 2017;80:169-206. doi: 10.1016/bs.apha.2017.03.007. Epub 2017 Jun 12. Review.

4.

Mouse Neuroblastoma CB1 Cannabinoid Receptor-Stimulated [35S]GTPɣS Binding: Total and Antibody-Targeted Gα Protein-Specific Scintillation Proximity Assays.

Eldeeb K, Leone-Kabler S, Howlett AC.

Methods Enzymol. 2017;593:1-21. doi: 10.1016/bs.mie.2017.06.028. Epub 2017 Jul 19.

PMID:
28750799
5.

Acute Depletion of D2 Receptors from the Rat Substantia Nigra Alters Dopamine Kinetics in the Dorsal Striatum and Drug Responsivity.

Budygin EA, Oleson EB, Lee YB, Blume LC, Bruno MJ, Howlett AC, Thompson AC, Bass CE.

Front Behav Neurosci. 2017 Jan 19;10:248. doi: 10.3389/fnbeh.2016.00248. eCollection 2016.

6.

Cannabinoid receptor interacting protein suppresses agonist-driven CB1 receptor internalization and regulates receptor replenishment in an agonist-biased manner.

Blume LC, Leone-Kabler S, Luessen DJ, Marrs GS, Lyons E, Bass CE, Chen R, Selley DE, Howlett AC.

J Neurochem. 2016 Nov;139(3):396-407. doi: 10.1111/jnc.13767. Epub 2016 Sep 26.

7.

RGS2 modulates the activity and internalization of dopamine D2 receptors in neuroblastoma N2A cells.

Luessen DJ, Hinshaw TP, Sun H, Howlett AC, Marrs G, McCool BA, Chen R.

Neuropharmacology. 2016 Nov;110(Pt A):297-307. doi: 10.1016/j.neuropharm.2016.08.009. Epub 2016 Aug 12.

8.

Medullary Endocannabinoids Contribute to the Differential Resting Baroreflex Sensitivity in Rats with Altered Brain Renin-Angiotensin System Expression.

Schaich CL, Grabenauer M, Thomas BF, Shaltout HA, Gallagher PE, Howlett AC, Diz DI.

Front Physiol. 2016 Jun 9;7:207. doi: 10.3389/fphys.2016.00207. eCollection 2016.

9.

CB1 cannabinoid receptor-mediated increases in cyclic AMP accumulation are correlated with reduced Gi/o function.

Eldeeb K, Leone-Kabler S, Howlett AC.

J Basic Clin Physiol Pharmacol. 2016 May 1;27(3):311-22. doi: 10.1515/jbcpp-2015-0096.

10.

Programs to Recruit and Retain a More Diverse Workforce in Biomedical Sciences Research.

Gwathmey TM, Tallant EA, Howlett AC, Diz DI.

J Best Pract Health Prof Divers. 2016 Spring;9(1):1188-1194.

11.

Gαi/o-dependent Ca(2+) mobilization and Gαq-dependent PKCα regulation of Ca(2+)-sensing receptor-mediated responses in N18TG2 neuroblastoma cells.

Sesay JS, Gyapong RN, Najafi LT, Kabler SL, Diz DI, Howlett AC, Awumey EM.

Neurochem Int. 2015 Nov;90:142-51. doi: 10.1016/j.neuint.2015.07.008. Epub 2015 Jul 16.

12.

Chronic baclofen desensitizes GABA(B)-mediated G-protein activation and stimulates phosphorylation of kinases in mesocorticolimbic rat brain.

Keegan BM, Beveridge TJ, Pezor JJ, Xiao R, Sexton T, Childers SR, Howlett AC.

Neuropharmacology. 2015 Aug;95:492-502. doi: 10.1016/j.neuropharm.2015.02.021. Epub 2015 Feb 25.

13.

Cannabinoid receptor-interacting protein 1a modulates CB1 receptor signaling and regulation.

Smith TH, Blume LC, Straiker A, Cox JO, David BG, McVoy JR, Sayers KW, Poklis JL, Abdullah RA, Egertová M, Chen CK, Mackie K, Elphick MR, Howlett AC, Selley DE.

Mol Pharmacol. 2015 Apr;87(4):747-65. doi: 10.1124/mol.114.096495. Epub 2015 Feb 5.

14.

Alterations in the Medullary Endocannabinoid System Contribute to Age-related Impairment of Baroreflex Sensitivity.

Schaich CL, Shaltout HA, Grabenauer M, Thomas BF, Gallagher PE, Howlett AC, Diz DI.

J Cardiovasc Pharmacol. 2015 May;65(5):473-9. doi: 10.1097/FJC.0000000000000216.

15.

Cannabinoid receptor interacting protein (CRIP1a) attenuates CB1R signaling in neuronal cells.

Blume LC, Eldeeb K, Bass CE, Selley DE, Howlett AC.

Cell Signal. 2015 Mar;27(3):716-726. doi: 10.1016/j.cellsig.2014.11.006. Epub 2014 Nov 17.

16.

Early phytocannabinoid chemistry to endocannabinoids and beyond.

Mechoulam R, Hanuš LO, Pertwee R, Howlett AC.

Nat Rev Neurosci. 2014 Nov;15(11):757-64. doi: 10.1038/nrn3811. Epub 2014 Oct 15. Review.

PMID:
25315390
17.

Acute and chronic systemic CB1 cannabinoid receptor blockade improves blood pressure regulation and metabolic profile in hypertensive (mRen2)27 rats.

Schaich CL, Shaltout HA, Brosnihan KB, Howlett AC, Diz DI.

Physiol Rep. 2014 Aug 28;2(8). pii: e12108. doi: 10.14814/phy2.12108. Print 2014 Aug 1.

18.

Increased angiotensin II contraction of the uterine artery at early gestation in a transgenic model of hypertensive pregnancy is reduced by inhibition of endocannabinoid hydrolysis.

Pulgar VM, Yamaleyeva LM, Varagic J, McGee CM, Bader M, Dechend R, Howlett AC, Brosnihan KB.

Hypertension. 2014 Sep;64(3):619-25. doi: 10.1161/HYPERTENSIONAHA.114.03633. Epub 2014 Jun 16.

19.

Regulation of gene expression by tobacco product preparations in cultured human dermal fibroblasts.

Malpass GE, Arimilli S, Prasad GL, Howlett AC.

Toxicol Appl Pharmacol. 2014 Sep 1;279(2):211-9. doi: 10.1016/j.taap.2014.06.001. Epub 2014 Jun 10.

20.

Amphetamine self-administration attenuates dopamine D2 autoreceptor function.

Calipari ES, Sun H, Eldeeb K, Luessen DJ, Feng X, Howlett AC, Jones SR, Chen R.

Neuropsychopharmacology. 2014 Jul;39(8):1833-42. doi: 10.1038/npp.2014.30. Epub 2014 Feb 11.

21.

Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate β-tubulin folding.

Tracy CM, Gray AJ, Cuéllar J, Shaw TS, Howlett AC, Taylor RM, Prince JT, Ahn NG, Valpuesta JM, Willardson BM.

J Biol Chem. 2014 Feb 14;289(7):4490-502. doi: 10.1074/jbc.M113.542159. Epub 2013 Dec 27.

22.

The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome.

Thomas G, Betters JL, Lord CC, Brown AL, Marshall S, Ferguson D, Sawyer J, Davis MA, Melchior JT, Blume LC, Howlett AC, Ivanova PT, Milne SB, Myers DS, Mrak I, Leber V, Heier C, Taschler U, Blankman JL, Cravatt BF, Lee RG, Crooke RM, Graham MJ, Zimmermann R, Brown HA, Brown JM.

Cell Rep. 2013 Oct 31;5(2):508-20. doi: 10.1016/j.celrep.2013.08.047. Epub 2013 Oct 3.

23.

Characterization of bladder function in a cannabinoid receptor type 2 knockout mouse in vivo and in vitro.

Campeau L, Füllhase C, Sawada N, Gratzke C, Hedlund P, Howlett AC, Andersson KE.

Neurourol Urodyn. 2014 Jun;33(5):566-70. doi: 10.1002/nau.22454. Epub 2013 Jul 3.

PMID:
23908133
24.

Complete artificial saliva alters expression of proinflammatory cytokines in human dermal fibroblasts.

Malpass GE, Arimilli S, Prasad GL, Howlett AC.

Toxicol Sci. 2013 Jul;134(1):18-25. doi: 10.1093/toxsci/kft103. Epub 2013 Apr 29.

25.

CB₁ cannabinoid receptors promote maximal FAK catalytic activity by stimulating cooperative signaling between receptor tyrosine kinases and integrins in neuronal cells.

Dalton GD, Peterson LJ, Howlett AC.

Cell Signal. 2013 Aug;25(8):1665-77. doi: 10.1016/j.cellsig.2013.03.020. Epub 2013 Apr 6.

26.

Hippocampal Gαq/₁₁ but not Gαo-coupled receptors are altered in aging.

McQuail JA, Davis KN, Miller F, Hampson RE, Deadwyler SA, Howlett AC, Nicolle MM.

Neuropharmacology. 2013 Jul;70:63-73. doi: 10.1016/j.neuropharm.2013.01.009. Epub 2013 Jan 21.

27.

Striatal CB1 and D2 receptors regulate expression of each other, CRIP1A and δ opioid systems.

Blume LC, Bass CE, Childers SR, Dalton GD, Roberts DC, Richardson JM, Xiao R, Selley DE, Howlett AC.

J Neurochem. 2013 Mar;124(6):808-20. doi: 10.1111/jnc.12139. Epub 2013 Jan 31.

28.

Effects of palmitoylation of Cys(415) in helix 8 of the CB(1) cannabinoid receptor on membrane localization and signalling.

Oddi S, Dainese E, Sandiford S, Fezza F, Lanuti M, Chiurchiù V, Totaro A, Catanzaro G, Barcaroli D, De Laurenzi V, Centonze D, Mukhopadhyay S, Selent J, Howlett AC, Maccarrone M.

Br J Pharmacol. 2012 Apr;165(8):2635-51. doi: 10.1111/j.1476-5381.2011.01658.x.

29.

Endocannabinoid tone versus constitutive activity of cannabinoid receptors.

Howlett AC, Reggio PH, Childers SR, Hampson RE, Ulloa NM, Deutsch DG.

Br J Pharmacol. 2011 Aug;163(7):1329-43. doi: 10.1111/j.1476-5381.2011.01364.x. Review.

30.
31.

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid receptors and their ligands: beyond CB₁ and CB₂.

Pertwee RG, Howlett AC, Abood ME, Alexander SP, Di Marzo V, Elphick MR, Greasley PJ, Hansen HS, Kunos G, Mackie K, Mechoulam R, Ross RA.

Pharmacol Rev. 2010 Dec;62(4):588-631. doi: 10.1124/pr.110.003004. Review.

32.

CB1 receptors modulate the intake of a sweetened-fat diet in response to μ-opioid receptor stimulation of the nucleus accumbens.

Skelly MJ, Guy EG, Howlett AC, Pratt WE.

Pharmacol Biochem Behav. 2010 Nov;97(1):144-51. doi: 10.1016/j.pbb.2010.05.024. Epub 2010 Jun 1.

33.

CB(1) cannabinoid receptors and their associated proteins.

Howlett AC, Blume LC, Dalton GD.

Curr Med Chem. 2010;17(14):1382-93. Review.

34.

Signal transduction via cannabinoid receptors.

Dalton GD, Bass CE, Van Horn CG, Howlett AC.

CNS Neurol Disord Drug Targets. 2009 Dec;8(6):422-31. Review.

35.

Role of molecular chaperones in G protein beta5/regulator of G protein signaling dimer assembly and G protein betagamma dimer specificity.

Howlett AC, Gray AJ, Hunter JM, Willardson BM.

J Biol Chem. 2009 Jun 12;284(24):16386-99. doi: 10.1074/jbc.M900800200. Epub 2009 Apr 17.

36.

Cannabinoid regulation of nitric oxide synthase I (nNOS) in neuronal cells.

Carney ST, Lloyd ML, MacKinnon SE, Newton DC, Jones JD, Howlett AC, Norford DC.

J Neuroimmune Pharmacol. 2009 Sep;4(3):338-49. doi: 10.1007/s11481-009-9153-7. Epub 2009 Apr 14.

37.

Gene expression of opioid and dopamine systems in mouse striatum: effects of CB1 receptors, age and sex.

Gerald TM, Howlett AC, Ward GR, Ho C, Franklin SO.

Psychopharmacology (Berl). 2008 Jul;198(4):497-508. doi: 10.1007/s00213-008-1141-8. Epub 2008 Apr 27.

38.

Binding mode prediction of conformationally restricted anandamide analogs within the CB1 receptor.

Padgett LW, Howlett AC, Shim JY.

J Mol Signal. 2008 Feb 26;3:5. doi: 10.1186/1750-2187-3-5.

39.

Endocannabinoids and reactive nitrogen and oxygen species in neuropathologies.

Howlett AC, Mukhopadhyay S, Norford DC.

J Neuroimmune Pharmacol. 2006 Sep;1(3):305-16. Epub 2006 Jun 24. Review.

PMID:
18040807
40.

CB1 cannabinoid receptor activity is modulated by the cannabinoid receptor interacting protein CRIP 1a.

Niehaus JL, Liu Y, Wallis KT, Egertová M, Bhartur SG, Mukhopadhyay S, Shi S, He H, Selley DE, Howlett AC, Elphick MR, Lewis DL.

Mol Pharmacol. 2007 Dec;72(6):1557-66. Epub 2007 Sep 25.

41.

Cannabinoid receptor-mediated translocation of NO-sensitive guanylyl cyclase and production of cyclic GMP in neuronal cells.

Jones JD, Carney ST, Vrana KE, Norford DC, Howlett AC.

Neuropharmacology. 2008 Jan;54(1):23-30. Epub 2007 Jul 12.

42.

Function of phosducin-like proteins in G protein signaling and chaperone-assisted protein folding.

Willardson BM, Howlett AC.

Cell Signal. 2007 Dec;19(12):2417-27. Epub 2007 Jun 28. Review.

43.

Helix 8 Leu in the CB1 cannabinoid receptor contributes to selective signal transduction mechanisms.

Anavi-Goffer S, Fleischer D, Hurst DP, Lynch DL, Barnett-Norris J, Shi S, Lewis DL, Mukhopadhyay S, Howlett AC, Reggio PH, Abood ME.

J Biol Chem. 2007 Aug 24;282(34):25100-13. Epub 2007 Jun 26.

44.

Glucocorticoids plus opioids up-regulate genes that influence neuronal function.

Ward GR, Franklin SO, Gerald TM, Dempsey KT, Clodfelter DE Jr, Krissinger DJ, Patel KM, Vrana KE, Howlett AC.

Cell Mol Neurobiol. 2007 Aug;27(5):651-60.

PMID:
17554624
45.

Unique helical conformation of the fourth cytoplasmic loop of the CB1 cannabinoid receptor in a negatively charged environment.

Grace CR, Cowsik SM, Shim JY, Welsh WJ, Howlett AC.

J Struct Biol. 2007 Sep;159(3):359-68. Epub 2007 Apr 20.

46.

Drama-based education to motivate participation in substance abuse prevention.

Stephens-Hernandez AB, Livingston JN, Dacons-Brock K, Craft HL, Cameron A, Franklin SO, Howlett AC.

Subst Abuse Treat Prev Policy. 2007 Apr 5;2:11.

47.

Anandamide-mediated CB1/CB2 cannabinoid receptor--independent nitric oxide production in rabbit aortic endothelial cells.

McCollum L, Howlett AC, Mukhopadhyay S.

J Pharmacol Exp Ther. 2007 Jun;321(3):930-7. Epub 2007 Mar 22.

48.

Ca(2+) mobilization through dorsal root ganglion Ca(2+)-sensing receptor stably expressed in HEK293 cells.

Awumey EM, Howlett AC, Putney JW Jr, Diz DI, Bukoski RD.

Am J Physiol Cell Physiol. 2007 May;292(5):C1895-905. Epub 2007 Jan 31.

49.

Lipopolysaccharide and cyclic AMP regulation of CB(2) cannabinoid receptor levels in rat brain and mouse RAW 264.7 macrophages.

Mukhopadhyay S, Das S, Williams EA, Moore D, Jones JD, Zahm DS, Ndengele MM, Lechner AJ, Howlett AC.

J Neuroimmunol. 2006 Dec;181(1-2):82-92. Epub 2006 Oct 10.

PMID:
17045344
50.

WIN55212-2 docking to the CB1 cannabinoid receptor and multiple pathways for conformational induction.

Shim JY, Howlett AC.

J Chem Inf Model. 2006 May-Jun;46(3):1286-300.

PMID:
16711748

Supplemental Content

Loading ...
Support Center