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Items: 24


Differences in Steap3 expression are a mechanism of genetic variation of RBC storage and oxidative damage in mice.

Howie HL, Hay AM, de Wolski K, Waterman H, Lebedev J, Fu X, Culp-Hill R, D'Alessandro A, Gorham JD, Ranson MS, Roback JD, Thomson PC, Zimring JC.

Blood Adv. 2019 Aug 13;3(15):2272-2285. doi: 10.1182/bloodadvances.2019000605.


Murine models of autoimmune hemolytic anemia.

Howie HL, Hudson KE.

Curr Opin Hematol. 2018 Nov;25(6):473-481. doi: 10.1097/MOH.0000000000000459. Review.


Identification of IgG3-specific epitope that remedies problem in diagnostic IgG subclass determination due to human genetic variation.

Howie HL, Wang X, Kapp L, Lebedev JN, Zimring JC.

J Clin Pathol. 2018 Jun;71(6):559-561. doi: 10.1136/jclinpath-2018-205001. Epub 2018 Mar 17.


Common murine immunoglobulin detection reagents have diminished reactivity with IgG3 - A vulnerability to misinterpretation.

Howie HL, Wang X, Kapp L, Lebedev J, Hudson KE, Zimring JC.

J Immunol Methods. 2018 Apr;455:10-13. doi: 10.1016/j.jim.2018.01.011. Epub 2018 Jan 31.


Innate B-1 B Cells Are Not Enriched in Red Blood Cell Autoimmune Mice: Importance of B Cell Receptor Transgenic Selection.

Richards AL, Howie HL, Kapp LM, Hendrickson JE, Zimring JC, Hudson KE.

Front Immunol. 2017 Nov 3;8:1366. doi: 10.3389/fimmu.2017.01366. eCollection 2017.


Murine red blood cells from genetically distinct donors cross-regulate when stored together.

Hay A, Howie HL, Waterman HR, de Wolski K, Zimring JC.

Transfusion. 2017 Nov;57(11):2657-2664. doi: 10.1111/trf.14313. Epub 2017 Sep 16.


Errors in data interpretation from genetic variation of human analytes.

Howie HL, Delaney M, Wang X, Er LS, Kapp L, Lebedev JN, Zimring JC.

JCI Insight. 2017 Jul 6;2(13). pii: 94532. doi: 10.1172/jci.insight.94532. eCollection 2017 Jul 6.


Affinity of human IgG subclasses to mouse Fc gamma receptors.

Dekkers G, Bentlage AEH, Stegmann TC, Howie HL, Lissenberg-Thunnissen S, Zimring J, Rispens T, Vidarsson G.

MAbs. 2017 Jul;9(5):767-773. doi: 10.1080/19420862.2017.1323159. Epub 2017 May 2.


Regulatory T Cells Are Dispensable for Tolerance to RBC Antigens.

Richards AL, Kapp LM, Wang X, Howie HL, Hudson KE.

Front Immunol. 2016 Sep 19;7:348. eCollection 2016.


Serological blind spots for variants of human IgG3 and IgG4 by a commonly used anti-immunoglobulin reagent.

Howie HL, Delaney M, Wang X, Er LS, Vidarsson G, Stegmann TC, Kapp L, Lebedev JN, Wu Y, AuBuchon JP, Zimring JC.

Transfusion. 2016 Dec;56(12):2953-2962. doi: 10.1111/trf.13812. Epub 2016 Sep 16.


Metabolic pathways that correlate with post-transfusion circulation of stored murine red blood cells.

de Wolski K, Fu X, Dumont LJ, Roback JD, Waterman H, Odem-Davis K, Howie HL, Zimring JC.

Haematologica. 2016 May;101(5):578-86. doi: 10.3324/haematol.2015.139139. Epub 2016 Feb 26.


Analysis of 24-h recovery of transfused stored RBCs in recipient mice of distinct genetic backgrounds.

Waterman HR, Kapp LM, Howie HL, Hod EA, Spitalnik SL, Zimring JC.

Vox Sang. 2015 Aug;109(2):148-54. doi: 10.1111/vox.12270. Epub 2015 Jun 5.


β-HPV 5 and 8 E6 disrupt homology dependent double strand break repair by attenuating BRCA1 and BRCA2 expression and foci formation.

Wallace NA, Robinson K, Howie HL, Galloway DA.

PLoS Pathog. 2015 Mar 24;11(3):e1004687. doi: 10.1371/journal.ppat.1004687. eCollection 2015 Mar.


HPV 5 and 8 E6 expression reduces ATM protein levels and attenuates LINE-1 retrotransposition.

Wallace NA, Gasior SL, Faber ZJ, Howie HL, Deininger PL, Galloway DA.

Virology. 2013 Aug 15;443(1):69-79. doi: 10.1016/j.virol.2013.04.022. Epub 2013 May 23.


HPV 5 and 8 E6 abrogate ATR activity resulting in increased persistence of UVB induced DNA damage.

Wallace NA, Robinson K, Howie HL, Galloway DA.

PLoS Pathog. 2012;8(7):e1002807. doi: 10.1371/journal.ppat.1002807. Epub 2012 Jul 12.


Functional genomics identifies therapeutic targets for MYC-driven cancer.

Toyoshima M, Howie HL, Imakura M, Walsh RM, Annis JE, Chang AN, Frazier J, Chau BN, Loboda A, Linsley PS, Cleary MA, Park JR, Grandori C.

Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9545-50. doi: 10.1073/pnas.1121119109. Epub 2012 May 23.


MYC-driven tumorigenesis is inhibited by WRN syndrome gene deficiency.

Moser R, Toyoshima M, Robinson K, Gurley KE, Howie HL, Davison J, Morgan M, Kemp CJ, Grandori C.

Mol Cancer Res. 2012 Apr;10(4):535-45. doi: 10.1158/1541-7786.MCR-11-0508. Epub 2012 Feb 1.


Beta-HPV 5 and 8 E6 promote p300 degradation by blocking AKT/p300 association.

Howie HL, Koop JI, Weese J, Robinson K, Wipf G, Kim L, Galloway DA.

PLoS Pathog. 2011 Aug;7(8):e1002211. doi: 10.1371/journal.ppat.1002211. Epub 2011 Aug 25.


Papillomavirus E6 proteins.

Howie HL, Katzenellenbogen RA, Galloway DA.

Virology. 2009 Feb 20;384(2):324-34. doi: 10.1016/j.virol.2008.11.017. Epub 2008 Dec 10. Review.


E6 proteins from multiple human betapapillomavirus types degrade Bak and protect keratinocytes from apoptosis after UVB irradiation.

Underbrink MP, Howie HL, Bedard KM, Koop JI, Galloway DA.

J Virol. 2008 Nov;82(21):10408-17. doi: 10.1128/JVI.00902-08. Epub 2008 Aug 20.


Extracellular signal-regulated kinase activation by Neisseria gonorrhoeae downregulates epithelial cell proapoptotic proteins Bad and Bim.

Howie HL, Shiflett SL, So M.

Infect Immun. 2008 Jun;76(6):2715-21. doi: 10.1128/IAI.00153-08. Epub 2008 Apr 7.


The E6 oncoproteins from human betapapillomaviruses differentially activate telomerase through an E6AP-dependent mechanism and prolong the lifespan of primary keratinocytes.

Bedard KM, Underbrink MP, Howie HL, Galloway DA.

J Virol. 2008 Apr;82(8):3894-902. doi: 10.1128/JVI.01818-07. Epub 2008 Feb 6.


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