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Items: 21


Mutational processes shape the landscape of TP53 mutations in human cancer.

Giacomelli AO, Yang X, Lintner RE, McFarland JM, Duby M, Kim J, Howard TP, Takeda DY, Ly SH, Kim E, Gannon HS, Hurhula B, Sharpe T, Goodale A, Fritchman B, Steelman S, Vazquez F, Tsherniak A, Aguirre AJ, Doench JG, Piccioni F, Roberts CWM, Meyerson M, Getz G, Johannessen CM, Root DE, Hahn WC.

Nat Genet. 2018 Oct;50(10):1381-1387. doi: 10.1038/s41588-018-0204-y. Epub 2018 Sep 17.


Design of Experiments Methodology to Build a Multifactorial Statistical Model Describing the Metabolic Interactions of Alcohol Dehydrogenase Isozymes in the Ethanol Biosynthetic Pathway of the Yeast Saccharomyces cerevisiae.

Brown SR, Staff M, Lee R, Love J, Parker DA, Aves SJ, Howard TP.

ACS Synth Biol. 2018 Jul 20;7(7):1676-1684. doi: 10.1021/acssynbio.8b00112. Epub 2018 Jul 10.


Ash leaf metabolomes reveal differences between trees tolerant and susceptible to ash dieback disease.

Sambles CM, Salmon DL, Florance H, Howard TP, Smirnoff N, Nielsen LR, McKinney LV, Kjær ED, Buggs RJA, Studholme DJ, Grant M.

Sci Data. 2017 Dec 19;4:170190. doi: 10.1038/sdata.2017.190.


Control of sexuality by the sk1-encoded UDP-glycosyltransferase of maize.

Hayward AP, Moreno MA, Howard TP 3rd, Hague J, Nelson K, Heffelfinger C, Romero S, Kausch AP, Glauser G, Acosta IF, Mottinger JP, Dellaporta SL.

Sci Adv. 2016 Oct 28;2(10):e1600991. eCollection 2016 Oct.


Functional Genomic Characterization of Cancer Genomes.

Howard TP, Vazquez F, Tsherniak A, Hong AL, Rinne M, Aguirre AJ, Boehm JS, Hahn WC.

Cold Spring Harb Symp Quant Biol. 2016;81:237-246. doi: 10.1101/sqb.2016.81.031070. Epub 2016 Nov 4. Review.


SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2.

Kim KH, Kim W, Howard TP, Vazquez F, Tsherniak A, Wu JN, Wang W, Haswell JR, Walensky LD, Hahn WC, Orkin SH, Roberts CW.

Nat Med. 2015 Dec;21(12):1491-6. doi: 10.1038/nm.3968. Epub 2015 Nov 9.


Use of advanced recombinant lines to study the impact and potential of mutations affecting starch synthesis in barley.

Howard TP, Fahy B, Leigh F, Howell P, Powell W, Greenland A, Trafford K, Smith AM.

J Cereal Sci. 2014 Mar;59(2):196-202.


Synthetic metabolons for metabolic engineering.

Singleton C, Howard TP, Smirnoff N.

J Exp Bot. 2014 May;65(8):1947-54. doi: 10.1093/jxb/eru050. Epub 2014 Mar 3. Review.


The CP12 protein family: a thioredoxin-mediated metabolic switch?

López-Calcagno PE, Howard TP, Raines CA.

Front Plant Sci. 2014 Jan 30;5:9. doi: 10.3389/fpls.2014.00009. eCollection 2014. Review.


Identification of the maize gravitropism gene lazy plant1 by a transposon-tagging genome resequencing strategy.

Howard TP 3rd, Hayward AP, Tordillos A, Fragoso C, Moreno MA, Tohme J, Kausch AP, Mottinger JP, Dellaporta SL.

PLoS One. 2014 Jan 31;9(1):e87053. doi: 10.1371/journal.pone.0087053. eCollection 2014.


Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli.

Howard TP, Middelhaufe S, Moore K, Edner C, Kolak DM, Taylor GN, Parker DA, Lee R, Smirnoff N, Aves SJ, Love J.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7636-41. doi: 10.1073/pnas.1215966110. Epub 2013 Apr 22.


Barley mutants with low rates of endosperm starch synthesis have low grain dormancy and high susceptibility to preharvest sprouting.

Howard TP, Fahy B, Craggs A, Mumford R, Leigh F, Howell P, Greenland A, Smith AM.

New Phytol. 2012 Apr;194(1):158-67. doi: 10.1111/j.1469-8137.2011.04040.x. Epub 2012 Feb 2.


Antisense suppression of the small chloroplast protein CP12 in tobacco: a transcriptional viewpoint.

Howard TP, Upton GJ, Lloyd JC, Raines CA.

Plant Signal Behav. 2011 Dec;6(12):2026-30.


Antisense suppression of the small chloroplast protein CP12 in tobacco alters carbon partitioning and severely restricts growth.

Howard TP, Fryer MJ, Singh P, Metodiev M, Lytovchenko A, Obata T, Fernie AR, Kruger NJ, Quick WP, Lloyd JC, Raines CA.

Plant Physiol. 2011 Oct;157(2):620-31. doi: 10.1104/pp.111.183806. Epub 2011 Aug 24.


Inter-species variation in the oligomeric states of the higher plant Calvin cycle enzymes glyceraldehyde-3-phosphate dehydrogenase and phosphoribulokinase.

Howard TP, Lloyd JC, Raines CA.

J Exp Bot. 2011 Jul;62(11):3799-805. doi: 10.1093/jxb/err057. Epub 2011 Apr 15.


Thioredoxin-mediated reversible dissociation of a stromal multiprotein complex in response to changes in light availability.

Howard TP, Metodiev M, Lloyd JC, Raines CA.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):4056-61. doi: 10.1073/pnas.0710518105. Epub 2008 Mar 5.


Application of metabolite profiling to the identification of traits in a population of tomato introgression lines.

Overy SA, Walker HJ, Malone S, Howard TP, Baxter CJ, Sweetlove LJ, Hill SA, Quick WP.

J Exp Bot. 2005 Jan;56(410):287-96. Epub 2004 Dec 13.


Pneumoconiosis in a vermiculite end-product user.

Howard TP.

Am J Ind Med. 2003 Aug;44(2):214-7.


Reading the tuberculin skin test. Who, when, and how?

Howard TP, Solomon DA.

Arch Intern Med. 1988 Nov;148(11):2457-9.


Gastrobronchial fistula 36 years after thoracic trauma.

Howard TP, Solomon DA.

South Med J. 1982 Jun;75(6):751-2. No abstract available.


Fulminant respiratory failure. A manifestation of thrombotic thrombocytopenic purpura.

Howard TP.

JAMA. 1979 Jul 27;242(4):350-1. No abstract available.


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