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Items: 34

1.

Combining High-Resolution and Exact Calibration To Boost Statistical Power: A Well-Calibrated Score Function for High-Resolution MS2 Data.

Lin A, Howbert JJ, Noble WS.

J Proteome Res. 2018 Nov 2;17(11):3644-3656. doi: 10.1021/acs.jproteome.8b00206. Epub 2018 Oct 18.

PMID:
30221945
2.

PREDICTD PaRallel Epigenomics Data Imputation with Cloud-based Tensor Decomposition.

Durham TJ, Libbrecht MW, Howbert JJ, Bilmes J, Noble WS.

Nat Commun. 2018 Apr 11;9(1):1402. doi: 10.1038/s41467-018-03635-9.

3.

Correction: Forecasting Seizures Using Bivariate Intracranial EEG Measures and SVM in Naturally Occurring Canine Epilepsy.

Brinkmann BH, Patterson EE, Vite C, Vasoli VM, Crepeau D, Stead M, Howbert JJ, Cherkassky V, Wagenaar JB, Litt B, Worrell GA.

PLoS One. 2016 May 26;11(5):e0156476. doi: 10.1371/journal.pone.0156476. eCollection 2016.

4.

Forecasting Seizures Using Intracranial EEG Measures and SVM in Naturally Occurring Canine Epilepsy.

Brinkmann BH, Patterson EE, Vite C, Vasoli VM, Crepeau D, Stead M, Howbert JJ, Cherkassky V, Wagenaar JB, Litt B, Worrell GA.

PLoS One. 2015 Aug 4;10(8):e0133900. doi: 10.1371/journal.pone.0133900. eCollection 2015. Erratum in: PLoS One. 2016;11(5):e0156476.

5.

Crux: rapid open source protein tandem mass spectrometry analysis.

McIlwain S, Tamura K, Kertesz-Farkas A, Grant CE, Diament B, Frewen B, Howbert JJ, Hoopmann MR, Käll L, Eng JK, MacCoss MJ, Noble WS.

J Proteome Res. 2014 Oct 3;13(10):4488-91. doi: 10.1021/pr500741y. Epub 2014 Sep 9.

6.

Computing exact p-values for a cross-correlation shotgun proteomics score function.

Howbert JJ, Noble WS.

Mol Cell Proteomics. 2014 Sep;13(9):2467-79. doi: 10.1074/mcp.O113.036327. Epub 2014 Jun 2.

7.

Forecasting seizures in dogs with naturally occurring epilepsy.

Howbert JJ, Patterson EE, Stead SM, Brinkmann B, Vasoli V, Crepeau D, Vite CH, Sturges B, Ruedebusch V, Mavoori J, Leyde K, Sheffield WD, Litt B, Worrell GA.

PLoS One. 2014 Jan 8;9(1):e81920. doi: 10.1371/journal.pone.0081920. eCollection 2014.

8.

VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC.

Lu H, Dietsch GN, Matthews MA, Yang Y, Ghanekar S, Inokuma M, Suni M, Maino VC, Henderson KE, Howbert JJ, Disis ML, Hershberg RM.

Clin Cancer Res. 2012 Jan 15;18(2):499-509. doi: 10.1158/1078-0432.CCR-11-1625. Epub 2011 Nov 29.

9.

MR-Tandem: parallel X!Tandem using Hadoop MapReduce on Amazon Web Services.

Pratt B, Howbert JJ, Tasman NI, Nilsson EJ.

Bioinformatics. 2012 Jan 1;28(1):136-7. doi: 10.1093/bioinformatics/btr615. Epub 2011 Nov 8.

10.

Identification of TNF-alpha inhibitors from a split-pool library based on a tyrosine-proline peptidomimetic scaffold.

Jackson RW, Tabone JC, Howbert JJ.

Bioorg Med Chem Lett. 2003 Jan 20;13(2):205-8.

PMID:
12482424
11.

Benzobicyclooctanes as novel inhibitors of TNF-alpha signaling.

Jackson RW, Gelinas R, Baughman TA, Cox T, Howbert JJ, Kucera KA, Latham JA, Ramsdell F, Singh D, Darwish IS.

Bioorg Med Chem Lett. 2002 Apr 8;12(7):1093-7.

PMID:
11909725
12.

Of monkeys and men: vervets and the genetics of human-like behaviors.

Palmour RM, Mulligan J, Howbert JJ, Ervin F.

Am J Hum Genet. 1997 Sep;61(3):481-8. No abstract available.

13.

[3H]LY303870, a novel nonpeptide radioligand for the NK-1 receptor.

Gehlert DR, Schober DA, Hipskind PA, Gitter BD, Howbert JJ.

J Neurochem. 1996 Mar;66(3):1095-102.

PMID:
8769871
14.

3-Aryl-1,2-diacetamidopropane derivatives as novel and potent NK-1 receptor antagonists.

Hipskind PA, Howbert JJ, Bruns RF, Cho SS, Crowell TA, Foreman MM, Gehlert DR, Iyengar S, Johnson KW, Krushinski JH, Li DL, Lobb KL, Mason NR, Muehl BS, Nixon JA, Phebus LA, Regoli D, Simmons RM, Threlkeld PG, Waters DC, Gitter BD.

J Med Chem. 1996 Feb 2;39(3):736-48.

PMID:
8576917
15.

Pharmacological characterization of LY303870: a novel, potent and selective nonpeptide substance P (neurokinin-1) receptor antagonist.

Gitter BD, Bruns RF, Howbert JJ, Waters DC, Threlkeld PG, Cox LM, Nixon JA, Lobb KL, Mason NR, Stengel PW, et al.

J Pharmacol Exp Ther. 1995 Nov;275(2):737-44.

PMID:
7473161
16.

Novel halogenated analogs of tomoxetine that are potent and selective inhibitors of norepinephrine uptake in brain.

Gehlert DR, Schober DA, Hemrick-Luecke SK, Krushinski J, Howbert JJ, Robertson DW, Fuller RW, Wong DT.

Neurochem Int. 1995 Jan;26(1):47-52.

PMID:
7787762
17.

(R)-thionisoxetine, a potent and selective inhibitor of central and peripheral norepinephrine uptake.

Gehlert DR, Hemrick-Luecke SK, Schober DA, Krushinski J, Howbert JJ, Robertson DW, Wong DT, Fuller RW.

Life Sci. 1995;56(22):1915-20.

PMID:
7746100
18.

Interleukin-6 secretion from human astrocytoma cells induced by substance P.

Gitter BD, Regoli D, Howbert JJ, Glasebrook AL, Waters DC.

J Neuroimmunol. 1994 Apr;51(1):101-8.

PMID:
7512575
20.

Tachykinin receptor antagonists inhibit hyperpnea-induced bronchoconstriction in guinea pigs.

Solway J, Kao BM, Jordan JE, Gitter B, Rodger IW, Howbert JJ, Alger LE, Necheles J, Leff AR, Garland A.

J Clin Invest. 1993 Jul;92(1):315-23.

21.

Use of non-peptide tachykinin receptor antagonists to substantiate the involvement of NK1 and NK2 receptors in a spinal nociceptive reflex in the rat.

Picard P, Boucher S, Regoli D, Gitter BD, Howbert JJ, Couture R.

Eur J Pharmacol. 1993 Mar 2;232(2-3):255-61.

PMID:
7682180
22.

Electrophysiological effects of diphenylpyrazolidinone cholecystokinin-B and cholecystokinin-A antagonists on midbrain dopamine neurons.

Rasmussen K, Czachura JF, Stockton ME, Howbert JJ.

J Pharmacol Exp Ther. 1993 Jan;264(1):480-8.

PMID:
8423546
23.

Comparison of metabolism and toxicity to the structure of the anticancer agent sulofenur and related sulfonylureas.

Ehlhardt WJ, Woodland JM, Worzalla JF, Bewley JR, Grindey GB, Todd GC, Toth JE, Howbert JJ.

Chem Res Toxicol. 1992 Sep-Oct;5(5):667-73.

PMID:
1446007
24.

Inhibition of PAIII rat prostatic adenocarcinoma growth and metastasis by a new diarylsulfonylurea antitumor agent, LY181984.

Neubauer BL, Merriman RL, Best KL, Goode RL, Sarosdy MF, Tanzer LR, Howbert JJ.

J Urol. 1992 Feb;147(2):500-4.

PMID:
1732631
25.

Cholecystokinin (CCK) and schizophrenia: the selective CCKB antagonist LY262691 decreases midbrain dopamine unit activity.

Rasmussen K, Stockton ME, Czachura JF, Howbert JJ.

Eur J Pharmacol. 1991 Dec 10;209(1-2):135-8.

PMID:
1687681
26.

Species differences in affinities of non-peptide antagonists for substance P receptors.

Gitter BD, Waters DC, Bruns RF, Mason NR, Nixon JA, Howbert JJ.

Eur J Pharmacol. 1991 May 17;197(2-3):237-8. No abstract available.

PMID:
1717291
27.

Selectivity and specificity of new, non-peptide, quinuclidine antagonists of substance P.

Rouissi N, Gitter BD, Waters DC, Howbert JJ, Nixon JA, Regoli D.

Biochem Biophys Res Commun. 1991 Apr 30;176(2):894-901.

PMID:
1709018
28.

Inhibition of protein kinase C by calphostin C is light-dependent.

Bruns RF, Miller FD, Merriman RL, Howbert JJ, Heath WF, Kobayashi E, Takahashi I, Tamaoki T, Nakano H.

Biochem Biophys Res Commun. 1991 Apr 15;176(1):288-93.

PMID:
1708246
29.

Metabolism and disposition of p-chloroaniline in rat, mouse, and monkey.

Ehlhardt WJ, Howbert JJ.

Drug Metab Dispos. 1991 Mar-Apr;19(2):366-9.

PMID:
1676638
30.

Novel agents effective against solid tumors: the diarylsulfonylureas. Synthesis, activities, and analysis of quantitative structure-activity relationships.

Howbert JJ, Grossman CS, Crowell TA, Rieder BJ, Harper RW, Kramer KE, Tao EV, Aikins J, Poore GA, Rinzel SM, et al.

J Med Chem. 1990 Sep;33(9):2393-407.

PMID:
2391684
31.

Studies on the cellular pharmacology of N-(4-methylphenylsulfonyl)-N'-(4-chlorophenyl)-urea.

Houghton PJ, Bailey FC, Germain GS, Grindey GB, Howbert JJ, Houghton JA.

Biochem Pharmacol. 1990 Apr 1;39(7):1187-92.

PMID:
2322303
32.

Evidence for mitochondrial localization of N-(4-methylphenylsulfonyl)-N'-(4-chlorophenyl)urea in human colon adenocarcinoma cells.

Houghton PJ, Bailey FC, Houghton JA, Murti KG, Howbert JJ, Grindey GB.

Cancer Res. 1990 Feb 1;50(3):664-8.

33.

Potent inhibition of interleukin 1 beta-mediated human melanoma (A375.6) lysis by corticosteroids, staurosporine, and tilorone.

Schultz RM, Howbert JJ, Archer RA.

Immunopharmacol Immunotoxicol. 1989;11(2-3):489-506.

PMID:
2621325
34.

Evaluation of N-(5-indanylsulfonyl)-N'-(4-chlorophenyl)-urea against xenografts of pediatric rhabdomyosarcoma.

Houghton PJ, Houghton JA, Myers L, Cheshire P, Howbert JJ, Grindey GB.

Cancer Chemother Pharmacol. 1989;25(2):84-8.

PMID:
2598403

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