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Items: 1 to 50 of 355

1.

Effects of early maternal care on adolescent attention bias to threat in nonhuman primates.

Morin EL, Howell BR, Meyer JS, Sanchez MM.

Dev Cogn Neurosci. 2019 Apr 30;38:100643. doi: 10.1016/j.dcn.2019.100643. [Epub ahead of print]

2.

Mental Health Treatment Among Individuals Involved in the Criminal Justice System After Implementation of the Affordable Care Act.

Howell BA, Wang EA, Winkelman TNA.

Psychiatr Serv. 2019 May 29:appips201800559. doi: 10.1176/appi.ps.201800559. [Epub ahead of print]

PMID:
31138056
3.

Effects of early life stress on cocaine self-administration in post-pubertal male and female rhesus macaques.

Wakeford AGP, Morin EL, Bramlett SN, Howell BR, McCormack KM, Meyer JS, Nader MA, Sanchez MM, Howell LL.

Psychopharmacology (Berl). 2019 May 21. doi: 10.1007/s00213-019-05254-8. [Epub ahead of print]

PMID:
31115612
4.

Disentangling the effects of early caregiving experience and heritable factors on brain white matter development in rhesus monkeys.

Howell BR, Ahn M, Shi Y, Godfrey JR, Hu X, Zhu H, Styner M, Sanchez MM.

Neuroimage. 2019 Apr 9;197:625-642. doi: 10.1016/j.neuroimage.2019.04.013. [Epub ahead of print]

PMID:
30978495
5.

Identification of the kinase STK25 as an upstream activator of LATS signaling.

Lim S, Hermance N, Mudianto T, Mustaly HM, Mauricio IPM, Vittoria MA, Quinton RJ, Howell BW, Cornils H, Manning AL, Ganem NJ.

Nat Commun. 2019 Apr 4;10(1):1547. doi: 10.1038/s41467-019-09597-w.

6.

Early-Life Nutrition and Cognitive Development: Imaging Approaches.

Lin W, Baluyot KR, Yao M, Yan J, Wang L, Li G, Howell B, Elison JT, Shen D.

Nestle Nutr Inst Workshop Ser. 2019;90:121-135. doi: 10.1159/000490300. Epub 2019 Mar 13.

PMID:
30865981
7.

Early weight loss in adolescents following bariatric surgery predicts weight loss at 12 and 24 months.

Chu L, Howell B, Steinberg A, Bar-Dayan A, Toulany A, Langer JC, Hamilton JK.

Pediatr Obes. 2019 Mar 6:e12519. doi: 10.1111/ijpo.12519. [Epub ahead of print]

PMID:
30843377
8.

Health Insurance Gains After Implementation of the Affordable Care Act Among Individuals Recently on Probation: USA, 2008-2016.

Knapp CD, Howell BA, Wang EA, Shlafer RJ, Hardeman RR, Winkelman TNA.

J Gen Intern Med. 2019 Feb 27. doi: 10.1007/s11606-019-04900-3. [Epub ahead of print] No abstract available.

PMID:
30815787
9.

A Driving-Force Predictor for Estimating Pathway Activation in Patient-Specific Models of Deep Brain Stimulation.

Howell B, Gunalan K, McIntyre CC.

Neuromodulation. 2019 Feb 18. doi: 10.1111/ner.12929. [Epub ahead of print]

PMID:
30775834
10.

Analyzing the Mechanisms Behind Macrolide Antibiotic-Induced Liver Injury Using Quantitative Systems Toxicology Modeling.

Woodhead JL, Yang K, Oldach D, MacLauchlin C, Fernandes P, Watkins PB, Siler SQ, Howell BA.

Pharm Res. 2019 Feb 7;36(3):48. doi: 10.1007/s11095-019-2582-y.

11.

Antigen Production After Latency Reversal and Expression of Inhibitory Receptors in CD8+ T Cells Limit the Killing of HIV-1 Reactivated Cells.

Ruiz A, Blanch-Lombarte O, Jimenez-Moyano E, Ouchi D, Mothe B, Peña R, Galvez C, Genescà M, Martinez-Picado J, Goulder P, Barnard R, Howell B, Clotet B, Prado JG.

Front Immunol. 2019 Jan 22;9:3162. doi: 10.3389/fimmu.2018.03162. eCollection 2018.

12.

Ethanol Exposure Transiently Elevates but Persistently Inhibits Tyrosine Kinase Activity and Impairs the Growth of the Nascent Apical Dendrite.

Wang D, Enck J, Howell BW, Olson EC.

Mol Neurobiol. 2019 Jan 23. doi: 10.1007/s12035-019-1473-x. [Epub ahead of print]

PMID:
30674037
13.

Synaptic structural protein dysfunction leads to altered excitation inhibition ratios in models of autism spectrum disorder.

Howell BW, Smith KM.

Pharmacol Res. 2019 Jan;139:207-214. doi: 10.1016/j.phrs.2018.11.019. Epub 2018 Nov 19. Review.

PMID:
30465851
14.

BCL6 Inhibitor-Mediated Downregulation of Phosphorylated SAMHD1 and T Cell Activation Are Associated with Decreased HIV Infection and Reactivation.

Cai Y, Abdel-Mohsen M, Tomescu C, Xue F, Wu G, Howell BJ, Ai Y, Sun J, Azzoni L, Le Coz C, Romberg N, Montaner LJ.

J Virol. 2019 Jan 4;93(2). pii: e01073-18. doi: 10.1128/JVI.01073-18. Print 2019 Jan 15.

PMID:
30355686
15.

Quantifying the axonal pathways directly stimulated in therapeutic subcallosal cingulate deep brain stimulation.

Howell B, Choi KS, Gunalan K, Rajendra J, Mayberg HS, McIntyre CC.

Hum Brain Mapp. 2019 Feb 15;40(3):889-903. doi: 10.1002/hbm.24419. Epub 2018 Oct 11.

PMID:
30311317
16.

Quantitative Systems Toxicology Analysis of In Vitro Mechanistic Assays Reveals Importance of Bile Acid Accumulation and Mitochondrial Dysfunction in TAK-875-Induced Liver Injury.

Longo DM, Woodhead JL, Walker P, Herédi-Szabó K, Mogyorósi K, Wolenski FS, Dragan YP, Mosedale M, Siler SQ, Watkins PB, Howell BA.

Toxicol Sci. 2019 Feb 1;167(2):458-467. doi: 10.1093/toxsci/kfy253.

17.

Early Developmental Trajectories of Functional Connectivity Along the Visual Pathways in Rhesus Monkeys.

Kovacs-Balint Z, Feczko E, Pincus M, Earl E, Miranda-Dominguez O, Howell B, Morin E, Maltbie E, Li L, Steele J, Styner M, Bachevalier J, Fair D, Sanchez M.

Cereb Cortex. 2018 Oct 1. doi: 10.1093/cercor/bhy222. [Epub ahead of print]

PMID:
30272135
18.

Human Alzheimer's disease gene expression signatures and immune profile in APP mouse models: a discrete transcriptomic view of Aβ plaque pathology.

Rothman SM, Tanis KQ, Gandhi P, Malkov V, Marcus J, Pearson M, Stevens R, Gilliland J, Ware C, Mahadomrongkul V, O'Loughlin E, Zeballos G, Smith R, Howell BJ, Klappenbach J, Kennedy M, Mirescu C.

J Neuroinflammation. 2018 Sep 6;15(1):256. doi: 10.1186/s12974-018-1265-7.

19.

Joint representation of connectome-scale structural and functional profiles for identification of consistent cortical landmarks in macaque brain.

Zhang S, Jiang X, Zhang W, Zhang T, Chen H, Zhao Y, Lv J, Guo L, Howell BR, Sanchez MM, Hu X, Liu T.

Brain Imaging Behav. 2018 Sep 4. doi: 10.1007/s11682-018-9944-7. [Epub ahead of print]

PMID:
30178424
20.

Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway.

Dairaghi L, Flannery E, Giacobini P, Saglam A, Saadi H, Constantin S, Casoni F, Howell BW, Wray S.

Front Cell Neurosci. 2018 Aug 3;12:228. doi: 10.3389/fncel.2018.00228. eCollection 2018.

21.

Test-retest reliability of a stimulation-locked evoked response to deep brain stimulation in subcallosal cingulate for treatment resistant depression.

Waters AC, Veerakumar A, Choi KS, Howell B, Tiruvadi V, Bijanki KR, Crowell A, Riva-Posse P, Mayberg HS.

Hum Brain Mapp. 2018 Dec;39(12):4844-4856. doi: 10.1002/hbm.24327. Epub 2018 Aug 18.

PMID:
30120851
22.

Associations and Heritability of Auditory Encoding, Gray Matter, and Attention in Schizophrenia.

Chen YH, Howell B, Edgar JC, Huang M, Kochunov P, Hunter MA, Wootton C, Lu BY, Bustillo J, Sadek JR, Miller GA, Cañive JM.

Schizophr Bull. 2018 Aug 7. doi: 10.1093/schbul/sby111. [Epub ahead of print]

PMID:
30099543
23.

Using Quantitative Systems Toxicology to Investigate Observed Species Differences in CKA-Mediated Hepatotoxicity.

Battista C, Yang K, Stahl SH, Mettetal JT, Watkins PB, Siler SQ, Howell BA.

Toxicol Sci. 2018 Nov 1;166(1):123-130. doi: 10.1093/toxsci/kfy191.

24.

STK25 Regulates Cardiovascular Disease Progression in a Mouse Model of Hypercholesterolemia.

Cansby E, Magnusson E, Nuñez-Durán E, Amrutkar M, Pedrelli M, Parini P, Hoffmann J, Ståhlman M, Howell BW, Marschall HU, Borén J, Mahlapuu M.

Arterioscler Thromb Vasc Biol. 2018 Aug;38(8):1723-1737. doi: 10.1161/ATVBAHA.118.311241.

PMID:
29930001
25.

Prediction of Safety Margin and Optimization of Dosing Protocol for a Novel Antibiotic using Quantitative Systems Pharmacology Modeling.

Woodhead JL, Paech F, Maurer M, Engelhardt M, Schmitt-Hoffmann AH, Spickermann J, Messner S, Wind M, Witschi AT, Krähenbühl S, Siler SQ, Watkins PB, Howell BA.

Clin Transl Sci. 2018 Sep;11(5):498-505. doi: 10.1111/cts.12560. Epub 2018 Jun 7.

26.

Ultrasensitive Immunoassay for Simian Immunodeficiency Virus p27CA.

Swanstrom AE, Gorelick RJ, Wu G, Howell B, Vijayagopalan A, Shoemaker R, Oswald K, Datta SA, Keele BF, Del Prete GQ, Chertova E, Bess JW Jr, Lifson JD.

AIDS Res Hum Retroviruses. 2018 Nov;34(11):993-1001. doi: 10.1089/AID.2018.0075. Epub 2018 Jul 10.

PMID:
29869527
27.

STK25 regulates oxidative capacity and metabolic efficiency in adipose tissue.

Sütt S, Cansby E, Paul A, Amrutkar M, Nuñez-Durán E, Kulkarni NM, Ståhlman M, Borén J, Laurencikiene J, Howell BW, Enerbäck S, Mahlapuu M.

J Endocrinol. 2018 Sep;238(3):187-202. doi: 10.1530/JOE-18-0182. Epub 2018 May 24.

PMID:
29794231
28.

Action potential initiation, propagation, and cortical invasion in the hyperdirect pathway during subthalamic deep brain stimulation.

Anderson RW, Farokhniaee A, Gunalan K, Howell B, McIntyre CC.

Brain Stimul. 2018 Sep - Oct;11(5):1140-1150. doi: 10.1016/j.brs.2018.05.008. Epub 2018 May 12.

PMID:
29779963
29.

CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells.

Abdel-Mohsen M, Kuri-Cervantes L, Grau-Exposito J, Spivak AM, Nell RA, Tomescu C, Vadrevu SK, Giron LB, Serra-Peinado C, Genescà M, Castellví J, Wu G, Del Rio Estrada PM, González-Navarro M, Lynn K, King CT, Vemula S, Cox K, Wan Y, Li Q, Mounzer K, Kostman J, Frank I, Paiardini M, Hazuda D, Reyes-Terán G, Richman D, Howell B, Tebas P, Martinez-Picado J, Planelles V, Buzon MJ, Betts MR, Montaner LJ.

Sci Transl Med. 2018 Apr 18;10(437). pii: eaar6759. doi: 10.1126/scitranslmed.aar6759.

30.

The UNC/UMN Baby Connectome Project (BCP): An overview of the study design and protocol development.

Howell BR, Styner MA, Gao W, Yap PT, Wang L, Baluyot K, Yacoub E, Chen G, Potts T, Salzwedel A, Li G, Gilmore JH, Piven J, Smith JK, Shen D, Ugurbil K, Zhu H, Lin W, Elison JT.

Neuroimage. 2019 Jan 15;185:891-905. doi: 10.1016/j.neuroimage.2018.03.049. Epub 2018 Mar 22. Review.

PMID:
29578031
31.

Characterization of the stimulus waveforms generated by implantable pulse generators for deep brain stimulation.

Lempka SF, Howell B, Gunalan K, Machado AG, McIntyre CC.

Clin Neurophysiol. 2018 Apr;129(4):731-742. doi: 10.1016/j.clinph.2018.01.015. Epub 2018 Jan 31.

32.

Quantifying axonal responses in patient-specific models of subthalamic deep brain stimulation.

Gunalan K, Howell B, McIntyre CC.

Neuroimage. 2018 May 15;172:263-277. doi: 10.1016/j.neuroimage.2018.01.015. Epub 2018 Jan 10.

33.

Protein O-Mannosyltransferases Affect Sensory Axon Wiring and Dynamic Chirality of Body Posture in the Drosophila Embryo.

Baker R, Nakamura N, Chandel I, Howell B, Lyalin D, Panin VM.

J Neurosci. 2018 Feb 14;38(7):1850-1865. doi: 10.1523/JNEUROSCI.0346-17.2017. Epub 2017 Nov 22.

34.

Shaping long-term primate development: Telomere length trajectory as an indicator of early maternal maltreatment and predictor of future physiologic regulation.

Drury SS, Howell BR, Jones C, Esteves K, Morin E, Schlesinger R, Meyer JS, Baker K, Sanchez MM.

Dev Psychopathol. 2017 Dec;29(5):1539-1551. doi: 10.1017/S0954579417001225.

35.

Connectome-scale functional intrinsic connectivity networks in macaques.

Zhang W, Jiang X, Zhang S, Howell BR, Zhao Y, Zhang T, Guo L, Sanchez MM, Hu X, Liu T.

Neuroscience. 2017 Nov 19;364:1-14. doi: 10.1016/j.neuroscience.2017.08.022. Epub 2017 Aug 24.

36.

Stimulation Efficiency With Decaying Exponential Waveforms in a Wirelessly Powered Switched-Capacitor Discharge Stimulation System.

Lee HM, Howell B, Grill WM, Ghovanloo M.

IEEE Trans Biomed Eng. 2018 May;65(5):1095-1106. doi: 10.1109/TBME.2017.2741107. Epub 2017 Aug 17.

37.

HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal.

Wu G, Swanson M, Talla A, Graham D, Strizki J, Gorman D, Barnard RJ, Blair W, Søgaard OS, Tolstrup M, Østergaard L, Rasmussen TA, Sekaly RP, Archin NM, Margolis DM, Hazuda DJ, Howell BJ.

JCI Insight. 2017 Aug 17;2(16). pii: 92901. doi: 10.1172/jci.insight.92901. eCollection 2017 Aug 17.

38.

Mathematical Modeling: A Tool for Optimization of Lipid Nanoparticle-Mediated Delivery of siRNA.

Mihaila R, Ruhela D, Keough E, Cherkaev E, Chang S, Galinski B, Bartz R, Brown D, Howell B, Cunningham JJ.

Mol Ther Nucleic Acids. 2017 Jun 16;7:246-255. doi: 10.1016/j.omtn.2017.04.003. Epub 2017 Apr 12.

39.

Mechanistic Modelling of Drug-Induced Liver Injury: Investigating the Role of Innate Immune Responses.

Shoda LK, Battista C, Siler SQ, Pisetsky DS, Watkins PB, Howell BA.

Gene Regul Syst Bio. 2017 May 30;11:1177625017696074. doi: 10.1177/1177625017696074. eCollection 2017.

40.

Mechanisms of hepatotoxicity associated with the monocyclic β-lactam antibiotic BAL30072.

Paech F, Messner S, Spickermann J, Wind M, Schmitt-Hoffmann AH, Witschi AT, Howell BA, Church RJ, Woodhead J, Engelhardt M, Krähenbühl S, Maurer M.

Arch Toxicol. 2017 Nov;91(11):3647-3662. doi: 10.1007/s00204-017-1994-x. Epub 2017 May 23.

PMID:
28536862
41.

Encouraging Medicare Advantage Enrollees to Switch to Higher Quality Plans: Assessing the Effectiveness of a "Nudge" Letter.

Howell BL, Deb P, Ma S, Reid RO, Levy J, Riley GF, Conway PH, Shrank WH.

MDM Policy Pract. 2017 May 5;2(1):2381468317707206. doi: 10.1177/2381468317707206. eCollection 2017 Jan-Jun.

42.

Creating and parameterizing patient-specific deep brain stimulation pathway-activation models using the hyperdirect pathway as an example.

Gunalan K, Chaturvedi A, Howell B, Duchin Y, Lempka SF, Patriat R, Sapiro G, Harel N, McIntyre CC.

PLoS One. 2017 Apr 25;12(4):e0176132. doi: 10.1371/journal.pone.0176132. eCollection 2017.

43.

Refining Liver Safety Risk Assessment: Application of Mechanistic Modeling and Serum Biomarkers to Cimaglermin Alfa (GGF2) Clinical Trials.

Longo DM, Generaux GT, Howell BA, Siler SQ, Antoine DJ, Button D, Caggiano A, Eisen A, Iaci J, Stanulis R, Parry T, Mosedale M, Watkins PB.

Clin Pharmacol Ther. 2017 Dec;102(6):961-969. doi: 10.1002/cpt.711. Epub 2017 May 27.

44.

The de novo autism spectrum disorder RELN R2290C mutation reduces Reelin secretion and increases protein disulfide isomerase expression.

Lammert DB, Middleton FA, Pan J, Olson EC, Howell BW.

J Neurochem. 2017 Jul;142(1):89-102. doi: 10.1111/jnc.14045. Epub 2017 May 18.

45.

Impact of CVS Pharmacy's Discontinuance of Tobacco Sales on Cigarette Purchasing (2012-2014).

Polinski JM, Howell B, Gagnon MA, Kymes SM, Brennan TA, Shrank WH.

Am J Public Health. 2017 Apr;107(4):556-562. doi: 10.2105/AJPH.2016.303612. Epub 2017 Feb 16.

46.

The role of quantitative systems pharmacology modeling in the prediction and explanation of idiosyncratic drug-induced liver injury.

Woodhead JL, Watkins PB, Howell BA, Siler SQ, Shoda LKM.

Drug Metab Pharmacokinet. 2017 Feb;32(1):40-45. doi: 10.1016/j.dmpk.2016.11.008. Epub 2016 Nov 21. Review.

47.

UNC-Emory Infant Atlases for Macaque Brain Image Analysis: Postnatal Brain Development through 12 Months.

Shi Y, Budin F, Yapuncich E, Rumple A, Young JT, Payne C, Zhang X, Hu X, Godfrey J, Howell B, Sanchez MM, Styner MA.

Front Neurosci. 2017 Jan 10;10:617. doi: 10.3389/fnins.2016.00617. eCollection 2016.

48.

Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters.

Yang K, Battista C, Woodhead JL, Stahl SH, Mettetal JT, Watkins PB, Siler SQ, Howell BA.

Clin Pharmacol Ther. 2017 Apr;101(4):501-509. doi: 10.1002/cpt.619. Epub 2017 Feb 17.

49.

Dysfunction of central control of breathing in amyotrophic lateral sclerosis.

Howell BN, Newman DS.

Muscle Nerve. 2017 Aug;56(2):197-201. doi: 10.1002/mus.25564. Epub 2017 Mar 24. Review.

PMID:
28063152
50.

A Public-Private Partnership for Proactive Pharmacy-Based Outreach and Acquisition of Needed Medication in Advance of Severe Winter Weather.

Lurie N, Bunton A, Grande K, Margolis G, Howell B, Shrank WH.

JAMA Intern Med. 2017 Feb 1;177(2):271-272. doi: 10.1001/jamainternmed.2016.7208. No abstract available.

PMID:
27918834

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