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Items: 18


Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation.

Howden AJM, Hukelmann JL, Brenes A, Spinelli L, Sinclair LV, Lamond AI, Cantrell DA.

Nat Immunol. 2019 Oct 7. doi: 10.1038/s41590-019-0495-x. [Epub ahead of print]


Antigen receptor control of methionine metabolism in T cells.

Sinclair LV, Howden AJ, Brenes A, Spinelli L, Hukelmann JL, Macintyre AN, Liu X, Thomson S, Taylor PM, Rathmell JC, Locasale JW, Lamond AI, Cantrell DA.

Elife. 2019 Mar 27;8. pii: e44210. doi: 10.7554/eLife.44210.


The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human.

Mir R, Tonelli F, Lis P, Macartney T, Polinski NK, Martinez TN, Chou MY, Howden AJM, König T, Hotzy C, Milenkovic I, Brücke T, Zimprich A, Sammler E, Alessi DR.

Biochem J. 2018 Jun 6;475(11):1861-1883. doi: 10.1042/BCJ20180248.


Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.

Fan Y, Howden AJM, Sarhan AR, Lis P, Ito G, Martinez TN, Brockmann K, Gasser T, Alessi DR, Sammler EM.

Biochem J. 2018 Jan 2;475(1):23-44. doi: 10.1042/BCJ20170803.


Quantitative analysis of the tomato nuclear proteome during Phytophthora capsici infection unveils regulators of immunity.

Howden AJM, Stam R, Martinez Heredia V, Motion GB, Ten Have S, Hodge K, Marques Monteiro Amaro TM, Huitema E.

New Phytol. 2017 Jul;215(1):309-322. doi: 10.1111/nph.14540. Epub 2017 Apr 10.


DNA-binding protein prediction using plant specific support vector machines: validation and application of a new genome annotation tool.

Motion GB, Howden AJ, Huitema E, Jones S.

Nucleic Acids Res. 2015 Dec 15;43(22):e158. doi: 10.1093/nar/gkv805. Epub 2015 Aug 24.


Characterization of cell death inducing Phytophthora capsici CRN effectors suggests diverse activities in the host nucleus.

Stam R, Howden AJ, Delgado-Cerezo M, M M Amaro TM, Motion GB, Pham J, Huitema E.

Front Plant Sci. 2013 Oct 21;4:387. doi: 10.3389/fpls.2013.00387. eCollection 2013.


Phytophthora capsici-tomato interaction features dramatic shifts in gene expression associated with a hemi-biotrophic lifestyle.

Jupe J, Stam R, Howden AJ, Morris JA, Zhang R, Hedley PE, Huitema E.

Genome Biol. 2013 Jun 25;14(6):R63. doi: 10.1186/gb-2013-14-6-r63.


Identification and Characterisation CRN Effectors in Phytophthora capsici Shows Modularity and Functional Diversity.

Stam R, Jupe J, Howden AJ, Morris JA, Boevink PC, Hedley PE, Huitema E.

PLoS One. 2013;8(3):e59517. doi: 10.1371/journal.pone.0059517. Epub 2013 Mar 25.


QuaNCAT: quantitating proteome dynamics in primary cells.

Howden AJ, Geoghegan V, Katsch K, Efstathiou G, Bhushan B, Boutureira O, Thomas B, Trudgian DC, Kessler BM, Dieterich DC, Davis BG, Acuto O.

Nat Methods. 2013 Apr;10(4):343-6. doi: 10.1038/nmeth.2401. Epub 2013 Mar 10.


Effector-triggered post-translational modifications and their role in suppression of plant immunity.

Howden AJ, Huitema E.

Front Plant Sci. 2012 Jul 16;3:160. doi: 10.3389/fpls.2012.00160. eCollection 2012.


Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis.

Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ.

Plant Physiol. 2011 Apr;155(4):1779-90. doi: 10.1104/pp.110.171595. Epub 2011 Feb 10.


The phosphoproteome of Arabidopsis plants lacking the oxidative signal-inducible1 (OXI1) protein kinase.

Howden AJ, Salek M, Miguet L, Pullen M, Thomas B, Knight MR, Sweetlove LJ.

New Phytol. 2011 Apr;190(1):49-56. doi: 10.1111/j.1469-8137.2010.03582.x. Epub 2010 Dec 22.


A genome-scale metabolic model accurately predicts fluxes in central carbon metabolism under stress conditions.

Williams TC, Poolman MG, Howden AJ, Schwarzlander M, Fell DA, Ratcliffe RG, Sweetlove LJ.

Plant Physiol. 2010 Sep;154(1):311-23. doi: 10.1104/pp.110.158535. Epub 2010 Jul 6.


Pseudomonas syringae pv. syringae B728a hydrolyses indole-3-acetonitrile to the plant hormone indole-3-acetic acid.

Howden AJ, Rico A, Mentlak T, Miguet L, Preston GM.

Mol Plant Pathol. 2009 Nov;10(6):857-65. doi: 10.1111/j.1364-3703.2009.00595.x.


Nitrilase enzymes and their role in plant-microbe interactions.

Howden AJ, Preston GM.

Microb Biotechnol. 2009 Jul;2(4):441-51. doi: 10.1111/j.1751-7915.2009.00111.x. Epub 2009 Apr 16. Review.


A conserved mechanism for nitrile metabolism in bacteria and plants.

Howden AJ, Harrison CJ, Preston GM.

Plant J. 2009 Jan;57(2):243-53. doi: 10.1111/j.1365-313X.2008.03682.x. Epub 2008 Oct 7.


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