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Items: 1 to 50 of 83

1.

Antiplatelet therapy in the primary prevention of cardiovascular disease in patients with chronic obstructive pulmonary disease: a randomised controlled proof-of-concept trial.

Kunadian V, Wilson N, Stocken DD, Ali H, McColl E, Burns G, Howe N, Fisher A, De Soyza A.

ERJ Open Res. 2019 Aug 5;5(3). pii: 00110-2019. doi: 10.1183/23120541.00110-2019. eCollection 2019 Jul.

2.

Brief alcohol intervention for risky drinking in young people aged 14–15 years in secondary schools: the SIPS JR-HIGH RCT.

Giles EL, McGeechan GJ, Coulton S, Deluca P, Drummond C, Howel D, Kaner E, McColl E, McGovern R, Scott S, Stamp E, Sumnall H, Todd L, Vale L, Albani V, Boniface S, Ferguson J, Gilvarry E, Hendrie N, Howe N, Mossop H, Ramsay A, Stanley G, Newbury-Birch D.

Southampton (UK): NIHR Journals Library; 2019 May.

3.

Crescentic Modification to Island Pedicle Rotation Flaps for Defects of the Distal Nose.

Howe NM, Chen DL, Holmes TE.

Dermatol Surg. 2019 Feb 18. doi: 10.1097/DSS.0000000000001855. [Epub ahead of print]

PMID:
30883480
4.

Appropriate use of Mohs surgery in immunocompromised patients is high and published indications for Mohs decrease inappropriate use.

Shin TM, O'Malley V, Tuttle S, Howe N, Etzkorn JR, Sobanko JF, Margolis DJ, Miller CJ.

J Am Acad Dermatol. 2019 Jan 8. pii: S0190-9622(19)30056-8. doi: 10.1016/j.jaad.2018.12.050. [Epub ahead of print] No abstract available.

PMID:
30633942
5.

'H, I, J, K, L, M, N, O, PEE! Get it? Pee!': Siblings' shared humour in childhood.

Paine AL, Howe N, Karajian G, Hay DF, DeHart G.

Br J Dev Psychol. 2019 Jan 9. doi: 10.1111/bjdp.12277. [Epub ahead of print]

PMID:
30623983
6.

Melanomas of the head and neck have high local recurrence risk features and require tissue rearranging reconstruction more commonly than BCC and SCC: A comparison of indications for microscopic margin control prior to reconstruction in 13,664 tumors.

Fix W, Etzkorn JR, Shin TM, Howe N, Bhatt M, Sobanko JF, Miller CJ.

J Am Acad Dermatol. 2018 Nov 17. pii: S0190-9622(18)32910-4. doi: 10.1016/j.jaad.2018.11.020. [Epub ahead of print]

PMID:
30458206
7.

The "Rule of 10s" versus the "Rule of 2s": High complication rates after conventional excision with postoperative margin assessment of specialty site versus trunk and proximal extremity melanomas.

Rzepecki AK, Hwang CD, Etzkorn JR, Shin TM, Sobanko JF, Howe NM, Miller CJ.

J Am Acad Dermatol. 2018 Nov 14. pii: S0190-9622(18)32892-5. doi: 10.1016/j.jaad.2018.11.008. [Epub ahead of print] Review.

PMID:
30447316
8.

In situ serial crystallography for rapid de novo membrane protein structure determination.

Huang CY, Olieric V, Howe N, Warshamanage R, Weinert T, Panepucci E, Vogeley L, Basu S, Diederichs K, Caffrey M, Wang M.

Commun Biol. 2018 Aug 27;1:124. doi: 10.1038/s42003-018-0123-6. eCollection 2018.

9.

Membrane (and Soluble) Protein Stability and Binding Measurements in the Lipid Cubic Phase Using Label-Free Differential Scanning Fluorimetry.

Boland C, Olatunji S, Bailey J, Howe N, Weichert D, Fetics SK, Yu X, Merino-Gracia J, Delsaut C, Caffrey M.

Anal Chem. 2018 Oct 16;90(20):12152-12160. doi: 10.1021/acs.analchem.8b03176. Epub 2018 Oct 4.

PMID:
30180556
10.

Use of a vibrating kinetic anesthesia device reduces the pain of lidocaine injections: A randomized split-body trial.

Fix WC, Chiesa-Fuxench ZC, Shin T, Etzkorn J, Howe N, Miller CJ, Sobanko JF.

J Am Acad Dermatol. 2019 Jan;80(1):58-59. doi: 10.1016/j.jaad.2018.08.011. Epub 2018 Aug 18. No abstract available.

PMID:
30130597
11.

Preoperative Behavioural Intervention versus standard care to Reduce Drinking before elective orthopaedic Surgery (PRE-OP BIRDS): protocol for a multicentre pilot randomised controlled trial.

Snowden C, Lynch E, Avery L, Gerrand C, Gilvarry E, Goudie N, Haighton C, Hall L, Howe N, Howel D, McColl E, Prentis J, Stamp E, Kaner E.

Pilot Feasibility Stud. 2018 Aug 16;4:140. doi: 10.1186/s40814-018-0330-4. eCollection 2018.

12.

Differentiating typical from atypical perpetration of sibling-directed aggression during the preschool years.

Dirks MA, Recchia HE, Estabrook R, Howe N, Petitclerc A, Burns JL, Briggs-Gowan MJ, Wakschlag LS.

J Child Psychol Psychiatry. 2019 Mar;60(3):267-276. doi: 10.1111/jcpp.12939. Epub 2018 Jul 2.

PMID:
29963711
13.

Antiplatelet therapy in the primary prevention of cardiovascular disease in patients with chronic obstructive pulmonary disease: protocol of a randomised controlled proof-of-concept trial (APPLE COPD-ICON 2).

Kunadian V, Chan D, Ali H, Wilkinson N, Howe N, McColl E, Thornton J, von Wilamowitz-Moellendorff A, Holstein EM, Burns G, Fisher A, Stocken D, De Soyza A; APPLE COPD-ICON2 Trial Investigators.

BMJ Open. 2018 May 26;8(5):e020713. doi: 10.1136/bmjopen-2017-020713.

14.

Systematic review of participants' attitudes towards data sharing: a thematic synthesis.

Howe N, Giles E, Newbury-Birch D, McColl E.

J Health Serv Res Policy. 2018 Apr;23(2):123-133. doi: 10.1177/1355819617751555.

PMID:
29653503
15.

Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis.

El Ghachi M, Howe N, Huang CY, Olieric V, Warshamanage R, Touzé T, Weichert D, Stansfeld PJ, Wang M, Kerff F, Caffrey M.

Nat Commun. 2018 Mar 14;9(1):1078. doi: 10.1038/s41467-018-03477-5.

16.

PREDICTING NORMATIVE AND PROBLEMATIC FAMILY PATHWAYS TO THE TRANSITION TO SIBLINGHOOD: COMMENTARY ON VOLLING ET AL.'S MONOGRAPH.

Howe N.

Monogr Soc Res Child Dev. 2017 Sep;82(3):184-195. doi: 10.1111/mono.12319.

PMID:
28766782
17.

Structural insights into the mechanism of the membrane integral N-acyltransferase step in bacterial lipoprotein synthesis.

Wiktor M, Weichert D, Howe N, Huang CY, Olieric V, Boland C, Bailey J, Vogeley L, Stansfeld PJ, Buddelmeijer N, Wang M, Caffrey M.

Nat Commun. 2017 Jul 4;8:15952. doi: 10.1038/ncomms15952.

18.

Siblings' Power and Influence in Polyadic Family Conflict During Early Childhood.

Della Porta S, Howe N.

New Dir Child Adolesc Dev. 2017 Jun;2017(156):15-31. doi: 10.1002/cad.20200.

PMID:
28581193
19.

Crystal structure and biochemical characterization of the transmembrane PAP2 type phosphatidylglycerol phosphate phosphatase from Bacillus subtilis.

Ghachi ME, Howe N, Auger R, Lambion A, Guiseppi A, Delbrassine F, Manat G, Roure S, Peslier S, Sauvage E, Vogeley L, Rengifo-Gonzalez JC, Charlier P, Mengin-Lecreulx D, Foglino M, Touzé T, Caffrey M, Kerff F.

Cell Mol Life Sci. 2017 Jun;74(12):2319-2332. doi: 10.1007/s00018-017-2464-6. Epub 2017 Feb 6.

PMID:
28168443
20.

Multicentre individual randomised controlled trial of screening and brief alcohol intervention to prevent risky drinking in young people aged 14-15 in a high school setting (SIPS JR-HIGH): study protocol.

Giles EL, Coulton S, Deluca P, Drummond C, Howel D, Kaner E, McColl E, McGovern R, Scott S, Stamp E, Sumnall H, Tate L, Todd L, Vale L, Albani V, Boniface S, Ferguson J, Frankham J, Gilvarry E, Hendrie N, Howe N, McGeechan GJ, Stanley G, Newbury-Birch D.

BMJ Open. 2016 Dec 23;6(12):e012474. doi: 10.1136/bmjopen-2016-012474.

21.

Optimization of Highly Kinase Selective Bis-anilino Pyrimidine PAK1 Inhibitors.

McCoull W, Hennessy EJ, Blades K, Chuaqui C, Dowling JE, Ferguson AD, Goldberg FW, Howe N, Jones CR, Kemmitt PD, Lamont G, Varnes JG, Ward RA, Yang B.

ACS Med Chem Lett. 2016 Sep 14;7(12):1118-1123. eCollection 2016 Dec 8.

22.

"Because if you don't put the top on, it will spill": A longitudinal study of sibling teaching in early childhood.

Howe N, Della Porta S, Recchia H, Ross H.

Dev Psychol. 2016 Nov;52(11):1832-1842. Epub 2016 Oct 6.

PMID:
27710000
24.

In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures.

Huang CY, Olieric V, Ma P, Howe N, Vogeley L, Liu X, Warshamanage R, Weinert T, Panepucci E, Kobilka B, Diederichs K, Wang M, Caffrey M.

Acta Crystallogr D Struct Biol. 2016 Jan;72(Pt 1):93-112. doi: 10.1107/S2059798315021683. Epub 2016 Jan 1.

25.

Ternary structure reveals mechanism of a membrane diacylglycerol kinase.

Li D, Stansfeld PJ, Sansom MSP, Keogh A, Vogeley L, Howe N, Lyons JA, Aragao D, Fromme P, Fromme R, Basu S, Grotjohann I, Kupitz C, Rendek K, Weierstall U, Zatsepin NA, Cherezov V, Liu W, Bandaru S, English NJ, Gati C, Barty A, Yefanov O, Chapman HN, Diederichs K, Messerschmidt M, Boutet S, Williams GJ, Marvin Seibert M, Caffrey M.

Nat Commun. 2015 Dec 17;6:10140. doi: 10.1038/ncomms10140.

26.

Sibling relationships as sources of risk and resilience in the development and maintenance of internalizing and externalizing problems during childhood and adolescence.

Dirks MA, Persram R, Recchia HE, Howe N.

Clin Psychol Rev. 2015 Dec;42:145-55. doi: 10.1016/j.cpr.2015.07.003. Epub 2015 Jul 29. Review.

PMID:
26254557
27.

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.

Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, Chapman HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE.

Nature. 2015 Jul 30;523(7562):561-7. doi: 10.1038/nature14656. Epub 2015 Jul 22.

28.

Fast native-SAD phasing for routine macromolecular structure determination.

Weinert T, Olieric V, Waltersperger S, Panepucci E, Chen L, Zhang H, Zhou D, Rose J, Ebihara A, Kuramitsu S, Li D, Howe N, Schnapp G, Pautsch A, Bargsten K, Prota AE, Surana P, Kottur J, Nair DT, Basilico F, Cecatiello V, Pasqualato S, Boland A, Weichenrieder O, Wang BC, Steinmetz MO, Caffrey M, Wang M.

Nat Methods. 2015 Feb;12(2):131-3. doi: 10.1038/nmeth.3211. Epub 2014 Dec 15. Erratum in: Nat Methods. 2015 Jul;12(7):692.

PMID:
25506719
29.

Skin substitutes: an overview of the key players in wound management.

Nathoo R, Howe N, Cohen G.

J Clin Aesthet Dermatol. 2014 Oct;7(10):44-8. Review.

30.

The lipid cubic phase or in meso method for crystallizing proteins. Bushings for better manual dispensing.

Caffrey M, Eifert R, Li D, Howe N.

J Appl Crystallogr. 2014 Aug 16;47(Pt 5):1804-1806. eCollection 2014 Oct 1.

31.
32.

'Hit and run' serial femtosecond crystallography of a membrane kinase in the lipid cubic phase.

Caffrey M, Li D, Howe N, Shah ST.

Philos Trans R Soc Lond B Biol Sci. 2014 Jul 17;369(1647):20130621. doi: 10.1098/rstb.2013.0621.

33.

Crystallizing Membrane Proteins in the Lipidic Mesophase. Experience with Human Prostaglandin E2 Synthase 1 and an Evolving Strategy.

Li D, Howe N, Dukkipati A, Shah ST, Bax BD, Edge C, Bridges A, Hardwicke P, Singh OM, Giblin G, Pautsch A, Pfau R, Schnapp G, Wang M, Olieric V, Caffrey M.

Cryst Growth Des. 2014 Apr 2;14(4):2034-2047. Epub 2014 Mar 7.

34.

Adenoid cystic carcinoma of the base of the tongue metastasizing to the scalp.

Saco M, Howe N, Jukic DM, Muro-Cacho C.

Dermatol Online J. 2014 Mar 17;20(3). pii: doj_21728. Review.

35.

Topical antibiotic prophylaxis for prevention of surgical wound infections from dermatologic procedures: a systematic review and meta-analysis.

Saco M, Howe N, Nathoo R, Cherpelis B.

J Dermatolog Treat. 2015 Apr;26(2):151-8. doi: 10.3109/09546634.2014.906547. Epub 2014 Apr 8. Review.

PMID:
24646178
36.

Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography.

Weierstall U, James D, Wang C, White TA, Wang D, Liu W, Spence JC, Bruce Doak R, Nelson G, Fromme P, Fromme R, Grotjohann I, Kupitz C, Zatsepin NA, Liu H, Basu S, Wacker D, Han GW, Katritch V, Boutet S, Messerschmidt M, Williams GJ, Koglin JE, Marvin Seibert M, Klinker M, Gati C, Shoeman RL, Barty A, Chapman HN, Kirian RA, Beyerlein KR, Stevens RC, Li D, Shah ST, Howe N, Caffrey M, Cherezov V.

Nat Commun. 2014;5:3309. doi: 10.1038/ncomms4309.

37.

Obtaining rapid and effective hemostasis: Part II. Electrosurgery in patients with implantable cardiac devices.

Howe N, Cherpelis B.

J Am Acad Dermatol. 2013 Nov;69(5):677.e1-677.e9. doi: 10.1016/j.jaad.2013.07.013.

PMID:
24124835
38.

Obtaining rapid and effective hemostasis: Part I. Update and review of topical hemostatic agents.

Howe N, Cherpelis B.

J Am Acad Dermatol. 2013 Nov;69(5):659.e1-659.e17. doi: 10.1016/j.jaad.2013.07.014.

PMID:
24124834
39.

Is postexcision, preradiation mammogram necessary in patients after breast-conserving surgery with negative margins.

Adkisson CD, McLaughlin SA, Vallow LA, Heckman MG, Diehl NN, Bagaria SP, Howe N, Gibson T, Pockaj B.

Ann Surg Oncol. 2013 Oct;20(10):3205-11. doi: 10.1245/s10434-013-3148-6. Epub 2013 Aug 22.

PMID:
23975292
40.

Elevated lipoprotein(a) levels and homozygous human platelet antigen 1b (HPA-1b) genotype are risk factors for intrauterine growth restriction (IUGR).

Gerhardt A, Howe N, Krüssel JS, Scharf RE, Zotz RB.

J Thromb Thrombolysis. 2014;37(2):107-17. doi: 10.1007/s11239-013-0902-3.

PMID:
23532363
41.

Discovery of AZD3514, a small-molecule androgen receptor downregulator for treatment of advanced prostate cancer.

Bradbury RH, Acton DG, Broadbent NL, Brooks AN, Carr GR, Hatter G, Hayter BR, Hill KJ, Howe NJ, Jones RD, Jude D, Lamont SG, Loddick SA, McFarland HL, Parveen Z, Rabow AA, Sharma-Singh G, Stratton NC, Thomason AG, Trueman D, Walker GE, Wells SL, Wilson J, Wood JM.

Bioorg Med Chem Lett. 2013 Apr 1;23(7):1945-8. doi: 10.1016/j.bmcl.2013.02.056. Epub 2013 Feb 21.

PMID:
23466225
42.

CT Scans in Young People in Great Britain: Temporal and Descriptive Patterns, 1993-2002.

Pearce MS, Salotti JA, Howe NL, McHugh K, Kim KP, Lee C, Craft AW, Berrington de Gonzaléz A, Parker L.

Radiol Res Pract. 2012;2012:594278. doi: 10.1155/2012/594278. Epub 2012 Jun 26.

43.

Importance of tetrahedral intermediate formation in the catalytic mechanism of the serine proteases chymotrypsin and subtilisin.

Petrillo T, O'Donohoe CA, Howe N, Malthouse JP.

Biochemistry. 2012 Aug 7;51(31):6164-70. Epub 2012 Jul 25.

PMID:
22757750
44.

Radiation exposure from CT scans in childhood and subsequent risk of leukaemia and brain tumours: a retrospective cohort study.

Pearce MS, Salotti JA, Little MP, McHugh K, Lee C, Kim KP, Howe NL, Ronckers CM, Rajaraman P, Sir Craft AW, Parker L, Berrington de González A.

Lancet. 2012 Aug 4;380(9840):499-505. doi: 10.1016/S0140-6736(12)60815-0. Epub 2012 Jun 7.

45.

Mechanism of the binding of Z-L-tryptophan and Z-L-phenylalanine to thermolysin and stromelysin-1 in aqueous solutions.

Ceruso M, Howe N, Malthouse JP.

Biochim Biophys Acta. 2012 Feb;1824(2):303-10. doi: 10.1016/j.bbapap.2011.10.007. Epub 2011 Oct 19.

PMID:
22037182
46.

pH stability of the stromelysin-1 catalytic domain and its mechanism of interaction with a glyoxal inhibitor.

Howe N, Ceruso M, Spink E, Malthouse JP.

Biochim Biophys Acta. 2011 Oct;1814(10):1394-403. doi: 10.1016/j.bbapap.2011.07.004. Epub 2011 Jul 18.

PMID:
21782982
47.

Candida albicans cell wall components and farnesol stimulate the expression of both inflammatory and regulatory cytokines in the murine RAW264.7 macrophage cell line.

Ghosh S, Howe N, Volk K, Tati S, Nickerson KW, Petro TM.

FEMS Immunol Med Microbiol. 2010 Oct;60(1):63-73. doi: 10.1111/j.1574-695X.2010.00717.x.

48.

Children's understanding and production of verbal irony in family conversations.

Recchia HE, Howe N, Ross HS, Alexander S.

Br J Dev Psychol. 2010 Jun;28(Pt 2):255-74.

PMID:
20481387
49.

Associations between social understanding, sibling relationship quality, and siblings' conflict strategies and outcomes.

Recchia HE, Howe N.

Child Dev. 2009 Sep-Oct;80(5):1564-78. doi: 10.1111/j.1467-8624.2009.01351.x.

PMID:
19765018
50.

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