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Items: 1 to 50 of 1159

1.

A One Health investigation of Salmonella enterica serovar Wangata in north-eastern New South Wales, Australia, 2016-2017.

Collins J, Simpson KMJ, Bell G, Durrheim DN, Hill-Cawthorne GA, Hope K, Howard P, Kohlenberg T, Lawrence K, Lilly K, Porigneaux P, Sintchenko V, Wang Q, Ward MP, Wiethoelter A, Mor SM, Flint J.

Epidemiol Infect. 2019 Jan;147:e150. doi: 10.1017/S0950268819000475.

PMID:
30869062
2.

Neurointerventional procedural complications in a growing Canadian regional stroke centre: single hospital experience analysis in the context of recommended case volumes.

Pasarikovski CR, Tanner BK, Marques AJ, da Costa L, Howard P, Dyer EE, Yang VX.

World Neurosurg. 2019 Mar 6. pii: S1878-8750(19)30560-1. doi: 10.1016/j.wneu.2019.02.137. [Epub ahead of print]

PMID:
30851466
3.

Serving and Leading, an Emergency Nurse's Legacy.

Howard PK.

J Emerg Nurs. 2019 Mar;45(2):120-121. doi: 10.1016/j.jen.2019.01.005. No abstract available.

PMID:
30846134
4.

Pipeline embolisation device with shield technology for the treatment of ruptured intracranial aneurysm.

Pasarikovski CR, Waggass G, Cardinell J, Howard P, da Costa L, Yang VX.

Neuroradiol J. 2019 Mar 6:1971400919834692. doi: 10.1177/1971400919834692. [Epub ahead of print]

PMID:
30839240
5.

Design and characterization of homogenous antibody-drug conjugates with a drug-to-antibody ratio of one prepared using an engineered antibody and a dual-maleimide pyrrolobenzodiazepine dimer.

White JB, Fleming R, Masterson L, Ruddle BT, Zhong H, Fazenbaker C, Strout P, Rosenthal K, Reed M, Muniz-Medina V, Howard P, Dixit R, Wu H, Hinrichs MJ, Gao C, Dimasi N.

MAbs. 2019 Apr;11(3):500-515. doi: 10.1080/19420862.2019.1578611. Epub 2019 Mar 5.

PMID:
30835621
6.

Bisphosphonates.

Toller CS, Charlesworth S, Mihalyo M, Howard P, Wilcock A.

J Pain Symptom Manage. 2019 Feb 6. pii: S0885-3924(19)30050-8. doi: 10.1016/j.jpainsymman.2019.01.017. [Epub ahead of print] Review. No abstract available.

PMID:
30738144
7.

Antibiotic prescribing for residents in long-term-care facilities across the UK.

Thornley T, Ashiru-Oredope D, Normington A, Beech E, Howard P.

J Antimicrob Chemother. 2019 Jan 29. doi: 10.1093/jac/dkz008. [Epub ahead of print]

8.

ARS2 is required for retinal progenitor cell S-phase progression and Müller glial cell fate specification.

O'Sullivan CS, Nickerson PEB, Krupke O, Christie J, Chen LL, Mesa-Peres M, Zhu M, Ryan B, Chow RL, Howard PL.

Biochem Cell Biol. 2019 Jan 23. doi: 10.1139/bcb-2018-0250. [Epub ahead of print]

9.

Much to Accomplish.

Howard PK.

J Emerg Nurs. 2019 Jan;45(1):1. doi: 10.1016/j.jen.2018.11.013. No abstract available.

PMID:
30616759
10.

An Alternative Focus for Route Design for the Synthesis of Antibody-Drug Conjugate Payloads.

Tiberghien AC, Howard PW, Goundry WRF, McCormick M, Parker JS.

J Org Chem. 2019 Jan 11. doi: 10.1021/acs.joc.8b02876. [Epub ahead of print]

PMID:
30602115
11.

Finding the bad actor: Challenges in identifying toxic constituents in botanical dietary supplements.

Roberts GK, Gardner D, Foster PM, Howard PC, Lui E, Walker L, van Breemen RB, Auerbach SS, Rider C.

Food Chem Toxicol. 2019 Feb;124:431-438. doi: 10.1016/j.fct.2018.12.026. Epub 2018 Dec 21. Review.

PMID:
30582954
12.

Degenerative Expansion of a Young Supergene.

Stolle E, Pracana R, Howard P, Paris CI, Brown SJ, Castillo-Carrillo C, Rossiter SJ, Wurm Y.

Mol Biol Evol. 2019 Mar 1;36(3):553-561. doi: 10.1093/molbev/msy236.

13.

An evidence-based approach to understanding the competency development needs of the health service management workforce in Australia.

Liang Z, Blackstock FC, Howard PF, Briggs DS, Leggat SG, Wollersheim D, Edvardsson D, Rahman A.

BMC Health Serv Res. 2018 Dec 18;18(1):976. doi: 10.1186/s12913-018-3760-z.

14.

Characterization and in vitro data of antibody drug conjugates (ADCs) derived from heterotrifunctional linker designed for the site-specific preparation of dual ADCs.

Kumar A, Kinneer K, Masterson L, Ezeadi E, Howard P, Wu H, Gao C, Dimasi N.

Data Brief. 2018 Nov 6;21:2208-2220. doi: 10.1016/j.dib.2018.11.005. eCollection 2018 Dec.

15.

Evaluation of Pyrrolobenzodiazepine-Loaded Nanoparticles: A Targeted Drug Delivery Approach.

Tyagi P, Pechenov S, RiosDoria J, Masterson L, Dickinson NJ, Howard P, Mao S, Harper J, Wetzel L, Yo K, Subramony JA.

J Pharm Sci. 2019 Apr;108(4):1590-1597. doi: 10.1016/j.xphs.2018.11.023. Epub 2018 Nov 22.

PMID:
30472264
16.

Mapping the Pax6 3' untranslated region microRNA regulatory landscape.

Ryan BC, Lowe K, Hanson L, Gil T, Braun L, Howard PL, Chow RL.

BMC Genomics. 2018 Nov 15;19(1):820. doi: 10.1186/s12864-018-5212-x.

17.

Synthesis of a heterotrifunctional linker for the site-specific preparation of antibody-drug conjugates with two distinct warheads.

Kumar A, Kinneer K, Masterson L, Ezeadi E, Howard P, Wu H, Gao C, Dimasi N.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3617-3621. doi: 10.1016/j.bmcl.2018.10.043. Epub 2018 Oct 26.

PMID:
30389292
18.

Electron microscopy techniques employed to explore mitochondrial defects in the developing rat brain following ketamine treatment.

Eustaquio T, Wang C, Dugard CK, George NI, Liu F, Slikker W Jr, Paule MG, Howard PC, Paredes AM.

Exp Cell Res. 2018 Dec 15;373(1-2):164-170. doi: 10.1016/j.yexcr.2018.10.009. Epub 2018 Oct 18.

19.

Preclinical assessment of an antibody-PBD conjugate that targets BCMA on multiple myeloma and myeloma progenitor cells.

Kinneer K, Flynn M, Thomas SB, Meekin J, Varkey R, Xiao X, Zhong H, Breen S, Hynes PG, Fleming R, Bezabeh B, Chen CT, Wetzel L, Chen R, Dimasi N, Tai YT, Anderson KC, Herbst R, Howard PW, Hurt EM, Tice DA.

Leukemia. 2019 Mar;33(3):766-771. doi: 10.1038/s41375-018-0278-7. Epub 2018 Oct 12. No abstract available.

PMID:
30315237
20.

Using long term mortality to determine which perioperative risk factors of mortality following hip and knee replacement may be causal.

Hunt LP, Whitehouse MR, Howard PW, Ben-Shlomo Y, Blom AW.

Sci Rep. 2018 Oct 9;8(1):15026. doi: 10.1038/s41598-018-33314-0.

21.

High Speed, High Density Intraoperative 3D Optical Topographical Imaging with Efficient Registration to MRI and CT for Craniospinal Surgical Navigation.

Jakubovic R, Guha D, Gupta S, Lu M, Jivraj J, Standish BA, Leung MK, Mariampillai A, Lee K, Siegler P, Skowron P, Farooq H, Nguyen N, Alarcon J, Deorajh R, Ramjist J, Ford M, Howard P, Phan N, Costa LD, Heyn C, Tan G, George R, Cadotte DW, Mainprize T, Yee A, Yang VXD.

Sci Rep. 2018 Oct 5;8(1):14894. doi: 10.1038/s41598-018-32424-z.

22.

Protecting Pax6 3' UTR from MicroRNA-7 Partially Restores PAX6 in Islets from an Aniridia Mouse Model.

Yongblah K, Alford SC, Ryan BC, Chow RL, Howard PL.

Mol Ther Nucleic Acids. 2018 Dec 7;13:144-153. doi: 10.1016/j.omtn.2018.08.018. Epub 2018 Sep 1.

23.

Functional Neuroanatomy of Second Language Sentence Comprehension: An fMRI Study of Late Learners of American Sign Language.

Johnson L, Fitzhugh MC, Yi Y, Mickelsen S, Baxter LC, Howard P, Rogalsky C.

Front Psychol. 2018 Sep 6;9:1626. doi: 10.3389/fpsyg.2018.01626. eCollection 2018.

24.

SLC46A3 as a Potential Predictive Biomarker for Antibody-Drug Conjugates Bearing Noncleavable Linked Maytansinoid and Pyrrolobenzodiazepine Warheads.

Kinneer K, Meekin J, Tiberghien AC, Tai YT, Phipps S, Kiefer CM, Rebelatto MC, Dimasi N, Moriarty A, Papadopoulos KP, Sridhar S, Gregson SJ, Wick MJ, Masterson L, Anderson KC, Herbst R, Howard PW, Tice DA.

Clin Cancer Res. 2018 Dec 15;24(24):6570-6582. doi: 10.1158/1078-0432.CCR-18-1300. Epub 2018 Aug 21.

PMID:
30131388
25.

Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.

DuRaine G, Wisner TW, Howard P, Johnson DC.

J Virol. 2018 Sep 26;92(20). pii: e01269-18. doi: 10.1128/JVI.01269-18. Print 2018 Oct 15.

PMID:
30068641
26.

Antitumor Activity of MEDI3726 (ADCT-401), a Pyrrolobenzodiazepine Antibody-Drug Conjugate Targeting PSMA, in Preclinical Models of Prostate Cancer.

Cho S, Zammarchi F, Williams DG, Havenith CEG, Monks NR, Tyrer P, D'Hooge F, Fleming R, Vashisht K, Dimasi N, Bertelli F, Corbett S, Adams L, Reinert HW, Dissanayake S, Britten CE, King W, Dacosta K, Tammali R, Schifferli K, Strout P, Korade M 3rd, Masson Hinrichs MJ, Chivers S, Corey E, Liu H, Kim S, Bander NH, Howard PW, Hartley JA, Coats S, Tice DA, Herbst R, van Berkel PH.

Mol Cancer Ther. 2018 Oct;17(10):2176-2186. doi: 10.1158/1535-7163.MCT-17-0982. Epub 2018 Jul 31.

PMID:
30065100
27.

Retrospective use of whole genome sequencing to better understand an outbreak of Salmonella enterica serovar Mbandaka in New South Wales, Australia.

Lindsay C, Flint J, Lilly K, Hope K, Wang Q, Howard P, Sintchenko V, Durrheim DN.

Western Pac Surveill Response J. 2018 Apr 23;9(2):20-25. doi: 10.5365/wpsar.2017.8.4.008. eCollection 2018 Apr-Jun.

28.

Levetiracetam.

Howard P, Remi J, Remi C, Charlesworth S, Whalley H, Bhatia R, Hitchens M, Mihalyo M, Wilcock A.

J Pain Symptom Manage. 2018 Oct;56(4):645-649. doi: 10.1016/j.jpainsymman.2018.07.012. Epub 2018 Jul 21.

PMID:
30036676
29.

Pre-clinical pharmacology and mechanism of action of SG3199, the pyrrolobenzodiazepine (PBD) dimer warhead component of antibody-drug conjugate (ADC) payload tesirine.

Hartley JA, Flynn MJ, Bingham JP, Corbett S, Reinert H, Tiberghien A, Masterson LA, Antonow D, Adams L, Chowdhury S, Williams DG, Mao S, Harper J, Havenith CEG, Zammarchi F, Chivers S, van Berkel PH, Howard PW.

Sci Rep. 2018 Jul 11;8(1):10479. doi: 10.1038/s41598-018-28533-4.

30.

Novel multiplex PCR assay for identification and subtyping of enteroinvasive Escherichia coli and differentiation from Shigella based on target genes selected by comparative genomics.

Dhakal R, Wang Q, Lan R, Howard P, Sintchenko V.

J Med Microbiol. 2018 Sep;67(9):1257-1264. doi: 10.1099/jmm.0.000784. Epub 2018 Jul 3.

PMID:
29969087
31.

Denosumab: AHFS 92:24.

Wilcock A, Charlesworth S, Toller CS, Girish R, Mihalyo M, Howard P.

J Pain Symptom Manage. 2018 Aug;56(2):295-301. doi: 10.1016/j.jpainsymman.2018.05.021. Epub 2018 Jun 2.

PMID:
29864491
32.

Novel Salmonella enterica Serovar Typhimurium Genotype Levels as Herald of Seasonal Salmonellosis Epidemics.

Sotomayor C, Wang Q, Arnott A, Howard P, Hope K, Lan R, Sintchenko V.

Emerg Infect Dis. 2018 Jun;24(6):1079-1082. doi: 10.3201/eid2406.171096.

33.

Seven Salmonella Typhimurium Outbreaks in Australia Linked by Trace-Back and Whole Genome Sequencing.

Ford L, Wang Q, Stafford R, Ressler KA, Norton S, Shadbolt C, Hope K, Franklin N, Krsteski R, Carswell A, Carter GP, Seemann T, Howard P, Valcanis M, Castillo CFS, Bates J, Glass K, Williamson DA, Sintchenko V, Howden BP, Kirk MD.

Foodborne Pathog Dis. 2018 May;15(5):285-292. doi: 10.1089/fpd.2017.2353. Epub 2018 Mar 20.

PMID:
29638170
34.

Development and validation of health service management competencies.

Liang Z, Howard PF, Leggat S, Bartram T.

J Health Organ Manag. 2018 Apr 9;32(2):157-175. doi: 10.1108/JHOM-06-2017-0120. Epub 2018 Feb 8.

PMID:
29624143
35.

Multidrug-Resistant Salmonella enterica 4,[5],12:i:- Sequence Type 34, New South Wales, Australia, 2016-2017.

Arnott A, Wang Q, Bachmann N, Sadsad R, Biswas C, Sotomayor C, Howard P, Rockett R, Wiklendt A, Iredell JR, Sintchenko V.

Emerg Infect Dis. 2018 Apr;24(4):751-753. doi: 10.3201/eid2404.171619.

36.

Validation of a management competency assessment tool for health service managers.

Howard PF, Liang Z, Leggat S, Karimi L.

J Health Organ Manag. 2018 Mar 19;32(1):113-134. doi: 10.1108/JHOM-08-2017-0223. Epub 2018 Feb 12.

PMID:
29508674
37.

A national quality incentive scheme to reduce antibiotic overuse in hospitals: evaluation of perceptions and impact.

Islam J, Ashiru-Oredope D, Budd E, Howard P, Walker AS, Hopkins S, Llewelyn MJ.

J Antimicrob Chemother. 2018 Jun 1;73(6):1708-1713. doi: 10.1093/jac/dky041.

PMID:
29506043
38.

Implications of Introducing New Technology: Comparative Survivorship Modeling of Metal-on-Metal Hip Replacements and Contemporary Alternatives in the National Joint Registry.

Hunt LP, Whitehouse MR, Beswick A, Porter ML, Howard P, Blom AW.

J Bone Joint Surg Am. 2018 Feb 7;100(3):189-196. doi: 10.2106/JBJS.17.00039.

PMID:
29406339
39.

Microbiological survey of commercial tattoo and permanent makeup inks available in the United States.

Nho SW, Kim SJ, Kweon O, Howard PC, Moon MS, Sadrieh NK, Cerniglia CE.

J Appl Microbiol. 2018 May;124(5):1294-1302. doi: 10.1111/jam.13713. Epub 2018 Mar 12.

PMID:
29388315
40.

Human resources estimates and funding for antibiotic stewardship teams are urgently needed: authors' response.

Pulcini C, Beovic B, Howard P, Mendelson M.

Clin Microbiol Infect. 2018 May;24(5):557. doi: 10.1016/j.cmi.2018.01.009. Epub 2018 Jan 31. No abstract available.

PMID:
29371137
41.

The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability.

Dilworth D, Gudavicius G, Xu X, Boyce AKJ, O'Sullivan C, Serpa JJ, Bilenky M, Petrochenko EV, Borchers CH, Hirst M, Swayne LA, Howard P, Nelson CJ.

Nucleic Acids Res. 2018 Mar 16;46(5):2459-2478. doi: 10.1093/nar/gky008.

42.

Incorporating Whole-Genome Sequencing into Public Health Surveillance: Lessons from Prospective Sequencing of Salmonella Typhimurium in Australia.

Ford L, Carter GP, Wang Q, Seemann T, Sintchenko V, Glass K, Williamson DA, Howard P, Valcanis M, Castillo CFS, Sait M, Howden BP, Kirk MD.

Foodborne Pathog Dis. 2018 Mar;15(3):161-167. doi: 10.1089/fpd.2017.2352. Epub 2018 Jan 16.

PMID:
29336594
43.

Is the rate of revision of 36 mm metal-on-metal total hip arthroplasties with Pinnacle acetabular components related to the year of the initial operation? an interrupted time-series analysis using data from the National Joint Registry for England and Wales.

Matharu GS, Hunt LP, Murray DW, Howard P, Pandit HG, Blom AW, Bolland B, Judge A.

Bone Joint J. 2018 Jan;100-B(1):33-41. doi: 10.1302/0301-620X.100B1.BJJ-2017-0625.R2.

PMID:
29305448
44.

ADCT-402, a PBD dimer-containing antibody drug conjugate targeting CD19-expressing malignancies.

Zammarchi F, Corbett S, Adams L, Tyrer PC, Kiakos K, Janghra N, Marafioti T, Britten CE, Havenith CEG, Chivers S, D'Hooge F, Williams DG, Tiberghien A, Howard PW, Hartley JA, van Berkel PH.

Blood. 2018 Mar 8;131(10):1094-1105. doi: 10.1182/blood-2017-10-813493. Epub 2018 Jan 3.

45.

Genetic variants in PPARGC1B and CNTN4 are associated with thromboxane A2 formation and with cardiovascular event free survival in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT).

McCarthy NS, Vangjeli C, Surendran P, Treumann A, Rooney C, Ho E, Sever P, Thom S, Hughes AD, Munroe PB, Howard P, Johnson T, Caulfield M, Shields DC, O'Brien E, Fitzgerald DJ, Stanton AV.

Atherosclerosis. 2018 Feb;269:42-49. doi: 10.1016/j.atherosclerosis.2017.12.013. Epub 2017 Dec 8.

46.

Genome Sequencing Links Persistent Outbreak of Legionellosis in Sydney (New South Wales, Australia) to an Emerging Clone of Legionella pneumophila Sequence Type 211.

Timms VJ, Rockett R, Bachmann NL, Martinez E, Wang Q, Chen SC, Jeoffreys N, Howard PJ, Smith A, Adamson S, Gilmour R, Sheppeard V, Sintchenko V.

Appl Environ Microbiol. 2018 Feb 14;84(5). pii: e02020-17. doi: 10.1128/AEM.02020-17. Print 2018 Mar 1.

47.

Computational Propaganda and Political Big Data: Moving Toward a More Critical Research Agenda.

Bolsover G, Howard P.

Big Data. 2017 Dec;5(4):273-276. doi: 10.1089/big.2017.29024.cpr. No abstract available.

48.

Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity.

Wei B, Gunzner-Toste J, Yao H, Wang T, Wang J, Xu Z, Chen J, Wai J, Nonomiya J, Tsai SP, Chuh J, Kozak KR, Liu Y, Yu SF, Lau J, Li G, Phillips GD, Leipold D, Kamath A, Su D, Xu K, Eigenbrot C, Steinbacher S, Ohri R, Raab H, Staben LR, Zhao G, Flygare JA, Pillow TH, Verma V, Masterson LA, Howard PW, Safina B.

J Med Chem. 2018 Feb 8;61(3):989-1000. doi: 10.1021/acs.jmedchem.7b01430. Epub 2017 Dec 21.

PMID:
29227683
49.

Weight gain changes in patients with aripiprazole monotherapy compared with aripiprazole-antidepressant polypharmacy in an outpatient sample.

Nguyen C, Novac A, Hazen J, Howard P, Tieu R, Bota RG.

J Psychopharmacol. 2018 Apr;32(4):423-429. doi: 10.1177/0269881117742659. Epub 2017 Dec 7.

PMID:
29215304
50.

Profiling tumour heterogeneity through circulating tumour DNA in patients with pancreatic cancer.

Adamo P, Cowley CM, Neal CP, Mistry V, Page K, Dennison AR, Isherwood J, Hastings R, Luo J, Moore DA, Howard PJ, Miguel ML, Pritchard C, Manson M, Shaw JA.

Oncotarget. 2017 Aug 14;8(50):87221-87233. doi: 10.18632/oncotarget.20250. eCollection 2017 Oct 20.

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