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Items: 1 to 50 of 104

1.

Capsaicin inhibits the function of α7-nicotinic acetylcholine receptors expressed in Xenopus oocytes and rat hippocampal neurons.

Alzaabi AH, Howarth L, El Nebrisi E, Syed N, Susan Yang KH, Howarth FC, Oz M.

Eur J Pharmacol. 2019 Aug 15;857:172411. doi: 10.1016/j.ejphar.2019.172411. Epub 2019 May 30.

PMID:
31152699
2.

Natural Negative Allosteric Modulators of 5-HT₃ Receptors.

Al Kury LT, Mahgoub M, Howarth FC, Oz M.

Molecules. 2018 Dec 3;23(12). pii: E3186. doi: 10.3390/molecules23123186. Review.

3.

The Pattern of mRNA Expression Is Changed in Sinoatrial Node from Goto-Kakizaki Type 2 Diabetic Rat Heart.

Howarth FC, Qureshi MA, Jayaprakash P, Parekh K, Oz M, Dobrzynski H, Adrian TE.

J Diabetes Res. 2018 Sep 2;2018:8454078. doi: 10.1155/2018/8454078. eCollection 2018.

4.

Therapeutic potential of benfotiamine and its molecular targets.

Raj V, Ojha S, Howarth FC, Belur PD, Subramanya SB.

Eur Rev Med Pharmacol Sci. 2018 May;22(10):3261-3273. doi: 10.26355/eurrev_201805_15089.

5.

Calcium Signaling in the Ventricular Myocardium of the Goto-Kakizaki Type 2 Diabetic Rat.

Al Kury L, Smail M, Qureshi MA, Sydorenko V, Shmygol A, Oz M, Singh J, Howarth FC.

J Diabetes Res. 2018 Apr 10;2018:2974304. doi: 10.1155/2018/2974304. eCollection 2018. Review.

6.

Type 1 diabetes mellitus induces structural changes and molecular remodelling in the rat kidney.

Singh RM, Howarth FC, Adeghate E, Bidasee K, Singh J, Waqar T.

Mol Cell Biochem. 2018 Dec;449(1-2):9-25. doi: 10.1007/s11010-018-3338-4. Epub 2018 Feb 23.

PMID:
29476359
7.

Cell shortening and calcium dynamics in epicardial and endocardial myocytes from the left ventricle of Goto-Kakizaki type 2 diabetic rats.

Smail M, Al Kury L, Qureshi MA, Shmygol A, Oz M, Singh J, Howarth FC.

Exp Physiol. 2018 Apr 1;103(4):502-511. doi: 10.1113/EP086542. Epub 2018 Feb 25.

PMID:
29363193
8.

Curcumin potentiates the function of human α7-nicotinic acetylcholine receptors expressed in SH-EP1 cells.

Nebrisi EE, Al Kury LT, Yang KS, Jayaprakash P, Howarth FC, Kabbani N, Oz M.

Neurochem Int. 2018 Mar;114:80-84. doi: 10.1016/j.neuint.2017.12.010. Epub 2018 Jan 16.

9.

Curcumin Acts as a Positive Allosteric Modulator of α7-Nicotinic Acetylcholine Receptors and Reverses Nociception in Mouse Models of Inflammatory Pain.

El Nebrisi EG, Bagdas D, Toma W, Al Samri H, Brodzik A, Alkhlaif Y, Yang KS, Howarth FC, Damaj IM, Oz M.

J Pharmacol Exp Ther. 2018 Apr;365(1):190-200. doi: 10.1124/jpet.117.245068. Epub 2018 Jan 16.

PMID:
29339457
10.

Voltage dependence of the Ca2+ transient in endocardial and epicardial myocytes from the left ventricle of Goto-Kakizaki type 2 diabetic rats.

Al Kury L, Sydorenko V, Smail MMA, Qureshi MA, Shmygol A, Oz M, Singh J, Howarth FC.

Mol Cell Biochem. 2018 Sep;446(1-2):25-33. doi: 10.1007/s11010-018-3269-0. Epub 2018 Jan 9.

PMID:
29318456
11.

Hyperglycemia-induced cardiac contractile dysfunction in the diabetic heart.

Singh RM, Waqar T, Howarth FC, Adeghate E, Bidasee K, Singh J.

Heart Fail Rev. 2018 Jan;23(1):37-54. doi: 10.1007/s10741-017-9663-y. Review.

PMID:
29192360
12.

Effects of pioglitazone on ventricular myocyte shortening and Ca(2+) transport in the Goto-Kakizaki type 2 diabetic rat.

Salem KA, Sydorenko V, Qureshi M, Oz M, Howarth FC.

Physiol Res. 2018 Mar 16;67(1):57-68. Epub 2017 Nov 10.

13.

Cellular and Molecular Targets of Menthol Actions.

Oz M, El Nebrisi EG, Yang KS, Howarth FC, Al Kury LT.

Front Pharmacol. 2017 Jul 18;8:472. doi: 10.3389/fphar.2017.00472. eCollection 2017. Review.

14.

Altered profile of mRNA expression in atrioventricular node of streptozotocin‑induced diabetic rats.

Howarth FC, Parekh K, Jayaprakash P, Inbaraj ES, Oz M, Dobrzynski H, Adrian TE.

Mol Med Rep. 2017 Oct;16(4):3720-3730. doi: 10.3892/mmr.2017.7038. Epub 2017 Jul 20.

15.

Regional effects of streptozotocin-induced diabetes on shortening and calcium transport in epicardial and endocardial myocytes from rat left ventricle.

Smail MM, Qureshi MA, Shmygol A, Oz M, Singh J, Sydorenko V, Arabi A, Howarth FC, Al Kury L.

Physiol Rep. 2016 Nov;4(22). pii: e13034.

16.

Different Profile of mRNA Expression in Sinoatrial Node from Streptozotocin-Induced Diabetic Rat.

Ferdous Z, Qureshi MA, Jayaprakash P, Parekh K, John A, Oz M, Raza H, Dobrzynski H, Adrian TE, Howarth FC.

PLoS One. 2016 Apr 20;11(4):e0153934. doi: 10.1371/journal.pone.0153934. eCollection 2016.

17.

Exercise-induced alterations in pancreatic oxidative stress and mitochondrial function in type 2 diabetic Goto-Kakizaki rats.

Raza H, John A, Shafarin J, Howarth FC.

Physiol Rep. 2016 Apr;4(8). pii: e12751. doi: 10.14814/phy2.12751.

18.

Inhibition of human α7 nicotinic acetylcholine receptors by cyclic monoterpene carveol.

Lozon Y, Sultan A, Lansdell SJ, Prytkova T, Sadek B, Yang KH, Howarth FC, Millar NS, Oz M.

Eur J Pharmacol. 2016 Apr 5;776:44-51. doi: 10.1016/j.ejphar.2016.02.004. Epub 2016 Feb 2.

19.

Characterization of L-type calcium channel activity in atrioventricular nodal myocytes from rats with streptozotocin-induced Diabetes mellitus.

Yuill KH, Al Kury LT, Howarth FC.

Physiol Rep. 2015 Nov;3(11). pii: e12632. doi: 10.14814/phy2.12632. Epub 2015 Nov 24.

20.
21.

Inhibitory actions of bisabolol on α7-nicotinic acetylcholine receptors.

Nurulain S, Prytkova T, Sultan AM, Ievglevskyi O, Lorke D, Yang KH, Petroianu G, Howarth FC, Kabbani N, Oz M.

Neuroscience. 2015 Oct 15;306:91-9. doi: 10.1016/j.neuroscience.2015.08.019. Epub 2015 Aug 15.

PMID:
26283025
22.

Enhanced Glucose Tolerance and Pancreatic Beta Cell Function by Low Dose Aspirin in Hyperglycemic Insulin-Resistant Type 2 Diabetic Goto-Kakizaki (GK) Rats.

Amiri L, John A, Shafarin J, Adeghate E, Jayaprakash P, Yasin J, Howarth FC, Raza H.

Cell Physiol Biochem. 2015;36(5):1939-50. doi: 10.1159/000430162. Epub 2015 Jul 17.

23.

Increased oxidative stress and mitochondrial dysfunction in zucker diabetic rat liver and brain.

Raza H, John A, Howarth FC.

Cell Physiol Biochem. 2015;35(3):1241-51. doi: 10.1159/000373947. Epub 2015 Feb 11.

24.

Effects of cannabidiol on contractions and calcium signaling in rat ventricular myocytes.

Ali RM, Al Kury LT, Yang KH, Qureshi A, Rajesh M, Galadari S, Shuba YM, Howarth FC, Oz M.

Cell Calcium. 2015 Apr;57(4):290-9. doi: 10.1016/j.ceca.2015.02.001. Epub 2015 Feb 9.

25.

Effects of antihistamines on the function of human α7-nicotinic acetylcholine receptors.

Sadek B, Khanian SS, Ashoor A, Prytkova T, Ghattas MA, Atatreh N, Nurulain SM, Yang KH, Howarth FC, Oz M.

Eur J Pharmacol. 2015 Jan 5;746:308-16. doi: 10.1016/j.ejphar.2014.10.046. Epub 2014 Nov 8.

PMID:
25445036
26.

Dapagliflozin reduces the amplitude of shortening and Ca(2+) transient in ventricular myocytes from streptozotocin-induced diabetic rats.

Hamouda NN, Sydorenko V, Qureshi MA, Alkaabi JM, Oz M, Howarth FC.

Mol Cell Biochem. 2015 Feb;400(1-2):57-68. doi: 10.1007/s11010-014-2262-5. Epub 2014 Oct 29.

PMID:
25351341
27.

Effects of the endogenous cannabinoid anandamide on voltage-dependent sodium and calcium channels in rat ventricular myocytes.

Al Kury LT, Voitychuk OI, Yang KH, Thayyullathil FT, Doroshenko P, Ramez AM, Shuba YM, Galadari S, Howarth FC, Oz M.

Br J Pharmacol. 2014 Jul;171(14):3485-98. doi: 10.1111/bph.12734.

28.

Effects of a sucrose-enriched diet on the pattern of gene expression, contraction and Ca(2+) transport in Goto-Kakizaki type 2 diabetic rat heart.

Gaber EM, Jayaprakash P, Qureshi MA, Parekh K, Oz M, Adrian TE, Howarth FC.

Exp Physiol. 2014 Jun;99(6):881-93. doi: 10.1113/expphysiol.2013.077594. Epub 2014 Mar 28.

29.

Effects of endogenous cannabinoid anandamide on cardiac Na⁺/Ca²⁺ exchanger.

Al Kury LT, Yang KH, Thayyullathil FT, Rajesh M, Ali RM, Shuba YM, Howarth FC, Galadari S, Oz M.

Cell Calcium. 2014 May;55(5):231-7. doi: 10.1016/j.ceca.2014.02.017. Epub 2014 Mar 11.

PMID:
24674601
30.

Effects of endogenous cannabinoid anandamide on excitation-contraction coupling in rat ventricular myocytes.

Al Kury LT, Voitychuk OI, Ali RM, Galadari S, Yang KH, Howarth FC, Shuba YM, Oz M.

Cell Calcium. 2014 Feb;55(2):104-18. doi: 10.1016/j.ceca.2013.12.005. Epub 2014 Jan 5.

PMID:
24472666
31.

Increased metabolic stress in Zucker diabetic fatty rat kidney and pancreas.

Raza H, John A, Howarth FC.

Cell Physiol Biochem. 2013;32(6):1610-20. doi: 10.1159/000356597. Epub 2013 Dec 5.

32.

Menthol inhibits 5-HT3 receptor-mediated currents.

Ashoor A, Nordman JC, Veltri D, Yang KH, Shuba Y, Al Kury L, Sadek B, Howarth FC, Shehu A, Kabbani N, Oz M.

J Pharmacol Exp Ther. 2013 Nov;347(2):398-409. doi: 10.1124/jpet.113.203976. Epub 2013 Aug 21. Erratum in: J Pharmacol Exp Ther. 2013 Dec;347(3):816.

PMID:
23965380
33.

Menthol binding and inhibition of α7-nicotinic acetylcholine receptors.

Ashoor A, Nordman JC, Veltri D, Yang KH, Al Kury L, Shuba Y, Mahgoub M, Howarth FC, Sadek B, Shehu A, Kabbani N, Oz M.

PLoS One. 2013 Jul 23;8(7):e67674. doi: 10.1371/journal.pone.0067674. Print 2013.

34.

Effects of exercise training on excitation-contraction coupling and related mRNA expression in hearts of Goto-Kakizaki type 2 diabetic rats.

Salem KA, Qureshi MA, Sydorenko V, Parekh K, Jayaprakash P, Iqbal T, Singh J, Oz M, Adrian TE, Howarth FC.

Mol Cell Biochem. 2013 Aug;380(1-2):83-96. doi: 10.1007/s11010-013-1662-2. Epub 2013 Apr 26.

PMID:
23620341
35.

Vitamin E ameliorates the decremental effect of paraquat on cardiomyocyte contractility in rats.

Fahim MA, Howarth FC, Nemmar A, Qureshi MA, Shafiullah M, Jayaprakash P, Hasan MY.

PLoS One. 2013;8(3):e57651. doi: 10.1371/journal.pone.0057651. Epub 2013 Mar 18.

36.

Chronic effects of mild hyperglycaemia on left ventricle transcriptional profile and structural remodelling in the spontaneously type 2 diabetic Goto-Kakizaki rat.

D'Souza A, Howarth FC, Yanni J, Dobrzynski H, Boyett MR, Adeghate E, Bidasee KR, Singh J.

Heart Fail Rev. 2014 Jan;19(1):65-74. doi: 10.1007/s10741-013-9376-9.

PMID:
23430124
37.

Biocompatibility of calcined mesoporous silica particles with ventricular myocyte structure and function.

Aburawi EH, Qureshi MA, Oz D, Jayaprakash P, Tariq S, Hameed RS, Das S, Goswami A, Biradar AV, Asefa T, Souid AK, Adeghate E, Howarth FC.

Chem Res Toxicol. 2013 Jan 18;26(1):26-36. doi: 10.1021/tx300255u. Epub 2012 Dec 13.

PMID:
23237634
38.
39.

Modulation of excitability, membrane currents and survival of cardiac myocytes by N-acylethanolamines.

Voitychuk OI, Asmolkova VS, Gula NM, Sotkis GV, Galadari S, Howarth FC, Oz M, Shuba YM.

Biochim Biophys Acta. 2012 Sep;1821(9):1167-76. doi: 10.1016/j.bbalip.2012.05.003. Epub 2012 May 18.

PMID:
22613942
40.

Shortening and intracellular Ca2+ in ventricular myocytes and expression of genes encoding cardiac muscle proteins in early onset type 2 diabetic Goto-Kakizaki rats.

Salem KA, Adrian TE, Qureshi MA, Parekh K, Oz M, Howarth FC.

Exp Physiol. 2012 Dec;97(12):1281-91. doi: 10.1113/expphysiol.2012.066639. Epub 2012 May 11.

41.

Pancreatic peptides in young and elderly Zucker type 2 diabetic fatty rats.

Howarth FC, Al Kitbi MK, Hameed RS, Adeghate E.

JOP. 2011 Nov 9;12(6):567-73.

42.

Contractility of ventricular myocytes is well preserved despite altered mechanisms of Ca2+ transport and a changing pattern of mRNA in aged type 2 Zucker diabetic fatty rat heart.

Howarth FC, Qureshi MA, Hassan Z, Isaev D, Parekh K, John A, Oz M, Raza H, Adeghate E, Adrian TE.

Mol Cell Biochem. 2012 Feb;361(1-2):267-80. doi: 10.1007/s11010-011-1112-y. Epub 2011 Oct 19.

PMID:
22009485
43.

Structural lesions and changing pattern of expression of genes encoding cardiac muscle proteins are associated with ventricular myocyte dysfunction in type 2 diabetic Goto-Kakizaki rats fed a high-fat diet.

Howarth FC, Qureshi MA, Sobhy ZH, Parekh K, Yammahi SR, Adrian TE, Adeghate E.

Exp Physiol. 2011 Aug;96(8):765-77. doi: 10.1113/expphysiol.2011.058446. Epub 2011 Jun 10.

44.

Left ventricle structural remodelling in the prediabetic Goto-Kakizaki rat.

D'Souza A, Howarth FC, Yanni J, Dobryznski H, Boyett MR, Adeghate E, Bidasee KR, Singh J.

Exp Physiol. 2011 Sep;96(9):875-88. doi: 10.1113/expphysiol.2011.058271. Epub 2011 May 27.

45.

Changing pattern of gene expression is associated with ventricular myocyte dysfunction and altered mechanisms of Ca2+ signalling in young type 2 Zucker diabetic fatty rat heart.

Howarth FC, Qureshi MA, Hassan Z, Al Kury LT, Isaev D, Parekh K, Yammahi SR, Oz M, Adrian TE, Adeghate E.

Exp Physiol. 2011 Mar;96(3):325-37. doi: 10.1113/expphysiol.2010.055574. Epub 2011 Jan 7.

46.

Heart rhythm disturbances in the neonatal alloxan-induced diabetic rat.

Howarth FC, Shafiullah M, Adeghate E, Ljubisavljevic M, Jacobson M.

Pathophysiology. 2011 Jun;18(3):185-92. doi: 10.1016/j.pathophys.2010.10.001. Epub 2010 Nov 3.

PMID:
21051208
47.

Heart rate, body temperature and physical activity are variously affected during insulin treatment in alloxan-induced type 1 diabetic rat.

Howarth FC, Jacobson M, Shafiullah M, Ljubisavljevic M, Adeghate E.

Physiol Res. 2011;60(1):65-73. Epub 2010 Oct 15.

48.

The chronic effects of neonatal alloxan-induced diabetes mellitus on ventricular myocyte shortening and cytosolic Ca2+.

Howarth FC, Hassan Z, Qureshi MA.

Mol Cell Biochem. 2011 Jan;347(1-2):71-7. doi: 10.1007/s11010-010-0613-4. Epub 2010 Oct 13.

PMID:
20941530
49.

Alloxan reduces amplitude of ventricular myocyte shortening and intracellular Ca2+ without altering L-type Ca2+ current, sarcoplasmic reticulum Ca2+ content or myofilament sensitivity to Ca2+ in Wistar rats.

Salem KA, Qureshi A, Ljubisavijevic M, Oz M, Isaev D, Hussain M, Howarth FC.

Mol Cell Biochem. 2010 Jul;340(1-2):115-23. doi: 10.1007/s11010-010-0408-7. Epub 2010 Feb 20.

PMID:
20174963
50.

The effect of a heavy exercise program on the distribution of pancreatic hormones in the streptozotocin-induced diabetic rat.

Howarth FC, Marzouqi FM, Al Saeedi AM, Hameed RS, Adeghate E.

JOP. 2009 Sep 4;10(5):485-91.

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