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Items: 1 to 50 of 799

1.

Actinomycin D and Telmisartan Combination Targets Lung Cancer Stem Cells Through the Wnt/Beta Catenin Pathway.

Green R, Howell M, Khalil R, Nair R, Yan J, Foran E, Katiri S, Banerjee J, Singh M, Bharadwaj S, Mohapatra SS, Mohapatra S.

Sci Rep. 2019 Dec 3;9(1):18177. doi: 10.1038/s41598-019-54266-z.

2.

Targeting the Janus Kinase Family in Autoimmune Skin Diseases.

Howell MD, Kuo FI, Smith PA.

Front Immunol. 2019 Oct 9;10:2342. doi: 10.3389/fimmu.2019.02342. eCollection 2019. Review.

3.

Treatment of atopic dermatitis with ruxolitinib cream (JAK1/JAK2 inhibitor) or triamcinolone cream.

Kim BS, Howell MD, Sun K, Papp K, Nasir A, Kuligowski ME; INCB 18424-206 Study Investigators.

J Allergy Clin Immunol. 2019 Oct 17. pii: S0091-6749(19)31326-0. doi: 10.1016/j.jaci.2019.08.042. [Epub ahead of print]

4.

A CRISPR platform for targeted in vivo screens identifies Toxoplasma gondii virulence factors in mice.

Young J, Dominicus C, Wagener J, Butterworth S, Ye X, Kelly G, Ordan M, Saunders B, Instrell R, Howell M, Stewart A, Treeck M.

Nat Commun. 2019 Sep 3;10(1):3963. doi: 10.1038/s41467-019-11855-w.

5.

Atopic Dermatitis Endotypes Based on Allergen Sensitization, Reactivity to Staphylococcus aureus Antigens, and Underlying Systemic Inflammation.

Leonard A, Wang J, Yu L, Liu H, Estrada Y, Greenlees L, McPhee R, Ruzin A, Guttman-Yassky E, Howell MD.

J Allergy Clin Immunol Pract. 2019 Aug 17. pii: S2213-2198(19)30719-6. doi: 10.1016/j.jaip.2019.08.013. [Epub ahead of print]

PMID:
31430591
6.

Identifying critically important vascular access outcomes for trials in haemodialysis: an international survey with patients, caregivers and health professionals.

Viecelli AK, Howell M, Tong A, Teixeira-Pinto A, O'Lone E, Ju A, Craig JC, Hooi LS, Lee T, Lok CE, Polkinghorne KR, Quinn RR, Vachharajani TJ, Vanholder R, Zuo L, Tordoir J, Pecoits-Filho R, Yuo T, Kopperschmidt P, Smith R, Irish AB, Mori TA, Pascoe EM, Johnson DW, Hawley CM.

Nephrol Dial Transplant. 2019 Aug 1. pii: gfz148. doi: 10.1093/ndt/gfz148. [Epub ahead of print]

PMID:
31369099
7.

Identifying dimensions of fatigue in haemodialysis important to patients, caregivers and health professionals: An international survey.

Ju A, Unruh M, Davison SN, Dapueto J, Dew MA, Fluck R, Germain M, Jassal SV, Obrador G, O'Donoghue D, Howell M, O'Lone E, Shen JI, Craig JC, Tong A; SONG-HD Initiative.

Nephrology (Carlton). 2019 Jul 25. doi: 10.1111/nep.13638. [Epub ahead of print]

PMID:
31347227
8.

Thromboembolic Risk of 4-Factor Prothrombin Complex Concentrate versus Fresh Frozen Plasma for Urgent Warfarin Reversal in the Emergency Department.

Maguire M, Fuh L, Goldstein JN, Marshall AL, Levine M, Howell ML, Parry BA, Rosovsky R, Hayes BD.

West J Emerg Med. 2019 Jul;20(4):619-625. doi: 10.5811/westjem.2019.4.41649. Epub 2019 Jun 11.

9.

Patient-specific cancer genes contribute to recurrently perturbed pathways and establish therapeutic vulnerabilities in esophageal adenocarcinoma.

Mourikis TP, Benedetti L, Foxall E, Temelkovski D, Nulsen J, Perner J, Cereda M, Lagergren J, Howell M, Yau C, Fitzgerald RC, Scaffidi P; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, Ciccarelli FD.

Nat Commun. 2019 Jul 15;10(1):3101. doi: 10.1038/s41467-019-10898-3.

10.

What do community health workers want? Findings of a discrete choice experiment among Accredited Social Health Activists (ASHAs) in India.

Abdel-All M, Angell B, Jan S, Howell M, Howard K, Abimbola S, Joshi R.

BMJ Glob Health. 2019 May 31;4(3):e001509. doi: 10.1136/bmjgh-2019-001509. eCollection 2019.

11.

Use of progression criteria to support monitoring and commissioning decision making of public health services: lessons from Better Start Bradford.

Bryant M, Dharni N, Dickerson J, Willan K, McEachan R, Duffy J, Howell M.

BMC Public Health. 2019 Jun 27;19(1):835. doi: 10.1186/s12889-019-7149-7.

12.

An international Delphi survey helped develop consensus-based core outcome domains for trials in peritoneal dialysis.

Manera KE, Tong A, Craig JC, Shen J, Jesudason S, Cho Y, Sautenet B, Teixeira-Pinto A, Howell M, Wang AY, Brown EA, Brunier G, Perl J, Dong J, Wilkie M, Mehrotra R, Pecoits-Filho R, Naicker S, Dunning T, Scholes-Robertson N, Johnson DW.

Kidney Int. 2019 Sep;96(3):699-710. doi: 10.1016/j.kint.2019.03.015. Epub 2019 Mar 29.

PMID:
31200941
13.

Understanding barriers to timely identification of infants at risk of neonatal opiate withdrawal syndrome.

Howell MP, Smith AM, Lindsay EB, Drury SS.

J Matern Fetal Neonatal Med. 2019 Jun 14:1-6. doi: 10.1080/14767058.2019.1627316. [Epub ahead of print]

PMID:
31195865
14.

Authors' Reply to Hussain et al.: "Cost Effectiveness of Dialysis Modalities: A Systematic Review of Economic Evaluations".

Howell M, Walker R, Howard K.

Appl Health Econ Health Policy. 2019 Aug;17(4):571-572. doi: 10.1007/s40258-019-00486-3. No abstract available.

PMID:
31175562
15.

Standardized Outcomes in Nephrology-Glomerular Disease (SONG-GD): establishing a core outcome set for trials in patients with glomerular disease.

Carter SA, Lightstone L, Cattran D, Bagga A, Barbour SJ, Barratt J, Boletis J, Caster D, Coppo R, Fervenza FC, Floege J, Hladunewich M, Hogan JJ, Kitching AR, Lafayette R, Malvar A, Radhakrishnan J, Rovin BH, Zhang H, Gutman T, Howell M, Logeman C, Shen JI, Teixeira-Pinto A, Alexander SI, Cho Y, Craig JC, Harris D, Johnson DW, Kerr PG, Ryan J, Viecelli AK, Wang AY, Wilkie M, Scholes-Robertson N, Tong A; SONG-GD Initiative.

Kidney Int. 2019 Jun;95(6):1280-1283. doi: 10.1016/j.kint.2019.01.047. No abstract available.

PMID:
31122702
16.

Violence Prevention: Technology-Enabled Therapeutic Intervention.

Burkoski V, Farshait N, Yoon J, Clancy PV, Fernandes K, Howell MR, Solomon S, Orrico ME, Collins BE.

Nurs Leadersh (Tor Ont). 2019 May;32(SP):58-70. doi: 10.12927/cjnl.2019.25814.

PMID:
31099747
17.

Principles and strategies for involving patients in research in chronic kidney disease: report from national workshops.

Gutman T, Tong A, Howell M, Dansie K, Hawley CM, Craig JC, Jesudason S, Chapman JR, Johnson DW, Murphy L, Reidlinger D, Crowe S, Duncanson E, Muthuramalingam S, Scholes-Robertson N, Williamson A, McDonald S; Better Evidence and Translation in Chronic Kidney Disease (BEAT-CKD) Workshop Investigators .

Nephrol Dial Transplant. 2019 May 15. pii: gfz076. doi: 10.1093/ndt/gfz076. [Epub ahead of print]

PMID:
31093667
18.

Functional characterization of a subtilisin-like serine protease from Vibrio cholerae.

Howell M, Dumitrescu DG, Blankenship LR, Herkert D, Hatzios SK.

J Biol Chem. 2019 Jun 21;294(25):9888-9900. doi: 10.1074/jbc.RA119.007745. Epub 2019 May 10.

PMID:
31076508
19.

Targeted, structured text messaging to improve dietary and lifestyle behaviours for people on maintenance haemodialysis (KIDNEYTEXT): study protocol for a randomised controlled trial.

Stevenson J, Campbell KL, Brown M, Craig J, Howard K, Howell M, Khalid R, Sud K, Teixeira-Pinto A, Thiagalingam A, Tong A, Chow C, Lee VW.

BMJ Open. 2019 May 5;9(5):e023545. doi: 10.1136/bmjopen-2018-023545.

20.

An Essential Regulator of Bacterial Division Links FtsZ to Cell Wall Synthase Activation.

Lariviere PJ, Mahone CR, Santiago-Collazo G, Howell M, Daitch AK, Zeinert R, Chien P, Brown PJB, Goley ED.

Curr Biol. 2019 May 6;29(9):1460-1470.e4. doi: 10.1016/j.cub.2019.03.066. Epub 2019 Apr 25.

PMID:
31031115
21.

p62-mediated Selective autophagy endows virus-transformed cells with insusceptibility to DNA damage under oxidative stress.

Wang L, Howell MEA, Sparks-Wallace A, Hawkins C, Nicksic CA, Kohne C, Hall KH, Moorman JP, Yao ZQ, Ning S.

PLoS Pathog. 2019 Apr 24;15(4):e1007541. doi: 10.1371/journal.ppat.1007541. eCollection 2019 Apr.

22.

Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study.

Rothwell DG, Ayub M, Cook N, Thistlethwaite F, Carter L, Dean E, Smith N, Villa S, Dransfield J, Clipson A, White D, Nessa K, Ferdous S, Howell M, Gupta A, Kilerci B, Mohan S, Frese K, Gulati S, Miller C, Jordan A, Eaton H, Hickson N, O'Brien C, Graham D, Kelly C, Aruketty S, Metcalf R, Chiramel J, Tinsley N, Vickers AJ, Kurup R, Frost H, Stevenson J, Southam S, Landers D, Wallace A, Marais R, Hughes AM, Brady G, Dive C, Krebs MG.

Nat Med. 2019 May;25(5):738-743. doi: 10.1038/s41591-019-0380-z. Epub 2019 Apr 22.

PMID:
31011204
23.

Validation and Invalidation of Chemical Probes for the Human N-myristoyltransferases.

Kallemeijn WW, Lueg GA, Faronato M, Hadavizadeh K, Goya Grocin A, Song OR, Howell M, Calado DP, Tate EW.

Cell Chem Biol. 2019 Jun 20;26(6):892-900.e4. doi: 10.1016/j.chembiol.2019.03.006. Epub 2019 Apr 18.

24.

NAV-KIDS2 trial: protocol for a multi-centre, staggered randomised controlled trial of a patient navigator intervention in children with chronic kidney disease.

van Zwieten A, Caldwell P, Howard K, Tong A, Craig JC, Alexander S, Howell M, Armando TP, Hawley C, Jesudason S, Walker A, Mackie F, Kennedy S, McTaggart S, McCarthy H, Carter S, Kim S, Crafter S, Woodleigh R, Guha C, Wong G.

BMC Nephrol. 2019 Apr 18;20(1):134. doi: 10.1186/s12882-019-1325-y.

25.

Measuring the quality of inpatient specialist consultation in the intensive care unit: Nursing and family experiences of communication.

Roche SD, Reichheld AM, Demosthenes N, Johansson AC, Howell MD, Cocchi MN, Landon BE, Stevens JP.

PLoS One. 2019 Apr 11;14(4):e0214918. doi: 10.1371/journal.pone.0214918. eCollection 2019.

26.

Student Understanding of DNA Structure-Function Relationships Improves from Using 3D Learning Modules with Dynamic 3D Printed Models.

Howell ME, Booth CS, Sikich SM, Helikar T, Roston RL, Couch BA, van Dijk K.

Biochem Mol Biol Educ. 2019 May;47(3):303-317. doi: 10.1002/bmb.21234. Epub 2019 Mar 21.

PMID:
30897273
27.

Integrating research and system-wide practice in public health: lessons learnt from Better Start Bradford.

Dickerson J, Bird PK, Bryant M, Dharni N, Bridges S, Willan K, Ahern S, Dunn A, Nielsen D, Uphoff EP, Bywater T, Bowyer-Crane C, Sahota P, Small N, Howell M, Thornton G, Pickett KE, McEachan RRC, Wright J; Better Start Bradford; Better Start Bradford Innovation Hub.

BMC Public Health. 2019 Mar 4;19(1):260. doi: 10.1186/s12889-019-6554-2.

28.

Extended Treatment with Glial Cell Line-Derived Neurotrophic Factor in Parkinson's Disease.

Whone AL, Boca M, Luz M, Woolley M, Mooney L, Dharia S, Broadfoot J, Cronin D, Schroers C, Barua NU, Longpre L, Barclay CL, Boiko C, Johnson GA, Fibiger HC, Harrison R, Lewis O, Pritchard G, Howell M, Irving C, Johnson D, Kinch S, Marshall C, Lawrence AD, Blinder S, Sossi V, Stoessl AJ, Skinner P, Mohr E, Gill SS.

J Parkinsons Dis. 2019;9(2):301-313. doi: 10.3233/JPD-191576.

29.

Randomized trial of intermittent intraputamenal glial cell line-derived neurotrophic factor in Parkinson's disease.

Whone A, Luz M, Boca M, Woolley M, Mooney L, Dharia S, Broadfoot J, Cronin D, Schroers C, Barua NU, Longpre L, Barclay CL, Boiko C, Johnson GA, Fibiger HC, Harrison R, Lewis O, Pritchard G, Howell M, Irving C, Johnson D, Kinch S, Marshall C, Lawrence AD, Blinder S, Sossi V, Stoessl AJ, Skinner P, Mohr E, Gill SS.

Brain. 2019 Mar 1;142(3):512-525. doi: 10.1093/brain/awz023.

30.

MDH1 and MPP7 Regulate Autophagy in Pancreatic Ductal Adenocarcinoma.

New M, Van Acker T, Sakamaki JI, Jiang M, Saunders RE, Long J, Wang VM, Behrens A, Cerveira J, Sudhakar P, Korcsmaros T, Jefferies HBJ, Ryan KM, Howell M, Tooze SA.

Cancer Res. 2019 Apr 15;79(8):1884-1898. doi: 10.1158/0008-5472.CAN-18-2553. Epub 2019 Feb 14.

31.

Defining host-pathogen interactions employing an artificial intelligence workflow.

Fisch D, Yakimovich A, Clough B, Wright J, Bunyan M, Howell M, Mercer J, Frickel E.

Elife. 2019 Feb 12;8. pii: e40560. doi: 10.7554/eLife.40560.

32.

Cost Effectiveness of Dialysis Modalities: A Systematic Review of Economic Evaluations.

Howell M, Walker RC, Howard K.

Appl Health Econ Health Policy. 2019 Jun;17(3):315-330. doi: 10.1007/s40258-018-00455-2. Review.

PMID:
30714086
33.

'Knowledge is power': A framework for partnering with consumers in developing and delivering a scientific meeting in nephrology.

Duncanson E, Dansie K, Gutman T, Tong A, Howell M, Jesudason S, Reidlinger D, Williamson A, Scholes-Robertson N, Murphy L, Hawley CM, Craig JC, Johnson DW, McDonald S.

Nephrology (Carlton). 2019 Jan 29. doi: 10.1111/nep.13570. [Epub ahead of print]

PMID:
30693601
34.

Agrobacterium tumefaciens divisome proteins regulate the transition from polar growth to cell division.

Howell M, Aliashkevich A, Sundararajan K, Daniel JJ, Lariviere PJ, Goley ED, Cava F, Brown PJB.

Mol Microbiol. 2019 Apr;111(4):1074-1092. doi: 10.1111/mmi.14212. Epub 2019 Mar 4.

PMID:
30693575
35.

Patient-reported outcome measures for life participation in kidney transplantation: A systematic review.

Ju A, Chow BY, Ralph AF, Howell M, Josephson MA, Ahn C, Butt Z, Dobbels F, Fowler K, Jowsey-Gregoire S, Jha V, Locke JE, Tan JC, Taylor Q, Rutherford C, Craig JC, Tong A.

Am J Transplant. 2019 Aug;19(8):2306-2317. doi: 10.1111/ajt.15267. Epub 2019 Feb 28.

PMID:
30664327
36.

Identifying patient-important outcomes in polycystic kidney disease: An international nominal group technique study.

Cho Y, Sautenet B, Gutman T, Rangan G, Craig JC, Ong AC, Chapman A, Ahn C, Coolican H, Kao JT, Gansevoort R, Perrone RD, Harris T, Torres V, Pei Y, Kerr PG, Ryan J, Johnson DW, Viecelli AK, Geneste C, Kim H, Kim Y, Oh YK, Teixeira-Pinto A, Logeman C, Howell M, Ju A, Manera KE, Tong A.

Nephrology (Carlton). 2019 Dec;24(12):1214-1224. doi: 10.1111/nep.13566. Epub 2019 May 2.

PMID:
30663163
37.

Improving Benefit-harm Assessment of Therapies from the Patient Perspective: OMERACT Premeeting Toward Consensus on Core Sets for Randomized Controlled Trials.

Andersen KM, Cheah JTL, March L, Bartlett SJ, Beaton D, Bingham CO 3rd, Brooks PM, Christensen R, Conaghan PG, D'Agostino MA, de Wit M, Dueck AC, Goodman SM, Grosskleg S, Hill CL, Howell M, Mackie SL, Richards B, Shea B, Singh JA, Strand V, Tugwell P, Wells GA, Simon LS.

J Rheumatol. 2019 Aug;46(8):1053-1058. doi: 10.3899/jrheum.181123. Epub 2019 Jan 15.

PMID:
30647191
38.

Calcific Insertional Achilles Tendinopathy-Achilles Repair With Flexor Hallucis Longus Tendon Transfer: Case Series and Surgical Technique.

Howell MA, McConn TP, Saltrick KR, Catanzariti AR.

J Foot Ankle Surg. 2019 Mar;58(2):236-242. doi: 10.1053/j.jfas.2018.08.021. Epub 2019 Jan 3.

PMID:
30612865
39.

Identification and Validation of Novel Autophagy Regulators Using an Endogenous Readout siGENOME Screen.

New M, Van Acker T, Jiang M, Saunders R, Long JS, Sakamaki JI, Ryan KM, Howell M, Tooze SA.

Methods Mol Biol. 2019;1880:359-374. doi: 10.1007/978-1-4939-8873-0_24.

PMID:
30610710
40.

A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest.

Deiss K, Lockwood N, Howell M, Segeren HA, Saunders RE, Chakravarty P, Soliman TN, Martini S, Rocha N, Semple R, Zalmas LP, Parker PJ.

Nucleic Acids Res. 2019 Apr 8;47(6):2906-2921. doi: 10.1093/nar/gky1295.

41.

Ensuring Fairness in Machine Learning to Advance Health Equity.

Rajkomar A, Hardt M, Howell MD, Corrado G, Chin MH.

Ann Intern Med. 2018 Dec 18;169(12):866-872. doi: 10.7326/M18-1990. Epub 2018 Dec 4.

42.

How to Evaluate Interventions for the Treatment and Care of Patients With Acute Kidney Injury.

Howell M.

Kidney Int Rep. 2018 Sep 21;3(6):1255-1257. doi: 10.1016/j.ekir.2018.09.009. eCollection 2018 Nov. No abstract available.

43.

The Dynamics of TGF-β Signaling Are Dictated by Receptor Trafficking via the ESCRT Machinery.

Miller DSJ, Bloxham RD, Jiang M, Gori I, Saunders RE, Das D, Chakravarty P, Howell M, Hill CS.

Cell Rep. 2018 Nov 13;25(7):1841-1855.e5. doi: 10.1016/j.celrep.2018.10.056.

44.

Bridging the Gap: Interdepartmental Quality Improvement and Patient Safety Curriculum Created by Hospital Leaders, Faculty, and Trainees.

Miller ME, Patel A, Schindler N, Hirsch K, Ming M, Weber S, Turner P, Howell MD, Arora VM, Oyler JL.

J Grad Med Educ. 2018 Oct;10(5):566-572. doi: 10.4300/JGME-D-18-00060.1.

45.

Association Between Room Location and Adverse Outcomes in Hospitalized Patients.

Mayampurath A, Ward C, Fahrenbach J, LaFond C, Howell M, Churpek MM.

HERD. 2019 Apr;12(2):21-29. doi: 10.1177/1937586718806702. Epub 2018 Oct 31.

PMID:
30380918
46.

Visualizing the Invisible: A Guide to Designing, Printing, and Incorporating Dynamic 3D Molecular Models to Teach Structure-Function Relationships.

Howell ME, van Dijk K, Booth CS, Helikar T, Couch BA, Roston RL.

J Microbiol Biol Educ. 2018 Oct 31;19(3). pii: 19.3.100. doi: 10.1128/jmbe.v19i3.1663. eCollection 2018. No abstract available.

47.

Establishing a Core Outcome Measure for Life Participation: A Standardized Outcomes in Nephrology-kidney Transplantation Consensus Workshop Report.

Ju A, Josephson MA, Butt Z, Jowsey-Gregoire S, Tan J, Taylor Q, Fowler K, Dobbels F, Caskey F, Jha V, Locke J, Knoll G, Ahn C, Hanson CS, Sautenet B, Manera K, Craig JC, Howell M, Rutherford C, Tong A, Harden P, Hawley C, Holdaas H, Israni A, Jesse M, Kane B, Kanellis J, Kiberd B, Kim J, Larsen C, Leichtman A, Lentine K, Malone A, Mannon R, Oberbauer R, Patzer R, Peipert JD, Phan HA, Poggio E, Reed R, Scandling J, Tang I, Watson C, Contrares D, Contreras P, Cross D, Juodvalkis E, Koide D, Koide J, Kozarewicz A, Kozarewicz L, Kozarewicz R, Koritala A, Lisiecki E, Lipuma C, Lyman M, Mueller R, Mueller G, Noble L, Nolan N, Nolan S, Thomas J, Urbancyzk L, Zerante J, Zerante S; SONG-Tx Life Participation Workshop Investigators; Health professionals (*includes 2 patients from the SONG-Tx Graft Health Expert Working Group); Patients and family members.

Transplantation. 2019 Jun;103(6):1199-1205. doi: 10.1097/TP.0000000000002476.

PMID:
30300284
48.

Mutation pattern analysis reveals polygenic mini-drivers associated with relapse after surgery in lung adenocarcinoma.

Bennett L, Howell M, Memon D, Smowton C, Zhou C, Miller CJ.

Sci Rep. 2018 Oct 4;8(1):14830. doi: 10.1038/s41598-018-33276-3.

49.

Research priorities for childhood chronic conditions: a workshop report.

Lopez-Vargas P, Tong A, Crowe S, Alexander SI, Caldwell PHY, Campbell DE, Couper J, Davidson A, De S, Fitzgerald DA, Haddad S, Hill S, Howell M, Jaffe A, James LJ, Ju A, Manera KE, McKenzie A, Morrow AM, Odgers HL, Pinkerton R, Ralph AF, Richmond P, Shaw PJ, Singh-Grewal D, van Zwieten A, Wake M, Craig JC; Kaleidoscope Project workshop investigators.

Arch Dis Child. 2019 Mar;104(3):237-245. doi: 10.1136/archdischild-2018-315628. Epub 2018 Oct 2.

PMID:
30279157
50.

The Impact of Age on Income-Related Health Status Inequalities from Birth to Adolescence: A Systematic Review with Cross-Country Comparisons.

van Zwieten A, Saglimbene V, Teixeira-Pinto A, Howell M, Howard K, Craig JC, Wong G.

J Pediatr. 2018 Dec;203:380-390.e14. doi: 10.1016/j.jpeds.2018.07.030. Epub 2018 Sep 25.

PMID:
30266508

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